-
1
-
-
33646107369
-
VEGF receptor signalling - in control of vascular function
-
Olsson, AK, Dimberg, A, Kreuger, J and Claesson-Welsh, L (2006). VEGF receptor signalling - in control of vascular function. Nat Rev Mol Cell Biol 7: 359-371.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 359-371
-
-
Olsson, A.K.1
Dimberg, A.2
Kreuger, J.3
Claesson-Welsh, L.4
-
2
-
-
33344474964
-
Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis
-
Shibuya, M and Claesson-Welsh, L (2006). Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis. Exp Cell Res 312: 549-560.
-
(2006)
Exp Cell Res
, vol.312
, pp. 549-560
-
-
Shibuya, M.1
Claesson-Welsh, L.2
-
3
-
-
2342445936
-
Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development
-
Magnusson, P, Rolny, C, Jakobsson, L, Wikner, C, Wu, Y, Hicklin, DJ et al. (2004). Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development. J Cell Sci 117: 1513-1523.
-
(2004)
J Cell Sci
, vol.117
, pp. 1513-1523
-
-
Magnusson, P.1
Rolny, C.2
Jakobsson, L.3
Wikner, C.4
Wu, Y.5
Hicklin, D.J.6
-
4
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet, P, Ferreira, V, Breier, G, Pollefeyt, S, Kieckens, L, Gertsenstein, M et al. (1996). Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380: 435-439.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
-
5
-
-
7144264398
-
Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice
-
Detmar, M, Brown, LF, Schon, MP, Elicker, BM, Velasco, P, Richard, L et al. (1998). Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice. J Invest Dermatol 111: 1-6.
-
(1998)
J Invest Dermatol
, vol.111
, pp. 1-6
-
-
Detmar, M.1
Brown, L.F.2
Schon, M.P.3
Elicker, B.M.4
Velasco, P.5
Richard, L.6
-
6
-
-
0031053759
-
Biological roles of fibroblast growth factor-2
-
Bikfalvi, A, Klein, S, Pintucci, G and Rifkin, DB (1997). Biological roles of fibroblast growth factor-2. Endocr Rev 18: 26-45.
-
(1997)
Endocr Rev
, vol.18
, pp. 26-45
-
-
Bikfalvi, A.1
Klein, S.2
Pintucci, G.3
Rifkin, D.B.4
-
7
-
-
0034721640
-
Maintenance of vascular integrity in the embryo requires signaling through the fibroblast growth factor receptor
-
Lee, SH, Schloss, DJ, and Swain, JL (2000). Maintenance of vascular integrity in the embryo requires signaling through the fibroblast growth factor receptor. J Biol Chem 275: 33679-33687.
-
(2000)
J Biol Chem
, vol.275
, pp. 33679-33687
-
-
Lee, S.H.1
Schloss, D.J.2
Swain, J.L.3
-
8
-
-
0037133306
-
Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2: Double-blind, randomized, controlled clinical trial
-
Simons, M, Annex, BH, Laham, RJ, Kleiman, N, Henry, T, Dauerman, H et al. (2002). Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2: Double-blind, randomized, controlled clinical trial. Circulation 105: 788-793.
-
(2002)
Circulation
, vol.105
, pp. 788-793
-
-
Simons, M.1
Annex, B.H.2
Laham, R.J.3
Kleiman, N.4
Henry, T.5
Dauerman, H.6
-
9
-
-
0037453099
-
The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis
-
Henry, TD, Annex, BH, McKendall, GR, Azrin, MA, Lopez, JJ, Giordano, FJ et al. (2003). The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis. Circulation 107 1359-1365.
-
(2003)
Circulation
, vol.107
, pp. 1359-1365
-
-
Henry, T.D.1
Annex, B.H.2
McKendall, G.R.3
Azrin, M.A.4
Lopez, J.J.5
Giordano, F.J.6
-
10
-
-
0037097035
-
Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): A randomised trial
-
Lederman, RJ, Mendelsohn, FO, Anderson, RD, Saucedo, JF, Tenaglia, AN, Hermiller, JB et al. (2002). Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): A randomised trial. Lancet 359: 2053-2058.
-
(2002)
Lancet
, vol.359
, pp. 2053-2058
-
-
Lederman, R.J.1
Mendelsohn, F.O.2
Anderson, R.D.3
Saucedo, J.F.4
Tenaglia, A.N.5
Hermiller, J.B.6
-
11
-
-
0027053487
-
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
-
Pepper, MS, Ferrara, N, Orci, L and Montesano, R (1992). Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Commun 189: 824-831.
-
(1992)
Biochem Biophys Res Commun
, vol.189
, pp. 824-831
-
-
Pepper, M.S.1
Ferrara, N.2
Orci, L.3
Montesano, R.4
-
12
-
-
0028827625
-
Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
-
Asahara, T, Bauters, C, Zheng, LP, Takeshita, S, Bunting, S, Ferrara, N et al. (1995). Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo. Circulation 92: II365-II371.
-
(1995)
Circulation
, vol.92
-
-
Asahara, T.1
Bauters, C.2
Zheng, L.P.3
Takeshita, S.4
Bunting, S.5
Ferrara, N.6
-
13
-
-
24944534593
-
VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRbeta signaling
-
Kano, MR, Morishita, Y, Iwata, C, Iwasaka, S, Watabe, T, Ouchi, Y et al. (2005). VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRbeta signaling. J Cell Sci 118: 3759-3768.
-
(2005)
J Cell Sci
, vol.118
, pp. 3759-3768
-
-
Kano, M.R.1
Morishita, Y.2
Iwata, C.3
Iwasaka, S.4
Watabe, T.5
Ouchi, Y.6
-
14
-
-
0034760458
-
Polymeric system for dual growth factor delivery
-
Richardson, TP, Peters, MC, Ennett, AB and Mooney, DJ (2001). Polymeric system for dual growth factor delivery. Nat Biotechnol 19: 1029-1034.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 1029-1034
-
-
Richardson, T.P.1
Peters, M.C.2
Ennett, A.B.3
Mooney, D.J.4
-
15
-
-
0038363443
-
Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2
-
Cao, R, Brakenhielm, E, Pawliuk, R, Wariaro, D, Post, MJ, Wahlberg, E et al. (2003). Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2. Nat Med 9: 604-613.
-
(2003)
Nat Med
, vol.9
, pp. 604-613
-
-
Cao, R.1
Brakenhielm, E.2
Pawliuk, R.3
Wariaro, D.4
Post, M.J.5
Wahlberg, E.6
-
16
-
-
4644318828
-
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
-
Appelhoff, RJ, Tian, YM, Raval, RR, Turley, H, Harris, AL, Pugh, CW et al. (2004). Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. J Biol Chem 279: 38458-38465.
-
(2004)
J Biol Chem
, vol.279
, pp. 38458-38465
-
-
Appelhoff, R.J.1
Tian, Y.M.2
Raval, R.R.3
Turley, H.4
Harris, A.L.5
Pugh, C.W.6
-
17
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza, GL (2003). Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
18
-
-
0035476509
-
Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1a
-
Elson, DA, Thurston, G, Huang, LE, Ginzinger, DG, McDonald, DM, Johnson, RS et al. (2001). Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1a. Genes Dev 15: 2520-2532.
-
(2001)
Genes Dev
, vol.15
, pp. 2520-2532
-
-
Elson, D.A.1
Thurston, G.2
Huang, L.E.3
Ginzinger, D.G.4
McDonald, D.M.5
Johnson, R.S.6
-
19
-
-
0344874751
-
Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1
-
Kelly, BD, Hackett, SF, Hirota, K, Oshima, Y, Cai, Z, Berg-Dixon, S et al. (2003). Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1. Circ Res 93: 1074-1081.
-
(2003)
Circ Res
, vol.93
, pp. 1074-1081
-
-
Kelly, B.D.1
Hackett, S.F.2
Hirota, K.3
Oshima, Y.4
Cai, Z.5
Berg-Dixon, S.6
-
20
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire, A, Xu, S, Montgomery, MK, Kostas, SA, Driver, SE and Mello, CC (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
21
-
-
4644350944
-
Unlocking the potential of the human genome with RNA interference
-
Hannon, GJ and Rossi, JJ (2004). Unlocking the potential of the human genome with RNA interference. Nature 431: 371-378.
-
(2004)
Nature
, vol.431
, pp. 371-378
-
-
Hannon, G.J.1
Rossi, J.J.2
-
22
-
-
12144288006
-
A resource for large-scale RNA-interference-based screens in mammals
-
Paddison, PJ, Silva, JM, Conklin, DS, Schlabach, M, Li, M, Aruleba, S et al. (2004). A resource for large-scale RNA-interference-based screens in mammals. Nature 428: 427-431.
-
(2004)
Nature
, vol.428
, pp. 427-431
-
-
Paddison, P.J.1
Silva, J.M.2
Conklin, D.S.3
Schlabach, M.4
Li, M.5
Aruleba, S.6
-
23
-
-
21344457432
-
RNA interference: From gene silencing to gene-specific therapeutics
-
Leung, RK and Whittaker, PA (2005). RNA interference: From gene silencing to gene-specific therapeutics. Pharmacol Ther 107: 222-239.
-
(2005)
Pharmacol Ther
, vol.107
, pp. 222-239
-
-
Leung, R.K.1
Whittaker, P.A.2
-
24
-
-
33645500266
-
Progress towards in vivo use of siRNAs
-
Behlke, MA (2006). Progress towards in vivo use of siRNAs. Mol Ther 13: 644-670.
-
(2006)
Mol Ther
, vol.13
, pp. 644-670
-
-
Behlke, M.A.1
-
25
-
-
33847615147
-
Prolyl hydroxylase domain 2 protein suppresses hypoxia-induced endothelial cell proliferation
-
Takeda, K and Fong, GH (2007). Prolyl hydroxylase domain 2 protein suppresses hypoxia-induced endothelial cell proliferation. Hypertension 49: 178-184.
-
(2007)
Hypertension
, vol.49
, pp. 178-184
-
-
Takeda, K.1
Fong, G.H.2
-
26
-
-
22244467409
-
Hypoxia-inducible factor 1α is a new target of microphthalmia-associated transcription factor (MITF) in melanoma cells
-
Busca, R, Berra, E, Gaggioli, C, Khaled, M, Bille, K, Marchetti, B et al. (2005). Hypoxia-inducible factor 1α is a new target of microphthalmia-associated transcription factor (MITF) in melanoma cells. J Cell Biol 170: 49-59.
-
(2005)
J Cell Biol
, vol.170
, pp. 49-59
-
-
Busca, R.1
Berra, E.2
Gaggioli, C.3
Khaled, M.4
Bille, K.5
Marchetti, B.6
-
27
-
-
0041465022
-
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia
-
Berra, E, Benizri, E, Ginouves, A, Volmat, V, Roux, D and Pouyssegur, J (2003). HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia. EMBO J 22: 4082-4090.
-
(2003)
EMBO J
, vol.22
, pp. 4082-4090
-
-
Berra, E.1
Benizri, E.2
Ginouves, A.3
Volmat, V.4
Roux, D.5
Pouyssegur, J.6
-
28
-
-
33646237345
-
Stable RNA interference: Comparison of U6 and H1 promoters in endothelial cells and in mouse brain
-
Makinen, PI, Koponen, JK, Karkkainen, AM, Malm, TM, Pulkkinen, KH, Koistinaho, J et al. (2006). Stable RNA interference: Comparison of U6 and H1 promoters in endothelial cells and in mouse brain. J Gene Med 8: 433-441.
-
(2006)
J Gene Med
, vol.8
, pp. 433-441
-
-
Makinen, P.I.1
Koponen, J.K.2
Karkkainen, A.M.3
Malm, T.M.4
Pulkkinen, K.H.5
Koistinaho, J.6
-
29
-
-
0014387089
-
Small molecular weight monodisperse nuclear RNA
-
Weinberg, RA and Penman, S (1968). Small molecular weight monodisperse nuclear RNA. J Mol Biol 38: 289-304.
-
(1968)
J Mol Biol
, vol.38
, pp. 289-304
-
-
Weinberg, R.A.1
Penman, S.2
-
30
-
-
33644837102
-
Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury
-
Natarajan, R, Salloum, FN, Fisher, BJ, Kukreja, RC and Fowler, AA 3rd (2006). Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury. Circ Res 98: 133-140.
-
(2006)
Circ Res
, vol.98
, pp. 133-140
-
-
Natarajan, R.1
Salloum, F.N.2
Fisher, B.J.3
Kukreja, R.C.4
Fowler 3rd, A.A.5
-
31
-
-
34547905406
-
Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system
-
Takeda, K, Cowan, A and Fong, GH (2007). Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system. Circulation 116: 774-781.
-
(2007)
Circulation
, vol.116
, pp. 774-781
-
-
Takeda, K.1
Cowan, A.2
Fong, G.H.3
-
32
-
-
0034702905
-
VEGF gene delivery to myocardium: Deleterious effects of unregulated expression
-
Lee, RJ, Springer, ML, Blanco-Bose, WE, Shaw, R, Ursell, PC and Blau, HM (2000). VEGF gene delivery to myocardium: Deleterious effects of unregulated expression. Circulation 102: 898-901.
-
(2000)
Circulation
, vol.102
, pp. 898-901
-
-
Lee, R.J.1
Springer, M.L.2
Blanco-Bose, W.E.3
Shaw, R.4
Ursell, P.C.5
Blau, H.M.6
-
33
-
-
33644533818
-
Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1α variant for local induction of angiogenesis
-
Trentin, D, Hall, H, Wechsler, S and Hubbell, JA (2006). Peptide-matrix-mediated gene transfer of an oxygen-insensitive hypoxia-inducible factor-1α variant for local induction of angiogenesis. Proc Natl Acad Sci USA 103: 2506-2511.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2506-2511
-
-
Trentin, D.1
Hall, H.2
Wechsler, S.3
Hubbell, J.A.4
-
34
-
-
16244377103
-
A crucial test
-
Check, E (2005). A crucial test. Nat Med 11: 243-244.
-
(2005)
Nat Med
, vol.11
, pp. 243-244
-
-
Check, E.1
-
35
-
-
13444262170
-
Inhibition of respiratory viruses by nasally administered siRNA
-
Bitko, V, Musiyenko, A, Shulyayeva, O and Barik, S (2005). Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 11 50-55.
-
(2005)
Nat Med
, vol.11
, pp. 50-55
-
-
Bitko, V.1
Musiyenko, A.2
Shulyayeva, O.3
Barik, S.4
-
36
-
-
33847036990
-
Strategies for silencing human disease using RNA interference
-
Kim, DH and Rossi, JJ (2007). Strategies for silencing human disease using RNA interference. Nat Rev Genet 8: 173-184.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 173-184
-
-
Kim, D.H.1
Rossi, J.J.2
-
38
-
-
33645165026
-
Viral-based modelling and correction of neurodegenerative diseases by RNA interference
-
Raoul, C, Barker, SO and Aebischer, P (2006). Viral-based modelling and correction of neurodegenerative diseases by RNA interference. Gene Ther 13: 487-495.
-
(2006)
Gene Ther
, vol.13
, pp. 487-495
-
-
Raoul, C.1
Barker, S.O.2
Aebischer, P.3
-
39
-
-
1542306939
-
Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression
-
Miyata, K, Kakizawa, Y, Nishiyama, N, Harada, A, Yamasaki, Y, Koyama, H et al. (2004). Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression. J Am Chem Soc 126: 2355-2361.
-
(2004)
J Am Chem Soc
, vol.126
, pp. 2355-2361
-
-
Miyata, K.1
Kakizawa, Y.2
Nishiyama, N.3
Harada, A.4
Yamasaki, Y.5
Koyama, H.6
-
40
-
-
33749578243
-
-
Kanayama, N, Fukushima, 5, Nishiyama, N, Itaka, K, Jang, WD, Mlyata, K et al. (2006). A PEG-based biocompatible block catiomer with high buffering capacity for the construction of polyplex micelles showing efficient gene transfer toward primary cells. ChemMedChem 1: 439-444.
-
Kanayama, N, Fukushima, 5, Nishiyama, N, Itaka, K, Jang, WD, Mlyata, K et al. (2006). A PEG-based biocompatible block catiomer with high buffering capacity for the construction of polyplex micelles showing efficient gene transfer toward primary cells. ChemMedChem 1: 439-444.
-
-
-
-
41
-
-
13644254495
-
Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells
-
Oishi, M, Nagasaki, Y, Itaka, K, Nishiyama, N and Kataoka, K (2005). Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells. J Am Chem Soc 127: 1624-1625.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 1624-1625
-
-
Oishi, M.1
Nagasaki, Y.2
Itaka, K.3
Nishiyama, N.4
Kataoka, K.5
-
42
-
-
33645241767
-
Organic-inorganic hybrid-nanocarrier of siRNA constructing through the self-assembly of calcium phosphate and PEG-based block aniomer
-
Kakizawa, Y, Furukawa, S, Ishii, A and Kataoka, K (2006). Organic-inorganic hybrid-nanocarrier of siRNA constructing through the self-assembly of calcium phosphate and PEG-based block aniomer. J Control Release 111: 368-370.
-
(2006)
J Control Release
, vol.111
, pp. 368-370
-
-
Kakizawa, Y.1
Furukawa, S.2
Ishii, A.3
Kataoka, K.4
-
43
-
-
34250770499
-
Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation
-
Akagi, D, Oba, M, Koyama, H, Nishiyama, N, Fukushima, S, Miyata, T et al. (2007). Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation. Gene Ther 14: 1029-1038.
-
(2007)
Gene Ther
, vol.14
, pp. 1029-1038
-
-
Akagi, D.1
Oba, M.2
Koyama, H.3
Nishiyama, N.4
Fukushima, S.5
Miyata, T.6
-
44
-
-
34548065400
-
Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles
-
Itaka, K, Ohba, S, Miyata, K, Kawaguchi, H, Nakamura, K, Takato, T et al. (2007). Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles. Mol Ther 15 1655-1662.
-
(2007)
Mol Ther
, vol.15
, pp. 1655-1662
-
-
Itaka, K.1
Ohba, S.2
Miyata, K.3
Kawaguchi, H.4
Nakamura, K.5
Takato, T.6
-
45
-
-
36048942316
-
Yin Yang 1 induces transcriptional activity of p73 through cooperation with E2F1
-
Wu, S, Murai, S, Kataoka, K and Miyagishi, M (2008). Yin Yang 1 induces transcriptional activity of p73 through cooperation with E2F1. Biochem Biophys Res Commun 365: 75-81.
-
(2008)
Biochem Biophys Res Commun
, vol.365
, pp. 75-81
-
-
Wu, S.1
Murai, S.2
Kataoka, K.3
Miyagishi, M.4
|