Early changes in glial reactivity and lipid peroxidation in diabetic rat retina: Effects of melatonin

Acta Diabetologica

Volumn 41, Issue 3, 2004, Pages 123-128

  Baydas, G ^a   Tuzcu, M ^a   Yasar, A ^a   Baydas, B ^b  

^a FIRAT UNIVERSITY   (Turkey)

^b YUZUNCU YIL UNIVERSITY   (Turkey)

Author keywords

Diabetes; Glial fibrillary acidic protein; Lipid peroxidation; Melatonin; Retina

Indexed keywords

ALKENE DERIVATIVE; DRUG VEHICLE; GLIAL FIBRILLARY ACIDIC PROTEIN; MALONALDEHYDE; MELATONIN; SODIUM CHLORIDE; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG EFFECT; DRUG MECHANISM; GLIA CELL; IMMUNOHISTOCHEMISTRY; INJECTION; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATION; PATHOGENESIS; PATHOPHYSIOLOGY; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; RAT; RETINOPATHY;

ANIMALS; BLOOD GLUCOSE; CHOLESTEROL; DIABETES MELLITUS, EXPERIMENTAL; GLIAL FIBRILLARY ACIDIC PROTEIN; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; MELATONIN; NEUROGLIA; RATS; RATS, WISTAR; RETINA; TRIGLYCERIDES;

EID: 4644284529     PISSN: 09405429     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00592-004-0155-x     Document Type: Article

References (42)

1. Gispen WH, Biessels GJ (2000) Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci 23:542-549
2. McCall AL (1992) The impact of diabetes on the CNS. Diabetes 41:557-570
3. Biessels GJ, Kapessa AC, Bravenboer B, Erkelens DW, Gispen WH (1994) Cerebral function in diabetes mellitus. Diabetologia 37:643-650
4. Bresnick GH (1986) Diabetic retinopathy viewed as a neurosensory disorder. Arch Ophthalmol 104:989-990
5. Coupland SG (1987) A comparison of oscillatory potential and pattern electroretinogram measures in diabetic retinopathy. Doc Ophthalmol 66:207-218
6. Sakai H, Tani Y, Shirasawa E, Shirao Y, Kawasaki K (1995) Development of electroretinographic alterations in streptozotocin-induced diabetes in rats. Ophthalmic Res 27:57-63
7. Obrosova IG, Fathallah L, Greene DA (2000) Early changes in lipid peroxidation and antioxidative defense in diabetic rat retina: effect of DL-alpha-lipoic acid. Eur J Pharmacol 398:139-146
8. Agardh CD, Agardh E, Qian Y, Hultberg B (1998) Glutathione levels are reduced in diabetic rat retina but are not influenced by ischemia followed by recirculation. Metabolism 47:269-272
9. Montgomery DL (1994) Astrocytes: form, functions, and roles in disease. Vet Pathol 31:145-167
10. Newman E, Reichenbach A (1996) The Muller cell: a functional element of the retina. Trends Neurosci 19:307-312
11. Drukarch B, Schepens E, Stoof JC, Langeveld CH, Van Muiswinkel FL (1998) Astrocyte-enhanced neuronal survival is mediated by scavenging of extracellular reactive oxygen species. Free Radic Biol Med 25:217-220
12. Lieth E, Barber AJ, Xu B, Dice C, Ratz MJ, Tanase D, Strother JM (1998) Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group. Diabetes 47:815-820
13. Acarin L, González B, Hidalgo J, Castro AJ, Castellano B (1999) Primary cortical glial reaction versus secondary thalamic glial response in the excitotoxically injured young brain: Astroglial response and metallothionein expression. Neuroscience 92:827-839
14. Agardh E, Bruun A, Agardh CD (2001) Retinal glial cell immunoreactivity and neuronal cell changes in rats with STZ-induced diabetes. Curr Eye Res 23:276-284
15. Baydas G, Canatan H, Turkoglu A (2002) Comparative analysis of the protective effects of melatonin and vitamin E on streptozocin-induced diabetes mellitus. J Pineal Res 32:225-230
16. Abdel-Wahab MH, Abd-Allah AR (2000) Possible protective effect of melatonin and/or desferrioxamine against Streptozotocin-induced hyperglycaemia in mice. Pharmacol Res 41:533-537
17. Tan DX, Chen LD, Poeggeler B, Manchester LC, Reiter RJ (1993) Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocrine J 1:57-60
18. Reiter RJ, Tan DX, Cabrera J, D'Arpa D, Sainz RM, Mayo JC, Ramos S (1999) The oxidant/antioxidant network: role of melatonin. Biol Signals Recep 8:56-63
19. Reiter RJ (1998) Oxidative damage in the central nervous system: protection by melatonin, Prog Neurobiol 56:359-384
20. Donder E, Baydas G, Ozkan Y, Ercel E, Yalniz M, Dogan H (1999) Investigation of antioxidant effect of melatonin against carbon tetrachloride toxicity in various tissues. Biomed Res 10:141-145
21. Okatani Y, Wakatsuki A, Reiter RJ, Miyahara Y (2002) Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse. Neurobiol Aging 23:639-644
22. Reiter RJ, Acuna-Castroviejo D, Tan DX, Burkhardt S (2001) Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system. Ann N Y Acad Sci 939:200-215
23. Baydas G, Ercel E, Canatan H, Donder E, Akyol A (2001) Effect of melatonin on oxidative status of rat brain, liver and kidney tissues under constant light exposure. Cell Biochem Funct 19:37-41
24. Baydas G, Reiter RJ, Nedzvetskii VS, Nerush PA, Kirichenko SV (2002) Altered glial fibrillary acidic protein content and its degradation in the hippocampus, cortex and cerebellum of rats exposed to constant light: reversal by melatonin. J Pineal Res 33:134-138
25. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
26. Nedzvetskii VS, Berezich VA, Oberniak TI, Zhmareva EN (1986) Characteristics of specific intermediate filament proteins in human brain tumors. Biokhimiia 51:1843-1850
27. Ellman GL (1959) Tissue sulphydryl groups. Arch Biochem Biophys 82:70-77
28. Baydas G, Canatan H, Turkoglu A (2002) Comparative analysis of the protective effects of melatonin and vitamin E on streptozotocin-induced diabetes mellitus. J Pineal Res 32: 225-230
29. Abdel-Wahab MH, Abd-Allah AR (2000) Possible protective effect of melatonin and/or desferrioxamine against streptozotocin-induced hyperglycaemia in mice. Pharmacol Res 41:533-537
30. Siu AW, Reiter RJ, To CH (1998) The efficacy of vitamin E and melatonin as antioxidants against lipid peroxidation in rat retinal homogenates. J Pineal Res 24(4):239-244
31. Barber AJ, Antonetti DA, Gardner TW (2000) Altered expression of retinal occludin and glial fibrillary acidic protein in experimental diabetes. The Penn State Retina Research Group. Invest Ophthalmol Vis Sci 41:3561-3568
32. Rungger-Brandle E, Dosso AA, Leuenberger PM (2000) Glial reactivity, an early feature of diabetic retinopathy. Invest Ophthalmol Vis Sci 41:1971-1980
33. Kaneko K, Nakamura A, Yoshida K, Kametani F, Higuchi K, Ikeda S (2002) Glial fibrillary acidic protein is greatly modified by oxidative stress in aceruloplasminemia brain. Free Radic Res 36:303-306
34. Lee MC, Chung YT, Lee JH, Jung JJ, Kim HS, Kim SU (2001) Antioxidant effect of melatonin in human retinal neuron cultures. Exp Neurol 172:407-415
35. Anwar MM, Moustafa MA (2001) The effect of melatonin on eye lens of rats exposed to ultraviolet radiation. Comp Biochem Physiol C Toxicol Pharmacol 129:57-63
36. Baydas G, Gursu MF, Yilmaz S, Canpolat S, Yasar A, Cikim G, Canatan H (2002) Daily rhythm of glutathione peroxidase activity, lipid peroxidation and glutathione levels in tissues of pinealectomized rats. Neurosci Lett 3:195-198
37. Baydas G, Gursu MF, Cikim G, Canpolat S, Yasar A, Canatan H, Kelestimur H (2002) Effects of pinealectomy on the levels and the circadian rhythm of plasma homocysteine in rats. 33:151-155
38. Hussain S, Slikker W Jr, Ali SF (1996) Role of metallothionein and other antioxidants in scavenging superoxide radicals and their possible role in neuroprotection. Neurochem Int 29:145-152
39. Baydas G, Reiter RJ, Nedzvetskii VS, Yasar A, Tuzcu M, Ozveren F, Canatan H (2003) Melatonin protects the central nervous system of rats against toluene-containing thinner intoxication by reducing reactive gliosis. Toxicol Lett 137:169-174
40. Montgomery DL (1994) Astrocytes: form, functions, and roles in disease. Vet Pathol 31:145-167
41. Gardner TW, Lieth E, Khin SA, Barber AJ, Bonsall DJ, Lesher T, Rice K, Brennan WA Jr (1997) Astrocytes increase barrier properties and ZO-1 expression in retinal vascular endothelial cells. Invest Ophthalmol Vis Sci 38:2423-2427
42. Garner A (1993) Histopathology of diabetic retinopathy in man. Eye 7:250-253