In vivo detection of gastric cancer in rats by electron paramagnetic resonance imaging

Cancer Research

Volumn 64, Issue 18, 2004, Pages 6495-6502

  Mikuni, Tomiko ^a,b,c   He, Guanglong ^a,b   Petryakov, Sergey ^a,b   Fallouh, Mohanad M ^a,b   Deng, Yuanmu ^a,b   Ishihara, Ryu ^c   Kuppusamy, Periannan ^a,b   Tatsuta, Masaharu ^c   Zweier, Jay L ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c Osaka Medical Center for Cancer   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2,2,5,5 TETRAMETHYLPYRROLIDINE N OXYL (3 CARBAMOYLPROXYL)NITROXIDE 3 CARBOXAMIDE; CONTRAST MEDIUM; INDOCYANINE GREEN; METHYLNITRONITROSOGUANIDINE; NITRIC OXIDE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER DIAGNOSIS; CONTROLLED STUDY; EARLY DIAGNOSIS; ELECTRON SPIN RESONANCE; IMAGE ANALYSIS; IN VIVO STUDY; NON INVASIVE MEASUREMENT; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SPECTROSCOPY; STOMACH CANCER; STOMACH MUCOSA; TUMOR LOCALIZATION;

ANIMALS; CARCINOGENS; CYCLIC N-OXIDES; ELECTRON SPIN RESONANCE SPECTROSCOPY; INDOCYANINE GREEN; METHYLNITRONITROSOGUANIDINE; NITROGEN OXIDES; OXIDATION-REDUCTION; PYRROLIDINES; RATS; RATS, WISTAR; SPECTROSCOPY, NEAR-INFRARED; STOMACH; STOMACH NEOPLASMS;

EID: 4644286707     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-0319     Document Type: Article

References (57)

1. Trends in deaths and death rates. In: Statistics and Information Department, Vital Statistics of Japan 1999. Tokyo, Japan: Health and Welfare Statistics Association; 2001. p. 176.
2. Pisani P, Parkin DM, Bray F, Ferlay J. Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 1999;83:18-29.
3. Richardson HL. Induction of adenocarcinoma of the glandular stomach in rats by alcohol gastric lavage and feeding acetylaminofluorene. Proc Am Assoc Cancer Res 1961;2:141-2.
4. Stewart HL, Snell KC, Hare WV. Histopathogenesis of carcinoma induced in the glandular stomach of C 57 BL mice by the intranural injection of 20-methylcholanthrene. J Natl Cancer Inst (Bethesda) 1958;83:999-1019.
5. Stewart HL, Snell KC, Morris HP, Wagner BP, Ray FE. Carcinoma of the glandular stomach of rats ingesting N-N′-2.7-fluorenylenebisacetamide. J Natl Cancer Inst Monogr 1961;5:105-9.
6. Sugimura T, Fujimura S. Tumor production in glandular stomach of rat by N-methl-N′-nitro-N-nitrosoguanidine. Nature (Lond) 1967;216:943-4.
7. Mikuni T, Tatsuta M, Kamachi M. Production of hydroxyl-free radical by reaction of hydrogen peroxide with N-methyl-N′-nitro-N-nitrsoguanidine. Cancer Res 1985;45:6442-5.
8. Tatsuta M, Mikuni T, Taniguch H. Protective effect of butylated hydroxytoluene against induction of gastric cancer by N-methyl-N′-nitro-N- nitrosoguanidine in Wistar rats. Int J Cancer 1983;32:253-4.
9. Irani K, Xia Y, Zweier JL, et al. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science (Wash DC) 1997;275:1649-52.
10. Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B. A model for p53-induced apoptosis. Nature (Lond) 1997;389:300-5.
11. 2 by iron-Adriamycin. J Biol Chem 1984;259:6056-8.
12. Gianni L, Zweier JL, Levy A, Myers CE. Characterization of the cycle of iron-mediated electron transfer from Adriamycin to molecular oxygen. J Biol Chem 1985;260:6820-6.
13. Berliner LJ, Fujii H, Wan XM, Lukiewicz SJ. Feasibility study of imaging a living murine tumor by electron paramagnetic resonance. Magn Reson Med 1987;4:380-4.
14. Kazama S, Takashige G, Yoshioka H, et al. Dynamic electron spin resonance (ESR) imaging of the distribution of spin labeled dextran in a mouse. Magn Reson Med 1996;36:547-50.
15. Kuppusamy P, Chzhan M, Vij K, et al. Three-dimensional spectral-spatial EPR imaging of free radicals in the heart: a technique for imaging tissue metabolism and oxygenation. Proc Natl Acad Sci USA 1994;91:3388-92.
16. Zweier JL, Chzhan M, Samouilov A, Kuppusamy P. Electron paramagnetic resonance imaging of the rat heart. Phys Med Biol 1998;43:1823-35.
17. He G, Samouilov A, Kuppusamy P, Zweier JL. In vivo EPR imaging of the distribution and metabolism of nitroxide radicals in human skin. J Magn Reson 2001;148:155-64.
18. Rossi S, Giuntini A, Balzi M, Becciolini A, Martini G. Nitroxides and malignant human tissues: electron spin resonance in colorectal neoplastic and healthy tissues. Biochim Biophys Acta 1999;1472:1-12.
19. Chzhan M, Kuppusamy P, Zweier JL. Development of an electronically tunable L-band resonator for EPR spectroscopy and imaging of biological samples. J Magn Reson B 1995;108:67-72.
20. Zweier JL, Kuppusamy P. Electron paramagnetic resonance measurements of free radicals in the intact beating heart: a technique for detection and characterization of free radicals in whole biological tissues. Proc Natl Acad Sci USA 1988;85:5703-7.
21. Kuppusamy P, Afeworki M, Shankar RA, et al. In vivo electron paramagnetic resonance imaging of tumor heterogeneity and oxygenation in a murine model. Cancer Res 1998;58:1562-8.
22. Kuppusamy P, Ohnishi ST, Numagami Y, Ohnishi T, Zweier JL. Three-dimensional imaging of nitric oxide production in the rat brain subjected to ischemia-hypoxia. J Cereb Blood Flow Metab 1995;15:899-903.
23. Kuppusamy P, Chzhan M, Wang P, Zweier JL. Three-dimensional gated EPR imaging of the beating heart: time-resolved measurements of free radical distribution during the cardiac contractile cycle. Magn Reson Med 1996;35:323-8.
24. Chen K, Glockner JF, Morse PD, II, Swartz HM. Effects of oxygen on the metabolism of nitroxide spin labels in cells. Biochemistry 1989;28:2496-501.
25. Utsumi H, Ichikawa K, Takeshita K. In vivo ESR measurements of free radical reactions in living mice. Toxicol Lett 1995;82-83:561-5.
26. Quaresima V, Ursini CL, Gualtieri G, Sotgiu A, Ferrari M. Oxygen-dependent reduction of a nitroxide free radical by electron paramagnetic resonance monitoring of circulating rat blood. Biochim Biophys Acta 1993;1182:115-8.
27. Thomlinson RH, Gray LH. The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer 1955;9:539-49.
28. Brown JM. The hypoxic cell: a target for selective cancer therapy-eighteenth Bruce F. Cain Memorial Award lecture. Cancer Res 1999;59:5863-70.
29. Hockel M, Schlenger K, Aral B, et al. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 1996;56:4509-15.
30. Tatsuta M, Itoh T, Okuda S, Taniguchi H, Tamura H. Effect of prolonged administration of gastrin on experimental carcinogenesis in rat stomach induced by N-methyl-N ′-nitro-N-nitrosoguanidine. Cancer Res 1977;37:1808-10.
31. Kuppusamy P, Wang P, Zweier JL, et al. Electron paramagnetic resonance imaging of rat heart with nitroxide and polynitroxyl-albumin. Biochemistry 1996;35:7051-7.
32. Kuppusamy P, Chzhan M, Zweier JL. Development and optimization of three-dimensional spatial EPR imaging for biological organs and tissues. J Magn Reson B 1995;106:122-30.
33. Gurfinkel M, Thompson AB, Ralston W, et al. Pharmacokinetics of ICG and HPPH-car for the detection of normal and tumor tissue using fluorescence, near-infrared reflectance imaging: a case study. Photochem Photobiol 2000;72:94-102.
34. Tatsuta M, Iishi H, Yamamura H, et al. Effect of cimetidine on inhibition by tetragastrin of carcinogenesis induced by N-methyl-N′-nitro-N- nitrosoguanidine in Wistar rats. Cancer Res 1988;48:1591-5.
35. He G, Evalappan SP, Hirata H, et al. Mapping of the B1 field distribution of a surface coil resonator using EPR imaging. Magn Reson Med 2002;48:1057-62.
36. Blackburn RV, Spitz DR, Liu X, et al. Metabolic oxidative stress activates signal transduction and gene expression during glucose deprivation in human tumor cells. Free Radic Biol Med 1999;26:419-30.
37. Samuni A, Krishna CM, Mitchell JB, Collins CR, Russo A. Superoxide reaction with nitroxides. Free Radic Res Commun 1990;9:241-9.
38. Boyd SC, Sasame HA, Body MR. High concentrations of glutathione in glandular stomach: possible implications for carcinogenesis. Science (Wash DC) 1979;205:1010-2.
39. Hahn SM, Sullivan FJ, DeLuca AM, et al. Evaluation of tempol radioprotection in a murine tumor model. Free Radic Biol Med 1997;22:1211-6.
40. Eapen CE, Madesh M, Balasubramanian KA, et al. Mucosal mitochondrial function and antioxidant defenses in patients with gastric carcinoma. Scand J Gastroenterol 1998;33:975-81.
41. Agus DB, Vera JC, Golde DW. Stromal cell oxidation: a mechanism by which tumors obtain vitamin C. Cancer Res 1999;59:4555-8.
42. Sakaeda T, Fukumura K, Takahashi K, et al. Blood flow rate in normal and tumor-bearing rats in conscious state, under urethane anesthesia, and during systemic hypothermia. J Drug Target 1998;6:261-72.
43. Dewhirst MW. Concepts of oxygen transport at the microcirculatory level. Semin Radiat Oncol 1998;8:143-50.
44. Chaplin DJ, Olive PL, Durand RE. Intermittent blood flow in a murine tumor: radiobiological effects. Cancer Res 1987;47:597-601.
45. Takabe W, Niki E, Uchida K, et al. Oxidative stress promotes the development of transformation: involvement of a potent mutagenic lipid peroxidation product, acrolein. Carcinogenesis (Lond) 2001;22:935-41.
46. Cerutti PA. Prooxidant states and tumor promotion. Science (Wash DC) 1985;227:375-81.
47. Vallyathan V, Leonard S, Kuppusamy P, et al. Oxidative stress in silicosis: evidence for the enhanced clearance of free radicals from whole lungs. Mol Cell Biochem 1997;168:125-32.
48. Velayutham M, Li H, Kuppusamy P, Zweier JL. Mapping ischemic risk region and necrosis in the isolated heart using EPR imaging. Magn Reson Med 2003;49:1181-7.
49. Rice GC, Hoy C, Schimke RT. Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells. Proc Natl Acad Sci USA 1986;83:5978-82.
50. Shen J, Hughes C, Chao C, et al. Coinduction of glucose-regulated proteins and doxorubicin resistance in Chinese hamster cells. Proc Natl Acad Sci USA 1987;84:3278-82.
51. Hughes CS, Shen JW, Subjeck JR. Resistance to etoposide induced by three glucose-regulated stresses in Chinese hamster ovary cells. Cancer Res 1989;49:4452-4.
52. Skovsgaard T. Transport and binding of daunorubicin, Adriamycin, and rubidazone in Ehrlich ascites tumor cells. Biochem Pharmacol 1977;26:215-22.
53. Tannock I, Guttman P. Response of Chinese hamster ovary cells to anticancer drugs under aerobic and hypoxic conditions. Br J Cancer 1981;43:245-8.
54. Teicher BA, Holden SA, al-Achi A, Herman TS. Classification of antineoplastic treatments by their differential toxicity toward putative oxygenated and hypoxic tumor subpopulations in vivo in the FSaIIC murine fibrosarcoma. Cancer Res 1990;50:3339-44.
55. Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature (Lond) 1992;359:843-5.
56. Swartz HM, Walczak T. Developing in vivo EPR oximetry for clinical use. Adv Exp Med Biol 1998;454:243-52.
57. Miyake M, Liu KJ, Walczak TM, Swartz HM. In vivo EPR dosimetry of accidental exposures to radiation: experimental results indicating the feasibility of practical use in human subjects. Appl Radiat Isot 2000;52:1031-8.