Electron paramagnetic resonance imaging of the rat heart

Physics in Medicine and Biology

Volumn 43, Issue 7, 1998, Pages 1823-1835

  Zweier, Jay L ^a,b   Chzhan, Michael ^a   Samouilov, Alexandre ^a   Kuppusamy, Periannan ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; CORONARY ARTERY; DIAGNOSTIC IMAGING; ELECTRON SPIN RESONANCE; HEART MUSCLE METABOLISM; IMAGE ANALYSIS; ISOTOPE LABELING; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; RAT; THREE DIMENSIONAL IMAGING; TISSUE OXYGENATION;

ANIMALS; BIOPHYSICS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; HEART; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCARDIUM; NITRIC OXIDE; NITROGEN ISOTOPES; OXYGEN; PERFUSION; RATS;

EID: 0031865030     PISSN: 00319155     EISSN: None     Source Type: Journal    
DOI: 10.1088/0031-9155/43/7/002     Document Type: Article

References (47)

1. Alecci M, Colacicchi S, Indovina P L, Momo F, Pavone P and Sotgiu A 1990 Three-dimensional in vivo ESR imaging in rats Magn. Reson. Imaging 8 59-63
2. Alecci M, Ferrari M, Quaresima V, Sotgiu A and Ursini C L 1994 Simultaneous 280 MHz EPR imaging of rat organs during nitroxide free radical clearance Biophys. J. 67 1274-9
3. Berliner L J 1992 Magnetic resonance spectroscopy: methods and applications in material science, agriculture and biomedicine Magnetic Resonance Microscopy ed B Blumich and W Kuhn (Weinheim: VCH) pp 151-63
4. Chen K, Ng C E, Zweier J L, Kuppusamy P, Glickson J D and Swartz H M 1994 Measurement of the intracellular concentration of oxygen in a cell perfusion system Magn. Reson. Med. 31 1-5
5. Chzhan M, Kuppusamy P and Zweier J L 1995 Development of an electronically tunable L-band resonator for EPR spectroscopy and imaging of biological samples. J. Magn. Reson. B 108 67-72
6. Chzhan M, Shteynbuk M, Kuppusamy P and Zweier J L 1993 An optimized L-band resonator for EPR imaging of biological samples J. Magn. Reson. A 105 49-53
7. Colacicchi S, Ferrari M and Sotgiu A 1992 In vivo EPR spectroscopy/imaging: first experiences, problems, and perspectives Int. J. Biochem. 24 205-14
8. Eaton G R, Eaton S S and Ohno K (ed) 1991 EPR Imaging and In Vivo EPR (Boca Raton, FL: CRC Press)
9. Ewert U and Herrling T 1986 Spectrally-resolved EPR tomography with stationary gradient Chem. Phys. Lett. 129 516
10. Ewert U, Herrling T and Schneider W 1988 EPR imaging Magnetic Resonance and Related Phenomena, 24th Ampere Conf. (Poznan) pp 281-94
11. Froncisz W and Hyde J S 1982 The loop-gap resonator, a new microwave lumped circuit ESR sample structure J. Magn. Reson. 47 515-21
12. Fujii H and Berliner L J 1985 One- and two-dimensional EPR imaging studies on phantoms and plant specimens Magn. Reson. Med. 2 275-82
13. Halpern H J, Spencer D P, Polen J V, Bowman M K, Nelson A C, Dowey E M and Teicher E A 1989 Imaging radio frequency electron spin resonance spectrometer with high resolution and sensitivity for in vivo measurements Rev. Sci. Instrum. 60 1040
14. Kuppusamy P, Chzhan M, Samouilov A, Wang P and Zweier J L 1995a Mapping the spin density and lineshape distribution of free radicals using 4D spectral-spatial EPR imaging J. Magn. Reson. B 107 116-25
15. Kuppusamy P, Chzhan M, Vij K, Shteynbuk M, Lefer D J, Giannella E and Zweier J L 1994 3-D spectral-spatial EPR imaging of free radicals in the heart: a technique for imaging tissue metabolism and oxygenation Proc. Natl. Acad. Sci. USA 91 3388-92
16. Kuppusamy P, Chzhan M, Wang P and Zweier J L 1996a Three-dimensional gated EPR imaging of the beating heart: time-resolved measurements of free radical distribution during the cardiac contractile cycle Magn. Reson. Med. 35 323-28
17. Kuppusamy P, Chzhan M and Zweier J L 1995b Development and optimization of three-dimensional spatial EPR imaging for biological samples and tissues J. Magn. Reson. B 106 122-30
18. _1995c 3D and 4D electron paramagnetic resonance imaging of the rat heart Magn. Reson. Med. (Japan) 6 59-61
19. Kuppusamy P, Ohnishi S T, Numagami Y, Ohnishi T and Zweier J L 1995d Three-dimensional imaging of nitric oxide production in the rat brain subjected to ischemia-hypoxia J. Cereb. Blood Flow Metab. 15 899-903
20. _1996b Imaging of nitric oxide generation in the brain Res. Chem. Interm. 22 605-13
21. Kuppusamy P, Wang P, Samouilov A and Zweier J L 1996c Spatial mapping of nitric oxide in the ischemic heart using electron paramagnetic resonance imaging Magn. Reson. Med. 36 212-18
22. Kuppusamy P, Wang P and Zweier J L 1995e Three-dimensional spatial EPR imaging of the rat heart Magn. Reson. Med. 34 99-105
23. _1997 High resolution electron paramagnetic resonance imaging of biological samples with a single line paramagnetic label Magn. Reson. Med. 37 479-83
24. Kuppusamy P, Wang P, Zweier J L, Krishna C M, Mitchell J B, Ma L, Trimble C and Hsia C J 1996d EPR imaging of rat heart with nitroxide and a polynitroxylated albumin Biochem. 35 7051-7
25. Kuppusamy P and Zweier J L 1995 EPR imaging of free radicals in the perfused heart Curr. Topics Biophys. 18 3-13
26. _1996a A forward subtraction procedure for removing hyperfine artifacts in electron paramagnetic resonance imaging Magn. Reson. Med. 35 316-22
27. _1996b Hyperfine artifacts in electron paramagnetic resonance imaging Res. Chem. Interm. 22 593-604
28. Lukiewicz S J and Lukiewicz S G 1984 In vivo ESR spectroscopy of large biological objects Magn. Reson. Med. 1 297-8
29. Maltempo M M, Eaton S S and Eaton G R 1987 Spectral spatial two-dimensional imaging J. Magn. Reson. 72 449-55
30. Marr R B, Chen C N and Lauterbur P C 1981 On two approaches to 3D reconstruction in NMR zeugmatography Mathematical Aspects of Computerized Tomography vol 8 ed G T Herman and F Natterer (New York: Springer) p 225
31. Ohno K 1987 ESR imaging Magn. Reson, Rev. 11 275-310
32. Schauer D A, Desrosiers M F, Kuppusamy P and Zweier J L Radiation dosimetry of an accidental overexposure using EPR spectrometry and imaging of human bone Appl. Radiat. Isotop. at press
33. Sotgiu A 1985 Resonator design for in vivo ESR spectroscopy J. Magn. Reson. 65 206-14
34. Sotgiu A and Gualtieri G 1985 Cavity resonator for in vivo ESR spectroscopy J. Phys. E: Sci. Instrum. 18 899-901
35. Subczynski W, Lukiewicz S J and Hyde J S 1986 Murine in vivo L-band ESR spin label oximetry with a loop-gap resonator Magn. Reson. Med. 3 747-54
36. Takeshita K, Utsumi H and Hamada A 1991 ESR measurement of radical clearance in lung of whole mouse Biophys. Res. Comm. 177 874-80
37. Testa L, Gultieri G and Sotgiu A 1993 Electron paramagnetic resonance imaging of a model of a beating heart Phys. Med. Biol 38 259-66
38. Woods R K, Bacic G C, Lauterbur P C and Swartz H M 1989 Three-dimensional electron spin resonance imaging J. Magn. Reson. 84 247
39. Woods R K, Hyslop W B, Maar R B and Lauterbur P C 1991 Image reconstruction EPR Imaging and In Vivo EPR ed G R Eaton, S S Eaton and K Ohno (Boca Raton, FL: CRC Press) ch 10, pp 91-117
40. Zweier J L, Chzhan M, Ewert U, Schneider G and Kuppusamy P 1994 Development of a highly sensitive probe for measuring oxygen in biological tissues J. Magn. Reson. B 105 52-7
41. Zweier J L, Flaherty J T and Weisfeldt M L 1987 Direct measurement of free radical generation following reperfusion of ischemic myocardium Proc. Natl. Acad. Sci. USA 84 1404-7
42. Zweier J L and Jacobus W E 1987 Substrate-induced alterations of high energy phosphate metabolism and contractile function in the perfused heart J. Biol. Chem. 262 8015-21
43. Zweier J L and Kuppusamy P 1988 Electron paramagnetic resonance measurements of free radicals in the intact beating heart: a technique for detection and characterization of free radicals in whole biological tissues Proc. Natl. Acad. Sci. USA 85 5703
44. Zweier J L, Kuppusamy P, Williams R, Rayburn B K, Smith D, Weisfeldt M L and Flaherty J T 1989 Measurement and characterization of postischemic free radical generation in the isolated perfused heart J. Biol. Chem. 264 18 890-5
45. Zweier J L, Wang P, Chzhan M and Kuppusamy P 1996 Spatial and spectral-spatial imaging of free radicals and oxygen in the heart Res. Chem. Interm. 22 615-24
46. Zweier J L, Wang P and Kuppusamy P 1995a Direct measurement of nitric oxide generation in the ischemic heart using electron paramagnetic resonance spectroscopy J. Biol. Chem. 270 304-7
47. Zweier J L, Wang P, Samoilov A and Kuppusamy P 1995b Enzyme independent formation of nitric oxide in biological tissues Nature Med. 1 804-9