Functional and structural characterization of DR_0079 from Deinococcus radiodurans, a novel nudix hydrolase with a preference for cytosine (deoxy)ribonucleoside 5′-di- and triphosphates

Biochemistry

Volumn 47, Issue 25, 2008, Pages 6571-6582

  Buchko, Garry W ^a   Litvinova, Olga ^b   Robinson, Howard ^c   Yakunin, Alexander F ^b   Kennedy, Michael A ^a,d  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c BROOKHAVEN NATIONAL LABORATORY   (United States)

^d MIAMI UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEINOCOCCUS RADIODURANS; DIPHOSPHATE (DEHP); HYDROLASES; NUDIX HYDROLASE; RADIATION-RESISTANT BACTERIUM; RELATIVE ACTIVITIES; RIBONUCLEOSIDE; STRUCTURAL CHARACTERIZATIONS;

CYTOSINE; DEOXYRIBONUCLEOSIDE TRIPHOSPHATE; DIVALENT CATION; METAL ION; NUCLEOTIDE; NUDIX HYDROLASE; PHOSPHODIESTERASE; PHOSPHORUS; RIBONUCLEOSIDE DERIVATIVE; WATER;

ALPHA HELIX; ARTICLE; CHEMICAL ANALYSIS; CRYSTAL STRUCTURE; DEINOCOCCUS RADIODURANS; HYDROLYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PRIORITY JOURNAL;

BACTERIAL PROTEINS; BINDING, COMPETITIVE; CATALYTIC DOMAIN; CATIONS, DIVALENT; CRYSTALLIZATION; CYTIDINE DIPHOSPHATE; CYTIDINE TRIPHOSPHATE; DEINOCOCCUS; HELIX-TURN-HELIX MOTIFS; HYDROLYSIS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PYROPHOSPHATASES; STRUCTURE-ACTIVITY RELATIONSHIP; X-RAY DIFFRACTION;

BACTERIA (MICROORGANISMS); DEINOCOCCUS RADIODURANS;

EID: 45749140399     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800099d     Document Type: Article

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