메뉴 건너뛰기




Volumn 63, Issue 19, 2003, Pages 6149-6153

Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DOXORUBICIN; ETOPOSIDE; G QUADRUPLEX LIGAND 12459; MITOMYCIN C; TELOMERASE; TELOMERASE INHIBITOR; TELOMESTATIN; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; VINBLASTINE;

EID: 0141988720     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (60)

References (22)
  • 1
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • Blackburn, E. H. Switching and signaling at the telomere. Cell, 106: 661-673, 2001.
    • (2001) Cell , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 3
    • 0037142071 scopus 로고    scopus 로고
    • Crystal structure of parallel quadruplexes from human telomeric DNA
    • Parkinson, G. N., Lee, M. P., and Neidle, S. Crystal structure of parallel quadruplexes from human telomeric DNA. Nature (Lond.), 417: 876-880, 2002.
    • (2002) Nature (Lond.) , vol.417 , pp. 876-880
    • Parkinson, G.N.1    Lee, M.P.2    Neidle, S.3
  • 4
    • 0035902465 scopus 로고    scopus 로고
    • In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei
    • Schaffitzel, C., Berger, I., Postberg, J., Hanes, J., Lipps, H. J., and Pluckthun, A. In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei. Proc. Natl. Acad. Sci. USA, 98: 8572-8577, 2001.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 8572-8577
    • Schaffitzel, C.1    Berger, I.2    Postberg, J.3    Hanes, J.4    Lipps, H.J.5    Pluckthun, A.6
  • 5
    • 0037015078 scopus 로고    scopus 로고
    • Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
    • Siddiqui-Jain, A., Grand, C. L., Bearss, D. J., and Hurley, L. H. Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription. Proc. Natl. Acad. Sci. USA, 99: 11593-11598, 2002.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 11593-11598
    • Siddiqui-Jain, A.1    Grand, C.L.2    Bearss, D.J.3    Hurley, L.H.4
  • 6
    • 0036699095 scopus 로고    scopus 로고
    • Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA
    • Cheung, I., Schertzer, M., Rose, A., and Lansdorp, P. M. Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA. Nat. Genet., 31: 405-409, 2002.
    • (2002) Nat. Genet. , vol.31 , pp. 405-409
    • Cheung, I.1    Schertzer, M.2    Rose, A.3    Lansdorp, P.M.4
  • 9
    • 0036562687 scopus 로고    scopus 로고
    • Telomere maintenance as a target for anticancer drug discovery
    • Neidle, S., and Parkinson, G. Telomere maintenance as a target for anticancer drug discovery. Nat. Rev. Drug Discov., 1: 383-393, 2002.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 383-393
    • Neidle, S.1    Parkinson, G.2
  • 12
    • 0037096736 scopus 로고    scopus 로고
    • Detection of telomerase inhibitors based on g-quadruplex ligands by a modified telomeric repeat amplification protocol assay
    • Gomez, D., Mergny, J. L., and Riou, J. F. Detection of telomerase inhibitors based on g-quadruplex ligands by a modified telomeric repeat amplification protocol assay. Cancer Res., 62: 3365-3368, 2002.
    • (2002) Cancer Res. , vol.62 , pp. 3365-3368
    • Gomez, D.1    Mergny, J.L.2    Riou, J.F.3
  • 13
    • 0037070575 scopus 로고    scopus 로고
    • Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex
    • Kim, M. Y., Vankayalapati, H., Shin-Ya, K., Wierzba, K., and Hurley, L. H. Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex. J. Am. Chem. Soc., 124: 2098-2099, 2002.
    • (2002) J. Am. Chem. Soc. , vol.124 , pp. 2098-2099
    • Kim, M.Y.1    Vankayalapati, H.2    Shin-Ya, K.3    Wierzba, K.4    Hurley, L.H.5
  • 14
    • 1842414238 scopus 로고    scopus 로고
    • Molecular basis of artifacts in the detection of telomerase activity and a modified primer for a more robust 'TRAP' assay
    • Krupp, G., Kuhne, K., Tamm, S., Klapper, W., Heidorn, K., Rott, A., and Parwaresch, R. Molecular basis of artifacts in the detection of telomerase activity and a modified primer for a more robust 'TRAP' assay. Nucleic Acids Res., 25: 919-921, 1997.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 919-921
    • Krupp, G.1    Kuhne, K.2    Tamm, S.3    Klapper, W.4    Heidorn, K.5    Rott, A.6    Parwaresch, R.7
  • 15
    • 0035584117 scopus 로고    scopus 로고
    • Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells
    • Yi, X., Shay, J. W., and Wright, W. E. Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells. Nucleic Acids Res., 29: 4818-4825, 2001.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 4818-4825
    • Yi, X.1    Shay, J.W.2    Wright, W.E.3
  • 16
    • 0031000884 scopus 로고    scopus 로고
    • Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
    • Makarov, V. L., Hirose, Y., and Langmore, J. P. Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell, 88: 657-666, 1997.
    • (1997) Cell , vol.88 , pp. 657-666
    • Makarov, V.L.1    Hirose, Y.2    Langmore, J.P.3
  • 18
    • 0033577876 scopus 로고    scopus 로고
    • Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT)
    • Wick, M., Zubov, D., and Hagen, G. Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT). Gene, 232: 97-106, 1999.
    • (1999) Gene , vol.232 , pp. 97-106
    • Wick, M.1    Zubov, D.2    Hagen, G.3
  • 20
    • 0035900649 scopus 로고    scopus 로고
    • Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function
    • Darnell, J. C., Jensen, K. B., Jin, P., Brown, V., Warren, S. T., and Darnell, R. B. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell, 107: 489-499, 2001.
    • (2001) Cell , vol.107 , pp. 489-499
    • Darnell, J.C.1    Jensen, K.B.2    Jin, P.3    Brown, V.4    Warren, S.T.5    Darnell, R.B.6
  • 22
    • 0037148270 scopus 로고    scopus 로고
    • New ways not to make ends meet: Telomerase. DNA damage proteins and heterochromatin
    • Chan, S. W., and Blackburn, E. H. New ways not to make ends meet: telomerase. DNA damage proteins and heterochromatin. Oncogene, 21: 553-563, 2002.
    • (2002) Oncogene , vol.21 , pp. 553-563
    • Chan, S.W.1    Blackburn, E.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.