Autism spectrum disorders: An overview

Advances in Pediatrics

Volumn 51, Issue , 2004, Pages 63-109

  Goldson, Edward ^a  

^a CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIDEPRESSANT AGENT; BUSPIRONE; CARBAMAZEPINE; CLOMIPRAMINE; CLONIDINE; FLUOXETINE; MEASLES MUMPS RUBELLA VACCINE; NALTREXONE; NEUROLEPTIC AGENT; OPIATE ANTAGONIST; RISPERIDONE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; VALPROIC ACID;

AGGRESSION; AKATHISIA; AUTISM; BEHAVIOR; CHROMOSOME ABERRATION; CLINICAL TRIAL; CONSTIPATION; DIAGNOSTIC PROCEDURE; DISEASE CLASSIFICATION; DISEASE EXACERBATION; DISEASE SEVERITY; DYSKINESIA; DYSPHAGIA; FATIGUE; GASTROINTESTINAL SYMPTOM; GENETICS; HEARING IMPAIRMENT; HUMAN; IMMUNIZATION; INCIDENCE; INCREASED APPETITE; INTELLIGENCE QUOTIENT; INTERPERSONAL COMMUNICATION; MENTAL DEFICIENCY; MOOD DISORDER; MOTOR PERFORMANCE; MUSCLE RIGIDITY; NEUROBIOLOGY; REVIEW; SEIZURE; SENSORY SYSTEM; SEROTONIN SYNDROME; SIDE EFFECT; SLEEP DISORDER; TREMOR; URINE RETENTION; WEIGHT GAIN; CHILD;

AUTISTIC DISORDER; CHILD; HUMANS;

EID: 4644245026     PISSN: 00653101     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review

References (118)

1. Kanner L: Autistic disturbances of affective contact. Nerv Child 2:217-250, 1943.
2. Kanner L: Problems of nosology and psychodynamics of early infantile autism. Am J Orthopsychiatr 19:416-426, 1949.
3. Bettelheim B: The Empty Fortress: Infantile Autism and the Birth of the Self. New York, Free Press, 1967.
4. Volkmar FR, Lord C: Diagnosis and definition of autism and other pervasive developmental disorders, in Volkmar FR (ed): Autism and Pervasive Developmental Disorders. Cambridge, England, Cambridge University Press, 1998, pp 5-40.
5. Gabriels RL: Therapy: Laying the foundation for individual and family growth, in Gabriels RL, Hill DE (eds): Autism: From Research to Individual Practice. London, Jessica Kingsley, 2002, pp 91-126.
6. Ozonoff S, Rogers SJ: From Kanner to the millenium, in Ozonoff S, Rogers SJ, Hendren RL (eds): Autism Spectrum Disorders: A Research Review for Practioners. Washington, DC, American Psychiatric Publishing, 2003, pp 3-33.
7. Aicardi J: Autism and autistic-like conditions, in Aicardi J (ed): Diseases of the Nervous System in Children, ed 2. Cambridge, England, University Press, 1998, p 827.
8. American Academy Pediatrics: The pediatrician's role in the diagnosis and management of autistic spectrum disorder in children. Pediatrics 107:1221-1226, 2001.
9. American Psychiatric Association: Diagnostic and Statistical Manual Of Mental Disorders, Fourth Edition (DSM-IV-TR). Washington, DC, American Psychiatric Association, 2000.
10. Wing L, Gould J: Severe impairments of social interaction and associated abnormalities in children: Epidemiology and classification. J Autism Dev Disord 9:11-29, 1979.
11. Cohen DJ, Volkmar FR (eds): Handbook of Autism and Pervasive Developmental Disorders, ed 2. New York, John Wiley, 1997.
12. Gillberg C, Coleman M: The Biology of the Autistic Syndromes. London, MacKeith Press, 2000.
13. Gabriels RL, Hill DE (eds): Autism: From Research to Individual Practice. London, Jessica Kingsley, 2002.
14. Ozonoff S, Rogers SJ, Hendren RL (eds): Autism Spectrum Disorders: A Research Review for Practioners. Washington, DC, American Psychiatric Publishing, 2003.
15. Lam CW, Yeung WL, Ko CH, et al: Spectrum of mutations in the MECP2 gene in patients with infantile autism and Rett syndrome. J Med Genet 37:E41, 2000.
16. Bauman ML: Brief report: Neuroanatomic observations of the brain in pervasive developmental disorders. J Autism Dev Disord 26:199-203, 1996.
17. Caronna EB, Halfon N: Dipping deeper into the reservoir of autism spectrum disorder. Arch Pediatr Adolesc Med 157:619-622, 2003.
18. Fombonne E: Epidemiological surveys of autism and other pervasive developmental disorders: An update. J Autism Dev Disord 33:365-382, 2003.
19. Fombonne E: The prevalence of autism. JAMA 289:87-89, 2003.
20. Bertrand J, Mars A, Boyle C, et al: Prevalence of autism in a United States population: The Brick Township, New Jersey, investigation. Pediatrics 108:1155-1161, 2001.
21. Yeargin-Allsopp M, Karapurkar T, et al: Prevalence of autism in a US metropolitan area. JAMA 289:49-55, 2003.
22. Gurney JG, Frtiz MS, Ness KK, et al: Analysis of prevalence trends of autism spectrum disorder in Minnesota. Arch Pediatr Adolesc Med 157:622-627, 2003.
23. Croen LA, Grether JK, Hoogstrate J, et al: The changing prevalence of autism in California. J Autism Dev Disord 32:207-215, 2002.
24. Fombonne E: Is there an epidemic of autism (commentary)? Pediatrics 107:411-413, 2001.
25. Fombonne E: Epidemiological trends in rates of autism. Mol Psychiatry 7:S4-S6, 2002.
26. National Research Council, Committee on Educational Interventions for Children With Autism, Division of Behavioral and Social Sciences and Education. Lord C, McGee JP (eds): Educating Children With Autism. Washington, DC, National Academy Press, 2001.
27. Bernard S, Enayati A, Redwood L, et al: Autism: A novel form of mercury poisoning. Med Hypotheses 56:462-471, 2001.
28. Nelson KB, Bauman ML: Thimerosal and autism (commentary)? Pediatrics 112:674-679, 2003.
29. Pichichero ME, Cernichiari E, Lopreiato J, et al: Mercury concentrations and metabolism in infants receiving vaccines containing thimersal: A descriptive study. Lancet 360:1737-1741, 2002.
30. Ball LK, Ball R, Pratt RD: An assessment of thimerosal use in childhood vaccines. Pediatrics 107:1147-1154, 2001.
31. Freed GL, Andreae MC, Cowan AE, et al: The process of public policy formulation: the case of thimerosal vaccine. Pediatrics 109:1153-1159, 2002.
32. Clarkson TW, Magos L, Myers GJ: The toxicology of mercury: Current exposures and clinical manifestations. N Engl J Med 349:1731-1737, 2003.
33. Madsen KM, Lauritsen M, Pedersen CB, et al: Thimerosal and the occurrence of autism: Negative ecological evidence from Danish population-based studies. Pediatrics 112:604-606, 2003.
34. Wakefield AJ, Murch SH, Anthony A, et al: Ileal-lymphoid-nodular hyperplasia, non-specific colitis and pervasive-developmental disorder in children. Lancet 351:637-641, 1998.
35. Halsey NA, and the Conference Writing Panel: Measles-mumps-rubella vaccine and autistic spectrum disorder: Report from the New Challenges in Childhood Immunization Conference, Oak Brook, Ill, June 12-13, 2000. Pediatrics 107:e84, 2001.
36. Fombonne E, Chakrabati S: No evidence for a new variant of measles-mumps-rubella induced autism. Pediatrics 108:e58, 2001.
37. Fombonne E, Cook EH Jr: MMR and autistic enterocolitis: Consistent epidemiological failure to find an association. Mol Psychiatry 8:133-134, 2003.
38. Dales L, Hammer SJ, Smith NJ: Time trends in autism and MMR immunization coverage in California. JAMA 285:1183-1185, 2001.
39. Taylor B, Miller E, Farrington CP: Autism and measles, mumps and rubella vaccine: No epidemiologic evidence for a causal association. Lancet 353:2026-2029, 1999.
40. Baird G, Charman T, Cox A, et al: Screening and surveillance for autism and pervasive developmental disorders. Arch Dis Child 84:468-475, 2001.
41. Rogers SJ: Neuropsychology of autism in young children and its implications for early intervention. Ment Retard Dev Disabil Res Rev 4:104-112, 1998.
42. Dawson G, Osterling J: Early intervention in autism, in Guralnick MJ (ed): The Effectiveness of Early Intervention. Baltimore, Md, Paul H Brookes, 1997, pp 307-326.
43. Lord C, Risi S: Diagnosis of autism spectrum disorders in young children, in Wetherby AM, Prizant BM (eds): Autism Spectrum Disorders: A Transactional Developmental Perspective. Baltimore, Paul H Brookes, 2000, pp 11-30.
44. Shinar S, Rapin I, Arnold S, et al: Language regression in childhood. Pediatr Neurol 24:183-189, 2001.
45. Ornitz EM, Guthrie D, Farley AH: The early development of autistic children. J Autism Child Schizophr 7:207-229, 1977.
46. Gillberg C, Coleman M: Diagnosis in infancy, in Gillberg C, Coleman M (eds): The Biology of the Autistic Syndromes. London, MacKeith Press, 2000, pp 53-62.
47. Osterling J, Dawson G: Early recognition of children with autism: A study of first birthday home videotapes. J Autism Dev Disord 24:247-257, 1994.
48. Adrien JL, Faaure M, Perrot A, et al: Blind ratings of early symptoms of autism based upon family home movies. J Am Acad Child Adolesc Psychiatry 33:617-625, 1993.
49. Osterling JA, Dawson G, Munson JA: Early recognition of 1-year old infants with autism spectrum disorder versus mental retardation. Dev Psychopathol 14:239-251, 2002.
50. Baron-Cohen S, Allen J, Gillberg C: Can autism be detected at 18 months? The needle, the haystack, and the CHAT. Br J Psychiatry 161:839-843, 1992.
51. Robins DL, Fein D, Barton ML, et al: The Modified Checklist for Autism in Toddlers: An initial study investigation the early detection of autism and pervasive developmental disorders. J Autism Dev Disord 31:131-144, 2001.
52. Gillam JE: Gillam Autism Rating Scale (GARS). Austin, Tex, Pro-Ed, 1995.
53. Schopler E, Reichler R, Rochen-Renner B: The Childhood Autism Rating Scale (CARS). Los Angeles, Western Psychological Services, 1988.
54. Lord C, Rutter M, Le Couteur A: Autism Diagnostic Interview - Revised: A revised version of the diagnostic interview for caregivers and individuals with possible pervasive developmental disorders. J Autism Dev Disord 24:659-685, 1994.
55. Lord C, Risi S, Lambrecht L, et al: The Autism Diagnostic Schedule - Generic: A standard measure of social and communication deficits associated with the spectrum of autism. J Autism Dev Disord 30:205-223, 2000.
56. Spence MA: The genetics of autism. Curr Opin Pediatr 13:561-565, 2001.
57. Rutter M, Bailey A, Simonoff E, et al: Genetic influences and autism, in Cohen DJ, Volkmar FR (eds): Handbook of Autism and Pervasive Developmental Disorders, ed 2. New York, John Wiley, 1997, pp 370-401.
58. Dawson G, Webb S, Schellenberg GD, et al: Defining the broader phenotype of autism: Genetic, brain, and behavioral perspectives. Dev Psychopathol 14:581-611, 2002.
59. Gillberg C, Coleman M: The epidemiology of autism and its spectrum disorders, The Biology of the Autistic Syndromes. London, MacKeith Press, 2000, pp 85-101.
60. Schroer RJ, Phelan MC, Michaelis RC, et al: Autism and maternally derived aberrations of chromosome 15q. Am J Med Genet 76:327-336, 1998.
61. Smith M, Filipek PA, Wu C, et al: Analysis of a 1-megabase deletion in 15q22-123 in an autistic patient: Identification of candidate genes for autism and of homologous DNA segments in 15q22-q23 and 15q11-q13. Am J Med Genet 96:765-770, 2000.
62. Lauritsen M, Mors O, Mortensen PB, et al: Infantile autism and associated chromosome abnormalities: A register-based study and a literature survey. J Child Psychol Psychiatry 40:335-345, 1999.
63. Gillberg C, Gillberg IC, Steffenburg S: Siblings and parents of children with autism: A controlled population-based study. Dev Med Child Neurol 34:389-398, 1992.
64. Hebb DO: The Organization of Behavior: A Neuropsychological Theory. New York, John Wiley, 1949.
65. Hall SS: Is Buddhism good for your health? New York Times Magazine, September 14, 2003, pp 46-49.
66. Kemper TL, Bauman M: Neuropathology of infantile autism. J Neuropathol Exp Neurol 57:645-652, 1998.
67. Fombonne E, Rogé B, Claverie J, et al: Microcephaly and macrocephaly in autism. J Autism Dev Disord 29:113-119, 1999.
68. Piven J, Arndt S, Bailey J, et al: An MRI study of brain size in autism. Am J Psychiatry 152:1145-1149, 1995.
69. Piven J, Arndt S, Bailey J, et al: Regional brain enlargement in autism: A magnetic resonance imaging study. J Am Acad Child Adolesc Psychiatry 35:530-536, 1996.
70. Filipek PA: Neuroimaging in the developmental disorders: The state of the science. J Child Psychol Psychiatry 40:113-128, 1999.
71. Rodier PM: Converging evidence for brain stem injury in autism. Dev Psychopathol 14:537-557, 2002.
72. Steffenburg S: Neuropsychiatric assessment of children with autism: A population-based study. Dev Med Child Neurol 33:495-501, 1991.
73. Gillberg C, Coleman M: Autism and medical disorders: A review of the literature. Dev Med Child Neurol 3:191-202, 1996.
74. Mars AE, Mauk JE, Dowrick PW: Symptoms of pervasive developmental disorders as observed in prediagnostic home videos of infants and toddlers. J Pediatr 132:500-504, 1998.
75. Filipek PA, Accardo PJ, Ashwal S, et al: The screening and diagnosis of autistic spectrum disorders. J Autism Dev Disord 29:439-484, 1999.
76. Hagerman RJ: Neurodevelopmental Disorders: Diagnosis and Treatment. New York, Oxford University Press, 1999.
77. Kanner L: Follow-up study of eleven children originally reported in 1943. J Autism Child Schizophr 1:119-145, 1971.
78. Rapin I: Autism. N Engl J Med 337:97-103, 1997.
79. Tuchman R: Treatment of seizure disorders and EEG abnormalities in children with autism spectrum disorders. J Autism Dev Disord 30:485-489, 2000.
80. Gillberg C, Coleman M: Epilepsy and electrophysiology, in Gillberg C, Coleman M (eds): The Biology of the Autistic Syndromes. London, MacKeith Press, 2000, pp 185-196.
81. Page T: Metabolic approaches to the treatment of autism spectrum disorders. J Autism Dev Disord 30:463-469, 2000.
82. Page T: Potential neurobiologic mechanisms through which metabolic disorders could related to autism (commentary). J Autism Dev Disord 30:471-473, 2000.
83. Rapin I: Autistic regression and disintegrative disorder: How important is the role of epilepsy. Semin Pediatr Neurol 24:278-285, 1995.
84. Rapin I, Katzman R: Neurobiology of autism. Ann Neurol 43:7-14, 1998.
85. Tuchman R, Rapin I: Regression in pervasive developmental disorders: Seizures and epileptiform electroencephalogram correlates. Pediatrics 99:560-566, 1997.
86. Landau WM, Kleffner F: Syndrome of acquired aphasia with convulsive disorder in children. Neurology 7:523-530, 1957.
87. Mantovani JF: Autistic regression and Landau-Kleffner syndrome: Progress or confusion. Dev Med Child Neurol 42:349-353, 2000.
88. Tuchman R: Acquired epileptiform aphasias. Semin Pediatr Neurol 4:93-101, 1997.
89. Horvath K, Papadimitriou JC, Rabsztyn A, et al: Gastrointestinal abnormalities in children with autistic disorder. J Pediatr 135:559-563, 1999.
90. Quigley EM, Hurley D: Autism and the gastrointestinal tract. Am J Gastroenterol 95:2154-2156, 2000.
91. Kudo T, Nelson K: How common are gastrointestinal disorders in children with autism? Curr Opin Pediatr 15:339-343, 2003.
92. Gillberg C, Coleman M: The disease entities of autism, in Gillberg C, Coleman M (eds): The Biology of the Autistic Syndromes. London, MacKeith Press, 2000, pp 118-135.
93. Wakefield AJ, Anthony A, Murch SH: Enterocolitis in children with developmental disorders. Am J Gastroenterol 95:2285-2295, 2000.
94. Furlano RI, Anthony A, Day R, et al: Colonic CD8 and gamma theta T-cell infiltration with epithelial damage in children with autism. J Pediatr 138:366-372, 2001.
95. Horvath K, Stefanatos G, Sokolski K, et al: Improved social and language skills after secretin administration in patients with autism spectrum disorders. J Assoc Acad Minor Phys 9:9-15, 1998.
96. Owley T, Steele E, Corsello C, et al: A double-blind, placebo-controlled trial of secretin for the treatment of autistic disorder. MedGenMed October 6, 1999.
97. Sandler AD, Sutton KA, DeWeese J, et al: Lack of benefit of a single dose of synthetic human secretin in the treatment of autism and pervasive developmental disorders. N Engl J Med 341:1801-1806, 1999.
98. Dunn-Geier J, Ho HH, Auersperg E, et al: Effect of secretin on children with autism: A randomized controlled trial. Dev Med Child Neurol 42:796-802, 2000.
99. Roberts W, Weaver L, Brian J, et al: Repeated doses of porcine secretin in the treatment of autism: A randomized, placebo-control trial. Pediatrics 107:e71, 2001.
100. Unis AS, Munson JA, Rogers SJ, et al: A randomized, double-blind, placebo-controlled trial of porcine versus synthetic secretin for reducing symptoms of autism. J Am Acad Child Adolesc Psychiatry 41:1315-1321, 2002.
101. Nordin V, Gillberg C: Autism spectrum disorders in children with physical or mental disability or both: I. Clinical and epidemiological aspects. Dev Med Child Neurol 38:297-313, 1996.
102. Jure R, Rapin I, Tuchman RF: Hearing-impaired autistic children. Dev Med Child Neurol 33:1062-1072, 1991.
103. Rosenhall U, Nordin V, Sandstrom M, et al: Autism and hearing loss. J Autism Dev Disord 29:349-357, 1999.
104. Honomichl RD, Goodlin-Jones BL, Burnham M, et al: Sleep in patterns of children with pervasive developmental disorders. J Autism Dev Disord 32:553, 2002
105. Gabriels RL: Therapy: Laying the foundation for individual and family growth, in Gabriels RL, Hill DE (eds): Autism: From Research to Individual Practice. London, Jessica Kingsley, 2002, pp 91-126.
106. Lovaas OI: Behavioral treatment and normal educational and intellectual functioning in young autistic children. J Consult Clin Psychol 55:3-9, 1987.
107. McEachlin JJ, Smith T, Lovaas OI: Am J Ment Retard 97:359-372, 1993.
108. Grandin T: Thinking in Pictures. New York, Vantage Books, 1995.
109. Lindsay RL, Aman MG: Pharmacologic therapies aid treatment for autism. Pediatr Ann 32:671-676, 2003.
110. King BH: Pharmacological treatment of mood disturbances, aggression, and self-injury in persons with pervasive developmental disorders. J Autism Dev Disord 30:439-445, 2000.
111. Scahill L, for the Research Units on Pediatric Psychopharmacology Autism Network: Risperidone in children with autism and serious behavioural problems. N Engl J Med 347:314-321, 2002.
112. Malone RP, Maislen G, Choudhury MS, et al: Risperidone treatment in children and adolescents with autism: Short- and long-term safety and effectiveness. J Am Acad Child Adolesc Psychiatry 41:140-147, 2002.
113. Gilman JT, Tuchman RF: Autism and associated behavioral disorders: Pharmacotherapeutic intervention. Ann Pharmacother 29:47-56, 1995.
114. McDougle CJ, Kresch LE, Posey DJ: Repetitive thoughts and behavior in pervasive developmental disorders: Treatment with serotonin reuptake inhibitors. J Autism Dev Disord 30:427-435, 2000.
115. Gordon CT: Considerations on the pharmacological treatment of compulsions and stereotypes with serotonin reuptake inhibitors in pervasive developmental disorders (commentary). J Autism Dev Disord 30:437-438, 2000.
116. Aman MG, Langworthy KS: Pharmacotherapy for hyperactivity in children with autism and other pervasive developmental disorders. J Autism Dev Disord 30:451-457, 2000.
117. Campbell M, Anderson LT, Small AM, et al: Naltrexone in autistic children: Behavioral symptoms and attentional learning. J Am Acad Child Adolesc Psychiatry 32:1283-1291, 1993.
118. Kolmen B, Feldman HM, Handen BJ, et al: Naltrexone in young autistic children: A double-blind, placebo-controlled cross-over study. J Am Acad Child Adolesc Psychiatry 34:223-231, 1995.