Antitumour and antiangiogenic effects of Aplidin® in the 5TMM syngeneic models of multiple myeloma

British Journal of Cancer

Volumn 98, Issue 12, 2008, Pages 1966-1974

  Caers, J ^a   Menu, E ^a   De Raeve, H ^b   Lepage, D ^c   Van Valckenborgh, E ^a   Van Camp, B ^a   Alvarez, E ^c   Vanderkerken, K ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UZ ^*  (Belgium)

^c PharmaMar USA Inc   (United States)

Author keywords

Aplidin; Multiple myeloma; Murine models

Indexed keywords

CASPASE 3; CASPASE 9; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYTOCHROME C; DEHYDRODIDEMNIN B; PARAPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE MODEL; DNA SYNTHESIS; DRUG EFFECT; DRUG EFFICACY; DRUG TOLERABILITY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME RELEASE; IC 50; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; MULTIPLE MYELOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL CYCLE; DEPSIPEPTIDES; DISEASE MODELS, ANIMAL; DNA REPLICATION; MICE; MICE, INBRED C57BL; MULTIPLE MYELOMA; RATS;

EID: 44949219133     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604388     Document Type: Article

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