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Searches were done as in (7)
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Searches were done as in (7).
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20
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13044311488
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note
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2 test, with each other, and with similarly sized samples of chromosome I chosen uniformly at random. These tests indicate that all three elements have significantly different trinucleotide composition (P < 0.01). Although the size of the plasmid is too small to obtain statistically meaningful comparisons of trinucleotide composition, its CC content is significantly different from the remaining genome (56% compared with 67%) (Tables 1 to 5).
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23
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note
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A gene is considered recently duplicated if its greatest degree of similarity is to another gene in the D. radiodurans genome relative to genes from other completed genomes.
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34
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13044283140
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note
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39
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0019331619
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The predicted molecular weight and isoelectric point are consistent with a protein that increases in abundance after irradiation (18). This protein is likely the nuclease reported by R. E. Mitchel [Biochim. Biophys. Acta 621, 138 (1980)].
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46
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13044300974
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note
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Supported by the U.S. Department of Energy, Office of Biological and Environmental Research, Cooperative Agreement DE-FCOZ-95ER61962. We thank E. V. Koonin for thoughtful contributions to this manuscript. Correspondence and requests for material should be addressed to C.M.F. (E-mail: drdb@tigr.org). The sequences have been deposited in GenBank with accession numbers AE00513, AE001825, AE001826, and AE001827 for chromosome I, chromosome II, the megaplasmid, and the plasmid, respectively.
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