A pair-feeding study reveals that a Y5 antagonist causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure

Molecular Pharmacology

Volumn 71, Issue 2, 2007, Pages 602-608

  Mashiko, Satoshi ^a   Ishihara, Akane ^a   Iwaasa, Hisashi ^a   Sano, Hideki ^a   Ito, Junko ^a   Gomori, Akira ^a   Oda, Zenjun ^a   Moriya, Ryuichi ^a   Matsushita, Hiroko ^a   Jitsuoka, Makoto ^a   Okamoto, Osamu ^a   MacNeil, Douglas J ^b   Van Der Ploeg, Lex H T ^b   Fukami, Takehiro ^a   Kanatani, Akio ^a  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,3 DIMETHYL 9 (4,4 DIMETHYL 2,6 DIOXOCYCLOHEXYL) 1 OXO 1,2,3,4 TETRAHYDROXANTHENE; GLUCOSE; INSULIN; LEPTIN; LIVER TRIACYLGLYCEROL LIPASE; MESSENGER RNA; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y5 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DIET; DRUG MECHANISM; ENERGY EXPENDITURE; FEEDING; FOOD INTAKE; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; MALE; MOTOR ACTIVITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RECTUM TEMPERATURE; THERMOGENESIS; WEIGHT REDUCTION; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE; ANIMALS; BODY TEMPERATURE; DIET; EATING; ENERGY INTAKE; ENERGY METABOLISM; ION CHANNELS; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIAL PROTEINS; OBESITY; RECEPTORS, NEUROPEPTIDE Y; UP-REGULATION; WEIGHT LOSS;

EID: 33846406036     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.029991     Document Type: Article

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