MafG controls the hypoxic response of cells by accumulating HIF-1α in the nuclei

FEBS Letters

Volumn 582, Issue 16, 2008, Pages 2357-2364

  Ueda, Koji ^a   Xu, Jing ^a   Morimoto, Haruka ^a   Kawabe, Atsumi ^a   Imaoka, Susumu ^a  

^a KWANSEI GAKUIN UNIVERSITY   (Japan)

Author keywords

HIF 1 ; Hypoxia response; MafG; Nrf2

Indexed keywords

ERYTHROPOIETIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LUCIFERASE; MESSENGER RNA; TRANSCRIPTION FACTOR MAFG;

AMINO ACID SEQUENCE; ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; GENE TRANSLOCATION; HUMAN; HUMAN CELL; NUCLEOLUS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; SURFACE PLASMON RESONANCE;

CELL HYPOXIA; CELL LINE, TUMOR; CELL NUCLEUS; GENES, REPORTER; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MAFG TRANSCRIPTION FACTOR; REPRESSOR PROTEINS; RNA INTERFERENCE; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 45549110211     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.05.040     Document Type: Article

References (23)

1. Wang G.L., Jiang B.H., Rue E.A., and Semenza G.L. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl. Acad. Sci. USA 92 (1995) 5510-5514
2. Semenza G.L. Expression of hypoxia-inducible factor 1: mechanisms and consequences. Biochem. Pharmacol. 59 (2000) 47-53
3. Isaacs J.S., Jung Y.J., and Neckers L. Aryl hydrocarbon nuclear translocator (ARNT) promotes oxygen-independent stabilization of hypoxia-inducible factor-1alpha by modulating an Hsp90-dependent regulatory pathway. J. Biol. Chem. 279 (2004) 16128-16135
4. Yang J., Zhang L., Erbel P.J., Gardner K.H., Ding K., Garcia J.A., and Bruick R.K. Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor. J. Biol. Chem. 280 (2005) 36047-36054
5. Buchner J. Hsp90 & Co. - a holding for folding. Trend Biochem. Sci. 24 (1999) 136-141
6. Caplan A.J. Hsp90's secrets unfold: new insights from structural and functional studies. Trend Cell Biol. 9 (1999) 262-268
7. Motohashi H., Katsuoka F., Engel J.D., and Yamamoto M. Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway. Proc. Natl. Acad. Sci. USA 101 (2004) 6379-6384
8. Motohashi H., Shavit J.A., Igarashi K., Yamamoto M., and Engel J.D. The world according to Maf. Nucl. Acid Res. 25 (1997) 2953-2959
9. Kobayashi A., Kang M.I., Okawa H., Ohtsuji M., Zenke Y., Chiba T., Igarashi K., and Yamamoto M. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol. Cell. Biol. 24 (2004) 7130-7139
10. Kobayashi A., Kang M.I., Watai Y., Tong K.I., Shibata T., Uchida K., and Yamamoto M. Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1. Mol. Cell. Biol. 26 (2006) 221-229
11. Motohashi H., O'Connor T., Katsuoka F., Engel J.D., and Yamamoto M. Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors. Gene 294 (2002) 1-12
12. Shivdasani R.A., and Orkin S.H. Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2. Proc. Natl. Acad. Sci. USA 92 (1995) 8690-8694
13. Shavit J.A., Motohashi H., Onodera K., Akasaka J., Yamamoto M., and Engel J.D. Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice. Genes Dev. 12 (1998) 2164-2174
14. Tomita S., Ueno M., Sakamoto M., Kitahama Y., Ueki M., Maekawa N., Sakamoto H., Gassmann M., Kageyama R., Ueda N., Gonzalez F.J., and Takahama Y. Defective brain development in mice lacking the Hif-1alpha gene in neural cells. Mol. Cell. Biol. 23 (2003) 6739-6749
15. Osada M., Imaoka S., Sugimoto T., Hiroi T., and Funae Y. NADPH-cytochrome P-450 reductase in the plasma membrane modulates the activation of hypoxia-inducible factor 1. J. Biol. Chem. 277 (2002) 23367-23373
16. Lechertier T., Sirri V., Hernandez-Verdun D., and Roussel P. A B23-interacting sequence as a tool to visualize protein interactions in a cellular context. J. Cell Sci. 120 (2007) 265-275
17. Mylonis I., Chachami G., Samiotaki M., Panayotou G., Paraskeva E., Kalousi A., Georgatsou E., Bonanou S., and Simos G. Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha. J. Biol. Chem. 281 (2006) 33095-33106
18. Wan J., Imaoka S., Chow T., Hiroi T., Yabusaki Y., and Funae Y. Expression of four rat CYP2D isoforms in Saccharomyces cerevisiae and their catalytic specificity. Arch. Biochem. Biophys. 348 (1997) 383-390
19. Kang H.J., Kim H.J., Rih J.K., Mattson T.L., Kim K.W., Cho C.H., Isaacs J.S., and Bae I. BRCA1 plays a role in the hypoxic response by regulating HIF-1alpha stability and by modulating vascular endothelial growth factor expression. J. Biol. Chem. 281 (2006) 13047-13056
20. Igarashi K., Kataoka K., Itoh K., Hayashi N., Nishizawa M., and Yamamoto M. Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature 367 (1994) 568-572
21. Satoh T., Okamoto S.I., Cui J., Watanabe Y., Furuta K., Suzuki M., Tohyama K., and Lipton S.A. Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers. Proc. Natl. Acad. Sci. USA 103 (2006) 768-773
22. Jaakkola P., Mole D.R., Tian Y.M., Wilson M.I., Gielbert J., Gaskell S.J., Kriegsheim A., Hebestreit H.F., Mukherji M., Schofield C.J., Maxwell P.H., Pugh C.W., and Ratcliffe P.J. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 292 (2001) 468-472
23. Ivan M., Kondo K., Yang H., Kim W., Valiando J., Ohh M., Salic A., Asara J.M., Lane W.S., and Kaelin Jr. W.G. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 292 (2001) 464-468