Characterization of EHT 1864, a Novel Small Molecule Inhibitor of Rac Family Small GTPases

Methods in Enzymology

Volumn 439, Issue , 2008, Pages 111-129

  Onesto, Cercina ^a   Shutes, Adam ^a   Picard, Virginie ^b   Schweighoffer, Fabien ^b   Der, Channing J ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b ExonHit Therapeutics   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EHT 1864; PROTEIN INHIBITOR; PROTEIN KINASE; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; P21 ACTIVATED KINASE; PAK1 PROTEIN, HUMAN; PYRONE DERIVATIVE; QUINOLINE DERIVATIVE; RAC1 PROTEIN; RAC1 PROTEIN, HUMAN;

CANCER CELL; CELL FUNCTION; CELL INVASION; CELL PROLIFERATION; CELL TRANSFORMATION; CHEMICAL ANALYSIS; DOWNSTREAM PROCESSING; METASTASIS; MOLECULE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROCESSING; REVIEW; ANIMAL; ARTICLE; CELL STRAIN 3T3; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG ANTAGONISM; DRUG EFFECT; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; MOUSE;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MICE; MICROSCOPY, CONFOCAL; NIH 3T3 CELLS; P21-ACTIVATED KINASES; PYRONES; QUINOLINES; RAC1 GTP-BINDING PROTEIN;

EID: 45549094636     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(07)00409-0     Document Type: Review

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