Melatonin protects the central nervous system of rats against toluene-containing thinner intoxication by reducing reactive gliosis

Toxicology Letters

Volumn 137, Issue 3, 2003, Pages 169-174

  Baydas, Giyasettin ^a   Reiter, Russel J ^b   Nedzvetskii, Viktor S ^c   Yaşar, Abdullah ^a   Tuzcu, Mehmet ^a   Ozveren, Faik ^a   Canatan, Halit ^a  

^a FIRAT UNIVERSITY   (Turkey)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c OLES HONCHAR DNIPRO NATIONAL UNIVERSITY   (Ukraine)

Author keywords

Cortex; Glial fibrillary acidic protein; Hippocampus; Lipid peroxidation; Melatonin; Toluene

Indexed keywords

4 HYDROXYALKENAL; ANTIOXIDANT; CELL MARKER; CHEMICAL COMPOUND; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; MALONALDEHYDE; MELATONIN; REACTIVE OXYGEN METABOLITE; SCAVENGER; THINNER; TOLUENE; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN LEVEL; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CONTROLLED STUDY; DRUG MECHANISM; FUME; GLIA CELL; GLIOSIS; HIPPOCAMPUS; INHALATION; INTOXICATION; LIPID PEROXIDATION; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; TIME; VAPOR; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; GLUTATHIONE; HIPPOCAMPUS; LIPID PEROXIDATION; MALE; MELATONIN; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; SOLVENTS; TOLUENE;

EID: 0037415377     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(02)00400-9     Document Type: Article

References (39)

1. Acuña-Castroviejo D., Martin M., Macias M., Escames G., Leon J., Khaldy H., Reiter R.J. Melatonin, mitochondria, and cellular bioenergetics. J. Pineal Res. 30:2001;65-74.
2. Baelum J. Human solvent exposure: factors influencing the pharmacokinetics and acute toxicity. Pharmacol. Toxicol. 1:1991;1-36.
3. Baydas G., Canatan H., Turkoglu A. Comparative analysis of the protective effects of melatonin and vitamin E on streptozocin-induced diabetes mellitus. J. Pineal Res. 4:2002;225-230.
4. Baydas G., Gursu M.F., Yilmaz S., Canpolat S., Yasar A., Cikim G., Canatan H. Daily rhythm of glutathione peroxidase activity, lipid peroxidation and glutathione levels in tissues of pinealectomized rats. Neurosci. Lett. 3:2002;195-198.
5. Baydas G., Ercel E., Canatan H., Donder E., Akyol A. Effect of melatonin on oxidative status of rat brain, liver and kidney tissues under constant light exposure. Cell Biochem. Funct. 19:2001;37-41.
6. Borlongan C.V., Yamamoto M., Takei N., Kumazaki M., Ungsuparkorn C., Hida H., Sanberg P.R., Nishino H. Glial cell survival is enhanced during melatonin-induced neuroprotection against cerebral ischemia. FASEB J. 10:2000;1307-1317.
7. Bridges R.J., Koh J.Y., Hatalski C.G., Cotman C.W. Increased excitotoxic vulnerability of cortical cultures with reduced levels of glutathione. Eur. J. Pharmacol. 326:1991;199-200.
8. Burmistrov S.O., Arutyunyan A.V., Stepanov M.G., Oparina T.I., Prokopenko V.M. Effect of chronic inhalation of toluene and dioxane on activity of free radical processes in rat ovaries and brain. Bull. Exp. Biol. Med. 3:2001;832-836.
9. +-induced neurodegeneration and glutathione impairment in the nigrostriatal dopaminergic pathway. J. Pineal Res. 32:2002;262-269.
10. Cuzzocrea S., Reiter R.J. Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury. Eur. J. Pharmacol. 426:2001;1-10.
11. Donder E., Baydas G., Sokmen S., Ercel E., Yalniz M., Dogan H., Bahcecioglu I.H. Investigation of antioxidant and glucometabolic effects of melatonin in experimental diabetes mellitus. Biomed. Res. 10:1999;127-132.
12. Donder E., Baydas G., Ozkan Y., Ercel E., Yalniz M., Dogan H. Investigation of antioxidant effect of melatonin against carbon tetrachloride toxicity in various tissues. Biomed. Res. 10:1999;141-145.
13. Ellman G.L. Tissue sulphydryl groups. Arch. Biochem. Biophys. 82:1959;70-77.
14. Escobar A., Aruffo C. Chronic thinner intoxication: clinico-pathologic report of a human case. J. Neurol. Neurosurg. Psychiat. 43:1980;986-994.
15. Gotohda T., Tokunaga I., Kubo S., Morita K., Kitamura O., Eguchi A. Effect of toluene inhalation on astrocytes and neurotrophic factor in rat brain. Forensic Sci. Int. 11:2000;233-238.
16. Halks-Miller M., Henderson M., Eng L.F. Alpha tocopherol decreases lipid peroxidation, neuronal necrosis, and reactive gliosis in reaggregate cultures of fetal rat brain. J. Neuropathol. Exp. Neurol. 4:1986;471-484.
17. Hass U., Lund S.P., Hougaard K.S., Simonsen L. Developmental neurotoxicity after toluene inhalation exposure in rats. Neurotoxicol. Teratol. 4:1999;349-357.
18. Herrera F., Sainz R.M., Mayo J.C., Martin V., Antolin I., Rodriquez C. Glutamate induces oxidative stress not mediated by glutamate receptors or cysteine transporters: protective effect of melatonin and other antioxidants. J. Pineal Res. 31:2001;356-362.
19. Janeczko K. Spatiotemporal patterns of the astroglial proliferation in rat brain injured at the postmitotic stage of postnatal development: a combined immunocytochemical and autoradiographic study. Brain Res. 485:1989;236-243.
20. Janeczko K. Co-expression of GFAP and vimentin in astrocytes proliferating in response to injury in the mouse cerebral hemisphere: a combined autoradiographic and double immunocytochemical study. Int. J. Dev. Neurosci. 11:1993;139-147.
21. Ladefoged O., Strange P., Moller A., Lam H.R., Ostergaard G., Larsen J.J., Arlien-Soborg P. Irreversible effects in rats of toluene (inhalation) exposure for six months. Pharmacol. Toxicol. 5:1991;384-390.
22. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
23. Makar T.K., Nedergaard M., Preuss A., Gelbard A.S., Perumal A.S., Cooper A.J. Vitamin E, ascorbate, glutathione disulfide and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain. J. Neurochem. 62:1994;45-53.
24. Mattia C.J., Ali S.F., Bondy S.C. Toluene-induced oxidative stress in several brain regions and other organs. Mol. Chem. Neuropathol. 3:1993;313-328.
25. Mattia C.J., Adams J.D. Jr., Bondy S.C. Free radical induction in the brain and liver by products of toluene catabolism. Biochem. Pharmacol. 1:1993;103-110.
26. Moonen G., Rogister B., Leprince P., Rigo J.M., Delree P., Lefebvre P.P., Schoenen J. Neuro-glial interactions and neural plasticity. Prog. Brain Res. 86:1990;63-73.
27. Nedzvetski V.S., Berezich V.A., Oberniak T.I., Zhmareva E.N. Characteristics of specific intermediate filament proteins in human brain tumours. Biokhimiia. 51:1986;1843-1850.
28. Okatani Y., Wakatsuki A., Reiter R.J., Miyahara Y. Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse. Neurobiol. Aging. 23:2002;639-644.
29. Papadopoulos M.C., Koumenis I.L., Yuan T.Y., Giffard R.G. Primary cortical glial reaction versus secondary thalamic glial response in the excitotoxically injured young brain: astroglial response and metallothionein expression. Neuroscience. 92:1999;827-839.
30. Poeggeler B., Thuermann S., Rose A., Schoenke M., Burkhardt S., Hardeland R. Melatonin's unique radical scavenging properties - roles of its functional substituents are revealed by a comparison with its structural analogues. J. Pineal Res. 33:2002;20-30.
31. Raps S.P., Lai J.C., Hertz L., Cooper A.J. Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons. Brain Res. 593:1989;398-401.
32. Reiter R.J. Oxidative damage in the central nervous system: protection by melatonin. Prog. Neurobiol. 56:1998;359-384.
33. Reiter R.J., Acuña-Castroviejo D., Tan D.X., Burkhardt S. Free radical-mediated molecular damage: mechanisms for the protective actions of melatonin in the central nervous system. Ann. NY Acad. Sci. 939:2001;200-215.
34. Reiter R.J., Tan D.X., Manchester L.C., Qi W. Biochemical reactivity of melatonin with reactive oxygen and nitrogen species. Cell Biochem. Biophys. 34:2001;237-256.
35. Savolainen H. Superoxide dismutase and glutathione peroxidase activities in rat brain. Res. Commun. Chem. Pathol. Pharmacol. 21:1978;173-176.
36. Shen Y.X., Xu S.Y., Wei W., Sun X.X., Liu L.H., Yang J., Dong C. The protective effects of melatonin from oxidative damage induced by amyloid beta-peptide 25-35 in middle aged rats. J. Pineal Res. 32:2002;85-89.
37. Tan D.X., Reiter R.J., Manchester L.C., Yan M.T., El-Sawi M., Sainz R.M., Mayo J.C., Kohen R., Allegra M., Hardeland R. Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr. Topics. Med. Chem. 2:2002;181-198.
38. Urata Y., Honma S., Goto S., Todoroki S., Ueda T., Cho T., Honma K., Kondo T. Melatonin induces γ-glutamylcysteine synthase mediated by activator protein-1 in human vascular endothelial cells. Free Rad. Biol. Med. 27:1999;838-847.
39. Wakatsuki A., Okatani Y., Shinohara K., Ikenoue N., Kaneda C., Fukaya T. Melatonin protects fetal rat brain against oxidative mitochondria damage. J. Pineal Res. 30:2001;22-28.