Macrolide-treated Pseudomonas aeruginosa induces paradoxical host responses in the lungs of mice and a high mortality rate

Journal of Antimicrobial Chemotherapy

Volumn 50, Issue 1, 2002, Pages 59-66

  Kobayashi, Takao ^a,b   Tateda, Kazuhiro ^a   Matsumoto, Tetsuya ^a   Miyazaki, Shuichi ^a   Watanabe, Akira ^b   Nukiwa, Toshihiro ^b   Yamaguchi, Keizo ^a  

^a TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CEFTAZIDIME; CLARITHROMYCIN; CLINDAMYCIN; ERYTHROMYCIN; JOSAMYCIN; MACROLIDE; MINOCYCLINE; NITRIC OXIDE; OFLOXACIN; OLEANDOMYCIN; PROTEIN; TOBRAMYCIN; TUMOR NECROSIS FACTOR ALPHA; ANTIINFECTIVE AGENT; PANCREATIC ELASTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG EFFICACY; IMMUNE RESPONSE; IN VIVO STUDY; INOCULATION; LUNG LAVAGE; LUNG WEIGHT; MALE; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; MOUSE; NONHUMAN; NOSE; PERMEABILITY; PROVOCATION TEST; PSEUDOMONAS AERUGINOSA; ANIMAL; BACTERIAL PNEUMONIA; BIOSYNTHESIS; CHEMISTRY; DISEASE MODEL; DRUG EFFECT; GRAM NEGATIVE INFECTION; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; LUNG; METABOLISM; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; VIRULENCE;

ANIMALS; ANTI-BACTERIAL AGENTS; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; LUNG; MACROLIDES; MALE; MICE; MICE, INBRED ICR; MICROBIAL SENSITIVITY TESTS; NITRIC OXIDE; PANCREATIC ELASTASE; PNEUMONIA, BACTERIAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; TUMOR NECROSIS FACTOR-ALPHA; VIRULENCE;

EID: 0035996094     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkf048     Document Type: Article

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