Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin

Experimental Lung Research

Volumn 34, Issue 5, 2008, Pages 225-243

  Smith, Lincoln S ^a   Kajikawa, Osamu ^b   Elson, Greg ^c   Wick, Merry ^b   Mongovin, Steve ^b   Kosco Vilbois, Marie ^c   Martin, Thomas R ^a   Frevert, Charles W ^a,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b VA Puget Sound Medical Center   (United States)

^c NOVIMMUNE SA   (Switzerland)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Acute lung injury; Antibody blockade; CD14; Inflammation; Innate immunity; Lipopolysaccharide; Mechanical ventilation; TLR4; Toll like receptor 4; Ventilator induced lung injury

Indexed keywords

CD14 ANTIGEN; CD14 MONOCLONAL ANTIBODY; ENDOTOXIN; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 4 ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; BRACHYTHERAPY; CELL COUNT; CONTROLLED STUDY; FEMALE; LUNG LAVAGE; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; ANTIGENS, CD14; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; ESCHERICHIA COLI; FEMALE; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; LUNG; NEUTROPHILS; RABBITS; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; SPECIFIC PATHOGEN-FREE ORGANISMS; TOLL-LIKE RECEPTOR 4;

EID: 45849125820     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.1080/01902140802022492     Document Type: Article

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