메뉴 건너뛰기




Volumn 10, Issue 4, 2004, Pages 768-779

Side-by-side comparison of lentivirally transduced and mRNA-electroporated dendritic cells: Implications for cancer immunotherapy protocols

Author keywords

Antigen presentation; Dendritic cell; IL 12; Immunotherapy; Lentivirus; mRNA electroporation

Indexed keywords

INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; TUMOR ANTIGEN; VIRUS VECTOR;

EID: 4644275422     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.07.017     Document Type: Article
Times cited : (72)

References (56)
  • 1
    • 0034041033 scopus 로고    scopus 로고
    • Immunobiology of dendritic cells
    • J. Banchereau et al. Immunobiology of dendritic cells Annu. Rev. Immunol. 18 2000 767-811
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 767-811
    • Banchereau, J.1
  • 2
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • J. Banchereau R.M. Steinman Dendritic cells and the control of immunity Nature 392 1998 245-252
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 3
    • 0344076299 scopus 로고    scopus 로고
    • Generation of large numbers of fully mature and stable dendritic cells from leukapheresis products for clinical application
    • B. Thurner et al. Generation of large numbers of fully mature and stable dendritic cells from leukapheresis products for clinical application J. Immunol. Methods 223 1999 1-15
    • (1999) J. Immunol. Methods , vol.223 , pp. 1-15
    • Thurner, B.1
  • 4
    • 0343022266 scopus 로고    scopus 로고
    • Adenoviral transduction of human 'clinical grade' immature dendritic cells enhances costimulatory molecule expression and T-cell stimulatory capacity
    • H. Rouard et al. Adenoviral transduction of human 'clinical grade' immature dendritic cells enhances costimulatory molecule expression and T-cell stimulatory capacity J. Immunol. Methods. 241 2000 69-81
    • (2000) J. Immunol. Methods. , vol.241 , pp. 69-81
    • Rouard, H.1
  • 5
    • 0035527586 scopus 로고    scopus 로고
    • Comparison of monocyte enrichment by immuno-magnetic depletion or adherence for the clinical-scale generation of DC
    • Y. Suen et al. Comparison of monocyte enrichment by immuno-magnetic depletion or adherence for the clinical-scale generation of DC Cytotherapy 3 2001 365-375
    • (2001) Cytotherapy , vol.3 , pp. 365-375
    • Suen, Y.1
  • 6
    • 0036606341 scopus 로고    scopus 로고
    • Generation of large numbers of dendritic cells in a closed system using cell factories
    • S. Tuyaerts et al. Generation of large numbers of dendritic cells in a closed system using cell factories J. Immunol. Methods. 264 2002 135-151
    • (2002) J. Immunol. Methods , vol.264 , pp. 135-151
    • Tuyaerts, S.1
  • 7
    • 0030026776 scopus 로고    scopus 로고
    • Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells
    • F.J. Hsu et al. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells Nat. Med. 2 1996 52-58
    • (1996) Nat. Med. , vol.2 , pp. 52-58
    • Hsu, F.J.1
  • 8
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
    • F.O. Nestle et al. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells Nat. Med. 4 1998 328-332
    • (1998) Nat. Med. , vol.4 , pp. 328-332
    • Nestle, F.O.1
  • 9
    • 0033051081 scopus 로고    scopus 로고
    • Dendritic cell vaccines for cancer immunotherapy
    • J.M. Timmerman R. Levy Dendritic cell vaccines for cancer immunotherapy Annu. Rev. Med.. 50 1999 507-529
    • (1999) Annu. Rev. Med. , vol.50 , pp. 507-529
    • Timmerman, J.M.1    Levy, R.2
  • 10
    • 0036448032 scopus 로고    scopus 로고
    • Therapeutic vaccination against metastatic renal cell carcinoma by autologous dendritic cells: Preclinical results and outcome of a first clinical phase I/II trial
    • A. Marten et al. Therapeutic vaccination against metastatic renal cell carcinoma by autologous dendritic cells: preclinical results and outcome of a first clinical phase I/II trial Cancer Immunol. Immunother. 51 2002 637-644
    • (2002) Cancer Immunol. Immunother. , vol.51 , pp. 637-644
    • Marten, A.1
  • 11
    • 0036734775 scopus 로고    scopus 로고
    • The treatment of patients with disseminated malignant melanoma by vaccination with autologous cell hybrids of tumor cells and dendritic cells
    • S.W. Krause et al. The treatment of patients with disseminated malignant melanoma by vaccination with autologous cell hybrids of tumor cells and dendritic cells J. Immunother. 25 2002 421-428
    • (2002) J. Immunother. , vol.25 , pp. 421-428
    • Krause, S.W.1
  • 12
    • 0029145983 scopus 로고
    • Expression of endogenous peptide-major histocompatibility complex class II complexes derived from invariant chain-antigen fusion proteins
    • S. Sanderson K. Frauwirth N. Shastri Expression of endogenous peptide-major histocompatibility complex class II complexes derived from invariant chain-antigen fusion proteins Proc. Natl. Acad. Sci. USA 92 1995 7217-7221
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7217-7221
    • Sanderson, S.1    Frauwirth, K.2    Shastri, N.3
  • 13
    • 0029583864 scopus 로고
    • Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens
    • T.C. Wu et al. Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens Proc. Natl. Acad. Sci. USA 92 1995 11671-11675
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11671-11675
    • Wu, T.C.1
  • 14
    • 0031962522 scopus 로고    scopus 로고
    • High efficiency adenovirus-mediated gene transfer to human dendritic cells
    • A.B. Dietz S. Vuk-Pavlovic High efficiency adenovirus-mediated gene transfer to human dendritic cells Blood 91 1998 392-398
    • (1998) Blood , vol.91 , pp. 392-398
    • Dietz, A.B.1    Vuk-Pavlovic, S.2
  • 15
    • 0030639411 scopus 로고    scopus 로고
    • A comparison of gene transfer methods in human dendritic cells
    • J.F. Arthur et al. A comparison of gene transfer methods in human dendritic cells Cancer Gene Ther. 4 1997 17-25
    • (1997) Cancer Gene Ther. , vol.4 , pp. 17-25
    • Arthur, J.F.1
  • 17
    • 0029753767 scopus 로고    scopus 로고
    • Retroviral transduction of human dendritic cells with a tumor-associated antigen gene
    • M.E. Reeves R.E. Royal J.S. Lam S.A. Rosenberg P. Hwu Retroviral transduction of human dendritic cells with a tumor-associated antigen gene Cancer Res. 56 1996 5672-5677
    • (1996) Cancer Res. , vol.56 , pp. 5672-5677
    • Reeves, M.E.1    Royal, R.E.2    Lam, J.S.3    Rosenberg, S.A.4    Hwu, P.5
  • 18
    • 0032953409 scopus 로고    scopus 로고
    • + T cell help to elicit protective and therapeutic antitumor immunity
    • + T cell help to elicit protective and therapeutic antitumor immunity J. Immunol. 162 1999 144-151
    • (1999) J. Immunol. , vol.162 , pp. 144-151
    • De Veerman, M.1
  • 19
    • 0141427829 scopus 로고    scopus 로고
    • Clinical protocol. Immunization of patients with malignant melanoma with autologous CD34(+) cell-derived dendritic cells transduced ex vivo with a recombinant replication-deficient vaccinia vector encoding the human tyrosinase gene: A phase I trial
    • M. Di Nicola et al. Clinical protocol. Immunization of patients with malignant melanoma with autologous CD34(+) cell-derived dendritic cells transduced ex vivo with a recombinant replication-deficient vaccinia vector encoding the human tyrosinase gene: a phase I trial Hum. Gene Ther. 14 2003 1347-1360
    • (2003) Hum. Gene Ther. , vol.14 , pp. 1347-1360
    • Di Nicola, M.1
  • 20
    • 0032197463 scopus 로고    scopus 로고
    • Gene transfer into human dendritic antigen-presenting cells by vaccinia virus and adenovirus vectors
    • M. Di Nicola et al. Gene transfer into human dendritic antigen-presenting cells by vaccinia virus and adenovirus vectors Cancer Gene Ther. 5 1998 350-356
    • (1998) Cancer Gene Ther. , vol.5 , pp. 350-356
    • Di Nicola, M.1
  • 21
    • 0034283912 scopus 로고    scopus 로고
    • Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors
    • N. Chinnasamy et al. Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors Hum. Gene Ther. 11 2000 1901-1909
    • (2000) Hum. Gene Ther. , vol.11 , pp. 1901-1909
    • Chinnasamy, N.1
  • 22
    • 0034663035 scopus 로고    scopus 로고
    • Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIV-specific cytotoxic T-lymphocyte response in vitro
    • A. Gruber J. Kan-Mitchell K.L. Kuhen T. Mukai F. Wong-Staal Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIV-specific cytotoxic T-lymphocyte response in vitro Blood 96 2000 1327-1333
    • (2000) Blood , vol.96 , pp. 1327-1333
    • Gruber, A.1    Kan-Mitchell, J.2    Kuhen, K.L.3    Mukai, T.4    Wong-Staal, F.5
  • 23
    • 0034135980 scopus 로고    scopus 로고
    • Transduction of human PBMC-derived dendritic cells and macrophages by an HIV-1-based lentiviral vector system
    • R. Schroers et al. Transduction of human PBMC-derived dendritic cells and macrophages by an HIV-1-based lentiviral vector system Mol. Ther. 1 2000 171-179
    • (2000) Mol. Ther. , vol.1 , pp. 171-179
    • Schroers, R.1
  • 24
    • 0842312143 scopus 로고    scopus 로고
    • Lentivirally transduced dendritic cells as a tool for cancer immunotherapy
    • K. Breckpot et al. Lentivirally transduced dendritic cells as a tool for cancer immunotherapy J. Gene Med. 5 2003 654-667
    • (2003) J. Gene Med. , vol.5 , pp. 654-667
    • Breckpot, K.1
  • 25
    • 0035169569 scopus 로고    scopus 로고
    • Lentivirus-transduced human monocyte-derived dendritic cells efficiently stimulate antigen-specific cytotoxic T lymphocytes
    • J. Dyall J.B. Latouche S. Schnell M. Sadelain Lentivirus-transduced human monocyte-derived dendritic cells efficiently stimulate antigen-specific cytotoxic T lymphocytes Blood 97 2001 114-121
    • (2001) Blood , vol.97 , pp. 114-121
    • Dyall, J.1    Latouche, J.B.2    Schnell, S.3    Sadelain, M.4
  • 26
    • 0036288752 scopus 로고    scopus 로고
    • Efficient transduction of dendritic cells and induction of a T-cell response by third-generation lentivectors
    • C. Esslinger P. Romero H.R. MacDonald Efficient transduction of dendritic cells and induction of a T-cell response by third-generation lentivectors Hum. Gene Ther. 13 2002 1091-1100
    • (2002) Hum. Gene Ther. , vol.13 , pp. 1091-1100
    • Esslinger, C.1    Romero, P.2    MacDonald, H.R.3
  • 27
    • 0036371235 scopus 로고    scopus 로고
    • Use of a lentiviral flap vector for induction of CTL immunity against melanoma: Perspectives for immunotherapy
    • H. Firat et al. Use of a lentiviral flap vector for induction of CTL immunity against melanoma: perspectives for immunotherapy J. Gene Med. 4 2002 38-45
    • (2002) J. Gene Med. , vol.4 , pp. 38-45
    • Firat, H.1
  • 28
    • 0030819379 scopus 로고    scopus 로고
    • Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
    • R. Zufferey D. Nagy R.J. Mandel L. Naldini D. Trono Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo Nat. Biotechnol. 15 1997 871-875
    • (1997) Nat. Biotechnol. , vol.15 , pp. 871-875
    • Zufferey, R.1    Nagy, D.2    Mandel, R.J.3    Naldini, L.4    Trono, D.5
  • 29
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging system
    • T. Dull et al. A third-generation lentivirus vector with a conditional packaging system J. Virol. 72 1998 8463-8471
    • (1998) J. Virol. , vol.72 , pp. 8463-8471
    • Dull, T.1
  • 31
    • 0032978712 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
    • R. Zufferey J.E. Donello D. Trono T.J. Hope Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors J. Virol. 73 1999 2886-2892
    • (1999) J. Virol. , vol.73 , pp. 2886-2892
    • Zufferey, R.1    Donello, J.E.2    Trono, D.3    Hope, T.J.4
  • 32
    • 0034663381 scopus 로고    scopus 로고
    • Lentiviral-mediated gene transfer into human lymphocytes: Role of HIV-1 accessory proteins
    • D. Chinnasamy et al. Lentiviral-mediated gene transfer into human lymphocytes: role of HIV-1 accessory proteins Blood 96 2000 1309-1316
    • (2000) Blood , vol.96 , pp. 1309-1316
    • Chinnasamy, D.1
  • 33
    • 0034040751 scopus 로고    scopus 로고
    • Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
    • A. Follenzi L.E. Ailles S. Bakovic M. Geuna L. Naldini Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences Nat. Genet. 25 2000 217-222
    • (2000) Nat. Genet. , vol.25 , pp. 217-222
    • Follenzi, A.1    Ailles, L.E.2    Bakovic, S.3    Geuna, M.4    Naldini, L.5
  • 34
    • 0034646513 scopus 로고    scopus 로고
    • HIV-1 genome nuclear import is mediated by a central DNA flap
    • V. Zennou et al. HIV-1 genome nuclear import is mediated by a central DNA flap Cell 101 2000 173-185
    • (2000) Cell , vol.101 , pp. 173-185
    • Zennou, V.1
  • 35
    • 7144250527 scopus 로고    scopus 로고
    • Nonviral transfection of distinct types of human dendritic cells: High-efficiency gene transfer by electroporation into hematopoietic progenitor- but not monocyte-derived dendritic cells
    • V.F. VanTendeloo et al. Nonviral transfection of distinct types of human dendritic cells: high-efficiency gene transfer by electroporation into hematopoietic progenitor- but not monocyte-derived dendritic cells Gene Ther. 5 1998 700-707
    • (1998) Gene Ther. , vol.5 , pp. 700-707
    • VanTendeloo, V.F.1
  • 36
    • 0035412401 scopus 로고    scopus 로고
    • Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
    • V.F. VanTendeloo et al. Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells Blood 98 2001 49-56
    • (2001) Blood , vol.98 , pp. 49-56
    • VanTendeloo, V.F.1
  • 37
    • 0031960397 scopus 로고    scopus 로고
    • Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA
    • S.K. Nair et al. Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA Nat. Biotechnol. 16 1998 364-369
    • (1998) Nat. Biotechnol. , vol.16 , pp. 364-369
    • Nair, S.K.1
  • 38
    • 0036049777 scopus 로고    scopus 로고
    • mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation
    • P. Ponsaerts et al. mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation Leukemia 16 2002 1324-1330
    • (2002) Leukemia , vol.16 , pp. 1324-1330
    • Ponsaerts, P.1
  • 39
    • 0036844382 scopus 로고    scopus 로고
    • Nonviral and viral gene transfer into different subsets of human dendritic cells yield comparable efficiency of transfection
    • A. Lundqvist et al. Nonviral and viral gene transfer into different subsets of human dendritic cells yield comparable efficiency of transfection J. Immunother. 25 2002 445-454
    • (2002) J. Immunother. , vol.25 , pp. 445-454
    • Lundqvist, A.1
  • 40
    • 0036708241 scopus 로고    scopus 로고
    • Efficient genetic modification of murine dendritic cells by electroporation with mRNA
    • S. VanMeirvenne Efficient genetic modification of murine dendritic cells by electroporation with mRNA Cancer Gene Ther. 9 2002 787-797
    • (2002) Cancer Gene Ther. , vol.9 , pp. 787-797
    • VanMeirvenne, S.1
  • 41
    • 0141564862 scopus 로고    scopus 로고
    • Induction of influenza matrix protein 1 and melanA-specific T lymphocytes in vitro using mRNA-electroporated dendritic cells
    • S. Tuyaerts et al. Induction of influenza matrix protein 1 and melanA-specific T lymphocytes in vitro using mRNA-electroporated dendritic cells Cancer Gene Ther. 10 2003 696-706
    • (2003) Cancer Gene Ther. , vol.10 , pp. 696-706
    • Tuyaerts, S.1
  • 42
    • 0033693387 scopus 로고    scopus 로고
    • + cytolytic T lymphocytes
    • + cytolytic T lymphocytes Cancer Res. 60 2000 6272-6275
    • (2000) Cancer Res. , vol.60 , pp. 6272-6275
    • Schultz, E.S.1
  • 43
    • 0035084353 scopus 로고    scopus 로고
    • A MAGE-3 peptide recognized on HLA-B35 and HLA-A1 by cytolytic T lymphocytes
    • E.S. Schultz et al. A MAGE-3 peptide recognized on HLA-B35 and HLA-A1 by cytolytic T lymphocytes Tissue Antigens. 57 2001 103-109
    • (2001) Tissue Antigens. , vol.57 , pp. 103-109
    • Schultz, E.S.1
  • 44
    • 0032942068 scopus 로고    scopus 로고
    • Dendritic cells transfected with the nef genes of HIV-1 primary isolates specifically activate cytotoxic T lymphocytes from seropositive subjects
    • D. Chassin et al. Dendritic cells transfected with the nef genes of HIV-1 primary isolates specifically activate cytotoxic T lymphocytes from seropositive subjects Eur. J. Immunol. 29 1999 196-202
    • (1999) Eur. J. Immunol. , vol.29 , pp. 196-202
    • Chassin, D.1
  • 46
    • 0030845528 scopus 로고    scopus 로고
    • Recombinant retroviruses pseudotyped with the vesicular stomatitis virus G glycoprotein mediate both stable gene transfer and pseudotransduction in human peripheral blood lymphocytes
    • H.F. Gallardo C. Tan D. Ory M. Sadelain Recombinant retroviruses pseudotyped with the vesicular stomatitis virus G glycoprotein mediate both stable gene transfer and pseudotransduction in human peripheral blood lymphocytes Blood 90 1997 952-957
    • (1997) Blood , vol.90 , pp. 952-957
    • Gallardo, H.F.1    Tan, C.2    Ory, D.3    Sadelain, M.4
  • 47
    • 0029931982 scopus 로고    scopus 로고
    • Pseudotransduction of hepatocytes by using concentrated pseudotyped vesicular stomatitis virus G glycoprotein (VSV-G)-Moloney murine leukemia virus-derived retrovirus vectors: Comparison of VSV-G and amphotropic vectors for hepatic gene transfer
    • M.L. Liu B.L. Winther M.A. Kay Pseudotransduction of hepatocytes by using concentrated pseudotyped vesicular stomatitis virus G glycoprotein (VSV-G)-Moloney murine leukemia virus-derived retrovirus vectors: comparison of VSV-G and amphotropic vectors for hepatic gene transfer J. Virol. 70 1996 2497-2502
    • (1996) J. Virol. , vol.70 , pp. 2497-2502
    • Liu, M.L.1    Winther, B.L.2    Kay, M.A.3
  • 49
    • 0033453239 scopus 로고    scopus 로고
    • Attenuation of green fluorescent protein half-life in mammalian cells
    • P. Corish C. Tyler-Smith Attenuation of green fluorescent protein half-life in mammalian cells Protein Eng. 12 1999 1035-1040
    • (1999) Protein Eng. , vol.12 , pp. 1035-1040
    • Corish, P.1    Tyler-Smith, C.2
  • 50
    • 0344667552 scopus 로고    scopus 로고
    • NF-kappaB activation pathways induced by T cell costimulation
    • M.L. Schmitz S. Bacher O. Dienz NF-kappaB activation pathways induced by T cell costimulation 17 2003 2187-2193
    • (2003) FASEB J. , vol.17 , pp. 2187-2193
    • Schmitz, M.L.1    Bacher, S.2    Dienz, O.3
  • 51
    • 0035990373 scopus 로고    scopus 로고
    • IL-12 secreting dendritic cells are required for optimum activation of human secondary lymphoid tissue T cells
    • H. Rouard et al. IL-12 secreting dendritic cells are required for optimum activation of human secondary lymphoid tissue T cells J. Immunother. 25 2002 324-333
    • (2002) J. Immunother. , vol.25 , pp. 324-333
    • Rouard, H.1
  • 52
    • 0037220470 scopus 로고    scopus 로고
    • + T cells present within the microenvironment of human lung tumors are mobilized by the local and sustained release of IL-12 to kill tumors in situ by indirect effects of IFN-gamma
    • + T cells present within the microenvironment of human lung tumors are mobilized by the local and sustained release of IL-12 to kill tumors in situ by indirect effects of IFN-gamma J. Immunol. 170 2003 400-412
    • (2003) J. Immunol. , vol.170 , pp. 400-412
    • Hess, S.D.1
  • 53
    • 0037371133 scopus 로고    scopus 로고
    • Inhibition of TCR-induced CD8 T cell death by IL-12: Regulation of Fas ligand and cellular FLIP expression and caspase activation by IL-12
    • S.W. Lee Y. Park J.K. Yoo S.Y. Choi Y.C. Sung Inhibition of TCR-induced CD8 T cell death by IL-12: regulation of Fas ligand and cellular FLIP expression and caspase activation by IL-12 J. Immunol. 170 2003 2456-2460
    • (2003) J. Immunol. , vol.170 , pp. 2456-2460
    • Lee, S.W.1    Park, Y.2    Yoo, J.K.3    Choi, S.Y.4    Sung, Y.C.5
  • 55
    • 4644223873 scopus 로고    scopus 로고
    • Activation of monocytes via the CD14 receptor leads to the enhanced lentiviral transduction of immature dendritic cells
    • Breckpot A. et al. Activation of monocytes via the CD14 receptor leads to the enhanced lentiviral transduction of immature dendritic cells Hum. Gene Ther. 15 2004 562-573
    • (2004) Hum. Gene Ther. , vol.15 , pp. 562-573
    • Breckpot, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.