High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin

Journal of Molecular Biology

Volumn 314, Issue 2, 2001, Pages 279-291

  Andersen, Ole Andreas ^a   Flatmark, Torgeir ^b   Hough, Edward ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b UNIVERSITY OF BERGEN   (Norway)

Author keywords

Ferrous iron; Iron ligands; Phenylalanine hydroxylase; Protein crystallography; Tetrahydrobiopterin

Indexed keywords

FERROUS ION; PHENYLALANINE 4 MONOOXYGENASE; PTERIN DERIVATIVE; TETRAHYDROBIOPTERIN;

ARTICLE; BINDING KINETICS; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; GEOMETRY; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0035941096     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5061     Document Type: Article

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