-
1
-
-
0037373275
-
Discovering genotypes underlying human phenotypes: Past successes for mendelian disease, future approaches for complex disease
-
Botstein D, Risch N: Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat Genet 2003;33(suppl):228-237.
-
(2003)
Nat Genet
, vol.33
, Issue.SUPPL.
, pp. 228-237
-
-
Botstein, D.1
Risch, N.2
-
2
-
-
0034791035
-
High-resolution haplotype structure in the human genome
-
Daly MJ, Rioux JD, Schaffner SF, Hudson TJ, Lander ES: High-resolution haplotype structure in the human genome. Nat Genet 2001;29:229-232.
-
(2001)
Nat Genet
, vol.29
, pp. 229-232
-
-
Daly, M.J.1
Rioux, J.D.2
Schaffner, S.F.3
Hudson, T.J.4
Lander, E.S.5
-
3
-
-
79959503826
-
The International HapMap Project
-
Consortium
-
Consortium: The International HapMap Project. Nature 2003;426:789-796.
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
4
-
-
79959524146
-
A haplotype map of the human genome
-
Altshuler D, Brooks LD, Chakravarti A, Collins FS, Daly MJ, Donnelly P: A haplotype map of the human genome. Nature 2005;437:1299-1320.
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
Altshuler, D.1
Brooks, L.D.2
Chakravarti, A.3
Collins, F.S.4
Daly, M.J.5
Donnelly, P.6
-
5
-
-
0344033602
-
Detecting disease associations due to linkage disequilibrium using haplotype tags: A class of tests and the determinants of statistical power
-
Chapman JM, Cooper JD, Todd JA, Clayton DG: Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power. Hum Hered 2003;56:18-31.
-
(2003)
Hum Hered
, vol.56
, pp. 18-31
-
-
Chapman, J.M.1
Cooper, J.D.2
Todd, J.A.3
Clayton, D.G.4
-
6
-
-
0346373654
-
Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium
-
Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA: Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 2004;74:106-120.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 106-120
-
-
Carlson, C.S.1
Eberle, M.A.2
Rieder, M.J.3
Yi, Q.4
Kruglyak, L.5
Nickerson, D.A.6
-
7
-
-
2142773942
-
The fine-scale structure of recombination rate variation in the human genome
-
McVean GA, Myers SR, Hunt S, Deloukas P, Bentley DR, Donnelly P: The fine-scale structure of recombination rate variation in the human genome. Science 2004;304:581-584.
-
(2004)
Science
, vol.304
, pp. 581-584
-
-
McVean, G.A.1
Myers, S.R.2
Hunt, S.3
Deloukas, P.4
Bentley, D.R.5
Donnelly, P.6
-
8
-
-
20144387806
-
Comparison of fine-scale recombination rates in humans and chimpanzees
-
Winckler W, Myers SR, Richter DJ, et al: Comparison of fine-scale recombination rates in humans and chimpanzees. Science 2005;308:107-111.
-
(2005)
Science
, vol.308
, pp. 107-111
-
-
Winckler, W.1
Myers, S.R.2
Richter, D.J.3
-
9
-
-
20044377420
-
Human recombination hot spots hidden in regions of strong marker association
-
Jeffreys AJ, Neumann R, Panayi M, Myers S, Donnelly P: Human recombination hot spots hidden in regions of strong marker association. Nat Genet 2005;37:601-606.
-
(2005)
Nat Genet
, vol.37
, pp. 601-606
-
-
Jeffreys, A.J.1
Neumann, R.2
Panayi, M.3
Myers, S.4
Donnelly, P.5
-
10
-
-
0034795550
-
Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex
-
Jeffreys AJ, Kauppi L, Neumann R: Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex. Nat Genet 2001;29:217-222.
-
(2001)
Nat Genet
, vol.29
, pp. 217-222
-
-
Jeffreys, A.J.1
Kauppi, L.2
Neumann, R.3
-
11
-
-
26444503776
-
Factors influencing recombination frequency and distribution in a human meiotic crossover hotspot
-
Jeffreys AJ, Neumann R: Factors influencing recombination frequency and distribution in a human meiotic crossover hotspot. Hum Mol Genet 2005;14:2277-2287.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2277-2287
-
-
Jeffreys, A.J.1
Neumann, R.2
-
12
-
-
0036649022
-
Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot
-
Jeffreys AJ, Neumann R: Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot. Nat Genet 2002;31:267-271.
-
(2002)
Nat Genet
, vol.31
, pp. 267-271
-
-
Jeffreys, A.J.1
Neumann, R.2
-
13
-
-
0037133218
-
The first linkage disequilibrium (LD) maps: Delineation of hot and cold blocks by diplotype analysis
-
Maniatis N, Collins A, Xu CF, et al: The first linkage disequilibrium (LD) maps: delineation of hot and cold blocks by diplotype analysis. Proc Natl Acad Sci USA 2002;99:2228-2233.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2228-2233
-
-
Maniatis, N.1
Collins, A.2
Xu, C.F.3
-
14
-
-
23844437267
-
A map of the human genome in linkage disequilibrium units
-
Tapper W, Collins A, Gibson J, Maniatis N, Ennis S, Morton NE: A map of the human genome in linkage disequilibrium units. Proc Natl Acad Sci USA 2005;102:11835-11839.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11835-11839
-
-
Tapper, W.1
Collins, A.2
Gibson, J.3
Maniatis, N.4
Ennis, S.5
Morton, N.E.6
-
15
-
-
11144242955
-
Impact of population structure, effective bottleneck time, and allele frequency on linkage disequilibrium maps
-
Zhang W, Collins A, Gibson J, et al: Impact of population structure, effective bottleneck time, and allele frequency on linkage disequilibrium maps. Proc Natl Acad Sci USA 2004;101:18075-18080.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 18075-18080
-
-
Zhang, W.1
Collins, A.2
Gibson, J.3
-
16
-
-
2342615572
-
Positional cloning by linkage disequilibrium
-
Maniatis N, Collins A, Gibson J, Zhang W, Tapper W, Morton NE: Positional cloning by linkage disequilibrium. Am J Hum Genet 2004;74:846-855.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 846-855
-
-
Maniatis, N.1
Collins, A.2
Gibson, J.3
Zhang, W.4
Tapper, W.5
Morton, N.E.6
-
17
-
-
12344333331
-
The optimal measure of linkage disequilibrium reduces error in association mapping of affection status
-
Maniatis N, Morton NE, Gibson J, Xu CF, Hosking LK, Collins A: The optimal measure of linkage disequilibrium reduces error in association mapping of affection status. Hum Mol Genet 2005;14:145-153.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 145-153
-
-
Maniatis, N.1
Morton, N.E.2
Gibson, J.3
Xu, C.F.4
Hosking, L.K.5
Collins, A.6
-
18
-
-
3543040619
-
Does haplotype diversity predict power for association mapping of disease susceptibility?
-
Zhang W, Collins A, Morton NE: Does haplotype diversity predict power for association mapping of disease susceptibility? Hum Genet 2004;115:157-164.
-
(2004)
Hum Genet
, vol.115
, pp. 157-164
-
-
Zhang, W.1
Collins, A.2
Morton, N.E.3
-
19
-
-
0037168588
-
Properties of linkage disequilibrium (LD) maps
-
Zhang W, Collins A, Maniatis N, Tapper W, Morton NE: Properties of linkage disequilibrium (LD) maps. Proc Natl Acad Sci USA 2002;99:17004-17007.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 17004-17007
-
-
Zhang, W.1
Collins, A.2
Maniatis, N.3
Tapper, W.4
Morton, N.E.5
-
20
-
-
20444366133
-
Localized breakdown in linkage disequilibrium does not always predict sperm crossover hot spots in the human MHC class II region
-
Kauppi L, Stumpf MP, Jeffreys AJ: Localized breakdown in linkage disequilibrium does not always predict sperm crossover hot spots in the human MHC class II region. Genomics 2005;86:13-24.
-
(2005)
Genomics
, vol.86
, pp. 13-24
-
-
Kauppi, L.1
Stumpf, M.P.2
Jeffreys, A.J.3
-
21
-
-
0032539537
-
Mapping a disease locus by allelic association
-
Collins A, Morton NE: Mapping a disease locus by allelic association. Proc Natl Acad Sci USA 1998;95:1741-1745.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1741-1745
-
-
Collins, A.1
Morton, N.E.2
-
22
-
-
7244245762
-
Finishing the euchromatic sequence of the human genome
-
Consortium
-
Consortium. Finishing the euchromatic sequence of the human genome. Nature 2004;431:931-945.
-
(2004)
Nature
, vol.431
, pp. 931-945
-
-
-
26
-
-
33645369422
-
Cosmopolitan linkage disequilibrium maps
-
Gibson J, Tapper W, Zhang W, Morton N, Collins A: Cosmopolitan linkage disequilibrium maps. Hum Genomics 2005;2:20-27.
-
(2005)
Hum Genomics
, vol.2
, pp. 20-27
-
-
Gibson, J.1
Tapper, W.2
Zhang, W.3
Morton, N.4
Collins, A.5
-
27
-
-
0016319012
-
Estimation of linkage disequilibrium in randomly mating populations
-
Hill WG: Estimation of linkage disequilibrium in randomly mating populations. Heredity 1974;33:229-239.
-
(1974)
Heredity
, vol.33
, pp. 229-239
-
-
Hill, W.G.1
-
28
-
-
8844280819
-
A combined linkage-physical map of the human genome
-
Kong X, Murphy K, Raj T, He C, White PS, Matise TC: A combined linkage-physical map of the human genome. Am J Hum Genet 2004;75:1143-1148.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 1143-1148
-
-
Kong, X.1
Murphy, K.2
Raj, T.3
He, C.4
White, P.S.5
Matise, T.C.6
-
29
-
-
0032133324
-
High-resolution mapping of crossovers in human sperm defines a minisatellite-associated recombination hotspot
-
Jeffreys AJ, Murray J, Neumann R: High-resolution mapping of crossovers in human sperm defines a minisatellite-associated recombination hotspot. Mol Cell 1998;2:267-273.
-
(1998)
Mol Cell
, vol.2
, pp. 267-273
-
-
Jeffreys, A.J.1
Murray, J.2
Neumann, R.3
-
30
-
-
0034701292
-
High resolution analysis of haplotype diversity and meiotic crossover in the human TAP2 recombination hotspot
-
Jeffreys AJ, Ritchie A, Neumann R: High resolution analysis of haplotype diversity and meiotic crossover in the human TAP2 recombination hotspot. Hum Mol Genet 2000;9:725-733.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 725-733
-
-
Jeffreys, A.J.1
Ritchie, A.2
Neumann, R.3
-
31
-
-
17144371712
-
The linkage disequilibrium maps of three human chromosomes across four populations reflect their demographic history and a common underlying recombination pattern
-
De La Vega, Isaac H, Collins A, et al: The linkage disequilibrium maps of three human chromosomes across four populations reflect their demographic history and a common underlying recombination pattern. Genome Res 2005;15:454-462.
-
(2005)
Genome Res
, vol.15
, pp. 454-462
-
-
La Vega, D.1
Isaac, H.2
Collins, A.3
-
32
-
-
16344392281
-
Absence of the TAP2 human recombination hotspot in chimpanzees
-
Ptak SE, Roeder AD, Stephens M, Gilad Y, Paabo S, Przeworski M: Absence of the TAP2 human recombination hotspot in chimpanzees. PLoS Biol 2004;2:e155.
-
(2004)
PLoS Biol
, vol.2
-
-
Ptak, S.E.1
Roeder, A.D.2
Stephens, M.3
Gilad, Y.4
Paabo, S.5
Przeworski, M.6
-
33
-
-
16844377748
-
Fine-scale recombination patterns differ between chimpanzees and humans
-
Ptak SE, Hinds DA, Koehler K, et al: Fine-scale recombination patterns differ between chimpanzees and humans. Nat Genet 2005;37:429-434.
-
(2005)
Nat Genet
, vol.37
, pp. 429-434
-
-
Ptak, S.E.1
Hinds, D.A.2
Koehler, K.3
-
34
-
-
20144387806
-
Comparison of fine-scale recombination rates in humans and chimpanzees
-
Winckler W, Myers SR, Richter DJ, et al: Comparison of fine-scale recombination rates in humans and chimpanzees. Science 2005;308:107-111.
-
(2005)
Science
, vol.308
, pp. 107-111
-
-
Winckler, W.1
Myers, S.R.2
Richter, D.J.3
-
35
-
-
33646130166
-
Polymorphism in the activity of human crossover hotspots independent of local DNA sequence variation
-
Neumann R, Jeffreys AJ: Polymorphism in the activity of human crossover hotspots independent of local DNA sequence variation. Hum Mol Genet 2006;15:1401-1411.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1401-1411
-
-
Neumann, R.1
Jeffreys, A.J.2
-
36
-
-
0031025043
-
Characterization of recombination in the HLA class II region
-
Cullen M, Noble J, Erlich H, et al: Characterization of recombination in the HLA class II region. Am J Hum Genet 1997;60:397-407.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 397-407
-
-
Cullen, M.1
Noble, J.2
Erlich, H.3
|