Cyclin E and SV40 small t antigen cooperate to bypass quiescence and contribute to transformation by activating CDK2 in human fibroblasts

Journal of Biological Chemistry

Volumn 283, Issue 17, 2008, Pages 11280-11292

  Sotillo, Elena ^a   Garriga, Judit ^a   Kurimchak, Alison ^a   Graña, Xavier ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; CELL CULTURE; CHEMICAL ACTIVATION; DNA; FIBROBLASTS; GENES; MAMMALS; NUCLEIC ACIDS; ONCOGENIC VIRUSES; ONCOLOGY; ORGANIC ACIDS; STEELMAKING;

CDK INHIBITORS; CELL CYCLE ENTRIES; CELL LINES; CYCLIN E; DNA SYNTHESIS; ECTOPIC EXPRESSIONS; FOCI FORMATIONS; HUMAN FIBROBLASTS; HUMAN TUMORS; LIMITING STEPS; MITOGEN; MITOGENIC; NORMAL HUMAN FIBROBLASTS; OVEREXPRESSION; PRIMARY CELLS; TUMOR CELLS;

TUMORS;

CYCLIN DEPENDENT KINASE 2; CYCLIN E; THREONINE; VIRUS SMALL T ANTIGEN; CDK2 PROTEIN, HUMAN; DNA; RECOMBINANT PROTEIN; VIRUS T ANTIGEN;

ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FIBROBLAST; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SIMIAN VIRUS 40; TUMOR CELL; BIOLOGICAL MODEL; CHEMISTRY; CULTURE TECHNIQUE; GENE EXPRESSION REGULATION; METABOLISM; PHOSPHORYLATION; TIME;

MAMMALIA;

ANTIGENS, VIRAL, TUMOR; CELL CULTURE TECHNIQUES; CELL CYCLE; CELL PROLIFERATION; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; DNA; ENZYME ACTIVATION; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; MODELS, BIOLOGICAL; PHOSPHORYLATION; RECOMBINANT PROTEINS; TIME FACTORS;

EID: 45549088264     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M709055200     Document Type: Article

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