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Volumn 73, Issue 5-6, 2008, Pages 430-438

GM3 signals regulating TNF-alpha expression are mediated by rictor and Arhgdib in mouse melanoma B16 cells

Author keywords

Arhgdib; Ganglioside; GM3; MTOR; Raptor; Rictor; Tumor necrosis factor

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CARRIER PROTEIN; GANGLIOSIDE GM3; GUANOSINE DIPHOSPHATE; LY 303511; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN ARHGDIB; PROTEIN KINASE B; PROTEIN RAPTOR; PROTEIN RICTOR; RAPAMYCIN; REGULATOR PROTEIN; RHO FACTOR; SERINE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR SUPPRESSOR PROTEIN;

EID: 45549090184     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000136801     Document Type: Article
Times cited : (14)

References (34)
  • 1
    • 0021572879 scopus 로고
    • Tumor-associated carbohydrate antigens
    • Hakomori S: Tumor-associated carbohydrate antigens. Annu Rev Immunol 1984;2:103-126.
    • (1984) Annu Rev Immunol , vol.2 , pp. 103-126
    • Hakomori, S.1
  • 3
    • 0027418926 scopus 로고
    • Shedding of GD2 ganglioside in patients with retinoblastoma
    • Portoukalian J, David MJ, Gain P, Richard M: Shedding of GD2 ganglioside in patients with retinoblastoma. Int J Cancer 1993;35:948-951.
    • (1993) Int J Cancer , vol.35 , pp. 948-951
    • Portoukalian, J.1    David, M.J.2    Gain, P.3    Richard, M.4
  • 4
    • 0343208997 scopus 로고
    • Disialoganglioside GD3 on human melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis
    • Cheresh DA, Honsik CJ, Staffileno LK, Jung G, Reisfeld RA: Disialoganglioside GD3 on human melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis. Proc Natl Acad Sci USA 1985;82:5155-5159.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 5155-5159
    • Cheresh, D.A.1    Honsik, C.J.2    Staffileno, L.K.3    Jung, G.4    Reisfeld, R.A.5
  • 5
    • 0024368879 scopus 로고
    • Tumor size-dependent elevations of serum gangliosides in patients with head and neck carcinomas
    • Portoukalian J, David MJ, Shen X, Richard M, Dubreuil C: Tumor size-dependent elevations of serum gangliosides in patients with head and neck carcinomas. Biochem Int 1989;18:759-765.
    • (1989) Biochem Int , vol.18 , pp. 759-765
    • Portoukalian, J.1    David, M.J.2    Shen, X.3    Richard, M.4    Dubreuil, C.5
  • 6
    • 0023353680 scopus 로고
    • Gangliosides shed by tumor cells enhance tumor formation in mice
    • Ladisch S, Kitada S, Hays EF: Gangliosides shed by tumor cells enhance tumor formation in mice. J Clin Invest 1987;79:1879-1882.
    • (1987) J Clin Invest , vol.79 , pp. 1879-1882
    • Ladisch, S.1    Kitada, S.2    Hays, E.F.3
  • 7
    • 0028890740 scopus 로고
    • Human tumor gangliosides inhibit murine immune responses in vivo
    • Li R, Villacreses N, Ladisch S: Human tumor gangliosides inhibit murine immune responses in vivo. Cancer Res 1995;55:211-214.
    • (1995) Cancer Res , vol.55 , pp. 211-214
    • Li, R.1    Villacreses, N.2    Ladisch, S.3
  • 8
    • 0033213878 scopus 로고    scopus 로고
    • Tumor gangliosides inhibit the tumor specific immune response
    • McKallip R, Li R, Ladisch S: Tumor gangliosides inhibit the tumor specific immune response. J Immunol 1999;163:3718-3726.
    • (1999) J Immunol , vol.163 , pp. 3718-3726
    • McKallip, R.1    Li, R.2    Ladisch, S.3
  • 9
    • 0034616635 scopus 로고    scopus 로고
    • Influence of cellular ganglioside on tumor formation
    • Deng W, Li R, Ladisch S: Influence of cellular ganglioside on tumor formation. J Natl Cancer Inst 2000;92:912-917.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 912-917
    • Deng, W.1    Li, R.2    Ladisch, S.3
  • 11
    • 33646516647 scopus 로고    scopus 로고
    • Gangliosides trigger inflammatory responses via TLR4 in brain glia
    • Jou I, Lee JH, Park SY, Yoon HJ, Joe EH, Park EJ: Gangliosides trigger inflammatory responses via TLR4 in brain glia. Am J Pathol 2006;168:1619-1630.
    • (2006) Am J Pathol , vol.168 , pp. 1619-1630
    • Jou, I.1    Lee, J.H.2    Park, S.Y.3    Yoon, H.J.4    Joe, E.H.5    Park, E.J.6
  • 13
    • 0029900295 scopus 로고    scopus 로고
    • The tumor necrosis factor ligand and receptor families
    • Bazzoni F, Beutler B: The tumor necrosis factor ligand and receptor families. N Engl J Med 1996;334:1717-1725.
    • (1996) N Engl J Med , vol.334 , pp. 1717-1725
    • Bazzoni, F.1    Beutler, B.2
  • 14
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley RM, Killeen N, Lenardo MJ: The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 2001;104:487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 15
    • 33947381060 scopus 로고    scopus 로고
    • Positive regulation of tumor necrosis factor alpha by ganglioside GM3 through Akt in mouse melanoma B16 cells
    • Wang P, Wu P, Zhang J, Sato T, Yamagata S, Yamagata T: Positive regulation of tumor necrosis factor alpha by ganglioside GM3 through Akt in mouse melanoma B16 cells. Biochem Biophys Res Commun 2007;356:438-443.
    • (2007) Biochem Biophys Res Commun , vol.356 , pp. 438-443
    • Wang, P.1    Wu, P.2    Zhang, J.3    Sato, T.4    Yamagata, S.5    Yamagata, T.6
  • 17
    • 23144467910 scopus 로고    scopus 로고
    • An expanding role for mTOR in cancer
    • Guertin DA, Sabatini DM: An expanding role for mTOR in cancer. Trends Mol Med 2005;11:353-361.
    • (2005) Trends Mol Med , vol.11 , pp. 353-361
    • Guertin, D.A.1    Sabatini, D.M.2
  • 19
    • 30644468118 scopus 로고    scopus 로고
    • mTOR and cancer: Reason for dancing at the crossroads?
    • Thomas GV: mTOR and cancer: reason for dancing at the crossroads? Curr Opin Genet Dev 2006;16:78-84.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 78-84
    • Thomas, G.V.1
  • 20
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • Hay N, Sonenberg N: Upstream and downstream of mTOR. Genes Dev 2004;18:1926-1945.
    • (2004) Genes Dev , vol.18 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 21
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signaling
    • Inoki K, Li Y, Zhu T, Wu J, Guan KL: TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signaling. Nat Cell Biol 2002;4:648-657.
    • (2002) Nat Cell Biol , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.L.5
  • 22
    • 33749076673 scopus 로고    scopus 로고
    • SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
    • Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B: SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 2006;127:125-137.
    • (2006) Cell , vol.127 , pp. 125-137
    • Jacinto, E.1    Facchinetti, V.2    Liu, D.3    Soto, N.4    Wei, S.5    Jung, S.Y.6    Huang, Q.7    Qin, J.8    Su, B.9
  • 24
    • 0036191304 scopus 로고    scopus 로고
    • Rho GTPases in transformation and metastasis
    • Jaffe AB, Hall A: Rho GTPases in transformation and metastasis. Adv Cancer Res 2002;84:57-80.
    • (2002) Adv Cancer Res , vol.84 , pp. 57-80
    • Jaffe, A.B.1    Hall, A.2
  • 25
    • 84863698357 scopus 로고    scopus 로고
    • Ganglioside GD1a regulation of caveolin-1 and Stim1 expression in mouse FBJ cells: Augmented expression of caveolin-1 and stim1 in cells with increased GD1a content
    • Wang L, Takaku S, Wang P, Hu D, Hyuga S, Sato T, Yamagata S, Yamagata T: Ganglioside GD1a regulation of caveolin-1 and Stim1 expression in mouse FBJ cells: augmented expression of caveolin-1 and stim1 in cells with increased GD1a content. Glycoconj J 2006;23:303-315.
    • (2006) Glycoconj J , vol.23 , pp. 303-315
    • Wang, L.1    Takaku, S.2    Wang, P.3    Hu, D.4    Hyuga, S.5    Sato, T.6    Yamagata, S.7    Yamagata, T.8
  • 26
    • 23944439701 scopus 로고    scopus 로고
    • LY303511 (2-piperazinyl-8-phenyl-4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms
    • Kristof AS, Pacheco-Rodriguez G, Schremmer B, Moss J: LY303511 (2-piperazinyl-8-phenyl-4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms. J Pharmacol Exp Ther 2005;314:1134-1143.
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 1134-1143
    • Kristof, A.S.1    Pacheco-Rodriguez, G.2    Schremmer, B.3    Moss, J.4
  • 27
    • 11844304072 scopus 로고    scopus 로고
    • Restraining PI3K: MTOR signalling goes back to the membrane
    • Harrington LS, Findlay GM, Lamb RF: Restraining PI3K: mTOR signalling goes back to the membrane. Trends Biochem Sci 2005;30:35-42.
    • (2005) Trends Biochem Sci , vol.30 , pp. 35-42
    • Harrington, L.S.1    Findlay, G.M.2    Lamb, R.F.3
  • 28
    • 33645801404 scopus 로고    scopus 로고
    • Opposite effects of wortmannin and 2-(4-morpholinyl)-8-phenyl-1(4H)-benzopyran- 4-one hydrochloride on toll-like receptor-mediated nitric oxide production: Negative regulation of nuclear factor-κB by phosphoinositide 3-kinase
    • Hazeki K, Kinoshita S, Matsumura T, Nigorikawa K, Kubo H, Hazeki O: Opposite effects of wortmannin and 2-(4-morpholinyl)-8-phenyl-1(4H)-benzopyran- 4-one hydrochloride on toll-like receptor-mediated nitric oxide production: negative regulation of nuclear factor-κB by phosphoinositide 3-kinase. Mol Pharmacol 2006;69:1717-1724.
    • (2006) Mol Pharmacol , vol.69 , pp. 1717-1724
    • Hazeki, K.1    Kinoshita, S.2    Matsumura, T.3    Nigorikawa, K.4    Kubo, H.5    Hazeki, O.6
  • 29
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering BM, Coffer PJ: Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 1995;376:599-602.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 30
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke TF, Yang S, Chan TO, Datta K, Kazlauskas A, Morrison DK, Kaplan DR, Tsichlis PN: The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 1995;81:727-736.
    • (1995) Cell , vol.81 , pp. 727-736
    • Franke, T.F.1    Yang, S.2    Chan, T.O.3    Datta, K.4    Kazlauskas, A.5    Morrison, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 31
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov DD, Guertin DA, Ali SM, Sabatini DM: Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005;307:1098-1101.
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 34
    • 45549097766 scopus 로고    scopus 로고
    • Ganglioside GM3 positively regulates Arhgdib, a Rho GTPase regulator, to suppress anchorage-independent growth via PI3K/AKT/mTOR pathway in mouse melanoma B16 cells
    • In preparation
    • Wang P, Wu P, Zhang J, Sato T, Yamagat S, Yamagata T: Ganglioside GM3 positively regulates Arhgdib, a Rho GTPase regulator, to suppress anchorage-independent growth via PI3K/AKT/mTOR pathway in mouse melanoma B16 cells. In preparation.
    • Wang, P.1    Wu, P.2    Zhang, J.3    Sato, T.4    Yamagat, S.5    Yamagata, T.6


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