-
1
-
-
0026753155
-
Beneficial health effects of modest weight loss
-
Goldstein DJ. Beneficial health effects of modest weight loss. Int J Obes Relat Metab Disord 1992;16:397-415.
-
(1992)
Int J Obes Relat Metab Disord
, vol.16
, pp. 397-415
-
-
Goldstein, D.J.1
-
2
-
-
15544370296
-
Long-term pharmacotherapy for obesity
-
Klein S. Long-term pharmacotherapy for obesity. Obes Res 2004;12(Suppl):163S-166S.
-
(2004)
Obes Res
, vol.12
, Issue.SUPPL.
-
-
Klein, S.1
-
3
-
-
29944438889
-
Pharmacotherapy for obesity
-
Halford JC. Pharmacotherapy for obesity. Appetite 2006;46:6-10.
-
(2006)
Appetite
, vol.46
, pp. 6-10
-
-
Halford, J.C.1
-
4
-
-
0034067633
-
Behavioral treatment of obesity
-
vii
-
Wadden TA, Foster GD. Behavioral treatment of obesity. Med Clin North Am 2000;84:441-61, vii.
-
(2000)
Med Clin North Am
, vol.84
, pp. 441-461
-
-
Wadden, T.A.1
Foster, G.D.2
-
5
-
-
0019944850
-
Neuropeptide Y - a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide
-
Tatemoto K, Carlquist M, Mutt V. Neuropeptide Y - a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide. Nature 1982;296:659-660.
-
(1982)
Nature
, vol.296
, pp. 659-660
-
-
Tatemoto, K.1
Carlquist, M.2
Mutt, V.3
-
6
-
-
0037066612
-
Neuropeptide Y receptors as targets for anti-obesity drug development: Perspective and current status
-
Parker E, Van Heek M, Stamford A. Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status. Eur J Pharmacol 2002;440:173-187.
-
(2002)
Eur J Pharmacol
, vol.440
, pp. 173-187
-
-
Parker, E.1
Van Heek, M.2
Stamford, A.3
-
7
-
-
15844420659
-
A receptor subtype involved in neuropeptide-Y-induced food intake
-
Gerald C, Walker MW, Criscione L et al. A receptor subtype involved in neuropeptide-Y-induced food intake. Nature 1996;382:168-171.
-
(1996)
Nature
, vol.382
, pp. 168-171
-
-
Gerald, C.1
Walker, M.W.2
Criscione, L.3
-
8
-
-
0034858816
-
Identification of potent and selective neuropeptide Y Y(1) receptor agonists with orexigenic activity in vivo
-
Mullins D, Kirby D, Hwa J et al. Identification of potent and selective neuropeptide Y Y(1) receptor agonists with orexigenic activity in vivo. Mol Pharmacol 2001;60:534-540.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 534-540
-
-
Mullins, D.1
Kirby, D.2
Hwa, J.3
-
9
-
-
0038748202
-
Characterization of neuropeptide Y (NPY) Y5 receptor-mediated obesity in mice: Chronic intracerebroventricular infusion of D-Trp(34)NPY
-
Mashiko S, Ishihara A, Iwaasa H et al. Characterization of neuropeptide Y (NPY) Y5 receptor-mediated obesity in mice: chronic intracerebroventricular infusion of D-Trp(34)NPY. Endocrinology 2003;144:1793-1801.
-
(2003)
Endocrinology
, vol.144
, pp. 1793-1801
-
-
Mashiko, S.1
Ishihara, A.2
Iwaasa, H.3
-
10
-
-
20644442223
-
Energy metabolic profile of mice after chronic activation of central NPY Y1, Y2, or Y5 receptors
-
Henry M, Ghibaudi L, Gao J, Hwa JJ. Energy metabolic profile of mice after chronic activation of central NPY Y1, Y2, or Y5 receptors. Obes Res. 2005;13:36-47.
-
(2005)
Obes Res
, vol.13
, pp. 36-47
-
-
Henry, M.1
Ghibaudi, L.2
Gao, J.3
Hwa, J.J.4
-
11
-
-
0037043704
-
Gut hormone PYY(3-36) physiologically inhibits food intake
-
Batterham RL, Cowley MA, Small CJ et al. Gut hormone PYY(3-36) physiologically inhibits food intake. Nature 2002;418:650-654.
-
(2002)
Nature
, vol.418
, pp. 650-654
-
-
Batterham, R.L.1
Cowley, M.A.2
Small, C.J.3
-
12
-
-
33646482230
-
A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice
-
Ishihara A, Kanatani A, Mashiko S et al. A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice. Proc Natl Acad Sci USA 2006;103:7154-7158.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7154-7158
-
-
Ishihara, A.1
Kanatani, A.2
Mashiko, S.3
-
14
-
-
0032535371
-
Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor
-
Criscione L, Rigollier P, Batzl-Hartmann C et al. Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor. J Clin Invest 1998;102:2136-2145.
-
(1998)
J Clin Invest
, vol.102
, pp. 2136-2145
-
-
Criscione, L.1
Rigollier, P.2
Batzl-Hartmann, C.3
-
15
-
-
0037096146
-
Food intake inhibition and reduction in body weight gain in lean and obese rodents treated with GW438014A, a potent and selective NPY-Y5 receptor antagonist
-
Daniels AJ, Grizzle MK, Wiard RP, Matthews JE, Heyer D. Food intake inhibition and reduction in body weight gain in lean and obese rodents treated with GW438014A, a potent and selective NPY-Y5 receptor antagonist. Regul Pept 2002;106:47-54.
-
(2002)
Regul Pept
, vol.106
, pp. 47-54
-
-
Daniels, A.J.1
Grizzle, M.K.2
Wiard, R.P.3
Matthews, J.E.4
Heyer, D.5
-
16
-
-
0036320829
-
Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats
-
Turnbull AV, Ellershaw L, Masters DJ et al. Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats. Diabetes 2002;51:2441-2449.
-
(2002)
Diabetes
, vol.51
, pp. 2441-2449
-
-
Turnbull, A.V.1
Ellershaw, L.2
Masters, D.J.3
-
17
-
-
8944263303
-
Cloning and expression of a novel neuropeptide Y receptor
-
Weinberg DH, Sirinathsinghji DJ, Tan CP et al. Cloning and expression of a novel neuropeptide Y receptor. J Biol Chem 1996;271:16435-16438.
-
(1996)
J Biol Chem
, vol.271
, pp. 16435-16438
-
-
Weinberg, D.H.1
Sirinathsinghji, D.J.2
Tan, C.P.3
-
18
-
-
0024600842
-
Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor-1 alpha
-
Uetsuki T, Naito A, Nagata S, Kaziro Y. Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor-1 alpha. J Biol Chem 1989;264:5791-5798.
-
(1989)
J Biol Chem
, vol.264
, pp. 5791-5798
-
-
Uetsuki, T.1
Naito, A.2
Nagata, S.3
Kaziro, Y.4
-
19
-
-
12144286708
-
Role of the Y1 receptor in the regulation of neuropeptide Y-mediated feeding: Comparison of wild-type, Y1 receptor-deficient, and Y5 receptor-deficient mice
-
Kanatani A, Mashiko S, Murai N et al. Role of the Y1 receptor in the regulation of neuropeptide Y-mediated feeding: comparison of wild-type, Y1 receptor-deficient, and Y5 receptor-deficient mice. Endocrinology 2000;141:1011-1016.
-
(2000)
Endocrinology
, vol.141
, pp. 1011-1016
-
-
Kanatani, A.1
Mashiko, S.2
Murai, N.3
-
20
-
-
33846406036
-
A pair-feeding study reveals that a Y5 antagonist causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure
-
Mashiko S, Ishihara A, Iwaasa H et al. A pair-feeding study reveals that a Y5 antagonist causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure. Mol Pharmacol 2006;71:602-608.
-
(2006)
Mol Pharmacol
, vol.71
, pp. 602-608
-
-
Mashiko, S.1
Ishihara, A.2
Iwaasa, H.3
-
21
-
-
0035142565
-
Synergistic effects of opioid and cannabinoid antagonists on food intake
-
Kirkham TC, Williams CM. Synergistic effects of opioid and cannabinoid antagonists on food intake. Psychopharmacology (Berl) 2001;153:267-270.
-
(2001)
Psychopharmacology (Berl)
, vol.153
, pp. 267-270
-
-
Kirkham, T.C.1
Williams, C.M.2
-
22
-
-
0030931678
-
Synergistic interaction between leptin and cholecystokinin to reduce short-term food intake in lean mice
-
Barrachina MD, Martinez V, Wang L, Wei JY, Tache Y. Synergistic interaction between leptin and cholecystokinin to reduce short-term food intake in lean mice. Proc Natl Acad Sci USA 1997;94:10455-10460.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10455-10460
-
-
Barrachina, M.D.1
Martinez, V.2
Wang, L.3
Wei, J.Y.4
Tache, Y.5
-
23
-
-
23844554610
-
Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice
-
Talsania T, Anini Y, Siu S, Drucker DJ, Brubaker PL. Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice. Endocrinology 2005;146:3748-3756.
-
(2005)
Endocrinology
, vol.146
, pp. 3748-3756
-
-
Talsania, T.1
Anini, Y.2
Siu, S.3
Drucker, D.J.4
Brubaker, P.L.5
-
24
-
-
13844321589
-
Efficacy of sibutramine, orlistat and combination therapy on short-term weight management in obese patients
-
Kaya A, Aydin N, Topsever P et al. Efficacy of sibutramine, orlistat and combination therapy on short-term weight management in obese patients. Biomed Pharmacother 2004;58:582-587.
-
(2004)
Biomed Pharmacother
, vol.58
, pp. 582-587
-
-
Kaya, A.1
Aydin, N.2
Topsever, P.3
-
25
-
-
0034264256
-
Effects of sibutramine plus orlistat in obese women following 1 year of treatment by sibutramine alone: A placebo-controlled trial
-
Wadden TA, Berkowitz RI, Womble LG et al. Effects of sibutramine plus orlistat in obese women following 1 year of treatment by sibutramine alone: a placebo-controlled trial. Obes Res 2000;8:431-437.
-
(2000)
Obes Res
, vol.8
, pp. 431-437
-
-
Wadden, T.A.1
Berkowitz, R.I.2
Womble, L.G.3
-
26
-
-
0026517115
-
Long-term weight control: The National Heart, Lung, and Blood Institute funded multimodal intervention study
-
Weintraub M. Long-term weight control: the National Heart, Lung, and Blood Institute funded multimodal intervention study. Clin Pharmacol Ther 1992;51:581-585.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 581-585
-
-
Weintraub, M.1
-
27
-
-
0030876952
-
Valvular heart disease associated with fenfluramine-phentermine
-
Connolly HM, Crary JL, McGoon MD et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med 1997;337:581-588.
-
(1997)
N Engl J Med
, vol.337
, pp. 581-588
-
-
Connolly, H.M.1
Crary, J.L.2
McGoon, M.D.3
-
28
-
-
0037066583
-
The discovery and status of sibutramine as an anti-obesity drug
-
Luque CA, Rey JA. The discovery and status of sibutramine as an anti-obesity drug. Eur J Pharmacol 2002;440:119-128.
-
(2002)
Eur J Pharmacol
, vol.440
, pp. 119-128
-
-
Luque, C.A.1
Rey, J.A.2
-
29
-
-
33748920715
-
Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults
-
Erondu N, Gantz I, Musser B et al. Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults. Cell Metab 2006;4:275-282.
-
(2006)
Cell Metab
, vol.4
, pp. 275-282
-
-
Erondu, N.1
Gantz, I.2
Musser, B.3
-
30
-
-
34548618969
-
NPY5R antagonism does not augment the weight loss efficacy of orlistat or sibutramine
-
Erondu N, Addy C, Lu K et al. NPY5R antagonism does not augment the weight loss efficacy of orlistat or sibutramine. Obesity (Silver Spring) 2007;15:2027-2042.
-
(2007)
Obesity (Silver Spring)
, vol.15
, pp. 2027-2042
-
-
Erondu, N.1
Addy, C.2
Lu, K.3
|