Characterization of common genetic variants in Cathepsin K and testing for association with bone mineral density in a large cohort of perimenopausal women from Scotland

Journal of Bone and Mineral Research

Volumn 19, Issue 1, 2004, Pages 31-41

  Giraudeau, Fabienne S ^a   Mcginnis, Ralph E ^a   Gray, Ian C ^a,b   O'Brien, Eamonn J ^a   Doncaster, Kim E ^a   Spurr, Nigel K ^c   Ralston, Stuart H ^d   Reid, David M ^d   Wood, John ^a,e  

^a GLAXOSMITHKLINE   (United Kingdom)

^b Paradigm Therapeutics Ltd   (United Kingdom)

^c GLAXOSMITHKLINE   (United States)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

^e NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Bone mineral density; Cathepsin K; Haplotype; Simple tandem repeat; Single nucleotide polymorphism

Indexed keywords

CATHEPSIN K; CATHEPSIN;

ANALYSIS OF VARIANCE; ARTICLE; BONE DENSITY; CLIMACTERIUM; CONTROLLED STUDY; DNA SEQUENCE; EXON; FEMALE; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; PREDICTION; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; TANDEM REPEAT; BODY HEIGHT; BODY MASS; BODY WEIGHT; CHEMISTRY; COHORT ANALYSIS; DINUCLEOTIDE REPEAT; FEMUR NECK; GENE LINKAGE DISEQUILIBRIUM; GENETICS; HORMONE SUBSTITUTION; LUMBAR VERTEBRA; METABOLISM; MIDDLE AGED; PHYSIOLOGY; PROSPECTIVE STUDY; REGRESSION ANALYSIS; TIME; UNITED KINGDOM;

ANALYSIS OF VARIANCE; BODY HEIGHT; BODY MASS INDEX; BODY WEIGHT; BONE DENSITY; CATHEPSINS; CLIMACTERIC; COHORT STUDIES; DINUCLEOTIDE REPEATS; FEMALE; FEMUR NECK; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HORMONE REPLACEMENT THERAPY; HUMANS; LINKAGE DISEQUILIBRIUM; LUMBAR VERTEBRAE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; SCOTLAND; TIME FACTORS;

EID: 4644293691     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.0301205     Document Type: Article

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