The hominoid-specific oncogene TBC1d3 activates ras and modulates epidermal growth factor receptor signaling and trafficking

Journal of Biological Chemistry

Volumn 283, Issue 19, 2008, Pages 13233-13242

  Wainszelbaum, Marisa J ^a   Charron, Audra J ^a   Kong, Chen ^a   Kirkpatrick, Donald S ^b,c   Srikanth, Priya ^a   Barbieri, M Alejandro ^a,d   Gygi, Steven P ^b   Stahl, Philip D ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c GENENTECH INC   (United States)

^d FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; CELL CULTURE; CELL PROLIFERATION; DEGRADATION; GENES; GROWTH (MATERIALS); NUCLEIC ACIDS; PEPTIDES; RNA; SIGNAL TRANSDUCTION;

ADAPTER PROTEINS; EGF RECEPTORS; EGFR DEGRADATIONS; EPIDERMAL GROWTH FACTOR RECEPTORS; EPIDERMAL GROWTH FACTORS; GENOMICS; GROWTH FACTORS; HIGHER ORDERS; HUMAN TISSUES; LIFE SPANS; LIGHT MICROSCOPIES; MOUSE CELL LINES; PARALOGS; POLYUBIQUITINATION; PROTEIN KINASES; QUIESCENT CELLS; RAS BINDING DOMAINS; RECEPTOR TRAFFICKING; RNA INTERFERENCES; SIGNALING PATHWAYS; UBIQUITINATION; WESTERN BLOTS;

CELL GROWTH;

DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; GUANOSINE TRIPHOSPHATE; IODINE 125; PUROMYCIN; RAS PROTEIN; SMALL INTERFERING RNA; THYMIDINE; TRITIUM; CBL PROTEIN; EPIDERMAL GROWTH FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ONCOPROTEIN; PROTEIN KINASE B; TBC1D3 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CHROMOSOME 17; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST CULTURE; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MICROSCOPY; MOUSE; NONHUMAN; ONCOGENE; ONCOGENE TBC1D3; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DOMAIN; RETROVIRUS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; VIRUS RECOMBINANT; WESTERN BLOTTING; CELL LINE; CELL MEMBRANE; DRUG EFFECT; ENZYME SPECIFICITY; GENETICS; METABOLISM; PROTEIN BINDING; UBIQUITINATION;

HOMINOIDEA; HOMO;

CELL LINE; CELL MEMBRANE; CELL PROLIFERATION; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; GTPASE-ACTIVATING PROTEINS; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; ONCOGENE PROTEINS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-CBL; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SUBSTRATE SPECIFICITY; UBIQUITINATION;

EID: 45149120246     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800234200     Document Type: Article

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