메뉴 건너뛰기




Volumn 45, Issue 3, 1997, Pages 393-401

Long-term oral application of 5-bromo-2-deoxyuridine does not reliably label proliferating immune cells in the LEW rat

Author keywords

Balb c mouse; blood; bone marrow; BrdU; LEW rat; long term labeling; lymph nodes; oral application; proliferation; spleen; thymus

Indexed keywords

BROXURIDINE; DNA; MONOCLONAL ANTIBODY;

EID: 0030978678     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549704500307     Document Type: Article
Times cited : (32)

References (39)
  • 2
    • 0015951114 scopus 로고
    • Three classes and four (sub)classes of rat immunoglobulins: IgM, IgA, IgE and IgG1, IgG2a, IgG2b, IgG2c
    • Bazin H, Beckers A, Querinjean P (1974) Three classes and four (sub)classes of rat immunoglobulins: IgM, IgA, IgE and IgG1, IgG2a, IgG2b, IgG2c. Eur J Immunol 4:44-48
    • (1974) Eur J Immunol , vol.4 , pp. 44-48
    • Bazin, H.1    Beckers, A.2    Querinjean, P.3
  • 4
    • 0024550698 scopus 로고
    • Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells
    • Chambers WH, Vujanovic NL, DeLeo AB, Olszowy MW, Herberman RB, Hiserodt JC (1989) Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells. J Exp Med 169:1373-1389
    • (1989) J Exp Med , vol.169 , pp. 1373-1389
    • Chambers, W.H.1    Vujanovic, N.L.2    DeLeo, A.B.3    Olszowy, M.W.4    Herberman, R.B.5    Hiserodt, J.C.6
  • 5
    • 0027394062 scopus 로고
    • Only a small proportion of splenic B cells in adults are short-lived virgin cells
    • Chan EY-T, MacLennan ICM (1993) Only a small proportion of splenic B cells in adults are short-lived virgin cells. Eur J Immunol 23:357-363
    • (1993) Eur J Immunol , vol.23 , pp. 357-363
    • Chan, E.Y.-T.1    MacLennan, I.C.M.2
  • 6
    • 0021050706 scopus 로고
    • Purine and pyrimidine metabolism in human T lymphocytes. Regulation of deoxyribonucleotide metabolism
    • Cohen A, Barankiewicz J, Eederman HM, Gelfand EW (1983) Purine and pyrimidine metabolism in human T lymphocytes. Regulation of deoxyribonucleotide metabolism. J Biol Chem 258:12334-12340
    • (1983) J Biol Chem , vol.258 , pp. 12334-12340
    • Cohen, A.1    Barankiewicz, J.2    Eederman, H.M.3    Gelfand, E.W.4
  • 7
    • 0018350570 scopus 로고
    • Different sensitivity of chromatin to acid denaturation in quiescent and cycling cells as revealed by flow cytometry
    • Darzynkiewicz Z, Traganos F, Andreeff M, Sharpless T, Melamed MR (1979) Different sensitivity of chromatin to acid denaturation in quiescent and cycling cells as revealed by flow cytometry. J Histochem Cytochem 27:478-485
    • (1979) J Histochem Cytochem , vol.27 , pp. 478-485
    • Darzynkiewicz, Z.1    Traganos, F.2    Andreeff, M.3    Sharpless, T.4    Melamed, M.R.5
  • 8
    • 0027258922 scopus 로고
    • Kinetics of B cell subpopulations in peripheral lymphoid tissues: Evidence for the presence of phenotypically distinct short-lived and long-lived B cell subsets
    • Deenen GJ, Kroese FGM (1993) Kinetics of B cell subpopulations in peripheral lymphoid tissues: evidence for the presence of phenotypically distinct short-lived and long-lived B cell subsets. Int Immunol 5:735-741
    • (1993) Int Immunol , vol.5 , pp. 735-741
    • Deenen, G.J.1    Kroese, F.G.M.2
  • 9
    • 0021969667 scopus 로고
    • The heterogeneity of mononuclear phagocytes in lymphoid organs: Distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3
    • Dijkstra CD, Döpp EA, Joling P, Kraal G (1985) The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. Immunology 54:589-599
    • (1985) Immunology , vol.54 , pp. 589-599
    • Dijkstra, C.D.1    Döpp, E.A.2    Joling, P.3    Kraal, G.4
  • 10
    • 0025339171 scopus 로고
    • The bulk of the peripheral B-cell pool in mice is stable and not rapidly renewed from the bone marrow
    • Förster I, Rajewsky K (1990) The bulk of the peripheral B-cell pool in mice is stable and not rapidly renewed from the bone marrow. Immunology 87:4781-4784
    • (1990) Immunology , vol.87 , pp. 4781-4784
    • Förster, I.1    Rajewsky, K.2
  • 11
    • 0022631918 scopus 로고
    • Life span of B lymphocytes: The experimental basis for conflicting results
    • Freitas AA, Rocha B, Coutinho AA (1986) Life span of B lymphocytes: the experimental basis for conflicting results. J Immunol 136:470-476
    • (1986) J Immunol , vol.136 , pp. 470-476
    • Freitas, A.A.1    Rocha, B.2    Coutinho, A.A.3
  • 12
    • 0022448951 scopus 로고
    • Enhancement of the expression of a rat neutrophil-specific cell surface antigen by activation with phorbol myristate acetate and concanavalin A
    • Gotoh S, Itoh M, Fujii Y, Arai S, Sendo F (1986) Enhancement of the expression of a rat neutrophil-specific cell surface antigen by activation with phorbol myristate acetate and concanavalin A. J Immunol 137:643-650
    • (1986) J Immunol , vol.137 , pp. 643-650
    • Gotoh, S.1    Itoh, M.2    Fujii, Y.3    Arai, S.4    Sendo, F.5
  • 13
    • 0017728872 scopus 로고
    • The effects of incorporation of 5-halogenated deoxyuridines into the DNA of eukaryotic cells
    • Goz B (1978) The effects of incorporation of 5-halogenated deoxyuridines into the DNA of eukaryotic cells. Pharmacol Rev 29: 249-272
    • (1978) Pharmacol Rev , vol.29 , pp. 249-272
    • Goz, B.1
  • 14
    • 0019903249 scopus 로고
    • Monoclonal antibody to 5-bromo and 5-iododeoxyuridine: A new reagent for detection of DNA replication
    • Gratzner HG (1982) Monoclonal antibody to 5-bromo and 5-iododeoxyuridine: a new reagent for detection of DNA replication. Science 218:474-475
    • (1982) Science , vol.218 , pp. 474-475
    • Gratzner, H.G.1
  • 15
    • 0023951443 scopus 로고
    • Population kinetics of rat peripheral B cells
    • Gray D (1988) Population kinetics of rat peripheral B cells. J Exp Med 167:805-816
    • (1988) J Exp Med , vol.167 , pp. 805-816
    • Gray, D.1
  • 16
    • 0023944129 scopus 로고
    • Effects of fixation time and enzymatic digestion on immunohistochemical demonstration of bromodeoxyuridine in formalin-fixed, paraffin-embedded tissue
    • Hayashi Y, Koike M, Matsutani M, Hoshino T (1988) Effects of fixation time and enzymatic digestion on immunohistochemical demonstration of bromodeoxyuridine in formalin-fixed, paraffin-embedded tissue. J Histochem Cytochem 36:511-514
    • (1988) J Histochem Cytochem , vol.36 , pp. 511-514
    • Hayashi, Y.1    Koike, M.2    Matsutani, M.3    Hoshino, T.4
  • 17
    • 0015027961 scopus 로고
    • Reutilization of thymidine in various groups of rat bone marrow cells
    • Heininger HJ, Feinendegen LE, Bürki K (1971) Reutilization of thymidine in various groups of rat bone marrow cells. Blood 37: 340-348
    • (1971) Blood , vol.37 , pp. 340-348
    • Heininger, H.J.1    Feinendegen, L.E.2    Bürki, K.3
  • 18
    • 0024840038 scopus 로고
    • Double labelling of tissue combining tritiated thymidine autoradiography with immunodetection of bromodeoxyuridine: The autoradiographic significance of inhibition of thymidine incorporation into DNA by bromodeoxyuridine given simultaneously
    • Hume WJ, Thompson J (1989) Double labelling of tissue combining tritiated thymidine autoradiography with immunodetection of bromodeoxyuridine: the autoradiographic significance of inhibition of thymidine incorporation into DNA by bromodeoxyuridine given simultaneously. Cell Tissue Kinet 22:393-399
    • (1989) Cell Tissue Kinet , vol.22 , pp. 393-399
    • Hume, W.J.1    Thompson, J.2
  • 19
    • 0024490423 scopus 로고
    • A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes
    • Hünig T, Wallny H-J, Hartley JK, Lawetzky A, Tiefenthaler G (1989) A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes. J Exp Med 169:73-86
    • (1989) J Exp Med , vol.169 , pp. 73-86
    • Hünig, T.1    Wallny, H.-J.2    Hartley, J.K.3    Lawetzky, A.4    Tiefenthaler, G.5
  • 20
    • 0000239057 scopus 로고
    • The fate of 5-bromodeoxyuridine, 5-bromodeoxycytidine, and 5-iododeoxycytidine in man
    • Kriss JP, Maruyama Y, Tung LA, Bond SB, Revesz L (1963) The fate of 5-bromodeoxyuridine, 5-bromodeoxycytidine, and 5-iododeoxycytidine in man. Cancer Res 23:260-268
    • (1963) Cancer Res , vol.23 , pp. 260-268
    • Kriss, J.P.1    Maruyama, Y.2    Tung, L.A.3    Bond, S.B.4    Revesz, L.5
  • 21
    • 0000107359 scopus 로고
    • The distribution and fate of bromodeoxyuridine and bromodeoxycytidine in the mouse and rat
    • Kriss JP, Revesz L (1962) The distribution and fate of bromodeoxyuridine and bromodeoxycytidine in the mouse and rat. Cancer Res 22:254-265
    • (1962) Cancer Res , vol.22 , pp. 254-265
    • Kriss, J.P.1    Revesz, L.2
  • 22
    • 0029068344 scopus 로고
    • Identification and kinetics of two recently bone marrow derived B cell populations in peripheral lymphoid tissues
    • Kroese FGM, De Boer NK, De Boer T, Niewenhuis P, Kantor AB, Deenen GJ (1995) Identification and kinetics of two recently bone marrow derived B cell populations in peripheral lymphoid tissues. Cell Immunol 162:185-193
    • (1995) Cell Immunol , vol.162 , pp. 185-193
    • Kroese, F.G.M.1    De Boer, N.K.2    De Boer, T.3    Niewenhuis, P.4    Kantor, A.B.5    Deenen, G.J.6
  • 24
    • 0014451548 scopus 로고
    • Effect of tritiated thymidine and 5-bromodesoxyuridine on development of immunologically competent lymphocytes
    • McGregor DD (1969) Effect of tritiated thymidine and 5-bromodesoxyuridine on development of immunologically competent lymphocytes. Immunology 16:83-90
    • (1969) Immunology , vol.16 , pp. 83-90
    • McGregor, D.D.1
  • 26
    • 0027533636 scopus 로고
    • Administration of bromodeoxyuridine in early postnatal rats results in lung changes at maturity
    • Nagai A, Masumiya H, Yasui S, Aoshiba K, Ishihara Y, Konno K (1993) Administration of bromodeoxyuridine in early postnatal rats results in lung changes at maturity. Exp Lung Res 19:203-219
    • (1993) Exp Lung Res , vol.19 , pp. 203-219
    • Nagai, A.1    Masumiya, H.2    Yasui, S.3    Aoshiba, K.4    Ishihara, Y.5    Konno, K.6
  • 27
    • 0025150803 scopus 로고
    • Accumulation of bromodeoxyuridine-labelled cells in central and peripheral lymphoid organs: Minimal estimates of production and turnover rates of mature lymphocytes
    • Rocha B, Penit C, Baron C, Vasseur F, Dautigny N, Freitas AA (1990) Accumulation of bromodeoxyuridine-labelled cells in central and peripheral lymphoid organs: minimal estimates of production and turnover rates of mature lymphocytes. Eur J Immunol 20:1697-1708
    • (1990) Eur J Immunol , vol.20 , pp. 1697-1708
    • Rocha, B.1    Penit, C.2    Baron, C.3    Vasseur, F.4    Dautigny, N.5    Freitas, A.A.6
  • 28
    • 0025972179 scopus 로고
    • Dividing cells in bone marrow and spleen incorporate bromodeoxyuridine with high efficiency
    • Schittek B, Rajewsky K, Förster I (1991) Dividing cells in bone marrow and spleen incorporate bromodeoxyuridine with high efficiency. Eur J Immunol 21:235-238
    • (1991) Eur J Immunol , vol.21 , pp. 235-238
    • Schittek, B.1    Rajewsky, K.2    Förster, I.3
  • 30
    • 0024414008 scopus 로고
    • 5-bromo-2′-deoxyuridine blocks myogenesis by extinguishing expression of MyoD1
    • Tapscott SJ, Lassar AB, Davis RL, Weintraub H (1989) 5-bromo-2′-deoxyuridine blocks myogenesis by extinguishing expression of MyoD1. Science 245:532-536
    • (1989) Science , vol.245 , pp. 532-536
    • Tapscott, S.J.1    Lassar, A.B.2    Davis, R.L.3    Weintraub, H.4
  • 31
    • 0027156853 scopus 로고
    • 5-Bromo-2-deoxyuridine regulates invasiveness and expression of integrins and matrix-degrading proteinases in a differentiated hamster melanoma cell
    • Thomas L, Chan PW, Chang S, Damsky C (1993) 5-Bromo-2-deoxyuridine regulates invasiveness and expression of integrins and matrix-degrading proteinases in a differentiated hamster melanoma cell. J Cell Sci 105:191-201
    • (1993) J Cell Sci , vol.105 , pp. 191-201
    • Thomas, L.1    Chan, P.W.2    Chang, S.3    Damsky, C.4
  • 32
    • 0028267677 scopus 로고
    • Turnover of naive- and memory-phenotype T cells
    • Tough DF, Sprent J (1994) Turnover of naive- and memory-phenotype T cells. J Exp Med 179:1127-1135
    • (1994) J Exp Med , vol.179 , pp. 1127-1135
    • Tough, D.F.1    Sprent, J.2
  • 33
    • 0027480021 scopus 로고
    • Practical suggestions for successful immunoenzyme double-staining experiments
    • van der Loos CM, Becker AE, van den Oord JJ (1993) Practical suggestions for successful immunoenzyme double-staining experiments. Histochem J 25:1-13
    • (1993) Histochem J , vol.25 , pp. 1-13
    • Van Der Loos, C.M.1    Becker, A.E.2    Van Den Oord, J.J.3
  • 34
    • 0027461784 scopus 로고
    • The life span of naive Ó/β T cells in secondary lymphoid organs
    • von Boehmer H, Hafen K (1993) The life span of naive Ó/β T cells in secondary lymphoid organs. J Exp Med 177:891-896
    • (1993) J Exp Med , vol.177 , pp. 891-896
    • Von Boehmer, H.1    Hafen, K.2
  • 35
    • 0026007673 scopus 로고
    • Dose response of hepatic and renal DNA synthetic rates to continuous exposure of bromodeoxyuridine (BrdU) via slow-release pellets or osmotic minipumps in male B6C3F1 mite
    • Weghorst CM, Henneman JR, Ward JM (1991) Dose response of hepatic and renal DNA synthetic rates to continuous exposure of bromodeoxyuridine (BrdU) via slow-release pellets or osmotic minipumps in male B6C3F1 mite. J Histochem Cytochem 39: 177-184
    • (1991) J Histochem Cytochem , vol.39 , pp. 177-184
    • Weghorst, C.M.1    Henneman, J.R.2    Ward, J.M.3
  • 36
    • 0024364835 scopus 로고
    • Profileration of lymphocyte subsets in the adult rat: A comparison of different lymphoid organs
    • Westermann J, Ronneberg S, Fritz FJ, Pabst R (1989) Profileration of lymphocyte subsets in the adult rat: a comparison of different lymphoid organs. Eur J Immunol 19:1087-1093
    • (1989) Eur J Immunol , vol.19 , pp. 1087-1093
    • Westermann, J.1    Ronneberg, S.2    Fritz, F.J.3    Pabst, R.4
  • 37
    • 0029832966 scopus 로고    scopus 로고
    • Both activated and nonactivated leukocytes from the periphery continuously enter the thymic medulla of adult rats: Phenotypes, sources and magnitude of traffic
    • Westermann J, Smith T, Peters U, Tschernig T, Pabst R, Steinhoff G, Sparshott SM, Bell EB (1996) Both activated and nonactivated leukocytes from the periphery continuously enter the thymic medulla of adult rats: phenotypes, sources and magnitude of traffic. Eur J Immunol 26:1866-1874
    • (1996) Eur J Immunol , vol.26 , pp. 1866-1874
    • Westermann, J.1    Smith, T.2    Peters, U.3    Tschernig, T.4    Pabst, R.5    Steinhoff, G.6    Sparshott, S.M.7    Bell, E.B.8
  • 38
    • 0018168847 scopus 로고
    • T lymphocyte heterogeneity in the rat: Separation of functional subpopulations using a monoclonal antibody
    • White RAH, Mason DW, Williams AF, Galfre G, Milstein C (1978) T lymphocyte heterogeneity in the rat: separation of functional subpopulations using a monoclonal antibody. J Exp Med 148:664-673
    • (1978) J Exp Med , vol.148 , pp. 664-673
    • White, R.A.H.1    Mason, D.W.2    Williams, A.F.3    Galfre, G.4    Milstein, C.5
  • 39
    • 84990581154 scopus 로고
    • Use of bromodeoxyuridine for cell kinetic studies in intact animals
    • Wynford-Thomas D, Williams ED (1986) Use of bromodeoxyuridine for cell kinetic studies in intact animals. Cell Tissue Kinet 19:183-194
    • (1986) Cell Tissue Kinet , vol.19 , pp. 183-194
    • Wynford-Thomas, D.1    Williams, E.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.