Molecular analysis of peroxisome proliferation in the hamster

Toxicology and Applied Pharmacology

Volumn 197, Issue 1, 2004, Pages 9-18

  Choudhury, Agharul I ^a   Sims, Helen M ^a   Horley, Neill J ^a   Roberts, Ruth A ^b,c   Tomlinson, Simon R ^a   Salter, Andrew M ^a   Bruce, Mary ^a   Shaw, P Nicholas ^a   Kendall, David ^a   Barrett, David A ^a   Bell, David R ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

^c SANOFI   (France)

Author keywords

CYP4A; Peroxisome; PPAR

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 4A; LAURIC ACID DERIVATIVE; METHYLCLOFENAPATE; PEROXISOME PROLIFERATOR; PIRINIXIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; GENETIC CODE; HAMSTER; HEPATOMEGALY; HYPOLIPEMIA; LIVER; MOLECULAR CLONING; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PEROXISOME;

ALKANE 1-MONOOXYGENASE; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CRICETINAE; DNA, COMPLEMENTARY; ENZYME INDUCTION; GUINEA PIGS; HYDROXYLATION; LAURIC ACIDS; LIPIDS; LIVER; MESOCRICETUS; MICE; MOLECULAR SEQUENCE DATA; PEROXISOME PROLIFERATORS; PEROXISOMES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA; TRANSCRIPTION FACTORS;

CAVIA PORCELLUS; CRICETINAE; SUS SCROFA;

EID: 2342584188     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2004.01.019     Document Type: Article

References (31)

1. Ashby J., Brady A., Elcombe C.R., Elliott B.M., Ishmael J., Odum J., Tugwood J.D., Kettle S., Purchase I.F.H. Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis. Human Exp. Toxicol. 13:1994;S1-S117
2. Bell D.R., Elcombe C.R. Induction of Acyl-Coa oxidase and Cytochrome-P450iva1 Rna in rat primary hepatocyte culture by peroxisome proliferators. Biochem. J. 280:1991;249-253
3. Bell D.R., Elcombe C.R. Regulation of differentially spliced transcripts of Acyl-Coa oxidase in the rat. Biochim. Biophys. Acta. 1090:1991;211-215
4. Bell D.R., Bars R.G., Gibson G.G., Elcombe C.R. Localization and differential induction of cytochrome-P450iva and Acyl-Coa oxidase in rat-liver. Biochem. J. 275:1991;247-252
5. Bell D.R., Bars R.G., Elcombe C.R. Differential tissue-specific expression and induction of cytochrome-P450iva1 and Acyl-Coa oxidase. Eur. J. Biochem. 206:1992;979-986
6. Bell D.R., Plant N.J., Rider C.G., Na L., Brown S., Ateitalla I., Acharya S.K., Davies M.H., Elias E., Jenkins N.A., Gilbert D.J., Copeland N.G., Elcombe C.R. Species-specific induction of cytochrome-P-450 4a-Rnas - Pcr cloning of partial guinea-pig, human and mouse Cyp4a-Cdnas. Biochem. J. 294:1993;173-180
7. Bell A.R., Savory R., Horley N.J., Choudhury A.I., Dickins M., Gray T.J.B., Salter A.M., Bell D.R. Molecular basis of non-responsiveness to peroxisome proliferators: the guinea-pig PPAR alpha is functional and mediates peroxisome proliferator-induced hypolipidaemia. Biochem. J. 332:1998;689-693
8. Calzone F.J., Britten R.J., Davidson E.H. Mapping of gene transcripts by nuclease protection assays and Cdna primer extension. Methods Enzymol. 152:1987;611-632
9. Cathala G., Savouret J.F., Mendez B., West B.L., Karin M., Martial J.A., Baxter J.D. A method for isolation of intact, translationally active ribonucleic-acid. DNA-J. Mol. Cell. Biol. 2:1983;329-335
10. Choudhury A.I. PPAR Alpha in peroxisome proliferation: molecular characterisation and species differences. Biological Sciences. 2000;University of Nottingham, Nottingham
11. Demontellano P.R.O., Reich N.O. Specific inactivation of hepatic fatty-acid hydroxylases by acetylenic fatty-acids. J. Biol. Chem. 259:1984;4136-4141
12. Holmes V.E., Bruce M., Shaw P.N., Bell D.R., Fan M.-Q., Barrett D.A. A gas chromatography-mass spectrometry based method for the measurement of fatty-acid w and w-1 hydroxylation kinetics by CYP4A1 using an artificial membrane system. Anal. Biochem. 325:2004;354-363
13. Issemann I., Green S. Activation of a member of the steroid-hormone receptor superfamily by peroxisome proliferators. Nature. 347:1990;645-650
14. Jones P.S., Savory R., Barratt P., Bell A.R., Gray T.J.B., Jenkins N.A., Gilbert D.J., Copeland N.G., Bell D.R. Chromosomal localization, inducibility, tissue-specific expression and strain differences in 3 murine peroxisome-proliferator-activated-receptor genes. Eur. J. Biochem. 233:1995;219-226
15. Lake B.G. Mechanisms of hepatocarcinogenicity of peroxisome-proliferating drugs and chemicals. Annu. Rev. Pharmacol. Toxicol. 35:1995;483-507
16. Lake B.G., Gray T.J.B., Hodder K.D., Beamand J.A., Stubberfield C.R., Gangolli S.D. Effects of peroxisome proliferators invivo and in primary hepatocyte cultures from Chinese and Syrian-hamsters. Arch. Toxicol. 1986;167
17. Lake B.G., Evans J.G., Gray T.J.B., Korosi S.A., North C.J. Comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, Syrian-hamster, guinea-pig, and marmoset. Toxicol. Appl. Pharmacol. 99:1989;148-160
18. Lake B.G., Evans J.G., Cunninghame M.E., Price R.J. Comparison of the hepatic - Effects of nafenopin and Wy-14, 643 on peroxisome proliferation and cell replication in the rat and Syrian-hamster. Environ. Health Perspect. 101:1993;241-247
19. Lake B.G., Price R.J., Cunninghame M.E., Walters D.G. Comparison of the effects of di-(2-ethylhexyl)adipate on hepatic peroxisome proliferation and cell replication in the rat and mouse. Toxicology. 123:1997;217-226
20. Lake B.G., Rumsby P.C., Price R.J., Cunninghame M.E. Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-beta 1 gene expression in the rat, Syrian hamster and guinea pig. Mutat. Res., Fundam. Mol. Mech. Mutagen. 448:2000;213-225
21. Lambe K.G., Woodyatt N.J., Macdonald N., Chevalier S., Roberts R.A. Species differences in sequence and activity of the peroxisome proliferator response element (PPRE) within the acyl CoA oxidase gene promoter. Toxicol. Lett. 110:1999;119-127
22. Lee S.S.T., Pineau T., Drago J., Lee E.J., Owens J.W., Kroetz D.L., Fernandezsalguero P.M., Westphal H., Gonzalez F.J. Targeted disruption of the alpha-isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15:1995;3012-3022
23. Pacot C., Petit M., Rollin M., Behechti N., Moisant M., Deslex P., Althoff J., Lhuguenot J.C., Latruffe N. Difference between guinea pig and rat in the liver peroxisomal response to equivalent plasmatic level of ciprofibrate. Arch. Biochem. Biophys. 327:1996;181-188
24. Palmer C.N.A., Hsu M.H., Griffin K.J., Raucy J.L., Johnson E.F. Peroxisome proliferator activated receptor-alpha expression in human liver. Mol. Pharmacol. 53:1998;14-22
25. Peters J.M., Cattley R.C., Gonzalez F.J. Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14, 643. Carcinogenesis. 18:1997;2029-2033
26. Pineau T., Hudgins W.R., Liu L., Chen L.C., Sher T., Gonzalez F.J., Samid D. Activation of a human peroxisome proliferator-activated receptor by the antitumor agent phenylacetate and its analogs. Biochem. Pharmacol. 52:1996;659-667
27. Plant N.J., Horley N.J., Dickins M., Hasmall S., Elcombe C.R., Bell D.R. The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate. Carcinogenesis. 19:1998;1521-1527
28. Plant N.J., Horley N.J., Savory R.L., Elcombe C.R., Gray T.J.B., Bell D.R. The peroxisome proliferators are hepatocyte mitogens in chemically-defined media: glucocorticoid-induced PPAR alpha is linked to peroxisome proliferator mitogenesis. Carcinogenesis. 19:1998;925-931
29. Sher T., Yi H.F., McBride O.W., Gonzalez F.J. Cdna cloning, chromosomal mapping, and functional - Characterization of the human peroxisome proliferator activated receptor. Biochemistry. 32:1993;5598-5604
30. Tugwood J.D., Issemann I., Anderson R.G., Bundell K.R., McPheat W.L., Green S. The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat Acyl Coa oxidase gene. EMBO J. 11:1992;433-439
31. Tugwood J.D., Holden P.R., James N.H., Prince R.A., Roberts R.A. A peroxisome proliferator-activated receptor-alpha (PPAR alpha) cDNA cloned from guinea-pig liver encodes a protein with similar properties to the mouse PPAR alpha: implications for species differences in responses to peroxisome proliferators. Arch. Toxicol. 72:1998;169-177