Differential impact of TGF-β and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion

Cancer Letters

Volumn 266, Issue 2, 2008, Pages 263-274

  Denys, Hannelore ^a   Derycke, Lara ^a   Hendrix, An ^a   Westbroek, Wendy ^b   Gheldof, Alexander ^a   Narine, Kishan ^a   Pauwels, Patrick ^a   Gespach, Christian ^c,d   Bracke, Marc ^a   De Wever, Olivier ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c INSERM   (France)

^d SORBONNE UNIVERSITÉ   (France)

Author keywords

bFGF; Heterotypic co cultures; Rho GTPases; Spheroid; Stress fibers; Tenascin C

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; EPIDERMAL GROWTH FACTOR; MATRIGEL; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SEPRASE; TENASCIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CANCER CELL; CANCER MODEL; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL INVASION; COCULTURE; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; MUSCLE FIBER CONTRACTION; MYOFIBROBLAST; POLARIZATION; PRIORITY JOURNAL; STRESS FIBER; STROMA CELL;

ACTINS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MOVEMENT; CELLS, CULTURED; COCULTURE TECHNIQUES; COLLAGEN TYPE I; COLONIC NEOPLASMS; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FIBROBLASTS; HUMANS; MICROFILAMENTS; NEOPLASM INVASIVENESS; RHO GTP-BINDING PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 45049088723     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.02.068     Document Type: Article

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