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33747600674
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For example, see:
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For example, see:. Ishikawa H., Elliott G.I., Velcicky J., Choi Y., and Boger D.L. J. Am. Chem. Soc. 128 (2006) 10596-10612
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Elliott G.I., Fuchs J.R., Blagg B.S.J., Ishikawa H., Tao H., Yuan Z.-Q., and Boger D.L. J. Am. Chem. Soc. 128 (2006) 10589-10595
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Tao, H.5
Yuan, Z.-Q.6
Boger, D.L.7
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13
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0037174410
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Wilkie G.D., Elliott G.I., Blagg B.S.J., Wolkenberg S.E., Soenen D.R., Miller M.M., Pollack S., and Boger D.L. J. Am. Chem. Soc. 124 (2002) 11292-11294
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17
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0009174117
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For reviews on 1,3,4-oxadiazoles and leading references on their synthesis, see:. Weissberger A. (Ed), Wiley, New York
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For reviews on 1,3,4-oxadiazoles and leading references on their synthesis, see:. Behr L.C. In: Weissberger A. (Ed). The Chemistry of Heterocyclic Compounds Vol. 17 (1962), Wiley, New York 263-282
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84943378537
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Potts K.T., Katritzky A.R., and Rees C.W. (Eds), Pergamon, Oxford
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Hill J. In: Potts K.T., Katritzky A.R., and Rees C.W. (Eds). Comprehensive Heterocyclic Chemistry Vol. 6 (1984), Pergamon, Oxford 427-446
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84944041432
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Katritzky A.R., Rees C.W., and Scriven E.F.V. (Eds), Pergamon, Oxford
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Hill J. In: Katritzky A.R., Rees C.W., and Scriven E.F.V. (Eds). Comprehensive Heterocyclic Chemistry II Vol. 4 (1996), Pergamon, Oxford 267-287
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Hill, J.1
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29
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45649083679
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note
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The Boc-thiosemicarbazides 2 did not require purification for use in the next step.
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30
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45649083749
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note
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2 (108.6 mg, 0.4 mmol) and triethylamine (0.088 ml, 1.10 mmol). The reaction mixture was stirred at room temperature for 12 h. The reaction slurry was filtered through a short plug of Celite and the solvent was removed in vacuo. The crude products were purified using semi-automated flash chromatography (silica gel, EtOAc/hexanes 1:4) on a Biotage SP1 instrument.
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31
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45649084737
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note
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3Br 459.1024, found 459.1026.
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32
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45649085731
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note
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Crystallographic data (excluding structure factors) for the structure of compound 4Ce have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication number CCDC 683066.
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-
-
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33
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45649084205
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note
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Purities of 5 and 6 were determined by HPLC/LCMS with the UV absorption measured at 254 nm.
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34
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45649084318
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note
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{A figure is presented}.
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35
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10044264447
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Polymer-supported CMPI equivalent 8 is prepared by treatment of Wang resin with excess of 2-chloropyridine and triflic anhydride, see:
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Polymer-supported CMPI equivalent 8 is prepared by treatment of Wang resin with excess of 2-chloropyridine and triflic anhydride, see:. Crosignani S., Gonzalez J., and Swinnen D. Org. Lett. 6 (2004) 4579-4582
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(2004)
Org. Lett.
, vol.6
, pp. 4579-4582
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Crosignani, S.1
Gonzalez, J.2
Swinnen, D.3
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