메뉴 건너뛰기




Volumn 10, Issue 25, 2004, Pages 3081-3093

Immunomodulatory effects of macrolides in the lung: Lessons from in-vitro and in-vivo models

Author keywords

Cytokines; Immune response; Leukocytes; Lung inflammation; Macrolides

Indexed keywords

AZITHROMYCIN; BAFILOMYCIN; CLARITHROMYCIN; CYCLOSPORIN A; DIRITHROMYCIN; ERYTHROMYCIN; HMR 3004; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; JOSAMYCIN; MACROLIDE; MIDECAMYCIN; NITRIC OXIDE; PHOSPHOLIPASE; PROSTAGLANDIN E2; RAPAMYCIN; RIFAMPICIN; ROKITAMYCIN; ROXITHROMYCIN; SPIRAMYCIN; STEROID; TACROLIMUS; TELITHROMYCIN; TILMICOSIN; TROLEANDOMYCIN; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

EID: 4544273263     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612043383430     Document Type: Review
Times cited : (44)

References (111)
  • 1
    • 0024336748 scopus 로고
    • Interaction of azithromycin and human phagocytic cells. Uptake of the antibiotic and the effect on the survival of ingested bacteria in phagocytes
    • Wildfeuer AH, Laufen D, Muller-Wening O, Haferkamp. Interaction of azithromycin and human phagocytic cells. Uptake of the antibiotic and the effect on the survival of ingested bacteria in phagocytes. Arzneimittelforschung 1989; 39: 755.
    • (1989) Arzneimittelforschung , vol.39 , pp. 755
    • Wildfeuer, A.H.1    Laufen, D.2    Muller-Wening, O.3    Haferkamp, A.4
  • 2
    • 0024566566 scopus 로고
    • Erythromycin and roxithromycin potentiate human neutrophil locomotion in vitro by inhibition of leukoattractant-activated superoxide generation and autooxidation
    • Anderson R. Erythromycin and roxithromycin potentiate human neutrophil locomotion in vitro by inhibition of leukoattractant-activated superoxide generation and autooxidation. J Infect Dis 1989; 159: 966.
    • (1989) J. Infect. Dis. , vol.159 , pp. 966
    • Anderson, R.1
  • 3
    • 0025848083 scopus 로고
    • In vitro and ex vivo effects of recent and new macrolide antibiotics on chemotaxis of human polymorphonuclear leukocytes
    • Torre D, Broggini M, Botta V, Sampietro C, Busarello R, Garberi C. In vitro and ex vivo effects of recent and new macrolide antibiotics on chemotaxis of human polymorphonuclear leukocytes. J Chemother 1991; 3: 236.
    • (1991) J. Chemother. , vol.3 , pp. 236
    • Torre, D.1    Broggini, M.2    Botta, V.3    Sampietro, C.4    Busarello, R.5    Garberi, C.6
  • 4
    • 0024423069 scopus 로고
    • Comparison of the in-vitro effect of several macrolides on the oxidative burst of human neutrophils
    • Labro MT, el Benna J, Babin-Chevaye C. Comparison of the in-vitro effect of several macrolides on the oxidative burst of human neutrophils. J Antimicrob Chemother 1989; 24: 561.
    • (1989) J. Antimicrob. Chemother. , vol.24 , pp. 561
    • Labro, M.T.1    el Benna, J.2    Babin-Chevaye, C.3
  • 5
    • 0033624342 scopus 로고    scopus 로고
    • Erythromycin inhibits beta2-integrins (CD11b/CD18) expression, interleukin-8 release and intracellular oxidative metabolism in neutrophils
    • Lin HC, Wang CH, Liu CY, Yu CT, Kuo HP. Erythromycin inhibits beta2-integrins (CD11b/CD18) expression, interleukin-8 release and intracellular oxidative metabolism in neutrophils. Respir Med 2000; 94: 654.
    • (2000) Respir. Med. , vol.94 , pp. 654
    • Lin, H.C.1    Wang, C.H.2    Liu, C.Y.3    Yu, C.T.4    Kuo, H.P.5
  • 6
    • 0029114526 scopus 로고
    • Effect of roxithromycin on peripheral neutrophil adhesion molecules in patients with chronic lower respiratory tract disease
    • Kusano SJ, Kadota S, Kohno K, Iida K, Kawakami T, Morikawa, et al. Effect of roxithromycin on peripheral neutrophil adhesion molecules in patients with chronic lower respiratory tract disease. Respiration 1995; 62: 217.
    • (1995) Respiration , vol.62 , pp. 217
    • Kusano, S.J.1    Kadota, S.2    Kohno, K.3    Iida, K.4    Kawakami, T.5    Morikawa, A.6
  • 7
    • 0030063950 scopus 로고    scopus 로고
    • Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells
    • Matsuoka NK, Eguchi A, Kawakami M, Tsuboi Y, Kawabe T, Aoyagi S, et al. Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells. Clin Exp Immunol 1996; 104: 501.
    • (1996) Clin. Exp. Immunol. , vol.104 , pp. 501
    • Matsuoka, N.K.1    Eguchi, A.2    Kawakami, M.3    Tsuboi, Y.4    Kawabe, T.5    Aoyagi, S.6
  • 9
    • 0030178838 scopus 로고    scopus 로고
    • Comparison of various macrolides on stimulation of human neutrophil degranulation in vitro
    • Abdelghaffar HD, Vazifeh, Labro MT. Comparison of various macrolides on stimulation of human neutrophil degranulation in vitro. J Antimicrob Chemother 1996; 38: 81.
    • (1996) J. Antimicrob. Chemother. , vol.38 , pp. 81
    • Abdelghaffar, H.D.1    Vazifeh Labro, M.T.2
  • 10
    • 0031572435 scopus 로고    scopus 로고
    • Erythromycin A-derived macrolides modify the functional activities of human neutrophils by altering the phospholipase D-phosphatidate phosphohydrolase transduction pathway: L-cladinose is involved both in alterations of neutrophil functions and modulation of this transductional pathway
    • Abdelghaffar HD, Vazifeh, Labro MT. Erythromycin A-derived macrolides modify the functional activities of human neutrophils by altering the phospholipase D-phosphatidate phosphohydrolase transduction pathway: L-cladinose is involved both in alterations of neutrophil functions and modulation of this transductional pathway. J Immunol 1997; 159: 3995.
    • (1997) J. Immunol. , vol.159 , pp. 3995
    • Abdelghaffar, H.D.1    Vazifeh Labro, M.T.2
  • 12
    • 0031879813 scopus 로고    scopus 로고
    • Interactions between HMR 3647, a new ketolide, and human polymorphonuclear neutrophils
    • Vazifeh DA, Preira A, Bryskier, Labro MT. Interactions between HMR 3647, a new ketolide, and human polymorphonuclear neutrophils. Antimicrob Agents Chemother 1998; 42: 1944.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 1944
    • Vazifeh, D.A.1    Preira, A.2    Bryskier, A.3    Labro, M.T.4
  • 13
    • 0028903792 scopus 로고
    • Erythromycin shortens neutrophil survival by accelerating apoptosis
    • Aoshiba KA, Nagai, Konno K. Erythromycin shortens neutrophil survival by accelerating apoptosis. Antimicrob Agents Chemother 1995; 39: 872.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 872
    • Aoshiba, K.A.1    Nagai Konno, K.2
  • 14
    • 0033808917 scopus 로고    scopus 로고
    • The effects of erythromycin on human peripheral neutrophil apoptosis
    • Inamura KN, Ohta S, Fukase N, Kasajima, Aoyagi M, The effects of erythromycin on human peripheral neutrophil apoptosis. Rhinology 2000; 38: 124.
    • (2000) Rhinology , vol.38 , pp. 124
    • Inamura, K.N.1    Ohta, S.2    Fukase, N.3    Kasajima, A.4    Aoyagi, M.5
  • 16
    • 0031839437 scopus 로고    scopus 로고
    • Effect of a 17-member azalide on tumor cell growth
    • Grdisa M, Lopotar N, Pavelic K. Effect of a 17-member azalide on tumor cell growth. Chemotherapy 1998; 44: 331.
    • (1998) Chemotherapy , vol.44 , pp. 331
    • Grdisa, M.1    Lopotar, N.2    Pavelic, K.3
  • 17
    • 0029658654 scopus 로고    scopus 로고
    • Neutrophil chemotactic activity in cryptogenic organizing pneumonia and the response to erythromycin
    • Hotta M. Neutrophil chemotactic activity in cryptogenic organizing pneumonia and the response to erythromycin. Kurume Med J 1996; 43: 207.
    • (1996) Kurume Med. J. , vol.43 , pp. 207
    • Hotta, M.1
  • 19
    • 0031816305 scopus 로고    scopus 로고
    • Anti-inflammatory benefits of tilmicosin in calves with Pasteurella haemolytica-infected lungs
    • Chin AC, Morck DW, Merrill JK, Ceri H, Olson ME, Read RR, et al. Anti-inflammatory benefits of tilmicosin in calves with Pasteurella haemolytica-infected lungs. Am J Vet Res 1998; 59: 765.
    • (1998) Am. J. Vet. Res. , vol.59 , pp. 765
    • Chin, A.C.1    Morck, D.W.2    Merrill, J.K.3    Ceri, H.4    Olson, M.E.5    Read, R.R.6
  • 20
    • 0038173761 scopus 로고    scopus 로고
    • The effects of danofloxacin and tilmicosin on neutrophil function and lung consolidation in beef heifer calves with induced Pasteurella (Mannheimia) haemolytica pneumonia
    • Fajt VR, Apley MD, Roth JA, Frank DE, Brogden KA, Skogerboe TL, et al. The effects of danofloxacin and tilmicosin on neutrophil function and lung consolidation in beef heifer calves with induced Pasteurella (Mannheimia) haemolytica pneumonia. J Vet Pharmacol Ther 2003; 26: 173.
    • (2003) J. Vet. Pharmacol. Ther. , vol.26 , pp. 173
    • Fajt, V.R.1    Apley, M.D.2    Roth, J.A.3    Frank, D.E.4    Brogden, K.A.5    Skogerboe, T.L.6
  • 21
    • 0023949018 scopus 로고
    • Activities of human alveolar macrophages (HAMs). Note 1: Observations on phagocytosis and bacterial killing in the presence of miocamycin
    • Capelli A, Capelli O, Azzolini L, Richeldi L, Prandi E, Velluti G. Activities of human alveolar macrophages (HAMs). Note 1: Observations on phagocytosis and bacterial killing in the presence of miocamycin. Chemioterapia 1988; 7: 89.
    • (1988) Chemioterapia , vol.7 , pp. 89
    • Capelli, A.1    Capelli, O.2    Azzolini, L.3    Richeldi, L.4    Prandi, E.5    Velluti, G.6
  • 23
    • 0029347155 scopus 로고
    • Effects of bafilomycin A1 on cytosolic pH of sheep alveolar and peritoneal macrophages: Evaluation of the pH-regulatory role of plasma membrane V-ATPases
    • Heming TA, Traber DL, Hinder F, Bidani A. Effects of bafilomycin A1 on cytosolic pH of sheep alveolar and peritoneal macrophages: evaluation of the pH-regulatory role of plasma membrane V-ATPases. J Exp Biol 1995; 198 (Pt 8): 1711.
    • (1995) J. Exp. Biol. , vol.198 , Issue.PART 8 , pp. 1711
    • Heming, T.A.1    Traber, D.L.2    Hinder, F.3    Bidani, A.4
  • 24
    • 0030878167 scopus 로고    scopus 로고
    • Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: Role of alveolar macrophage activation and cytokine release
    • Chen B, Jiang L, Zhao W, Yu R, Hou XM. Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release. Respirology 1997; 2: 151.
    • (1997) Respirology , vol.2 , pp. 151
    • Chen, B.1    Jiang, L.2    Zhao, W.3    Yu, R.4    Hou, X.M.5
  • 25
    • 0033487570 scopus 로고    scopus 로고
    • The effect of erythromycin on NF-kappa B activation and cytokines mRNA expression in bleomycin-induced pulmonary fibrosis in rats
    • Li Y, He B, Wang H. [The effect of erythromycin on NF-kappa B activation and cytokines mRNA expression in bleomycin-induced pulmonary fibrosis in rats]. Zhonghua Jie He He Hu Xi Za Zhi 1999; 22: 725.
    • (1999) Zhonghua Jie He He Hu Xi Za Zhi , vol.22 , pp. 725
    • Li, Y.1    He, B.2    Wang, H.3
  • 26
    • 0032933562 scopus 로고    scopus 로고
    • Effects of erythromycin and its derivatives on interleukin-8 release by human bronchial epithelial cell line BEAS-2B cells
    • Sunazuka T, Takizawa H, Desaki M, Suzuki K, Obata R, Otoguro K, et al. Effects of erythromycin and its derivatives on interleukin-8 release by human bronchial epithelial cell line BEAS-2B cells. J Antibiot (Tokyo) 1999; 52: 71.
    • (1999) J. Antibiot. (Tokyo) , vol.52 , pp. 71
    • Sunazuka, T.1    Takizawa, H.2    Desaki, M.3    Suzuki, K.4    Obata, R.5    Otoguro, K.6
  • 28
    • 0033198146 scopus 로고    scopus 로고
    • Macrolide antibiotics protect against immune complex-induced lung injury in rats: Role of nitric oxide from alveolar macrophages
    • Tamaoki J, Kondo M, Kohri K, Aoshiba K, Tagaya E, Nagai A. Macrolide antibiotics protect against immune complex-induced lung injury in rats: role of nitric oxide from alveolar macrophages. J Immunol 1999; 163: 2909.
    • (1999) J. Immunol. , vol.163 , pp. 2909
    • Tamaoki, J.1    Kondo, M.2    Kohri, K.3    Aoshiba, K.4    Tagaya, E.5    Nagai, A.6
  • 29
    • 0033979366 scopus 로고    scopus 로고
    • Macrolide antibiotics inhibit nitric oxide generation by rat pulmonary alveolar macrophages
    • Kohri K, Tamaoki J, Kondo M, Aoshiba K, Tagaya E, Nagai A. Macrolide antibiotics inhibit nitric oxide generation by rat pulmonary alveolar macrophages. Eur Respir J 2000; 15: 62.
    • (2000) Eur. Respir. J. , vol.15 , pp. 62
    • Kohri, K.1    Tamaoki, J.2    Kondo, M.3    Aoshiba, K.4    Tagaya, E.5    Nagai, A.6
  • 30
    • 0035655178 scopus 로고    scopus 로고
    • Characterization of CD44 expressed on alveolar macrophages in patients with diffuse panbronchiolitis
    • Katoh S, Matsubara Y, Taniguchi H, Fukushima K, Mukae H, Kadota J, et al. Characterization of CD44 expressed on alveolar macrophages in patients with diffuse panbronchiolitis. Clin Exp Immunol 2001; 126: 545.
    • (2001) Clin. Exp. Immunol. , vol.126 , pp. 545
    • Katoh, S.1    Matsubara, Y.2    Taniguchi, H.3    Fukushima, K.4    Mukae, H.5    Kadota, J.6
  • 31
    • 0028886393 scopus 로고
    • Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epitheliall cells
    • Khair OA, Devalia JL, Abdelaziz MM, Sapsford RJ, Davies RJ. Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epitheliall cells. Eur Respir J 1995; 8: 1451.
    • (1995) Eur. Respir. J. , vol.8 , pp. 1451
    • Khair, O.A.1    Devalia, J.L.2    Abdelaziz, M.M.3    Sapsford, R.J.4    Davies, R.J.5
  • 32
    • 0029126897 scopus 로고
    • Erythromycin suppresses interleukin 6 expression by human bronchial epithelial cells: A potential mechanism of its anti-inflammatory action
    • Takizawa H, Desaki M, Ohtoshi T, Kikutani T, Okazaki H, Sato M, et al. Erythromycin suppresses interleukin 6 expression by human bronchial epithelial cells: a potential mechanism of its anti-inflammatory action. Biochem Biophys Res Commun 1995; 210: 781.
    • (1995) Biochem. Biophys. Res. Commun. , vol.210 , pp. 781
    • Takizawa, H.1    Desaki, M.2    Ohtoshi, T.3    Kikutani, T.4    Okazaki, H.5    Sato, M.6
  • 33
    • 0031618813 scopus 로고    scopus 로고
    • Effect of macrolides on 1L-8 gene expression by cultured airway epithelial cells
    • Abe S, Nakamura H, Kato S, Tomoike H, Takeda H. [Effect of macrolides on 1L-8 gene expression by cultured airway epithelial cells]. Jpn J Antibiot 1998; 51 Suppl: 120.
    • (1998) Jpn. J. Antibiot. , vol.51 , Issue.SUPPL. , pp. 120
    • Abe, S.1    Nakamura, H.2    Kato, S.3    Tomoike, H.4    Takeda, H.5
  • 34
    • 0034035777 scopus 로고    scopus 로고
    • Interleukin-8 gene repression by clarithromycin is mediated by the activator protein-1 binding site in human bronchial epithelial cells
    • Abe S, Nakamura H, Inoue S, Takeda H, Saito H, Kato S, et al. Interleukin-8 gene repression by clarithromycin is mediated by the activator protein-1 binding site in human bronchial epithelial cells. Am J Respir Cell Mol Biol 2000; 22: 51.
    • (2000) Am. J. Respir. Cell Mol. Biol. , vol.22 , pp. 51
    • Abe, S.1    Nakamura, H.2    Inoue, S.3    Takeda, H.4    Saito, H.5    Kato, S.6
  • 35
    • 0034614474 scopus 로고    scopus 로고
    • Erythromycin suppresses nuclear factor-kappaB and activator protein-1 activation in human bronchial epithelial cells
    • Desaki M, Takizawa H, Ohtoshi T, Kasama T, Kobayashi K, Sunazuka T, et al. Erythromycin suppresses nuclear factor-kappaB and activator protein-1 activation in human bronchial epithelial cells. Biochem Biophys Res Commun 2000; 267: 124.
    • (2000) Biochem. Biophys. Res. Commun. , vol.267 , pp. 124
    • Desaki, M.1    Takizawa, H.2    Ohtoshi, T.3    Kasama, T.4    Kobayashi, K.5    Sunazuka, T.6
  • 36
    • 0035257559 scopus 로고    scopus 로고
    • Interferon-gamma activates outwardly rectifying chloride channels in the human bronchial epithelial cell line BEAS-2B
    • Ge N, Nakamura Y, Nakaya Y, Sone S. Interferon-gamma activates outwardly rectifying chloride channels in the human bronchial epithelial cell line BEAS-2B. J Med Invest 2001; 48: 97.
    • (2001) J. Med. Invest. , vol.48 , pp. 97
    • Ge, N.1    Nakamura, Y.2    Nakaya, Y.3    Sone, S.4
  • 37
    • 0035790134 scopus 로고    scopus 로고
    • Effect of azithromycin on cytokine production in human bronchial epithelial cell line, BEAS-213
    • Kato T, Yamada M, Kohara Y, Ikekita M, Yonmiya T. Effect of azithromycin on cytokine production in human bronchial epithelial cell line, BEAS-213. Japan J Antibiot 2001; 54 Suppl C: 83.
    • (2001) Japan J. Antibiot. , vol.54 , Issue.SUPPL. C , pp. 83
    • Kato, T.1    Yamada, M.2    Kohara, Y.3    Ikekita, M.4    Yonmiya, T.5
  • 39
    • 0029096003 scopus 로고
    • Effect on Pseudomonas aeruginosa alginate expression of direct plating and culture of fresh cystic fibrosis sputum on to pseudomonas isolation agar containing subinhibitory concentrations of roxithromycin and rifampicin
    • Dupont MJ, Lapointe JR. Effect on Pseudomonas aeruginosa alginate expression of direct plating and culture of fresh cystic fibrosis sputum on to pseudomonas isolation agar containing subinhibitory concentrations of roxithromycin and rifampicin. J Antimicrob Chemother 1995; 36: 231.
    • (1995) J. Antimicrob. Chemother. , vol.36 , pp. 231
    • Dupont, M.J.1    Lapointe, J.R.2
  • 40
    • 0031083664 scopus 로고    scopus 로고
    • Actions of macrolide antibiotics on alginate production by Pseudomonas aeruginosa
    • Kobayashi O, Ota M, Watanabe H, Kobayashi H. Actions of macrolide antibiotics on alginate production by Pseudomonas aeruginosa. Jpn J Antibiot 1997; 50 Suppl: 95.
    • (1997) Jpn. J. Antibiot. , vol.50 , Issue.SUPPL. , pp. 95
    • Kobayashi, O.1    Ota, M.2    Watanabe, H.3    Kobayashi, H.4
  • 41
    • 0035790354 scopus 로고    scopus 로고
    • Effect of macrolide antibiotics on MUC5AC production in human bronchial epithelial cells
    • Takeyama K, Tamaoki A, Kondo M, Aoshiba K, Nakata J, Isono K, et al. Effect of macrolide antibiotics on MUC5AC production in human bronchial epithelial cells. Jpn J Antibiot 2001; 54 Suppl C: 52.
    • (2001) Jpn. J. Antibiot. , vol.54 , Issue.SUPPL. C , pp. 52
    • Takeyama, K.1    Tamaoki, A.2    Kondo, M.3    Aoshiba, K.4    Nakata, J.5    Isono, K.6
  • 44
    • 0035860292 scopus 로고    scopus 로고
    • Gene expression profiles of human small airway epithelial cells treated with low doses of 14- and 16-membered macrolides
    • Yamanaka Y, Tamari M, Nakahata T, Nakamura Y. Gene expression profiles of human small airway epithelial cells treated with low doses of 14- and 16-membered macrolides. Biochem Biophys Res Commun 2001; 287: 198.
    • (2001) Biochem. Biophys. Res. Commun. , vol.287 , pp. 198
    • Yamanaka, Y.1    Tamari, M.2    Nakahata, T.3    Nakamura, Y.4
  • 45
    • 0031867390 scopus 로고    scopus 로고
    • Erythromycin and clarithromycin attenuate cytokine-induced endothelin-1 expression in human bronchial epithelial cells
    • Takizawa H, Desaki M, Ohtoshi T, Kawasaki S, Kohyama T, Sato M, et al. Erythromycin and clarithromycin attenuate cytokine-induced endothelin-1 expression in human bronchial epithelial cells. Eur Respir J 1998; 12: 57.
    • (1998) Eur. Respir. J. , vol.12 , pp. 57
    • Takizawa, H.1    Desaki, M.2    Ohtoshi, T.3    Kawasaki, S.4    Kohyama, T.5    Sato, M.6
  • 46
    • 0033000830 scopus 로고    scopus 로고
    • The effects of ketolides on bioactive phospholipid-induced injury to human respiratory epithelium in vitro
    • Feldman C, Anderson R, Theron A, Mokgobu I, Cole P J, Wilson R. The effects of ketolides on bioactive phospholipid-induced injury to human respiratory epithelium in vitro. Eur Respir J 1999; 13: 1022.
    • (1999) Eur. Respir. J. , vol.13 , pp. 1022
    • Feldman, C.1    Anderson, R.2    Theron, A.3    Mokgobu, I.4    Cole, P.J.5    Wilson, R.6
  • 47
    • 0028064262 scopus 로고
    • Erythromycin inhibits cholinergic neuro-effector transmission in canine airway smooth muscle
    • Tagaya E, Tamaoki J, Konno K. Erythromycin inhibits cholinergic neuro-effector transmission in canine airway smooth muscle. Res Commun Mol Pathol Pharmacol 1994; 85: 181.
    • (1994) Res. Commun. Mol. Pathol. Pharmacol. , vol.85 , pp. 181
    • Tagaya, E.1    Tamaoki, J.2    Konno, K.3
  • 48
    • 0028912280 scopus 로고
    • Effects of macrolide antibiotics on neurally mediated contraction of human isolated bronchus
    • Tamaoki J, Tagaya E, Sakai A, Konno K. Effects of macrolide antibiotics on neurally mediated contraction of human isolated bronchus. J Allergy Clin Immunol 1995; 95: 853.
    • (1995) J. Allergy Clin. Immunol. , vol.95 , pp. 853
    • Tamaoki, J.1    Tagaya, E.2    Sakai, A.3    Konno, K.4
  • 49
    • 17544375900 scopus 로고    scopus 로고
    • Inhibition of cellular processing of surfactant protein C by drugs affecting intracellular pH gradients
    • Beers MF Inhibition of cellular processing of surfactant protein C by drugs affecting intracellular pH gradients. J Biol Chem 1996; 271: 14361.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14361
    • Beers, M.F.1
  • 51
    • 0033656943 scopus 로고    scopus 로고
    • Effects of EM on the intracellular Ca 2+ response in A549 cells
    • Cho T, Senda K, Suda T, Kanai M, Nakamura H. Effects of EM on the intracellular Ca 2+ response in A549 cells. Jpn J Antibiot 2000; 53 Suppl A: 14.
    • (2000) Jpn. J. Antibiot. , vol.53 , Issue.SUPPL. A , pp. 14
    • Cho, T.1    Senda, K.2    Suda, T.3    Kanai, M.4    Nakamura, H.5
  • 53
    • 0030894524 scopus 로고    scopus 로고
    • Evidence that thrombin-stimulated DNA synthesis in pulmonary arterial fibroblasts involves phosphatidylinositol 3-kinase-dependent p70 ribosomal S6 kinase activation
    • Belham CM, Scott PH, Twomey DP, Gould GW, Wadsworth RM, Plevin R. Evidence that thrombin-stimulated DNA synthesis in pulmonary arterial fibroblasts involves phosphatidylinositol 3-kinase-dependent p70 ribosomal S6 kinase activation. Cell Signal 1997; 9: 109.
    • (1997) Cell Signal , vol.9 , pp. 109
    • Belham, C.M.1    Scott, P.H.2    Twomey, D.P.3    Gould, G.W.4    Wadsworth, R.M.5    Plevin, R.6
  • 54
    • 0032704530 scopus 로고    scopus 로고
    • A macrolide antibiotic, roxithromycin, inhibits the growth of nasal polyp fibroblasts
    • Nonaka M, Pawankar R, Tomiyama S, Yagi T. A macrolide antibiotic, roxithromycin, inhibits the growth of nasal polyp fibroblasts. Am J Rhinol 1999; 13: 267.
    • (1999) Am. J. Rhinol. , vol.13 , pp. 267
    • Nonaka, M.1    Pawankar, R.2    Tomiyama, S.3    Yagi, T.4
  • 55
    • 0033947534 scopus 로고    scopus 로고
    • Macrolide treatment decreased the size of nasal polyps and IL-8 levels in nasal lavage
    • Yamada T, Fujieda S, Mori S, Yamamoto H, Saito H. Macrolide treatment decreased the size of nasal polyps and IL-8 levels in nasal lavage. Am J Rhinol 2000; 14: 143.
    • (2000) Am. J. Rhinol. , vol.14 , pp. 143
    • Yamada, T.1    Fujieda, S.2    Mori, S.3    Yamamoto, H.4    Saito, H.5
  • 56
    • 0032868094 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor effects of 14-membered ring macrolides on mouse B16 melanoma cells
    • Yatsunami J, Fukuno Y, Nagata M, Tominaga M, Aoki S, Tsuruta N, et al. Antiangiogenic and antitumor effects of 14-membered ring macrolides on mouse B16 melanoma cells. Clin Exp Metastasis 1999; 17: 361.
    • (1999) Clin. Exp. Metastasis , vol.17 , pp. 361
    • Yatsunami, J.1    Fukuno, Y.2    Nagata, M.3    Tominaga, M.4    Aoki, S.5    Tsuruta, N.6
  • 57
    • 0032736078 scopus 로고    scopus 로고
    • Roxithromycin and clarithromycin, 14-membered ring macrolides, potentiate the antitumor activity of cytotoxic agents against mouse B16 melanoma cells
    • Yatsunami J, Fukuno Y, Nagata M, Tsuruta N, Aoki S, Tominaga M, et al. Roxithromycin and clarithromycin, 14-membered ring macrolides, potentiate the antitumor activity of cytotoxic agents against mouse B16 melanoma cells. Cancer Lett 1999; 147: 17.
    • (1999) Cancer Lett. , vol.147 , pp. 17
    • Yatsunami, J.1    Fukuno, Y.2    Nagata, M.3    Tsuruta, N.4    Aoki, S.5    Tominaga, M.6
  • 58
    • 0031726243 scopus 로고    scopus 로고
    • Inhibition of tumor angiogenesis by roxithromycin, a 14-membered ring macrolide antibiotic
    • Yatsunami J, Tsuruta N, Hara N, Hayashi S. 1998. Inhibition of tumor angiogenesis by roxithromycin, a 14-membered ring macrolide antibiotic. Cancer Lett 131: 137.
    • (1998) Cancer Lett. , vol.131 , pp. 137
    • Yatsunami, J.1    Tsuruta, N.2    Hara, N.3    Hayashi, S.4
  • 59
    • 0030928936 scopus 로고    scopus 로고
    • Inhibition by erythromycin of human pulmonary artery endothelial cell injury induced by human neutrophils
    • Mitsuyama T, Furuno T, Hidaka K, Tanaka T, Abe M, Hara N. Inhibition by erythromycin of human pulmonary artery endothelial cell injury induced by human neutrophils. Respiration 1997; 64: 206.
    • (1997) Respiration , vol.64 , pp. 206
    • Mitsuyama, T.1    Furuno, T.2    Hidaka, K.3    Tanaka, T.4    Abe, M.5    Hara, N.6
  • 60
    • 0030854383 scopus 로고    scopus 로고
    • Neutrophil-induced endothelial cell damage: Inhibition by a 14-membered ring macrolide through the action of nitric oxide
    • Mitsuyama T, Hidaka K, Furuno T, Hara N. Neutrophil-induced endothelial cell damage: inhibition by a 14-membered ring macrolide through the action of nitric oxide. Int Arch Allergy Immunol 1997; 114: 111.
    • (1997) Int. Arch. Allergy Immunol. , vol.114 , pp. 111
    • Mitsuyama, T.1    Hidaka, K.2    Furuno, T.3    Hara, N.4
  • 61
    • 0031906151 scopus 로고    scopus 로고
    • Release of nitric oxide and expression of constitutive nitric oxide synthase of human endothelial cells: Enhancement by a 14-membered ring macrolide
    • Mitsuyama T, Hidaka K, Furuno T, Hara N. Release of nitric oxide and expression of constitutive nitric oxide synthase of human endothelial cells: enhancement by a 14-membered ring macrolide. Mol Cell Biochem 1998; 181: 157.
    • (1998) Mol. Cell Biochem. , vol.181 , pp. 157
    • Mitsuyama, T.1    Hidaka, K.2    Furuno, T.3    Hara, N.4
  • 64
    • 0031024308 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced goblet cell hypersecretion in the guinea pig trachea: Inhibition by macrolides
    • Tamaoki J, Takeyama K, Yamawaki I, Kondo M, Konno K. Lipopolysaccharide-induced goblet cell hypersecretion in the guinea pig trachea: inhibition by macrolides. Am J Physiol 1997; 272: L15.
    • (1997) Am. J. Physiol. , vol.272
    • Tamaoki, J.1    Takeyama, K.2    Yamawaki, I.3    Kondo, M.4    Konno, K.5
  • 65
    • 0033385193 scopus 로고    scopus 로고
    • Suppressive activity of a macrolide antibiotic, roxithromycin, on pro-inflammatory cytokine production in vitro and in vivo
    • Suzaki H, Asano K, Ohki S, Kanai K, Mizutani T, Hisamitsu T. Suppressive activity of a macrolide antibiotic, roxithromycin, on pro-inflammatory cytokine production in vitro and in vivo. Mediators Inflamm 1999; 8: 199.
    • (1999) Mediators Inflamm. , vol.8 , pp. 199
    • Suzaki, H.1    Asano, K.2    Ohki, S.3    Kanai, K.4    Mizutani, T.5    Hisamitsu, T.6
  • 66
    • 0023710680 scopus 로고
    • Single-dose treatment of neonatal calf pneumonia with the new macrolide antibiotic tilmicosin
    • Ose EE, Tonkinson LV. Single-dose treatment of neonatal calf pneumonia with the new macrolide antibiotic tilmicosin. Vet Rec 1988; 123: 367.
    • (1988) Vet. Rec. , vol.123 , pp. 367
    • Ose, E.E.1    Tonkinson, L.V.2
  • 67
    • 0024409816 scopus 로고
    • Effect of a new macrolide antibiotic (tilmicosin) on pneumonia experimentally induced in calves by Mycoplasma bovis and Pasteurella haemolytica
    • Gourlay RN, Thomas LH, Wyld SG, Smith CJ. Effect of a new macrolide antibiotic (tilmicosin) on pneumonia experimentally induced in calves by Mycoplasma bovis and Pasteurella haemolytica. Res Vet Sci 1989; 47: 84.
    • (1989) Res. Vet. Sci. , vol.47 , pp. 84
    • Gourlay, R.N.1    Thomas, L.H.2    Wyld, S.G.3    Smith, C.J.4
  • 71
    • 0027228155 scopus 로고
    • The comparative activity of azithromycin, macrolides and amoxycillin against streptococci in experimental infections
    • Girard AE, Cimochowski CR, Faiella JA. The comparative activity of azithromycin, macrolides and amoxycillin against streptococci in experimental infections. J Antimicrob Chemother 1993; 31 Suppl E: 29.
    • (1993) J. Antimicrob. Chemother. , vol.31 , Issue.SUPPL. E , pp. 29
    • Girard, A.E.1    Cimochowski, C.R.2    Faiella, J.A.3
  • 73
    • 0029125314 scopus 로고
    • New pathogens and mode of action of azithromycin: Toxoplasma gondii
    • Derouin F. New pathogens and mode of action of azithromycin: Toxoplasma gondii. Pathol Biol (Paris) 1995; 43: 561.
    • (1995) Pathol. Biol. (Paris) , vol.43 , pp. 561
    • Derouin, F.1
  • 74
    • 0029160543 scopus 로고
    • In-vitro and in-vivo activities of roxithromycin in combination with pyrimethamine or sulphadiazine against Toxoplasma gondii
    • Romand S, Bryskier A, Moutot M, Derouin F. In-vitro and in-vivo activities of roxithromycin in combination with pyrimethamine or sulphadiazine against Toxoplasma gondii. J Antimicrob Chemother 1995; 35: 821.
    • (1995) J. Antimicrob. Chemother. , vol.35 , pp. 821
    • Romand, S.1    Bryskier, A.2    Moutot, M.3    Derouin, F.4
  • 75
    • 0031946924 scopus 로고    scopus 로고
    • Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model
    • Brun-Pascaud M, Chau F, Derouin F, Girard PM. Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model. J Antimicrob Chemother 1998; 41 Suppl B: 57.
    • (1998) J. Antimicrob. Chemother. , vol.41 , Issue.SUPPL. B , pp. 57
    • Brun-Pascaud, M.1    Chau, F.2    Derouin, F.3    Girard, P.M.4
  • 76
    • 0032773290 scopus 로고    scopus 로고
    • Preparation, relative toxicity and therapeutic efficacy in mice and rats of liposomal HA-1-92, a new oxohexaene polyene macrolide antibiotic
    • Harindran J, Chakraborty KK, Naik SR. Preparation, relative toxicity and therapeutic efficacy in mice and rats of liposomal HA-1-92, a new oxohexaene polyene macrolide antibiotic. J Pharm Pharmacol 1999; 51: 771.
    • (1999) J. Pharm. Pharmacol. , vol.51 , pp. 771
    • Harindran, J.1    Chakraborty, K.K.2    Naik, S.R.3
  • 77
    • 0035165625 scopus 로고    scopus 로고
    • Kinetic study of the inflammatory response in Streptococcus pneumoniae experimental pneumonia treated with the ketolide HMR 3004
    • Duong M, Simard M, Bergeron Y, Bergeron MG. Kinetic study of the inflammatory response in Streptococcus pneumoniae experimental pneumonia treated with the ketolide HMR 3004. Antimicrob Agents Chemother 2001; 45: 252.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 252
    • Duong, M.1    Simard, M.2    Bergeron, Y.3    Bergeron, M.G.4
  • 78
  • 81
    • 0033771564 scopus 로고    scopus 로고
    • Intrapulmonary concentrations of inflammatory cytokines in a mouse model of chronic respiratory infection caused by Pseudomonas aeruginosa
    • Yanagihara K, Tomono K, Kuroki M, Kaneko Y, Sawai T, Ohno H, Miyazaki Y, et al. Intrapulmonary concentrations of inflammatory cytokines in a mouse model of chronic respiratory infection caused by Pseudomonas aeruginosa. Clin Exp Immunol 2000; 122: 67.
    • (2000) Clin. Exp. Immunol. , vol.122 , pp. 67
    • Yanagihara, K.1    Tomono, K.2    Kuroki, M.3    Kaneko, Y.4    Sawai, T.5    Ohno, H.6    Miyazaki, Y.7
  • 83
    • 0023200899 scopus 로고
    • Erythromycin-induced suppression of pulmonary antibacterial defenses. A potential mechanism of superinfection in the lung
    • Nelson S, Summer WR, Terry PB, Warr GA, Jakab GJ. Erythromycin-induced suppression of pulmonary antibacterial defenses. A potential mechanism of superinfection in the lung. Am Rev Respir Dis 1987; 136(5): 1207-12.
    • (1987) Am. Rev. Respir. Dis. , vol.136 , Issue.5 , pp. 1207-1212
    • Nelson, S.1    Summer, W.R.2    Terry, P.B.3    Warr, G.A.4    Jakab, G.J.5
  • 84
    • 0035996094 scopus 로고    scopus 로고
    • Macrolide-treated Pseudomonas aeruginosa induces paradoxical host responses in the lungs of mice and a high mortality rate
    • Kobayashi T, Tateda K, Matsumoto T, Miyazaki S, Watanabe A, Nukiwa T, et a]. Macrolide-treated Pseudomonas aeruginosa induces paradoxical host responses in the lungs of mice and a high mortality rate. J Antimicrob Chemother 2002; 50: 59.
    • (2002) J. Antimicrob. Chemother. , vol.50 , pp. 59
    • Kobayashi, T.1    Tateda, K.2    Matsumoto, T.3    Miyazaki, S.4    Watanabe, A.5    Nukiwa, T.6
  • 85
    • 0024988207 scopus 로고
    • Inhibitory effect of FK-506 on the development of late asthmatic response and on the increased bronchial responsiveness
    • Akutsu I, Fukuda T, Numao T, Makino S. Inhibitory effect of FK-506 on the development of late asthmatic response and on the increased bronchial responsiveness. Arerugi 1990; 39: 605.
    • (1990) Arerugi , vol.39 , pp. 605
    • Akutsu, I.1    Fukuda, T.2    Numao, T.3    Makino, S.4
  • 86
    • 0027360589 scopus 로고
    • Reduction of Sephadex-induced lung inflammation and bronchial hyperreactivity by rapamycin
    • Francischi JN, Conroy DM, Cloutier S, Sirois P. Reduction of Sephadex-induced lung inflammation and bronchial hyperreactivity by rapamycin. Braz J Med Biol Res 1993; 26: 1105.
    • (1993) Braz. J. Med. Biol. Res. , vol.26 , pp. 1105
    • Francischi, J.N.1    Conroy, D.M.2    Cloutier, S.3    Sirois, P.4
  • 87
    • 0028036936 scopus 로고
    • Antiasthmatic activity of a macrolide antibiotic, roxithromycin: Analysis of possible mechanisms in vitro and in vivo
    • Konno S, Asano K, Kurokawa M, Ikeda K, Okamoto K, Adachi M. Antiasthmatic activity of a macrolide antibiotic, roxithromycin: analysis of possible mechanisms in vitro and in vivo. Int Arch Allergy Immunol 1994; 105: 308.
    • (1994) Int. Arch. Allergy Immunol. , vol.105 , pp. 308
    • Konno, S.1    Asano, K.2    Kurokawa, M.3    Ikeda, K.4    Okamoto, K.5    Adachi, M.6
  • 88
    • 0035051557 scopus 로고    scopus 로고
    • Selective regulation of T cell IL-5 synthesis by OM-01, JTE-711 and p38 MAP kinase inhibitor: Independent control of Th2 cytokines, IL-4 and IL-5
    • Mori A, Okudaira H, Kobayashi N, Akiyama K. Selective regulation of T cell IL-5 synthesis by OM-01, JTE-711 and p38 MAP kinase inhibitor: independent control of Th2 cytokines, IL-4 and IL-5. Int Arch Allergy Immunol 2001; 124: 172.
    • (2001) Int. Arch. Allergy Immunol. , vol.124 , pp. 172
    • Mori, A.1    Okudaira, H.2    Kobayashi, N.3    Akiyama, K.4
  • 90
    • 0031897527 scopus 로고    scopus 로고
    • Preventive effect of erythromycin on experimental bleomycin-induced acute lung injury in rats
    • Azuma A, Furuta T, Enomoto T, Hashimoto Y, Uematsu K, Nukariya N, et al. Preventive effect of erythromycin on experimental bleomycin-induced acute lung injury in rats. Thorax 1998; 53: 186.
    • (1998) Thorax , vol.53 , pp. 186
    • Azuma, A.1    Furuta, T.2    Enomoto, T.3    Hashimoto, Y.4    Uematsu, K.5    Nukariya, N.6
  • 91
    • 0030203457 scopus 로고    scopus 로고
    • Immunomodulation as asthma therapy: Where do we stand?
    • Barnes PJ. Immunomodulation as asthma therapy: where do we stand? Eur Respir J Suppl 1996; 22: 154s.
    • (1996) Eur. Respir. J. Suppl. , vol.22
    • Barnes, P.J.1
  • 92
    • 0036460663 scopus 로고    scopus 로고
    • Inhibitory effects of 14-membered ring macrolide antibiotics on bleomycin-induced acute lung injury
    • Kawashima M, Yatsunami J, Fukuno Y, Nagata M, Tominaga M, Hayashi S. Inhibitory effects of 14-membered ring macrolide antibiotics on bleomycin-induced acute lung injury. Lung 2002; 180: 73.
    • (2002) Lung , vol.180 , pp. 73
    • Kawashima, M.1    Yatsunami, J.2    Fukuno, Y.3    Nagata, M.4    Tominaga, M.5    Hayashi, S.6
  • 93
    • 0036930166 scopus 로고    scopus 로고
    • Fourteen-membered ring macrolides inhibit vascular cell adhesion molecule 1 messenger RNA induction and leukocyte migration: Role in preventing lung injury and fibrosis in bleomycin-challenged mice
    • Li Y, Azuma A, Takahashi S, Usuki J, Matsuda K, Aoyama A, et al. Fourteen-membered ring macrolides inhibit vascular cell adhesion molecule 1 messenger RNA induction and leukocyte migration: role in preventing lung injury and fibrosis in bleomycin-challenged mice. Chest 2002; 122: 2137.
    • (2002) Chest , vol.122 , pp. 2137
    • Li, Y.1    Azuma, A.2    Takahashi, S.3    Usuki, J.4    Matsuda, K.5    Aoyama, A.6
  • 96
    • 0031083746 scopus 로고    scopus 로고
    • Evaluation of antineoplastic effect of CAM (clarithromycin) in a mouse model inoculated with lung cancer cells
    • Hamada K, Sakamoto M, Mikasa K, Teramoto M, Mori K, Tsujimoto M, et al. Evaluation of antineoplastic effect of CAM (clarithromycin) in a mouse model inoculated with lung cancer cells. Jpn J Antibiot 1997; 50 Suppl: 28.
    • (1997) Jpn. J. Antibiot. , vol.50 , Issue.SUPPL. , pp. 28
    • Hamada, K.1    Sakamoto, M.2    Mikasa, K.3    Teramoto, M.4    Mori, K.5    Tsujimoto, M.6
  • 100
    • 0025167374 scopus 로고
    • Morphological rejection phases and cytotoxic activity in peripheral blood lymphocytes in canine lung allo-transplantation
    • Saitoh Y, Fujisawa T, Ogawa T, Urabe N, Yamaguchi Y, Kimizuka G. Morphological rejection phases and cytotoxic activity in peripheral blood lymphocytes in canine lung allo-transplantation. Jpn J Surg 1990; 20: 205.
    • (1990) Jpn. J. Surg. , vol.20 , pp. 205
    • Saitoh, Y.1    Fujisawa, T.2    Ogawa, T.3    Urabe, N.4    Yamaguchi, Y.5    Kimizuka, G.6
  • 101
    • 0026071824 scopus 로고
    • Immunosuppressive effects of FK 506 and 15-deoxyspergualin in rat lung transplantation
    • Katayama Y, Takao M, Onoda K, Hiraiwa T, Yada I, Namikawa S, et al. Immunosuppressive effects of FK 506 and 15-deoxyspergualin in rat lung transplantation. Transplant Proc 1991; 23: 349.
    • (1991) Transplant Proc. , vol.23 , pp. 349
    • Katayama, Y.1    Takao, M.2    Onoda, K.3    Hiraiwa, T.4    Yada, I.5    Namikawa, S.6
  • 102
    • 0027380754 scopus 로고
    • Murine recipients of fully mismatched donor marrow are protected from lethal graft-versus-host disease by the in vivo administration of rapamycin but develop an autoimmune-like syndrome
    • Blazar BR, Taylor PA, Snover DC, Sehgal SN, Vallera DA. Murine recipients of fully mismatched donor marrow are protected from lethal graft-versus-host disease by the in vivo administration of rapamycin but develop an autoimmune-like syndrome. J Immunol 1993; 151: 5726.
    • (1993) J. Immunol. , vol.151 , pp. 5726
    • Blazar, B.R.1    Taylor, P.A.2    Snover, D.C.3    Sehgal, S.N.4    Vallera, D.A.5
  • 103
    • 0034650246 scopus 로고    scopus 로고
    • Combined immunosuppression with cyclosporine (neoral) and SDZ RAD in non-human primate lung transplantation: Systematic pharmacokinetic-based trials to improve efficacy and tolerability
    • Hausen B, Ikonen T, Briffa N, Berry GJ, Christians U, Robbins RC, et al. Combined immunosuppression with cyclosporine (neoral) and SDZ RAD in non-human primate lung transplantation: systematic pharmacokinetic-based trials to improve efficacy and tolerability. Transplantation 2000; 69: 76.
    • (2000) Transplantation , vol.69 , pp. 76
    • Hausen, B.1    Ikonen, T.2    Briffa, N.3    Berry, G.J.4    Christians, U.5    Robbins, R.C.6
  • 105
    • 0032201182 scopus 로고    scopus 로고
    • Effects of long-term preoperative administration of low-dose erythromycin on warm ischemia-reperfusion pulmonary injury
    • Kaji M, Inoue K, Kinoshita H. Effects of long-term preoperative administration of low-dose erythromycin on warm ischemia-reperfusion pulmonary injury. Nihon Kokyuki Gakkai Zasshi 1998; 36: 939.
    • (1998) Nihon Kokyuki Gakkai Zasshi , vol.36 , pp. 939
    • Kaji, M.1    Inoue, K.2    Kinoshita, H.3
  • 106
    • 0025089886 scopus 로고
    • Experimental treatment of autoimmune MRL-1pr/1pr mice with immunosuppressive compound FK506
    • Yamamoto K, Mori A, Nakahama T, Ito M, Okudaira H, Miyamoto T. Experimental treatment of autoimmune MRL-1pr/1pr mice with immunosuppressive compound FK506. Immunology 1990; 69: 222.
    • (1990) Immunology , vol.69 , pp. 222
    • Yamamoto, K.1    Mori, A.2    Nakahama, T.3    Ito, M.4    Okudaira, H.5    Miyamoto, T.6
  • 107
    • 0032969895 scopus 로고    scopus 로고
    • Effects of erythromycin on experimental extrinsic allergic alveolitis
    • Miyajima M, Suga M, Nakagawa K, Ito K, Ando M. Effects of erythromycin on experimental extrinsic allergic alveolitis. Clin Exp Allergy 1999; 29: 253.
    • (1999) Clin. Exp. Allergy , vol.29 , pp. 253
    • Miyajima, M.1    Suga, M.2    Nakagawa, K.3    Ito, K.4    Ando, M.5
  • 108
    • 0033794059 scopus 로고    scopus 로고
    • Interference of antibacterial agents with phagocyte functions: Immunomodulation or "immuno-fairy tales"
    • Labro MT. Interference of antibacterial agents with phagocyte functions: immunomodulation or "immuno-fairy tales". Clin Micro Reviews 2000; 13: 615.
    • (2000) Clin. Micro. Reviews , vol.13 , pp. 615
    • Labro, M.T.1
  • 109
    • 0036367733 scopus 로고    scopus 로고
    • Selective inhibition of osteoclast vacuolar H(+)-ATPase
    • Farina C, Gagliardi S. Selective inhibition of osteoclast vacuolar H(+)-ATPase. Curr Pharm Design 2002; 8(23): 2033-48.
    • (2002) Curr. Pharm. Design , vol.8 , Issue.23 , pp. 2033-2048
    • Farina, C.1    Gagliardi, S.2
  • 110
    • 0036237960 scopus 로고    scopus 로고
    • Cytokine manipulation of the immune response in the treatment of human acute leukaemia
    • Gottlieb D. Cytokine manipulation of the immune response in the treatment of human acute leukaemia. Curr Pharm Design 2002; 8(5): 419-31.
    • (2002) Curr. Pharm. Design , vol.8 , Issue.5 , pp. 419-431
    • Gottlieb, D.1
  • 111
    • 0035993373 scopus 로고    scopus 로고
    • Cytokine modulation for anti-allergic treatment
    • Pullerits T. Cytokine modulation for anti-allergic treatment. Curr Pharm Design 2002; 8(20): 1845-53.
    • (2002) Curr. Pharm. Design , vol.8 , Issue.20 , pp. 1845-1853
    • Pullerits, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.