Real-time detection of 13C NMR labeling kinetics in perfused EMT6 mouse mammary tumor cells and βHC9 mouse insulinomas

Biotechnology and Bioengineering

Volumn 87, Issue 7, 2004, Pages 835-848

  Mancuso, Anthony ^a   Beardsley, N J ^a   Wehrli, S ^c   Pickup, S ^a   Matschinsky, F M ^b   Glickson, J D ^a  

^a B6 Blockley Hall ^*  (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

13C NMR; 31P NMR; Cultured cells; EMT6; Insulinoma; TCA cycle

Indexed keywords

METABOLISM; NUCLEAR MAGNETIC RESONANCE; POLYPEPTIDES; REACTION KINETICS; REAL TIME SYSTEMS; SIGNAL TO NOISE RATIO; TRANSPORT PROPERTIES; TUMORS;

INTRACELLULAR COMPOUNDS; MICROCARRIERS; TUMOR CELLS;

BIOTECHNOLOGY;

CARBON 13; CITRATE SYNTHASE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; POLYPEPTIDE;

ANIMAL CELL; ARTICLE; BREAST TUMOR; CARBON NUCLEAR MAGNETIC RESONANCE; CELL ADHESION; CITRIC ACID CYCLE; CONTROL SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; GLYCOLYSIS; IMMOBILIZED CELL; INSULINOMA; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN TRANSPORT; PACKED BED REACTOR; SIGNAL NOISE RATIO;

ANIMALS; CARBON ISOTOPES; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELLS, IMMOBILIZED; GLUCOSE; GLUTAMIC ACID; INSULINOMA; ISOTOPE LABELING; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MAMMARY NEOPLASMS, EXPERIMENTAL; METABOLIC CLEARANCE RATE; MICE; ONLINE SYSTEMS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 4644265452     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20191     Document Type: Article

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