The role of the immune system in the pathogenesis of prion diseases;Rola UKładu odpornos̈ciowego w patogenezie chorób prionowych

Postepy Higieny i Medycyny Doswiadczalnej

Volumn 62, Issue , 2008, Pages 166-173

  Wierzbicka, Anna ^a   Deptuła, Wiesław ^a  

^a UNIVERSITY OF SZCZECIN   (Poland)

Author keywords

Immune system; Prions

Indexed keywords

ANIMAL; HUMAN; IMMUNE SYSTEM; IMMUNOLOGY; METABOLISM; PATHOPHYSIOLOGY; PRION; PRION DISEASE; REVIEW;

ANIMALS; HUMANS; IMMUNE SYSTEM; PRION DISEASES; PRIONS;

EID: 45349090708     PISSN: 00325449     EISSN: 17322693     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Aguzzi A., Heikenwalder M: Prions, cytokines, and chemokines: A meeting in lymphoid organs. Immunity, 2005; 22: 145-154
2. Aguzzi A., Heikenwalder M., Miele G.: Progress and problems in the biology, diagnostics, and therapeutics of prion diseases. J. Clin. Invest., 2004; 114: 153-160
3. Aguzzi A., Sigurdson C.J.: Antiprion immunotherapy: to suppress or to stimulate? Nat. Rev. Immunol., 2004; 4: 725-736
4. Aucouturier P., Geissmann F., Damotte D., Saborio G.P., Meeker H.C., Kascsak R., Kascsak R., Carp R.I., Wisniewski T.: Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie. J. Clin. Invest., 2001; 108: 703-708
5. Beringue V., Couvreur P., Dormont D.: Involvement of macrophages in the pathogenesis of transmissible spongiform encephalopathies. Dev. Immunol., 2002; 9: 19-27
6. Beringue V., Demoy M., Lasmézas C.I., Gouritin B., Weingarten C., Deslys J.P., Andreux J.P., Couvreur P., Dormont D.: Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis. J. Pathol., 2000; 190: 495-502
7. Blättler T.: Transmission of prion disease. APMIS, 2002; 110: 71-78
8. Campbell I.L., Eddleston M., Kemper P., Oldstone M.B., Hobbs M.V.: Activation of cerebral cytokine gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie. J. Virol., 1994; 68: 2383-2387
9. Cronier S., Laude H., Peyrin J.M.: Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death. Proc. Natl. Acad. Sci. USA, 2004; 101: 12271-12276
10. Daude N.: Prion diseases and the spleen. Viral Immunol., 2004; 17: 334-349
11. Denys A.: Niekonwencjonalne czynniki infekcyjne-priony. Lek. Wojsk., 2002; 78: 268-272
12. Deptuła W., Pawlikowska M.: Charakterystyka chorób prionowych-wybrane dane. Medycyna Wet., 2000; 56: 11-14
13. Deptuła W., Pawlikowska M.: Priony i ich znaczenie u zwierząt i ludzi. Medycyna Wet., 1999; 55: 711-717
14. Deptuła W., Tokarz-Deptuła B., Stosik M.: Immunologia dla biologów. Wydanie nowe. Wydawnictwo Naukowe US, Szczecin 2008
15. Diomede L., Sozzani S., Luini W., Algeri M., De Gioia L., Chiesa R., Lievens P.M., Bugiani O., Forloni G., Tagliavini F., Salmona M.: Activation effects of a prion protein fragment [PrP-(106-126)] on human leukocytes. Biochem. J., 1996; 320: 563-570
16. Gadomska A.: Priony i choroby prionowe. Laboratorium-Przegląd Ogólnopolski, 2004; 5: 48-50
17. Glatzel M., Klein M.A., Brandner S., Aguzzi A.: Prions: from neurografts to neuroinvasion. Arch. Virol. Suppl., 2000; 16: 3-12
18. Gołąb J., Jakóbisiak M.: Immunologia. Red.: Gołąb J., Jakóbisiak M., Lasek W., Wydawnictwo Naukowe PWN, Warszawa 2004, 169-171
19. Heikenwalder M., Zeller N., Seeger H., Prinz M., Klöhn P.C., Schwarz P., Ruddle N.H., Weissmann C., Aguzzi A.: Chronic lymphocytic inflammation specifies the organ tropism of prions. Science, 2005; 307: 1107-1110
20. Herrmann L.M., Baszler T.V., Knowles D.P., Cheevers W.P.: PrPSc is not detected in peripheral blood leukocytes of scrapie-infected sheep: determining the limit of sensitivity by immunohistochemistry. Clin. Diagn. Lab. Immunol., 2002; 9: 499-502
21. Hetz C., Russelakis-Carneiro M., Maundrell K., Castilla J., Soto C.: Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. EMBO J., 2003; 22: 5435-5445
22. Kaneider N.C., Kaser A., Dunzendorfer S., Tilg H., Wiedermann C.J.: Sphingosine kinase-dependent migration of immature dendritic cells in response to neurotoxic prion protein fragment. J. Virol., 2003; 77: 5535-5539
23. Larska M., Polak M.P.: Rola krwi w transmisji chorób prionowych. Med. Weter., 2003; 59: 670-672
24. Lewicki H., Tishon A., Homann D., Mazarguil H., Laval F., Asensio V.C., Campbell I.L., DeArmond S., Coon B., Teng C., Gairin J.E., Oldstone M.B.: T cells infiltrate the brain in murine and human transmissible spongiform encephalopathies. J. Virol., 2003; 77: 3799-3808
25. Luhr K.M., Nordström E.K., Löw P., Ljunggren H.G., Taraboulos A., Kristensson K.: Scrapie protein degradation by cysteine proteases in CD11c+ dendritic cells and GT1-1 neuronal cells. J. Virol., 2004; 78: 4776-4782
26. Luhr K.M., Wallin R.P., Ljunggren H.G., Löw P., Taraboulos A., Kristensson K.: Processing and degradation of exogenous prion protein by CD11c+ myeloid dendritic cells in vitro. J. Virol., 2002; 76: 12259-12264
27. Mabbott N.A.: The complement system in prion diseases. Curr. Opin. Immunol., 2004; 16: 587-593
28. Mabbott N.A., Bruce M.E.: Follicular dendritic cells as targets for intervention in transmissible spongiform encephalopathies. Semin. Immunol., 2002; 14: 285-293
29. Mabbott N.A., Bruce M.E.: The immunobiology of TSE diseases. J. Gen. Virol., 2001; 82: 2307-2318
30. Mabbott N.A., Williams A., Farquhar C.F., Pasparakis M., Kollias G., Bruce M.E.: Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie. J. Virol., 2000; 74: 3338-3344
31. Mabbott N.A., Young J., McConnell I., Bruce M.E.: Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility. J. Virol., 2003; 77: 6845-6854
32. Malinowska A.: Współczesne poglądy na mechanizm rozwoju chorób prionowych. Zycie Wet., 2002; 77: 406-441
33. Marella M., Chabry J.: Neurons and astrocytes respond to prion infection by inducing microglia recruitment. J. Neurosci., 2004; 24: 620-627
34. Miragliotta G., Fumarulo R., Fumarola D.: Inhibition of neutrophil functions by scrapie prion protein: description of some inhibitory properties. Acta Virol., 1990; 34: 517-522
35. Mohan J., Bruce M.E., Mabbott N.A.: Neuroinvasion by scrapie following inoculation via the skin is independent of migratory Langerhans cells. J. Virol., 2005; 79: 1888-1897
36. Montrasio F., Cozzio A., Flechsig E., Rossi D., Klein M.A., Rülicke T., Raeber A.J., Vosshenrich C.A., Proft J., Aguzzi A., Weissmann C.: B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice. Proc. Natl. Acad. Sci. USA, 2001; 98: 4034-4037
37. Prinz M., Heikenwalder M., Junt T., Schwarz P., Glatzel M., Heppner F.L., Fu Y.X., Lipp M., Aguzzi A.: Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion. Nature, 2003; 425: 957-962
38. Prinz M., Montrasio F., Klein M.A., Schwarz P., Priller J., Odermatt B., Pfeffer K., Aguzzi A.: Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells. Proc. Natl. Acad. Sci. USA, 2002; 99: 919-924
39. Prusiner S.B.: Na tropie choroby szalonych krów. ͆wiat Nauki, 2004; 8: 58-66
40. Prusiner S.B.: Novel proteinaceous infectious particles cause scrapie. Science, 1982; 216: 136-144
41. Riesner D.: Molecular basis of prion diseases. J. Neurovirol., 2002; 8 (Suppl.2): 8-20
42. Rock R.B., Gekker G., Hu S., Sheng W.S., Cheeran M., Lokensgard J.R., Peterson P.K.: Role of microglia in central nervous system infections. Clin. Microbiol. Rev., 2004; 17: 942-964
43. Schultz J., Schwarz A., Neidhold S., Burwinkel M., Riemer C., Simon D., Kopf M., Otto M., Baier M.: Role of interleukin-1 in prion diseaseassociated astrocyte activation. Am. J. Pathol., 2004; 165: 671-678
44. Siwicki A.K., Deptuła W.: Priony a układ immunologiczny. W: Immunologia Weterynaryjna. Wybrane zagadnienia. Red. A.K. Siwicki, W. Deptuła, Wydawnictwo Uniwersytet Warmińsko-Mazurski, Olsztyn 2001; 7-9
45. Stone L.A., Jackson G.S., Collinge J., Wadsworth J.D., Clarke A.R.: Inhibition of proteinase K activity by copper(II) ions. Biochemistry, 2007; 46: 245-252
46. Telling G.C.: Prion diseases of humans and animals. In: Viral Ecology. Ed: Hurst C.J. Academic Press 2000, 593-619
47. Thackray A.M., McKenzie A.N., Klein M.A., Lauder A., Bujdoso R.: Accelerated prion disease in the absence of interleukin-10. J. Virol., 2004; 78: 13697-13707