Structure-based development of pyridoxal propionate derivatives as specific inhibitors of cathepsin K in vitro and in vivo

Biochemical and Biophysical Research Communications

Volumn 267, Issue 3, 2000, Pages 850-854

  Katunuma, N ^a   Matsui, A ^a   Inubushi, T ^a   Murata, E ^a   Kakegawa, H ^a   Ohba, Y ^d   Turk, D ^c   Turk, V ^c   Tada, Y ^b   Asao, T ^b  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b Taiho Pharmaceutical Co Lrd   (Japan)

^c JO EF STEFAN INSTITUTE   (Slovenia)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Cathepsin K; Cathepsin S; Derivatives; Pyridoxal; Pyridoxal phosphate; Vitamin B6

Indexed keywords

CATHEPSIN B; CATHEPSIN K; CATHEPSIN L; CATHEPSIN S; COLLAGEN; HYDROLASE INHIBITOR; PROPIONIC ACID DERIVATIVE; PYRIDOXAL 5 PHOSPHATE;

ANIMAL TISSUE; ARTICLE; COLLAGEN DEGRADATION; CONTROLLED STUDY; ENZYME INHIBITION; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL; RAT;

EID: 0034719344     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1999.1953     Document Type: Article

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