Characterization of metal ligand mutants of phenylalanine hydroxylase: Insights into the plasticity of a 2-histidine-1-carboxylate triad

Archives of Biochemistry and Biophysics

Volumn 475, Issue 2, 2008, Pages 164-168

  Li, Jun ^a   Fitzpatrick, Paul F ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Enzyme kinetics; Iron; Mutagenesis; Phenylalanine hydroxylase

Indexed keywords

6 METHYLTETRAHYDROPTERIN; CARBOXYLIC ACID; GLUTAMIC ACID; GLUTAMINE; HISTIDINE; IRON; LIGAND; METAL; MUTANT PROTEIN; PHENYLALANINE 4 MONOOXYGENASE; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; ENZYME ACTIVITY; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; RAT; WILD TYPE;

ANIMALS; BINDING SITES; CARBOXYLIC ACIDS; ESCHERICHIA COLI; HISTIDINE; IRON; KINETICS; LIGANDS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHENYLALANINE HYDROXYLASE; PROTEIN BINDING; RATS;

RATTUS;

EID: 44949192686     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2008.04.029     Document Type: Article

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