Species-specific kinetics and zonation of hepatic DNA synthesis induced by ligands of PPARα

Toxicological Sciences

Volumn 104, Issue 1, 2008, Pages 74-85

  Al Kholaifi, Abdullah ^a   Amer, Abeer ^a   Jeffery, Brett ^a   Gray, Tim J B ^b   Roberts, Ruth A ^c   Bell, David R ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b Alnwick Research Centre   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

Author keywords

DNA synthesis; Hepatocyte; Liver growth; Peroxisome proliferation; PPAR

Indexed keywords

1,4 BIS(3,5 DICHLORO 2 PYRIDYLOXY)BENZENE; CIPROFIBRATE; DNA; LIGAND; METHYLCLOFENAPATE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; DNA SYNTHESIS; FEMALE; IMMUNOHISTOCHEMISTRY; KINETICS; LIVER CELL; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; RAT; ZONATION;

ANIMALS; CLOFIBRIC ACID; DNA; HEPATOCYTES; KINETICS; LIGANDS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; PEROXISOME PROLIFERATORS; PPAR ALPHA; RATS; RATS, INBRED F344; SPECIES SPECIFICITY;

MUS; RATTUS; RODENTIA;

EID: 45549110017     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn062     Document Type: Article

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