A novel T cell-regulated mechanism modulating allergen-induced airways hyperreactivity in BALB/C mice independently of IL-4 and IL-5

Journal of Immunology

Volumn 161, Issue 3, 1998, Pages 1501-1509

  Hogan, Simon P ^a   Matthaei, Klaus I ^a   Young, Janine M ^a   Koskinen, Aulikki ^a   Young, Ian G ^a   Foster, Paul S ^a  

^a Biology and Environment   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CD4 ANTIGEN; OKT 4; RECOMBINANT INTERLEUKIN 4; RECOMBINANT INTERLEUKIN 5;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EOSINOPHILIA; HISTOPATHOLOGY; IMMUNOREGULATION; INHIBITION KINETICS; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; T LYMPHOCYTE ACTIVATION;

ALLERGENS; ANIMALS; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; CD4-POSITIVE T-LYMPHOCYTES; INFLAMMATION; INTERLEUKIN-4; INTERLEUKIN-5; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; OVALBUMIN; T-LYMPHOCYTES;

EID: 0032145438     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Robinson, D. S., Q. Hamid, S. Ying, A. Tsicopoulos, J. Barkans, A. M. Bentley, C. Corrigan, S. R. Durham, and A. B. Kay. 1992. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med. 326:298.
2. Bradley, B. L., M. Azzawi, M. Jacobson, B. Assoufi, J. V. Collins, A. M. Irani, L. B. Schwanz, S. R. Durham, P. K. Jeffery, and A. B. Kay, 1991. Eosinophils, T-lymphocytes, mast cells, neutrophils and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness. J. Allergy Clin. Immunol. 88:661.
3. Robinson, D. S., S. Ying, A. M. Bentley, Q. Meng, J. North, S. R. Durham, A. B. Kay, and Q. Hamid. 1993. Relationships among numbers of bronchoaiveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma. J. Allergy Clin. Immunol. 92:397.
4. Walker, C., E. Bode, L. Boer, T. T. Hansel, K. Blaser, and J. C. Virchow, Jr. 1992. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am. Rev. Respir. Dis. 146:109.
5. Walker, C., J. C. Virchow, Jr., P. L. Bruijnzeel, and K. Blaser. 1991. T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma. J. Immunol. 146:1829.
6. + T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma. J. Allergy Clin. Immunol. 92:313.
7. Hamid, Q., M. Azzawi, S. Ying, R. Moqbel, A. J. Wardlaw, C. J. Corrigan, B. Bradley, S. R. Durham, J. V. Collins, P. K. Jeffery, D. J. Quint, and A. B. Kay. 1991. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J. Clin. Invest. 87:1541.
8. De Monchy, J. G., H. F. Kauffman, P. Venge, G. H. Koeter, H. M. Jansen, H. J. Sluiter, and K. de Vries. 1985. Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions. Am. Rev. Respir. Dis. 131:373.
9. Wardlaw, A. J., S. Dunnette, G. J. Gleich, J. V. Collins, and A. B. Kay. 1988. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity. Am. Rev. Respir. Dis. 137.-62.
10. Beasley, R., W. R. Roche, J. A. Roberts, and S. T. Holgate. 1989. Cellular events in the bronchi in mild asthma and after bronchial provocation. Am. Rev. Respir. Dis. 139:806.
11. Azzawi, M., B. Bradley, P. K. Jeffery, A. J. Frew, A. J. Wardlaw, G. Knowles, B. Assoufi, J. V. Collins, S. Durham, and A. B. Kay. 1990. Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am. Rev. Respir. Dis. 142:1407.
12. Ohashi, Y., S. Motojima, T. Fukuda, and S. Makino. 1992. Airway hyperresponsiveness, increased intracellular spaces of bronchial epithelium, and increased infiltration of eosinophils and lymphocytes in bronchial mucosa in asthma. Am. Rev. Respir. Dis. 145:1469.
13. Broide, D. H., G. J. Gleich, A. J. Cuomo, D. A. Coburn, E. C. Federman, L. B. Schwartz, and S. I. Wasserman. 1991. Evidence of ongoing mast cell and eosinophil degranulation in symptomatic asthma airway. J. Allergy Clin. Immunol. 88:637.
14. + T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea. Am. Rev. Respir. Dis. 146:374.
15. Mauser, P. S., A. Pitman, A. Witt, X. Fernandez, J. Zurcher, T. Kung, H. Jones, A. S. Watnick, R. W. Egan, W. Kreutner, and G. K. Adams III. 1993. Inhibitory effect of the TRFK-5 anti-IL-5 antibody in a guinea pig model of asthma. Am. Rev. Respir. Dis. 148:1623.
16. Milne, A. A., and P. J. Piper. 1994. Effects of interleukin-5 inhibition on antigen-induced airway hyperresponsiveness and cell accumulation in guinea pigs. Ann. N. Y. Acad. Sci. 725:282.
17. Brusselle, G. G., J. C. Kips, J. H. Tavemier, J. G. van-der-Heyden, C. A. Cuvelier, R. A. Pauwels, and H. Bluethmann. 1994. Attenuation of allergic airway inflammation in IL-4-deficient mice. Clin. Exp. Allergy 24:73.
18. Kennedy, J. D., C. A. Hatfield, S. F. Fidler, G. E. Winterrowd, J. V. Haas, J. E. Chin, and I. M. Richards. 1995. Phenotypic characterization of T lymphocytes emigrating into lung tissue and the airway lumen after antigen inhalation in sensitized mice. Am. J. Respir. Cell. Mol. Biol. 12:613.
19. Finkelman, F. D., I. M. Katona, J. F. Urban, J. Holmes, J. Ohara, A. S. Tung, J. G. Sample, and W. E. Paul. 1988. IL-4 is required to generate and sustain in vivo IgE responses. J. Immunol. 141:2335.
20. Swain, S. L., A. D. Weinberg, M. English, and G. Hutson. 1990. IL-4 directs the development of Th2 effectors. J. Immunol. 145:3796.
21. Lopez, A. F., C. J. Sanderson, J. R. Gamble, H. D. Campbell, I. G. Young, and M. A. Vadas: 1988. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J. Exp. Med. 167:219.
22. Yamaguchi, Y., Y. Hayashi, Y. Sugama, Y. Miura, T. Kasahara, S. Kitamura, M. Torisu, S. Mita, A. Tominaga, K. Takatsu, and T. Suda. 1988. Highly purified murine interleukin-5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. J. Exp. Med. 167:1737.
23. Clutterbuck, E. J., E. M. Hirst, and C. J. Sanderson. 1989. Human interleukin 5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparisons and interactions with IL-1, IL-3, IL-6 and GM-CSF. Blood 73:1504.
24. + B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 4:15.
25. Foster, P. S., S. P. Hogan, A. J. Ramsay, K. I. Matthaei, and I. G. Young. 1996. IL-5 deficiency abolishes eosinophilia, airways hyperreactivity and lung damage in a mouse asthma model. J. Exp. Med. 183:195.
26. Hogan, S. P., A. Mould, H. Kikutani, A. J. Ramsay, and P. S. Foster. 1997. Aeroallergen-induced eosinophilic inflammation, lung damage and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J. Clin. Invest. 99:1329.
27. Corry, D. B., H. G. Folkesson, M. L. Warnock, D. J. Erle, M. A. Matthay, J. P. Wiener-Kronish, and R. M. Locksley. 1996. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J. Exp. Med. 183:109.
28. Eum, S. Y., S. Haile, J. Lefort, M. Huerre, and B. B. Vargaftig. 1995. Eosinophil recruitment into the respiratory epithelium following antigenic challenge in hyper-IgE mice is accompanied by interleukin 5-dependent bronchial hyperresponsiveness. Proc. Natl. Acad. Sci. USA 92:12290.
29. Yamaguchi, Y., H. Nagai, H. Tanaka, M. Tsujimoto and N. Tsuroka. 1994. Time course study for antigen-induced airways hyperreactivity and the effect of soluble IL-5 receptor. Life Sci. 54:L471.
30. Djukanovic, R., J. W. Wilson, K. M. Britten, S. J. Wilson, A. F. Walls, W. R. Roche, P. H. Howarth, and S. T. Holgate. 1990. Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry. Am. Rev. Respir. Dis. 142: 863.
31. Coyle, A. J., K. Wagner, C. Bertrand, S. Tsuyuki, J. Bews, and C. Heusser. 1996. Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: inhibition by a nonanaphylactogenic anti-IgE antibody. J. Exp. Med. 183:1303.
32. Ishida, K., R. J. Thompson, L. L. Beattie, B. Wiggs, and R. R. Schellenberg. 1990. Inhibition of antigen-induced airway hyperresponsiveness, but not acute hypoxia nor airway eosinophilia, by an antagonist of platelet-activating factor. J. Immunol. 144:3907.
33. Mapp, C. E., P. Boschetto, P. G. F. Milani, F. Pivirotto, V. Tegazzin, L. M. Fabri, and E. Zocca. 1987. Pathogenesis of late asthmatic reactions induced by exposure to isocyanates. Clin. Respir. Physiol. 23:583.
34. Henderson Jr, W. R. D. B. Lewis, R. K. Albert, Y. Zhang, W. J. E. Lamm, G. K. S. Chiang, F. Jones, P. Erikson, Y. Tien, M. Jonas, and E. Y. Chi. 1996. The Importance of leukotrienes in airway inflammation in a mouse model of asthma. J. Exp. Med. 184:1483.
35. Hamelmann, E., A. T. Vella, A. Oshiba, J. W. Kappler, P. Marrack, and E. W. Gelfand. Allergic airways sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. Proc. Natl. Acad. Sci. USA 94:1350.
36. Drazen, J. M., J. P. Arm, and K. F.Austen. 1996. Sorting out the cytokines of asthma. J. Exp. Med. 183:1.
37. Hunt, J. E., R. L. Stevens, K. F. Austen, J. Zhang, Z. Xia, and N. Ghildyal. 1996. Natural disruption of the mouse mast cell protease 7 gene in the C57BL/6 mouse. J. Biol. Chem. 5:2851.
38. Noben-Trauth, N., P. Kropf, and I. Muller. 1996. Susceptibility to Leishmania major infection in Interleukin-4-deficient mice. Science 271:987.
39. Hamelmann, E., A. Oshiba, J. Loader, G. L. Larsen, G. Gleich, and E. W. Gelfand. 1997. Anti-interleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airways sensitization. Am. Rev. Resp. Crit. Care Med. 155:819.
40. Hogan, S. P., A. Koskinen, and P. S. Foster. 1997. IL-5 and eosinophils contribute to the induction of airways damage and bronchial hyperreactivity during allergic airways inflammation in BALB/c mice. Immunol. Cell Biol. 75:284.
41. Joos, G. F., J. C. Kipps, and R. A. Pauwels. 1993. Direct and indirect bronchial responsiveness. Respir. Med. 87:31.
42. Chapman, I. D., A. Foster, and J. Morely. 1993. The relationship between inflammation and hyperreactivity of the airways in asthma. Clin. Exp. Allergy 23: 168.
43. Frick, W. E., J. B. Sedgwick, and W. W. Busse. 1989. The appearance of hypodense eosinophils in antigen-dependent late phase asthma. Am. Rev. Respir. Dis. 139:1401.
44. Gleich, G. J., N. A. Flavahan, T. Fujisawa, and P. M. Vanhoutte. 1988. Eosinophil as a mediator of damage to respiratory epithelium: a model for bronchial hyperreactivity. J. Allergy Clin. Immunol. 81:776.
45. Bousquet, J., P. Chanez, J. Y. Lacoste, G. Barneon, N. Ghavanian, I, Enander, P. Venge, S. Ahlstedt, J. Simony Lafontaine, P. Godard, and F. B. Michel. 1990. Eosinophilic inflammation in asthma. N. Engl. J. Med. 323:1033.
46. Lee, J. J., M. P. McGarry, S. C. Farmer, K. L. Denzler, K. A. Larson, P. E. Carrigan, I. E. Brenneise, M. A. Horton, A. Hackzu, E. W. Gelfand, G. D. Leikauf, and N. A. Lee. Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomic of asthma. J. Exp. Med. 185:2143.
47. Rankin, J. A., D. E. Picarella, G. P. Geba, U. A. Temann, B. Prasad, B. Dicosmo. A. Tarallo, B. Stripp, J. Whitsett, and R. A. Flavell. 1996. Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: Lymphocytic and eosinophilic inflammation with airway hyperreactivity. Proc. Natl. Acad. Sci. USA 93:7821.
48. + T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea. Am. Rev. Respir. Dis. 146:374.
49. + T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am. J. Respir. Cell Mol. Biol. 10:587.
50. + T cells in Brown Norway rats. J. Clin. Invest. 96:1303.
51. De Sanctis, G. T., A. Itoh, F. H. Y. Green, S. Qin, T. Kimura, J. K., Grobholz, T. R. Martin, T. Maki, and J. M. Drazen. 1997. T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice. Nat. Med. 3:460.