-
1
-
-
0021572879
-
Tumor-associated carbohydrate antigens
-
Hakomori S: Tumor-associated carbohydrate antigens. Annu Rev Immunol 1984;2:103-126.
-
(1984)
Annu Rev Immunol
, vol.2
, pp. 103-126
-
-
Hakomori, S.1
-
2
-
-
0023163749
-
Shedding of GD2 ganglioside by human neuroblastoma
-
Ladisch S, Wu ZL, Feig S, Ulsh L, Schwartz E, Floutsis G, Wiley F, Lenarsky C, Seeger R: Shedding of GD2 ganglioside by human neuroblastoma. Int J Cancer 1987;39:73-76.
-
(1987)
Int J Cancer
, vol.39
, pp. 73-76
-
-
Ladisch, S.1
Wu, Z.L.2
Feig, S.3
Ulsh, L.4
Schwartz, E.5
Floutsis, G.6
Wiley, F.7
Lenarsky, C.8
Seeger, R.9
-
4
-
-
0343208997
-
Disialoganglioside GD3 on human melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis
-
Cheresh DA, Honsik CJ, Staffileno LK, Jung G, Reisfeld RA: Disialoganglioside GD3 on human melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis. Proc Natl Acad Sci USA 1985;82:5155-5159.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 5155-5159
-
-
Cheresh, D.A.1
Honsik, C.J.2
Staffileno, L.K.3
Jung, G.4
Reisfeld, R.A.5
-
5
-
-
0024368879
-
Tumor size-dependent elevations of serum gangliosides in patients with head and neck carcinomas
-
Portoukalian J, David MJ, Shen X, Richard M, Dubreuil C: Tumor size-dependent elevations of serum gangliosides in patients with head and neck carcinomas. Biochem Int 1989;18:759-765.
-
(1989)
Biochem Int
, vol.18
, pp. 759-765
-
-
Portoukalian, J.1
David, M.J.2
Shen, X.3
Richard, M.4
Dubreuil, C.5
-
6
-
-
0023353680
-
Gangliosides shed by tumor cells enhance tumor formation in mice
-
Ladisch S, Kitada S, Hays EF: Gangliosides shed by tumor cells enhance tumor formation in mice. J Clin Invest 1987;79:1879-1882.
-
(1987)
J Clin Invest
, vol.79
, pp. 1879-1882
-
-
Ladisch, S.1
Kitada, S.2
Hays, E.F.3
-
7
-
-
0028890740
-
Human tumor gangliosides inhibit murine immune responses in vivo
-
Li R, Villacreses N, Ladisch S: Human tumor gangliosides inhibit murine immune responses in vivo. Cancer Res 1995;55:211-214.
-
(1995)
Cancer Res
, vol.55
, pp. 211-214
-
-
Li, R.1
Villacreses, N.2
Ladisch, S.3
-
8
-
-
0033213878
-
Tumor gangliosides inhibit the tumor specific immune response
-
McKallip R, Li R, Ladisch S: Tumor gangliosides inhibit the tumor specific immune response. J Immunol 1999;163:3718-3726.
-
(1999)
J Immunol
, vol.163
, pp. 3718-3726
-
-
McKallip, R.1
Li, R.2
Ladisch, S.3
-
9
-
-
0034616635
-
Influence of cellular ganglioside on tumor formation
-
Deng W, Li R, Ladisch S: Influence of cellular ganglioside on tumor formation. J Natl Cancer Inst 2000;92:912-917.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 912-917
-
-
Deng, W.1
Li, R.2
Ladisch, S.3
-
10
-
-
0026598475
-
Gangliosides suppress tumor necrosis factor production in human monocytes
-
Ziegler-Heitbrock HW, Kafferlein E, Haas JG, Meyer N, Strobel M, Weber C, Flieger D: Gangliosides suppress tumor necrosis factor production in human monocytes. J Immunol 1992;148:1753-1758.
-
(1992)
J Immunol
, vol.148
, pp. 1753-1758
-
-
Ziegler-Heitbrock, H.W.1
Kafferlein, E.2
Haas, J.G.3
Meyer, N.4
Strobel, M.5
Weber, C.6
Flieger, D.7
-
11
-
-
33646516647
-
Gangliosides trigger inflammatory responses via TLR4 in brain glia
-
Jou I, Lee JH, Park SY, Yoon HJ, Joe EH, Park EJ: Gangliosides trigger inflammatory responses via TLR4 in brain glia. Am J Pathol 2006;168:1619-1630.
-
(2006)
Am J Pathol
, vol.168
, pp. 1619-1630
-
-
Jou, I.1
Lee, J.H.2
Park, S.Y.3
Yoon, H.J.4
Joe, E.H.5
Park, E.J.6
-
13
-
-
0029900295
-
The tumor necrosis factor ligand and receptor families
-
Bazzoni F, Beutler B: The tumor necrosis factor ligand and receptor families. N Engl J Med 1996;334:1717-1725.
-
(1996)
N Engl J Med
, vol.334
, pp. 1717-1725
-
-
Bazzoni, F.1
Beutler, B.2
-
14
-
-
0035936797
-
The TNF and TNF receptor superfamilies: Integrating mammalian biology
-
Locksley RM, Killeen N, Lenardo MJ: The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 2001;104:487-501.
-
(2001)
Cell
, vol.104
, pp. 487-501
-
-
Locksley, R.M.1
Killeen, N.2
Lenardo, M.J.3
-
15
-
-
33947381060
-
Positive regulation of tumor necrosis factor alpha by ganglioside GM3 through Akt in mouse melanoma B16 cells
-
Wang P, Wu P, Zhang J, Sato T, Yamagata S, Yamagata T: Positive regulation of tumor necrosis factor alpha by ganglioside GM3 through Akt in mouse melanoma B16 cells. Biochem Biophys Res Commun 2007;356:438-443.
-
(2007)
Biochem Biophys Res Commun
, vol.356
, pp. 438-443
-
-
Wang, P.1
Wu, P.2
Zhang, J.3
Sato, T.4
Yamagata, S.5
Yamagata, T.6
-
17
-
-
23144467910
-
An expanding role for mTOR in cancer
-
Guertin DA, Sabatini DM: An expanding role for mTOR in cancer. Trends Mol Med 2005;11:353-361.
-
(2005)
Trends Mol Med
, vol.11
, pp. 353-361
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
18
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
Hara K, Maruki Y, Long X, Yoshino K, Oshiro N, Hidayat S, Tokunaga C, Avruch J, Yonezawa K: Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell 2002;110:177-189.
-
(2002)
Cell
, vol.110
, pp. 177-189
-
-
Hara, K.1
Maruki, Y.2
Long, X.3
Yoshino, K.4
Oshiro, N.5
Hidayat, S.6
Tokunaga, C.7
Avruch, J.8
Yonezawa, K.9
-
19
-
-
30644468118
-
mTOR and cancer: Reason for dancing at the crossroads?
-
Thomas GV: mTOR and cancer: reason for dancing at the crossroads? Curr Opin Genet Dev 2006;16:78-84.
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 78-84
-
-
Thomas, G.V.1
-
20
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N, Sonenberg N: Upstream and downstream of mTOR. Genes Dev 2004;18:1926-1945.
-
(2004)
Genes Dev
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
21
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signaling
-
Inoki K, Li Y, Zhu T, Wu J, Guan KL: TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signaling. Nat Cell Biol 2002;4:648-657.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
22
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B: SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 2006;127:125-137.
-
(2006)
Cell
, vol.127
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
Soto, N.4
Wei, S.5
Jung, S.Y.6
Huang, Q.7
Qin, J.8
Su, B.9
-
23
-
-
0037112363
-
RhoGDI2 is an invasion and metastasis suppressor gene in human cancer
-
Gildea JJ, Seraj MJ, Oxford G, Harding MA, Hampton GM, Moskaluk CA, Frierson HF, Conaway MR, Theodorescu D: RhoGDI2 is an invasion and metastasis suppressor gene in human cancer. Cancer Res 2002;62:6418-6423.
-
(2002)
Cancer Res
, vol.62
, pp. 6418-6423
-
-
Gildea, J.J.1
Seraj, M.J.2
Oxford, G.3
Harding, M.A.4
Hampton, G.M.5
Moskaluk, C.A.6
Frierson, H.F.7
Conaway, M.R.8
Theodorescu, D.9
-
24
-
-
0036191304
-
Rho GTPases in transformation and metastasis
-
Jaffe AB, Hall A: Rho GTPases in transformation and metastasis. Adv Cancer Res 2002;84:57-80.
-
(2002)
Adv Cancer Res
, vol.84
, pp. 57-80
-
-
Jaffe, A.B.1
Hall, A.2
-
25
-
-
84863698357
-
Ganglioside GD1a regulation of caveolin-1 and Stim1 expression in mouse FBJ cells: Augmented expression of caveolin-1 and stim1 in cells with increased GD1a content
-
Wang L, Takaku S, Wang P, Hu D, Hyuga S, Sato T, Yamagata S, Yamagata T: Ganglioside GD1a regulation of caveolin-1 and Stim1 expression in mouse FBJ cells: augmented expression of caveolin-1 and stim1 in cells with increased GD1a content. Glycoconj J 2006;23:303-315.
-
(2006)
Glycoconj J
, vol.23
, pp. 303-315
-
-
Wang, L.1
Takaku, S.2
Wang, P.3
Hu, D.4
Hyuga, S.5
Sato, T.6
Yamagata, S.7
Yamagata, T.8
-
26
-
-
23944439701
-
LY303511 (2-piperazinyl-8-phenyl-4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms
-
Kristof AS, Pacheco-Rodriguez G, Schremmer B, Moss J: LY303511 (2-piperazinyl-8-phenyl-4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms. J Pharmacol Exp Ther 2005;314:1134-1143.
-
(2005)
J Pharmacol Exp Ther
, vol.314
, pp. 1134-1143
-
-
Kristof, A.S.1
Pacheco-Rodriguez, G.2
Schremmer, B.3
Moss, J.4
-
28
-
-
33645801404
-
Opposite effects of wortmannin and 2-(4-morpholinyl)-8-phenyl-1(4H)-benzopyran- 4-one hydrochloride on toll-like receptor-mediated nitric oxide production: Negative regulation of nuclear factor-κB by phosphoinositide 3-kinase
-
Hazeki K, Kinoshita S, Matsumura T, Nigorikawa K, Kubo H, Hazeki O: Opposite effects of wortmannin and 2-(4-morpholinyl)-8-phenyl-1(4H)-benzopyran- 4-one hydrochloride on toll-like receptor-mediated nitric oxide production: negative regulation of nuclear factor-κB by phosphoinositide 3-kinase. Mol Pharmacol 2006;69:1717-1724.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 1717-1724
-
-
Hazeki, K.1
Kinoshita, S.2
Matsumura, T.3
Nigorikawa, K.4
Kubo, H.5
Hazeki, O.6
-
29
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering BM, Coffer PJ: Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 1995;376:599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
30
-
-
0029079275
-
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
Franke TF, Yang S, Chan TO, Datta K, Kazlauskas A, Morrison DK, Kaplan DR, Tsichlis PN: The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 1995;81:727-736.
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
Yang, S.2
Chan, T.O.3
Datta, K.4
Kazlauskas, A.5
Morrison, D.K.6
Kaplan, D.R.7
Tsichlis, P.N.8
-
31
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM: Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005;307:1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
32
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov DD, Ali SM, Sengupta S, Sheen JH, Hsu PP, Bagley AF, Markhard AL, Sabatini DM: Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell 2006;22:159-168.
-
(2006)
Mol Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
Markhard, A.L.7
Sabatini, D.M.8
-
33
-
-
23844468385
-
Endothelin axis is a target of the lung metastasis suppressor gene RhoGDI2
-
Titus B, Frierson HF Jr, Conaway M, Ching K, Guise T, Chirgwin J, Hampton G, Theodorescu D: Endothelin axis is a target of the lung metastasis suppressor gene RhoGDI2. Cancer Res 2005;65:7320-7327.
-
(2005)
Cancer Res
, vol.65
, pp. 7320-7327
-
-
Titus, B.1
Frierson Jr, H.F.2
Conaway, M.3
Ching, K.4
Guise, T.5
Chirgwin, J.6
Hampton, G.7
Theodorescu, D.8
-
34
-
-
45549097766
-
Ganglioside GM3 positively regulates Arhgdib, a Rho GTPase regulator, to suppress anchorage-independent growth via PI3K/AKT/mTOR pathway in mouse melanoma B16 cells
-
In preparation
-
Wang P, Wu P, Zhang J, Sato T, Yamagat S, Yamagata T: Ganglioside GM3 positively regulates Arhgdib, a Rho GTPase regulator, to suppress anchorage-independent growth via PI3K/AKT/mTOR pathway in mouse melanoma B16 cells. In preparation.
-
-
-
Wang, P.1
Wu, P.2
Zhang, J.3
Sato, T.4
Yamagat, S.5
Yamagata, T.6
|