N-Thiolated β-lactam antibacterials: Effects of the N-organothio substituent on anti-MRSA activity

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 11, 2006, Pages 3775-3784

  Heldreth, Bart ^a   Long, Timothy E ^a   Jang, Seyoung ^a   Reddy, G Suresh Kumar ^a   Turos, Edward ^a   Dickey, Sonja ^a   Lim, Daniel V ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Antibiotics; MRSA; N Thiolated lactams; SAR

Indexed keywords

BETA LACTAM; GLUTATHIONE; SULFUR;

AGAR GEL DIFFUSION; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL STRAIN; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG SYNTHESIS; GROWTH INHIBITION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; OXIDATION; STEREOCHEMISTRY; STEREOISOMERISM;

ANTI-BACTERIAL AGENTS; BETA-LACTAMS; METHICILLIN RESISTANCE; MICROBIAL SENSITIVITY TESTS; MODELS, BIOLOGICAL; MOLECULAR CONFORMATION; STAPHYLOCOCCUS AUREUS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL COMPOUNDS;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

EID: 33646466336     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.01.029     Document Type: Article

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