Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction

Current Biology

Volumn 14, Issue 18, 2004, Pages 1657-1663

  Israely, Inbal ^a   Costa, Rui M ^a,b   Xie, Cui Wei ^b   Silva, Alcino J ^a,b   Kosik, Kenneth S ^c   Liu, Xin ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARMADILLO DOMAIN PROTEIN; CADHERIN; CADHERIN ASSOCIATED SRC SUBSTRATE P120; CADHERIN-ASSOCIATED SRC SUBSTRATE P120; CELL ADHESION MOLECULE; CYTOSKELETON PROTEIN; DLGH4 PROTEIN, MOUSE; MEMBRANE PROTEIN; NERVE PROTEIN; PHOSPHOPROTEIN; POSTSYNAPTIC DENSITY PROTEINS; SIGNAL PEPTIDE;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; COGNITIVE DEFECT; COMPARATIVE STUDY; CONDITIONING; DEGENERATIVE DISEASE; ELECTROPHYSIOLOGY; FEAR; GENETICS; HIPPOCAMPUS; IMMUNOPRECIPITATION; MAZE TEST; METABOLISM; MOUSE; MOUSE MUTANT; MUTATION; NERVE CELL; NERVE CELL PLASTICITY; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; SYNAPSE;

ANALYSIS OF VARIANCE; ANIMALS; ARMADILLO DOMAIN PROTEINS; CADHERINS; CELL ADHESION MOLECULES; COGNITION DISORDERS; CONDITIONING (PSYCHOLOGY); CYTOSKELETAL PROTEINS; ELECTROPHYSIOLOGY; FEAR; HIPPOCAMPUS; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAZE LEARNING; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; MUTATION; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; NEURONAL PLASTICITY; NEURONS; PHOSPHOPROTEINS; PSYCHOMOTOR PERFORMANCE; SYNAPSES;

ANIMALIA; FELIS CATUS;

EID: 4544246530     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2004.08.065     Document Type: Article

References (27)

1. Kim K., Sirota A., Chen Yh Y.H., Jones S.B., Dudek R., Lanford G.W., Thakore C., Lu Q. Dendrite-like process formation and cytoskeletal remodeling regulated by delta-catenin expression. Exp. Cell Res. 275:2002;171-184
2. Martinez M.C., Ochiishi T., Majewski M., Kosik K.S. Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho. J. Cell Biol. 162:2003;99-111
3. Medina M., Marinescu R.C., Overhauser J., Kosik K.S. Hemizygosity of delta-catenin (CTNND2) is associated with severe mental retardation in cri-du-chat syndrome. Genomics. 63:2000;157-164
4. Zhou J., Liyanage U., Medina M., Ho C., Simmons A.D., Lovett M., Kosik K.S. Presenilin 1 interaction in the brain with a novel member of the Armadillo family. Neuroreport. 8:1997;2085-2090
5. Lu Q., Paredes M., Medina M., Zhou J., Cavallo R., Peifer M., Orecchio L., Kosik K.S. delta-catenin, an adhesive junction-associated protein which promotes cell scattering. J. Cell Biol. 144:1999;519-532
6. Cho Y.H., Friedman E., Silva A.J. Ibotenate lesions of the hippocampus impair spatial learning but not contextual fear conditioning in mice. Behav. Brain Res. 98:1999;77-87
7. Brandeis R., Brandys Y., Yehuda S. The use of the Morris Water Maze in the study of memory and learning. Int. J. Neurosci. 48:1989;29-69
8. Schenk F., Morris R.G. Dissociation between components of spatial memory in rats after recovery from the effects of retrohippocampal lesions. Exp. Brain Res. 58:1985;11-28
9. Maren S. Neurobiology of Pavlovian fear conditioning. Annu. Rev. Neurosci. 24:2001;897-931
10. Anagnostaras S.G., Josselyn S.A., Frankland P.W., Silva A.J. Computer-assisted behavioral assessment of Pavlovian fear conditioning in mice. Learn. Mem. 7:2000;58-72
11. Matynia A., Kushner S.A., Silva A.J. Genetic approaches to molecular and cellular cognition. a focus on LTP and learning and memory Annu. Rev. Genet. 36:2002;687-720
12. Rogan M.T., Staubli U.V., LeDoux J.E. Fear conditioning induces associative long-term potentiation in the amygdala. Nature. 390:1997;604-607
13. Beurrier C., Malenka R.C. Enhanced inhibition of synaptic transmission by dopamine in the nucleus accumbens during behavioral sensitization to cocaine. J. Neurosci. 22:2002;5817-5822
14. Thompson R.F. Cerebral substrates of Pavlovian conditioning of discrete behavioral responses. Neurosci. Behav. Physiol. 27:1997;635-637
15. Otto T., Eichenbaum H., Wiener S.I., Wible C.G. Learning-related patterns of CA1 spike trains parallel stimulation parameters optimal for inducing hippocampal long-term potentiation. Hippocampus. 1:1991;181-192
16. Tang L., Hung C.P., Schuman E.M. A role for the cadherin family of cell adhesion molecules in hippocampal long-term potentiation. Neuron. 20:1998;1165-1175
17. Tanaka H., Shan W., Phillips G.R., Arndt K., Bozdagi O., Shapiro L., Huntley G.W., Benson D.L., Colman D.R. Molecular modification of N-cadherin in response to synaptic activity. Neuron. 25:2000;93-107
18. Murase S., Mosser E., Schuman E.M. Depolarization drives beta-Catenin into neuronal spines promoting changes in synaptic structure and function. Neuron. 35:2002;91-105
19. Davis M.A., Ireton R.C., Reynolds A.B. A core function for p120-catenin in cadherin turnover. J. Cell Biol. 163:2003;525-534
20. Jones S.B., Lanford G.W., Chen Y.H., Moribito M., Kim K., Lu Q. Glutamate-induced delta-catenin redistribution and dissociation from postsynaptic receptor complexes. Neuroscience. 115:2002;1009-1021
21. Garner C.C., Nash J., Huganir R.L. PDZ domains in synapse assembly and signalling. Trends Cell Biol. 10:2000;274-280
22. Sheng M., Sala C. PDZ domains and the organization of supramolecular complexes. Annu. Rev. Neurosci. 24:2001;1-29
23. Liauw J., Nguyen V., Huang J., St George-Hyslop P., Rozmahel R. Differential display analysis of presenilin 1-deficient mouse brains. Brain Res. Mol. Brain Res. 109:2002;56-62
24. Migaud M., Charlesworth P., Dempster M., Webster L.C., Watabe A.M., Makhinson M., He Y., Ramsay M.F., Morris R.G., Morrison J.H., O'Dell T.J., Grant S.G. Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein. Nature. 396:1998;433-439
25. Bourtchuladze R., Frenguelli B., Blendy J., Cioffi D., Schutz G., Silva A.J. Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell. 79:1994;59-68
26. Silva A.J., Frankland P.W., Marowitz Z., Friedman E., Laszlo G.S., Cioffi D., Jacks T., Bourtchuladze R., Lazlo G. A mouse model for the learning and memory deficits associated with neurofibromatosis type I. Nat. Genet. 15:1997;281-284
27. Xie C.W., Sayah D., Chen Q.S., Wei W.Z., Smith D., Liu X. Deficient long-term memory and long-lasting long-term potentiation in mice with a targeted deletion of neurotrophin-4 gene. Proc. Natl. Acad. Sci. USA. 97:2000;8116-8121