High-resolution structure of unbound human immunodeficiency virus 1 subtype C protease: Implications of flap dynamics and drug resistance

Acta Crystallographica Section D: Biological Crystallography

Volumn 64, Issue 7, 2008, Pages 754-763

  Coman, Roxana M ^a   Robbins, Arthur H ^a   Goodenow, Maureen M ^b   Dunn, Ben M ^a   McKenna, Robert ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Drug resistance; Flap dynamics; HIV 1 subtype C protease

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; P16 PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS 1; PROTEINASE;

AMINO ACID SEQUENCE; ANTIVIRAL RESISTANCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; MOLECULAR GENETICS; MOTION; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, VIRAL; HIV PROTEASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOTION; SEQUENCE ALIGNMENT;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 45749114551     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S090744490801278X     Document Type: Article

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