메뉴 건너뛰기




Volumn 68, Issue 9, 2008, Pages 3350-3360

Frzb, a secreted Wnt antagonist, decreases growth and invasiveness of fibrosarcoma cells associated with inhibition of Met signaling

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN FRZB; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; WNT PROTEIN; FRZB PROTEIN; GELATINASE A; GLYCOPROTEIN; GROWTH FACTOR RECEPTOR; MET PROTEIN, HUMAN; ONCOPROTEIN; SMALL INTERFERING RNA;

EID: 44849108031     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-3220     Document Type: Article
Times cited : (69)

References (46)
  • 1
    • 23844442937 scopus 로고    scopus 로고
    • Soft tissue sarcomas in adults
    • Clark MA, Fisher C, Judson I, et al. Soft tissue sarcomas in adults. N Engl J Med 2005;353:701-11.
    • (2005) N Engl J Med , vol.353 , pp. 701-711
    • Clark, M.A.1    Fisher, C.2    Judson, I.3
  • 2
    • 19944403876 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling pathway as a novel cancer drug target
    • Luu HH, Zhang R, Haydon RC, et al. Wnt/β-catenin signaling pathway as a novel cancer drug target. Curr Cancer Drug Targets 2004;4:653-71.
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 653-671
    • Luu, H.H.1    Zhang, R.2    Haydon, R.C.3
  • 3
    • 27544496133 scopus 로고    scopus 로고
    • Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness
    • Zi X, Guo Y, Hoang BH, et al. Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness. Cancer Res 2005;65:9762-70.
    • (2005) Cancer Res , vol.65 , pp. 9762-9770
    • Zi, X.1    Guo, Y.2    Hoang, B.H.3
  • 4
    • 34447131518 scopus 로고    scopus 로고
    • The WNT5A/PKC pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors, and initiation of an epithelial to mesenchymal transition
    • Dissanayake SK, Wade MS, Johnson CE, et al. The WNT5A/PKC pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors, and initiation of an epithelial to mesenchymal transition. J Biol Chem 2007;28:17259-71.
    • (2007) J Biol Chem , vol.28 , pp. 17259-17271
    • Dissanayake, S.K.1    Wade, M.S.2    Johnson, C.E.3
  • 5
    • 0033547361 scopus 로고    scopus 로고
    • Predominance of β-catenin mutations and β-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor)
    • Tejpar S, Nollet F, Li C, et al. Predominance of β-catenin mutations and β-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor). Oncogene 1999;18:6615-20.
    • (1999) Oncogene , vol.18 , pp. 6615-6620
    • Tejpar, S.1    Nollet, F.2    Li, C.3
  • 6
    • 33745615817 scopus 로고    scopus 로고
    • Activation of Wnt signaling in the intestinal mucosa of Apc+/min mice does not cause overexpression of the receptor tyrosine kinase Met
    • Boon EM, Pouwels W, Redeker S, et al. Activation of Wnt signaling in the intestinal mucosa of Apc+/min mice does not cause overexpression of the receptor tyrosine kinase Met. Cancer Sci 2006;97:710-5.
    • (2006) Cancer Sci , vol.97 , pp. 710-715
    • Boon, E.M.1    Pouwels, W.2    Redeker, S.3
  • 7
    • 34249317261 scopus 로고    scopus 로고
    • Development of gastric tumors in Apc(Min/+) mice by the activation of the β-catenin/Tcf signaling pathway
    • Tomita H, Yamada Y, Oyama T, et al. Development of gastric tumors in Apc(Min/+) mice by the activation of the β-catenin/Tcf signaling pathway. Cancer Res 2007;67:4079-87.
    • (2007) Cancer Res , vol.67 , pp. 4079-4087
    • Tomita, H.1    Yamada, Y.2    Oyama, T.3
  • 8
    • 33847011428 scopus 로고    scopus 로고
    • Wnt inhibitory factor inhibits lung cancer cell growth
    • Kim J, You L, Xu Z, et al. Wnt inhibitory factor inhibits lung cancer cell growth. J Thorac Cardiovasc Surg 2007;133:733-7.
    • (2007) J Thorac Cardiovasc Surg , vol.133 , pp. 733-737
    • Kim, J.1    You, L.2    Xu, Z.3
  • 9
    • 34347230100 scopus 로고    scopus 로고
    • Wnt pathway and breast cancer
    • Mohinta S, Wu H, Chaurasia P, et al. Wnt pathway and breast cancer. Front Biosci 2007;12:4020-33.
    • (2007) Front Biosci , vol.12 , pp. 4020-4033
    • Mohinta, S.1    Wu, H.2    Chaurasia, P.3
  • 10
    • 0033052527 scopus 로고    scopus 로고
    • Frequent β-catenin abnormalities in bone and soft tissue tumors
    • Iwao K, Miyoshi Y, Nawa G, et al. Frequent β-catenin abnormalities in bone and soft tissue tumors. Jpn J Cancer Res 1999;90:205-9.
    • (1999) Jpn J Cancer Res , vol.90 , pp. 205-209
    • Iwao, K.1    Miyoshi, Y.2    Nawa, G.3
  • 11
    • 0036207723 scopus 로고    scopus 로고
    • APC mutations in synovial sarcomas
    • Saito T, Oda Y, Sakamoto A, et al. APC mutations in synovial sarcomas. J Pathol 2002;196:445-9.
    • (2002) J Pathol , vol.196 , pp. 445-449
    • Saito, T.1    Oda, Y.2    Sakamoto, A.3
  • 12
    • 28844448329 scopus 로고    scopus 로고
    • Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas
    • Nagayama S, Fukukawa C, Katagiri T, et al. Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas. Oncogene 2005;24:6201-12.
    • (2005) Oncogene , vol.24 , pp. 6201-6212
    • Nagayama, S.1    Fukukawa, C.2    Katagiri, T.3
  • 13
    • 26844569797 scopus 로고    scopus 로고
    • Efficacy of Wnt-1 monoclonal antibody in sarcoma cells
    • Mikami I, You L, He B, et al. Efficacy of Wnt-1 monoclonal antibody in sarcoma cells. BMC Cancer 2005;5:53-9.
    • (2005) BMC Cancer , vol.5 , pp. 53-59
    • Mikami, I.1    You, L.2    He, B.3
  • 14
    • 0029959105 scopus 로고    scopus 로고
    • Primary structure and tissue distribution of FRZB, a novel protein related to Drosophila frizzled, suggest a role in skeletal morphogenesis
    • Hoang B, Moos M, Jr., Luyten FP, et al. Primary structure and tissue distribution of FRZB, a novel protein related to Drosophila frizzled, suggest a role in skeletal morphogenesis. J Biol Chem 1996;271:26131-7.
    • (1996) J Biol Chem , vol.271 , pp. 26131-26137
    • Hoang, B.1    Moos Jr., M.2    Luyten, F.P.3
  • 15
    • 0030892061 scopus 로고    scopus 로고
    • FrzB, a secreted protein expressed in the Spermann organizer, binds and inhibits Wnt-8
    • Wang S, Krinks M, Lin K, et al. FrzB, a secreted protein expressed in the Spermann organizer, binds and inhibits Wnt-8. Cell 1997;88:757-66.
    • (1997) Cell , vol.88 , pp. 757-766
    • Wang, S.1    Krinks, M.2    Lin, K.3
  • 16
    • 0030933978 scopus 로고    scopus 로고
    • Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer
    • Leyns L, Bouwmeester T, Kim SH, et al. Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell 1997;88:747-56.
    • (1997) Cell , vol.88 , pp. 747-756
    • Leyns, L.1    Bouwmeester, T.2    Kim, S.H.3
  • 17
    • 34848913487 scopus 로고    scopus 로고
    • The functional genetic variant Arg324Gly of frizzled-related protein (FRZB) is associated with colorectal cancer risk
    • Epub Apr 9
    • Shanmugam KS, Brenner H, Hoffmeister M. et al. The functional genetic variant Arg324Gly of frizzled-related protein (FRZB) is associated with colorectal cancer risk. Carcinogenesis. Epub 2007 Apr 9.
    • (2007) Carcinogenesis
    • Shanmugam, K.S.1    Brenner, H.2    Hoffmeister, M.3
  • 18
    • 33845581657 scopus 로고    scopus 로고
    • Severe suppression of Frzb/sFRP3 transcription in osteogenic sarcoma
    • Mandal D, Srivastava A, Mahlum E, et al. Severe suppression of Frzb/sFRP3 transcription in osteogenic sarcoma. Gene 2007;386:131-8.
    • (2007) Gene , vol.386 , pp. 131-138
    • Mandal, D.1    Srivastava, A.2    Mahlum, E.3
  • 19
    • 18044386744 scopus 로고    scopus 로고
    • LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
    • Gong Y, Slee RB, Fukai N, et al. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 2001;107:513-23.
    • (2001) Cell , vol.107 , pp. 513-523
    • Gong, Y.1    Slee, R.B.2    Fukai, N.3
  • 20
    • 9244240664 scopus 로고    scopus 로고
    • Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-β-catenin pathway
    • Hoang BH, Kubo T, Gorlick R, et al. Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-β-catenin pathway. Cancer Res 2004;64:2734-9.
    • (2004) Cancer Res , vol.64 , pp. 2734-2739
    • Hoang, B.H.1    Kubo, T.2    Gorlick, R.3
  • 21
    • 0037162536 scopus 로고    scopus 로고
    • The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases
    • Tsai CN, Tsai CL, Tse KP, et al. The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases. Proc Natl Acad Sci U S A 2002;99:10084-9.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 10084-10089
    • Tsai, C.N.1    Tsai, C.L.2    Tse, K.P.3
  • 22
    • 0011701480 scopus 로고    scopus 로고
    • Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas
    • Ferracini R, Olivero M, Di Renzo MF, et al. Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas. Oncogene 1996;12:1697-705.
    • (1996) Oncogene , vol.12 , pp. 1697-1705
    • Ferracini, R.1    Olivero, M.2    Di Renzo, M.F.3
  • 23
    • 33646390939 scopus 로고    scopus 로고
    • MET overexpression turns human primary osteoblasts into osteosarcomas
    • Patane S, Avnet S, Coltella N, et al. MET overexpression turns human primary osteoblasts into osteosarcomas. Cancer Res 2006;66:4750-7.
    • (2006) Cancer Res , vol.66 , pp. 4750-4757
    • Patane, S.1    Avnet, S.2    Coltella, N.3
  • 24
    • 4043052971 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: Twist in development and metastasis
    • Kang Y, Massague J. Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 2004;118:277-9.
    • (2004) Cell , vol.118 , pp. 277-279
    • Kang, Y.1    Massague, J.2
  • 25
    • 33847268280 scopus 로고    scopus 로고
    • Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration
    • Wu B, Crampton SP, Hughes CC. Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration. Immunity 2007;26:227-39.
    • (2007) Immunity , vol.26 , pp. 227-239
    • Wu, B.1    Crampton, S.P.2    Hughes, C.C.3
  • 26
    • 0037090780 scopus 로고    scopus 로고
    • Promoter characterization of the novel human matrix metalloproteinase-26 gene: Regulation by the T-cell factor-4 implies specific expression of the gene in cancer cells of epithelial origin
    • Marchenko GN, Marchenko ND, Leng J, Strongin AY. Promoter characterization of the novel human matrix metalloproteinase-26 gene: regulation by the T-cell factor-4 implies specific expression of the gene in cancer cells of epithelial origin. Biochem J 2002;363:253-62.
    • (2002) Biochem J , vol.363 , pp. 253-262
    • Marchenko, G.N.1    Marchenko, N.D.2    Leng, J.3    Strongin, A.Y.4
  • 27
    • 23144455312 scopus 로고    scopus 로고
    • Matrix metalloproteinases participate in osteosarcoma invasion
    • Bjornlan K, Flatmark K, Pettersen S, et al. Matrix metalloproteinases participate in osteosarcoma invasion. J Surg Res 2005;127:151-6.
    • (2005) J Surg Res , vol.127 , pp. 151-156
    • Bjornlan, K.1    Flatmark, K.2    Pettersen, S.3
  • 28
    • 27644507899 scopus 로고    scopus 로고
    • RNAi mediated MMP-1 silencing inhibits human chondrosarcoma invasion
    • Yuan J, Dutton CM, Scully SP. RNAi mediated MMP-1 silencing inhibits human chondrosarcoma invasion. J Orthop Res 2005;23:1467-74.
    • (2005) J Orthop Res , vol.23 , pp. 1467-1474
    • Yuan, J.1    Dutton, C.M.2    Scully, S.P.3
  • 29
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signaling pathway
    • Kawano Y, Kypta R. Secreted antagonists of the Wnt signaling pathway. J Cell Sci 2003;116:2627-34.
    • (2003) J Cell Sci , vol.116 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 30
    • 0025764960 scopus 로고
    • c-met is amplified but not mutated in a cell line with an activated met tyrosine kinase
    • Ponzetto C, Giordano S, Peverali F, et al. c-met is amplified but not mutated in a cell line with an activated met tyrosine kinase. Oncogene 1991;6:553-9.
    • (1991) Oncogene , vol.6 , pp. 553-559
    • Ponzetto, C.1    Giordano, S.2    Peverali, F.3
  • 31
    • 0031668285 scopus 로고    scopus 로고
    • Coexpression of HGF and c-Met/HGF receptor in human bone and soft tissue tumors
    • Fukuda T, Ichimura E, Shinozaki T, et al. Coexpression of HGF and c-Met/HGF receptor in human bone and soft tissue tumors. Pathol Int 1998;48:757-62.
    • (1998) Pathol Int , vol.48 , pp. 757-762
    • Fukuda, T.1    Ichimura, E.2    Shinozaki, T.3
  • 32
    • 0028909659 scopus 로고
    • The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit
    • Ferracini R, Di Renzo MF, Scotlandi K, et al. The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit. Oncogene 1995;10:739-49.
    • (1995) Oncogene , vol.10 , pp. 739-749
    • Ferracini, R.1    Di Renzo, M.F.2    Scotlandi, K.3
  • 34
    • 0034006675 scopus 로고    scopus 로고
    • Van der Voort, Taher TE, Derksen PW, et al. The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation. Adv Cancer Res 2000;79:39-90.
    • Van der Voort, Taher TE, Derksen PW, et al. The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation. Adv Cancer Res 2000;79:39-90.
  • 35
    • 33646404053 scopus 로고    scopus 로고
    • Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma
    • Taulli R, Scuoppo C, Bersani F, et al. Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma. Cancer Res 2006;66:4742-9.
    • (2006) Cancer Res , vol.66 , pp. 4742-4749
    • Taulli, R.1    Scuoppo, C.2    Bersani, F.3
  • 36
    • 0036888309 scopus 로고    scopus 로고
    • Cytoplasmic and/or nuclear accumulation of the β-catenin protein is a frequent event in human osteosarcoma
    • Haydon RC, Deyrup A, Ishikawa A, et al. Cytoplasmic and/or nuclear accumulation of the β-catenin protein is a frequent event in human osteosarcoma. Int J Cancer 2002;102:338-42.
    • (2002) Int J Cancer , vol.102 , pp. 338-342
    • Haydon, R.C.1    Deyrup, A.2    Ishikawa, A.3
  • 37
    • 33749588194 scopus 로고    scopus 로고
    • Hypermethylation of the APC promoter but lack of APC mutations in myxoid/round-cell liposarcoma
    • Sievers S, Fritzsch C, Lehnhardt M, et al. Hypermethylation of the APC promoter but lack of APC mutations in myxoid/round-cell liposarcoma. Int J Cancer 2006;119:2347-52.
    • (2006) Int J Cancer , vol.119 , pp. 2347-2352
    • Sievers, S.1    Fritzsch, C.2    Lehnhardt, M.3
  • 38
    • 33749024777 scopus 로고    scopus 로고
    • Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
    • Christiansen JJ, Rajasekaran AK. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res 2006;66:8319-26.
    • (2006) Cancer Res , vol.66 , pp. 8319-8326
    • Christiansen, J.J.1    Rajasekaran, A.K.2
  • 39
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • Huber MA, Kraut N, Beug H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol 2005;17:548-58.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 40
    • 34447279476 scopus 로고    scopus 로고
    • Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells
    • Guo Y, Zi X, Hoang BH, et al. Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells. J Orthop Res 2007;25:964-71.
    • (2007) J Orthop Res , vol.25 , pp. 964-971
    • Guo, Y.1    Zi, X.2    Hoang, B.H.3
  • 41
    • 0035839534 scopus 로고    scopus 로고
    • Cloning and characterization of three Xenopus Slug promoters reveal direct regulation by Lef/β-catenin signaling
    • Vallin J, Thuret R, Giacomello E, et al. Cloning and characterization of three Xenopus Slug promoters reveal direct regulation by Lef/β-catenin signaling. J Biol Chem 2001;276:30350-8.
    • (2001) J Biol Chem , vol.276 , pp. 30350-30358
    • Vallin, J.1    Thuret, R.2    Giacomello, E.3
  • 42
    • 0345700653 scopus 로고    scopus 로고
    • Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation
    • Howe LR, Watanabe O, Leonard J, Brown AM. Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation. Cancer Res 2003;63:1906-13.
    • (2003) Cancer Res , vol.63 , pp. 1906-1913
    • Howe, L.R.1    Watanabe, O.2    Leonard, J.3    Brown, A.M.4
  • 43
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • Coussens LM, Fingleton B, Matrisian LM. Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 2002;295:2387-92.
    • (2002) Science , vol.295 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 44
    • 34249340106 scopus 로고    scopus 로고
    • Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice
    • Taniwaki K, Fukamachi H, Komori, et al. Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice. Cancer Res 2007;67:4311-9.
    • (2007) Cancer Res , vol.67 , pp. 4311-4319
    • Taniwaki, K.1    Fukamachi, H.2    Komori3
  • 45
    • 26444495099 scopus 로고    scopus 로고
    • Frequent genomic abnormalities at TWIST in human pediatric osteosarcomas
    • Entz-Werle N, Stoetzel C, Berard-Marec P, et al. Frequent genomic abnormalities at TWIST in human pediatric osteosarcomas. Int J Cancer 2005;117:349-55.
    • (2005) Int J Cancer , vol.117 , pp. 349-355
    • Entz-Werle, N.1    Stoetzel, C.2    Berard-Marec, P.3
  • 46
    • 34347254641 scopus 로고    scopus 로고
    • The soluble Wnt receptor frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
    • Dealmeida VI, Li M, Ernst JA, et al. The soluble Wnt receptor frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo. Cancer Res 2007;67:5371-9.
    • (2007) Cancer Res , vol.67 , pp. 5371-5379
    • Dealmeida, V.I.1    Li, M.2    Ernst, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.