Characterization of metal ligand mutants of tyrosine hydroxylase: Insights into the plasticity of a 2-histidine-1-carboxylate triad

Biochemistry

Volumn 42, Issue 7, 2003, Pages 2081-2088

  Fitzpatrick, Paul F ^a   Ralph, Erik C ^a   Ellis, Holly R ^a,b   Willmon, Opal J ^a   Colette Daubner, S ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b AUBURN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; CHARGE TRANSFER; OXIDATION;

METAL LIGANDS; MUTANTS;

ENZYMES;

2 HISTIDINE 1 CARBOXYLATE; AMINO ACID; CARBOXYLIC ACID; DOPAMINE; GLUTAMIC ACID; GLUTAMINE; IRON; LIGAND; METAL; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME MECHANISM; HYDROXYLATION; ION TRANSPORT; METAL BINDING; MOLECULAR STABILITY; OXIDATION; PLASTICITY; PRIORITY JOURNAL;

AMINO ACID MOTIFS; ANIMALS; BINDING SITES; CARBOXYLIC ACIDS; CATALYSIS; DOPAMINE; GLUTAMIC ACID; GLUTAMINE; HISTIDINE; IRON; KINETICS; LIGANDS; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; RATS; TYROSINE 3-MONOOXYGENASE;

EID: 0037465514     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0271493     Document Type: Article

References (46)

1. Fitzpatrick, P. F. (1999) Annu. Rev. Biochem. 68, 355-381.
2. Hufton, S. E., Jennings, I. G., and Cotton, R. G. H. (1995) Biochem. J. 311, 353-366.
3. Gottschall, D. W., Dietrich, R. F., and Benkovic, S. J. (1982) J. Biol. Chem. 257, 845-849.
4. Fitzpatrick, P. F. (1989) Biochem. Biophys. Res. Commun. 161, 211-215.
5. Moran, G. R., Daubner, S. C., and Fitzpatrick, P. F. (1998) J. Biol. Chem. 273, 12259-12266.
6. Balasubramanian, S., Carr, R. T., Bender, C. J., Peisach, J., and Benkovic, S. J. (1994) Biochemistry 33, 8532-8537.
7. Ramsey, A. J., Daubner, S. C., Ehrlich, J. I., and Fitzpatrick, P. F. (1995) Protein Sci. 4, 2082-2086.
8. Goodwill, K. E., Sabatier, C., Marks, C., Raag, R., Fitzpatrick, P. F., and Stevens, R. C. (1997) Nat. Struct. Biol. 4, 578-585.
9. Erlandsen, H., Fusetti, F., Martinez, A., Hough, E., Flatmark, T., and Stevens, R. C. (1997) Nat. Struct. Biol. 4, 995-1000.
10. Que, L., Jr. (2000) Nat. Struct. Biol. 7, 182-184.
11. Daubner, S. C., Hillas, P. J., and Fitzpatrick, P. F. (1997) Biochemistry 36, 11574-11582.
12. Daubner, S. C., and Fitzpatrick, P. F. (1998) Biochemistry 37, 16440-16444.
13. Ellis, H. R., Daubner, S. C., and Fitzpatrick, P. F. (2000) Biochemistry 39, 4174-4181.
14. Ramsey, A. J., Hillas, P. J., and Fitzpatrick, P. F. (1996) J. Biol. Chem. 271, 24395-24400.
15. Daubner, S. C., Lauriano, C., Haycock, J. W., and Fitzpatrick, P. F. (1992) J. Biol. Chem. 267, 12639-12646.
16. Hillas, P. J., and Fitzpatrick, P. F. (1996) Biochemistry, 35, 6969-6975.
17. Fitzpatrick, P. F. (1991) Biochemistry 30, 3658-3662.
18. Daubner, S. C., and Fitzpatrick, P. F. (1999) Biochemistry 38, 4448-4454.
19. Andersson, K. K., Cox, D. D., Que, L., Jr., Flatmark, T., and Haavik, J. (1988) J. Biol. Chem. 263, 18621-18626.
20. Ramsey, A. J., and Fitzpatrick, P. F. (1998) Biochemistry 37, 8980-8986.
21. Cox, D. D., Benkovic, S. J., Bloom, L. M., Bradley, F. C., Nelson, M. J., Que, L., Jr., and Wallick, D. E. (1988) J. Am. Chem. Soc. 110, 2026-2032.
22. Sigel, H., and Martin, R. B. (1982) Chem. Rev. 82, 385-426.
23. Mandal, S. K., and Que, L., Jr. (1997) Inorg. Chem. 36, 5424-5425.
24. Hogan, D. A., Smith, S. R., Saari, E. A., McCracken, J., and Hausinger, R. P. (2000) J. Biol. Chem. 275, 12400-12409.
25. Khaleeli, N., Busby, R. W., and Townsend, C. A. (2000) Biochemistry 39, 8666-8673.
26. Jiang, H., Parales, R. E., Lynch, N. A., and Gibson, D. T. (1996) J. Bacteriol. 178, 3133-3139.
27. Borovok, I., Landman, O., Kreisberg-Zakarin, R., Aharonowitz, Y., and Cohen, G. (1996) Biochemistry 35, 1981-1987.
28. Doan, L. X., Hassan, A., Lipscomb, S. J., Dhanda, A., Zhang, Z., and Schofield, C. J. (2000) Biochem. Biophys. Res. Commun. 279, 240-244.
29. Sundaramoorthy, M., Choudhury, K., Edwards, S. L., and Poulos, T. L. (1991) J. Am. Chem. Soc. 113, 7755-7757.
30. Choudhury, K., Sundaramoorthy, M., Mauro, J. M., and Poulos, T. L. (1992) J. Biol. Chem. 267, 25656-25659.
31. Frantom, P. A., Pongdee, R., Sulikowski, G. A., and Fitzpatrick, P. A. (2002) J. Am. Chem. Soc. 124, 4202-4203.
32. Sono, M., Roach, M. P., Coulter, E. D., and Dawson, J. H. (1996) Chem. Rev. 96, 2841-2888.
33. Isaac, I. S., and Dawson, J. H. (1999) Essays Biochem. 34, 51-69.
34. Fitzpatrick, P. F. (1991) Biochemistry 30, 6386-6391.
35. Wasinger, E. C., Mitic, N., Hedman, B., Caradonna, J., Solomon, E. I., and Hodgson, K. O. (2002) Biochemistry 41, 6211-6217.
36. Andersen, O. A., Flatmark, T., and Hough, E. (2002) J. Mol. Biol. 320, 1095-1108.
37. Andersen, O. A., Flatmark, T., and Hough, E. (2001) J. Mol. Biol. 314, 279-291.
38. Goodwill, K. E., Sabatier, C., and Stevens, R. C. (1998) Biochemistry 37, 13437-13445.
39. Erlandsen, H., Flatmark, T., Stevens, R. C., and Hough, E. (1998) Biochemistry 37, 15638-15646.
40. Michaud-Soret, I., Andersson, K. K., Que, L., Jr., and Haavik, J. (1995) Biochemistry 34, 5504-5510.
41. El-Ayaan, U., Herlinger, E., Jameson, R. F., and Linert, W. (1997) J. Chem. Soc. 2813-2818.
42. Napolitano, A., Pezzella, A., and Prota, G. (1999) Chem. Res. Toxicol. 12, 1090-1097.
43. Jimenez, M., Garcia-Carmona, F., Garcia-Canovas, F., Iborra, J. L., Lozano, J. A., and Martinez, F. (1984) Arch. Biochem. Biophys. 235, 438-448.
44. Hastings, T. G., Lewis, D. A., and Zigmond, M. J. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 1956-1961.
45. Linert, W., Herlinger, E., Jameson, R. F., Kienzl, E., Jellinger, K., and Youdim, M. B. H. (1996) Biochim. Biophys. Acta 1316, 160-168.
46. Fitzpatrick, P. F. (2000) in Advances in Enzymology and Related Areas of Molecular Biology (Daniel L. Purich, Ed.) pp 235-294, John Wiley and Sons, Inc., New York.