Studies on the receptors mediating responses of osteoblasts to thrombin

International Journal of Biochemistry and Cell Biology

Volumn 37, Issue 1, 2005, Pages 206-213

  Song, S J ^a   Pagel, C N ^a   Pike, R N ^b   Mackie, E J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Differentiation; Osteoblast; Proliferation; Protease activated receptor; Thrombin

Indexed keywords

ALANYLTYROSYLPROLYLGLYCYLLYSYLPHENYLALANINAMIDE; ALKALINE PHOSPHATASE; BROXURIDINE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 4; SERINE PROTEINASE; SYNTHETIC PEPTIDE; THREONYLPHENYLALANYLPHENYLALANYLLEUCYLARGININAMIDE; THROMBIN; THROMBIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; MOUSE; NEWBORN; NONHUMAN; OSTEOBLAST; PROTEIN EXPRESSION; WILD TYPE;

RICKETTSIA SP. PAR;

EID: 4644222869     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2004.04.026     Document Type: Article

References (27)

1. L.A. Abraham, and E.J. Mackie Modulation of osteoblast-like Cell behavior by activation of protease-activated receptor-1 J. Bone Miner. Res. 14 1999 1320 1329
2. L.A. Abraham, C. Chinni, A.L. Jenkins, A. Lourbakos, N. Ally, and R.N. Pike Expression of protease-activated receptor-2 by osteoblasts Bone 26 2000 7 14
3. L.A. Abraham, A.L. Jenkins, S.R. Stone, and E.J. Mackie Expression of the thrombin receptor in developing bone and associated tissues J. Bone Miner. Res. 13 1998 818 827
4. I.A. Akers, M. Parsons, M.R. Hill, M.D. Hollenberg, S. Sanjar, and G.J. Laurent Mast cell tryptase stimulates human lung fibroblast proliferation via protease-activated receptor-2 Am. J. Physiol. Lung Cell. Mol. Physiol. 278 2000 193 201
5. C. Chinni, M.R. De Niese, A.L. Jenkins, R.N. Pike, S.P. Bottomley, and E.J. Mackie Protease-activated receptor-2 mediates proliferative responses in skeletal myoblasts J. Cell Sci. 113 Pt 24 2000 4427 4433
6. A.J. Connolly, H. Ishihara, M.L. Kahn, R.V. Farese Jr., and S.R. Coughlin Role of the thrombin receptor in development and evidence for a second receptor Nature 381 1996 516 519
7. S.R. Coughlin How the protease thrombin talks to cells Proc. Natl. Acad. Sci. U.S.A. 96 1999 11023 11027
8. T.R. Faruqi, E.J. Weiss, M.J. Shapiro, W. Huang, and S.R. Coughlin Structure-function analysis of protease-activated receptor 4 tethered ligand peptides. Determinants of specificity and utility in assays of receptor function J. Biol. Chem. 275 2000 19728 19734
9. N.R. Goldsack, R.C. Chambers, K. Dabbagh, and G.J. Laurent Thrombin Int. J. Biochem. Cell Biol. 30 1998 641 646
10. C.T. Griffin, Y. Srinivasan, Y.W. Zheng, W. Huang, and S.R. Coughlin A role for thrombin receptor signaling in endothelial cells during embryonic development Science 293 2001 1666 1670
11. M.D. Hollenberg, M. Saifeddine, B. Al-Ani, and A. Kawabata Proteinase-activated receptors: Structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides Can. J. Physiol. Pharmacol. 75 1997 832 841
12. H. Ishihara, A.J. Connolly, D. Zeng, M.L. Kahn, Y.W. Zheng, and C. Timmons Protease-activated receptor 3 is a second thrombin receptor in humans Nature 386 1997 502 506
13. A.L. Jenkins, M.D. Bootman, C.W. Taylor, E.J. Mackie, and S.R. Stone Characterization of the receptor responsible for thrombin-induced intracellular calcium responses in osteoblast-like cells J. Biol. Chem. 268 1993 21432 21437
14. M.L. Kahn, Y.W. Zheng, W. Huang, V. Bigornia, D. Zeng, and S. Moff A dual thrombin receptor system for platelet activation Nature 394 1998 690 694
15. A. Kawabata, M. Saifeddine, B. Al-Ani, and M.D. Hollenberg Protease-activated receptors: Development of agonists selective for receptors triggered by either thrombin (Par1) or trypsin (Par2) Proc. West Pharmacol. Soc. 40 1997 49 51
16. D.J. Lerner, M. Chen, T. Tram, and S.R. Coughlin Agonist recognition by proteinase-activated receptor 2 and thrombin receptor. Importance of extracellular loop interactions for receptor function J. Biol. Chem. 271 1996 13943 13947
17. S.R. Macfarlane, M.J. Seatter, T. Kanke, G.D. Hunter, and R. Plevin Proteinase-activated receptors Pharmacol. Rev. 53 2001 245 282
18. E.J. Mackie, C.N. Pagel, R. Smith, M.R. De Niese, S.J. Song, and R.N. Pike Protease-activated receptors: A means of converting extracellular proteolysis into intracellular signals IUBMB Life 53 2002 277 281
19. T.J. Martin, K.W. Ng, N.C. Partridge, and S.A. Livesey Hormonal influences on bone cells Methods Enzymol. 145 1987 324 336
20. M. Nakanishi-Matsui, Y.W. Zheng, D.J. Sulciner, E.J. Weiss, M.J. Ludeman, and S.R. Coughlin Par3 is a cofactor for Par4 activation by thrombin Nature 404 2000 609 613
21. C.N. Pagel, M.R. De Niese, L.A. Abraham, C. Chinni, S.J. Song, and R.N. Pike Inhibition of osteoblast apoptosis by thrombin Bone 33 2003 733 743
22. A. Sabri, J. Guo, H. Elouardighi, A.L. Darrow, P. Andrade-Gordon, and S.F. Steinberg Mechanisms of protease-activated receptor-4 actions in cardiomyocytes: Role of Src tyrosine kinase J. Biol. Chem. 278 2003 11714 11720
23. M.J. Shapiro, E.J. Weiss, T.R. Faruqi, and S.R. Coughlin Protease-activated receptor-1 and 4 are shut off with distinct kinetics after activation by thrombin J. Biol. Chem. 275 2000 25216 25221
24. S.R. Stone, and J. Hofsteenge Kinetics of the inhibition of thrombin by hirudin Biochemistry 25 1986 4622 4628
25. A. Suzuki, O. Kozawa, J. Shinoda, Y. Watanabe, H. Saito, and Y. Oiso Thrombin induces proliferation of osteoblast-like cells through phosphatidylcholine hydrolysis J. Cell Physiol. 168 1996 209 216
26. D.N. Tatakis, C. Dolce, and R. Dziak Thrombin's effects on osteoblastic cells. I. Cytosolic calcium and phosphoinositides Biochem. Biophys. Res. Commun. 164 1989 119 127
27. T.K. Vu, D.T. Hung, V.I. Wheaton, and S.R. Coughlin Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation Cell 64 1991 1057 1068