-
1
-
-
0025899162
-
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
-
Nishisho I, Nakamura Y, Miyoshi Y, et al. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 1991;253:665-9.
-
(1991)
Science
, vol.253
, pp. 665-669
-
-
Nishisho, I.1
Nakamura, Y.2
Miyoshi, Y.3
-
2
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler KW, Nilbert MC, Su LK, et al. Identification of FAP locus genes from chromosome 5q21. Science 1991; 253:661-5.
-
(1991)
Science
, vol.253
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.K.3
-
3
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87:159-70.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
4
-
-
0030975671
-
Constitutive transcriptional activation by a β-catenin-Tcf complex in APC-/- colon carcinoma
-
Korinek V, Barker N, Morin PJ, et al. Constitutive transcriptional activation by a β-catenin-Tcf complex in APC-/- colon carcinoma. Science 1997;275:1784-7.
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
-
5
-
-
0030949463
-
Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
-
Morin PJ, Sparks AB, Korinek V, et al. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science 1997;275:1787-90.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
-
6
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14:1837-51.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
8
-
-
0030900696
-
Stabilization of β-catenin by genetic defects in melanoma cell lines
-
Rubinfeld B, Robbins P, El-Gamil M, Albert I, Porfiri E, Polakis P. Stabilization of β-catenin by genetic defects in melanoma cell lines. Science 1997;275:1790-2.
-
(1997)
Science
, vol.275
, pp. 1790-1792
-
-
Rubinfeld, B.1
Robbins, P.2
El-Gamil, M.3
Albert, I.4
Porfiri, E.5
Polakis, P.6
-
9
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He TC, Sparks AB, Rago C, et al. Identification of c-MYC as a target of the APC pathway. Science 1998;281: 1509-12.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
-
10
-
-
0033119801
-
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu O, McCormick F. β-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999; 398:422-6.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
12
-
-
33749345198
-
Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway
-
Oshima H, Matsunaga A, Fujimura T, Tsukamoto T, Taketo MM, Oshima M. Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway. Gastroenterology 2006;131:1086-95.
-
(2006)
Gastroenterology
, vol.131
, pp. 1086-1095
-
-
Oshima, H.1
Matsunaga, A.2
Fujimura, T.3
Tsukamoto, T.4
Taketo, M.M.5
Oshima, M.6
-
13
-
-
0037096887
-
β-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer
-
Clements WM, Wang J, Sarnaik A, et al. β-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer. Cancer Res 2002;62:3503-6.
-
(2002)
Cancer Res
, vol.62
, pp. 3503-3506
-
-
Clements, W.M.1
Wang, J.2
Sarnaik, A.3
-
14
-
-
0035916970
-
Altered expression and mutation of β-catenin gene in gastric carcinomas and cell lines
-
Woo DK, Kim HS, Lee HS, Kang YH, Yang HK, Kim WH. Altered expression and mutation of β-catenin gene in gastric carcinomas and cell lines. Int J Cancer 2001;95:108-13.
-
(2001)
Int J Cancer
, vol.95
, pp. 108-113
-
-
Woo, D.K.1
Kim, H.S.2
Lee, H.S.3
Kang, Y.H.4
Yang, H.K.5
Kim, W.H.6
-
16
-
-
0036966399
-
Inverse relationship between APC gene mutation in gastric-adenomas and development of adenocarcinoma
-
Lee JH, Abraham SC, Kim HS, et al. Inverse relationship between APC gene mutation in gastric-adenomas and development of adenocarcinoma. Am J Pathol 2002;161:611-8.
-
(2002)
Am J Pathol
, vol.161
, pp. 611-618
-
-
Lee, J.H.1
Abraham, S.C.2
Kim, H.S.3
-
17
-
-
0036193127
-
Increased β-catenin mRNA levels and mutational alterations of the APC and β-catenin gene are present in intestinal-type gastric cancer
-
Ebert MP, Fei G, Kallmann S, et al. Increased β-catenin mRNA levels and mutational alterations of the APC and β-catenin gene are present in intestinal-type gastric cancer. Carcinogenesis 2002;23:87-91.
-
(2002)
Carcinogenesis
, vol.23
, pp. 87-91
-
-
Ebert, M.P.1
Fei, G.2
Kallmann, S.3
-
18
-
-
0026734665
-
The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer
-
Horii A, Nakatsuru S, Miyoshi Y, et al. The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer. Cancer Res 1992; 52:3231-3.
-
(1992)
Cancer Res
, vol.52
, pp. 3231-3233
-
-
Horii, A.1
Nakatsuru, S.2
Miyoshi, Y.3
-
19
-
-
0023924052
-
Upper gastrointestinal cancer in familial adenomatous polyposis
-
Jagelman DG, DeCosse JJ, Bussey HJ. Upper gastrointestinal cancer in familial adenomatous polyposis. Lancet 1988;1:1149-51.
-
(1988)
Lancet
, vol.1
, pp. 1149-1151
-
-
Jagelman, D.G.1
DeCosse, J.J.2
Bussey, H.J.3
-
20
-
-
0026537747
-
The risk of upper gastrointestinal cancer in familial adenomatous polyposis
-
Offerhaus GJ, Giardiello FM, Krush AJ, et al. The risk of upper gastrointestinal cancer in familial adenomatous polyposis. Gastroenterology 1992;102:1980-2.
-
(1992)
Gastroenterology
, vol.102
, pp. 1980-1982
-
-
Offerhaus, G.J.1
Giardiello, F.M.2
Krush, A.J.3
-
21
-
-
0027461243
-
The impact of familial adenomatous polyposis on the tumorigenesis and mortality at the several organs. Its rational treatment
-
Iwama T, Mishima Y, Utsunomiya J. The impact of familial adenomatous polyposis on the tumorigenesis and mortality at the several organs. Its rational treatment. Ann Surg 1993;217:101-8.
-
(1993)
Ann Surg
, vol.217
, pp. 101-108
-
-
Iwama, T.1
Mishima, Y.2
Utsunomiya, J.3
-
22
-
-
0029761476
-
Risk of cxtracolonic cancer in familial adenomatous polyposis
-
Nugent KP, Spigelman AD, Phillips RK. Risk of cxtracolonic cancer in familial adenomatous polyposis. Br J Surg 1996;83:1121-2.
-
(1996)
Br J Surg
, vol.83
, pp. 1121-1122
-
-
Nugent, K.P.1
Spigelman, A.D.2
Phillips, R.K.3
-
23
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
Moser AR, Pitot HC, Dove WF. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 1990;247:322-4.
-
(1990)
Science
, vol.247
, pp. 322-324
-
-
Moser, A.R.1
Pitot, H.C.2
Dove, W.F.3
-
25
-
-
0029047954
-
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
-
Oshima M, Oshima H, Kitagawa K, Kobayashi M, Itakura C, Taketo M. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc Natl Acad Sci U S A 1995;92:4482-6.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 4482-4486
-
-
Oshima, M.1
Oshima, H.2
Kitagawa, K.3
Kobayashi, M.4
Itakura, C.5
Taketo, M.6
-
26
-
-
0030776228
-
Mice carrying a truncated Apc gene have diminished gastric epithelial proliferation, gastric inflammation, and humoral immunity in response to Helicobacter felis infection
-
Fox JG, Dangler CA, Whary MT, Edelman W, Kucherlapati R, Wang TC. Mice carrying a truncated Apc gene have diminished gastric epithelial proliferation, gastric inflammation, and humoral immunity in response to Helicobacter felis infection. Cancer Res 1997;57:3972-8.
-
(1997)
Cancer Res
, vol.57
, pp. 3972-3978
-
-
Fox, J.G.1
Dangler, C.A.2
Whary, M.T.3
Edelman, W.4
Kucherlapati, R.5
Wang, T.C.6
-
27
-
-
0031568788
-
A mouse model of human familial adenomatous polyposis
-
Yang K, Edelmann W, Fan K, et al. A mouse model of human familial adenomatous polyposis. J Exp Zool 1997;277:245-54.
-
(1997)
J Exp Zool
, vol.277
, pp. 245-254
-
-
Yang, K.1
Edelmann, W.2
Fan, K.3
-
28
-
-
13244273712
-
Fox11 is a mesenchymal modifier of Min in carcinogenesis of stomach and colon
-
Perreault N, Sackett SD, Katz JP, Furth EE, Kaestner KH. Fox11 is a mesenchymal modifier of Min in carcinogenesis of stomach and colon. Genes Dev 2005;19:311-5.
-
(2005)
Genes Dev
, vol.19
, pp. 311-315
-
-
Perreault, N.1
Sackett, S.D.2
Katz, J.P.3
Furth, E.E.4
Kaestner, K.H.5
-
29
-
-
7444238266
-
Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice
-
Mutoh H, Sakurai S, Satoh K, et al. Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice. Cancer Res 2004;64:7740-7.
-
(2004)
Cancer Res
, vol.64
, pp. 7740-7747
-
-
Mutoh, H.1
Sakurai, S.2
Satoh, K.3
-
30
-
-
24044487605
-
Generation of a unique strain of multiple intestinal neoplasia (Apc(+/Min-FCCC)) mice with significantly increased numbers of colorectal adenomas
-
Cooper HS, Chang WC, Coudry R, et al. Generation of a unique strain of multiple intestinal neoplasia (Apc(+/Min-FCCC)) mice with significantly increased numbers of colorectal adenomas. Mol Carcinog 2005; 44:31-41.
-
(2005)
Mol Carcinog
, vol.44
, pp. 31-41
-
-
Cooper, H.S.1
Chang, W.C.2
Coudry, R.3
-
31
-
-
10044221016
-
Colorectal cancers in a new mouse model of familial adenomatous polyposis: Influence of genetic and environmental modifiers
-
Colnot S, Niwa-Kawakita M, Hamard G, et al. Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers. Lab Invest 2004;84: 1619-30.
-
(2004)
Lab Invest
, vol.84
, pp. 1619-1630
-
-
Colnot, S.1
Niwa-Kawakita, M.2
Hamard, G.3
-
32
-
-
0032897353
-
Chemoprevention of intestinal adenomas in the ApcMin mouse by piroxicam: Kinetics, strain effects and resistance to chemosuppression
-
Ritland SR, Gendler SJ. Chemoprevention of intestinal adenomas in the ApcMin mouse by piroxicam: kinetics, strain effects and resistance to chemosuppression. Carcinogenesis 1999;20:51-8.
-
(1999)
Carcinogenesis
, vol.20
, pp. 51-58
-
-
Ritland, S.R.1
Gendler, S.J.2
-
33
-
-
0030903037
-
Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice
-
Wasan HS, Novelli M, Bee J, Bodmer WF. Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice. Proc Natl Acad Sci U S A 1997;94:3308-13.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 3308-3313
-
-
Wasan, H.S.1
Novelli, M.2
Bee, J.3
Bodmer, W.F.4
-
34
-
-
0031959559
-
N-methyl-N- nitrosourea concentration-dependent, rather than total intake-dependent, induction of adenocarcinomas in the glandular stomach of BALB/c mice
-
Yamachika T, Nakanishi H, Inada K, et al. N-methyl-N- nitrosourea concentration-dependent, rather than total intake-dependent, induction of adenocarcinomas in the glandular stomach of BALB/c mice. Jpn J Cancer Res 1998;89:385-91.
-
(1998)
Jpn J Cancer Res
, vol.89
, pp. 385-391
-
-
Yamachika, T.1
Nakanishi, H.2
Inada, K.3
-
35
-
-
21144439861
-
Chemopreventive effect of peroxisome proliferator-activated receptor γ on gastric carcinogenesis in mice
-
Lu J, Imamura K, Nomura S, et al. Chemopreventive effect of peroxisome proliferator-activated receptor γ on gastric carcinogenesis in mice. Cancer Res 2005;65: 4769-74.
-
(2005)
Cancer Res
, vol.65
, pp. 4769-4774
-
-
Lu, J.1
Imamura, K.2
Nomura, S.3
-
36
-
-
0037370137
-
Pathology of mouse models of intestinal cancer: Consensus report and recommendations
-
Boivin GP, Washington K, Yang K, et al. Pathology of mouse models of intestinal cancer: consensus report and recommendations. Gastroenterology 2003;124: 762-77.
-
(2003)
Gastroenterology
, vol.124
, pp. 762-777
-
-
Boivin, G.P.1
Washington, K.2
Yang, K.3
-
37
-
-
9744251631
-
The selective cyclooxygenase-2 inhibitor nimesulide prevents Helicobacter pylori-associated gastric cancer development in a mouse model
-
Nam KT, Hahm KB, Oh SY, et al. The selective cyclooxygenase-2 inhibitor nimesulide prevents Helicobacter pylori-associated gastric cancer development in a mouse model. Clin Cancer Res 2004;10:8105-13.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8105-8113
-
-
Nam, K.T.1
Hahm, K.B.2
Oh, S.Y.3
-
38
-
-
0037112430
-
Microadenomatous lesions involving loss of Apc heterozygosity in the colon of adult Apc(Min/+) mice
-
Yamada Y, Hata K, Hirose Y, et al. Microadenomatous lesions involving loss of Apc heterozygosity in the colon of adult Apc(Min/+) mice. Cancer Res 2002; 62:6367-70.
-
(2002)
Cancer Res
, vol.62
, pp. 6367-6370
-
-
Yamada, Y.1
Hata, K.2
Hirose, Y.3
-
39
-
-
26444473234
-
Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis
-
Yamada Y, Jackson-Grusby L, Linhart H, et al. Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. Proc Natl Acad Sci U S A 2005;102:13580-5.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13580-13585
-
-
Yamada, Y.1
Jackson-Grusby, L.2
Linhart, H.3
-
40
-
-
24144455997
-
Inflammation, atrophy, gastric cancer: Connecting the molecular dots
-
Merchant JL. Inflammation, atrophy, gastric cancer: connecting the molecular dots. Gastroenterology 2005; 129:1079-82.
-
(2005)
Gastroenterology
, vol.129
, pp. 1079-1082
-
-
Merchant, J.L.1
-
41
-
-
26444528395
-
Gene deregulation in gastric cancer
-
Stock M, Otto F. Gene deregulation in gastric cancer. Gene 2005;360:1-19.
-
(2005)
Gene
, vol.360
, pp. 1-19
-
-
Stock, M.1
Otto, F.2
-
42
-
-
0026562404
-
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
-
Su LK, Kinzler KW, Vogelstein B, et al. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 1992;256: 668-70.
-
(1992)
Science
, vol.256
, pp. 668-670
-
-
Su, L.K.1
Kinzler, K.W.2
Vogelstein, B.3
-
43
-
-
0042886962
-
Control of gut differentiation and intestinal-type gastric carcinogenesis
-
Yuasa Y. Control of gut differentiation and intestinal-type gastric carcinogenesis. Nat Rev Cancer 2003;3:592-600.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 592-600
-
-
Yuasa, Y.1
-
44
-
-
0033790792
-
p53 knockout mice (-/-) are more susceptible than (+/-) or (+/+) mice to N-methyl-N-nitrosourea stomach carcinogenesis
-
Yamamoto M, Tsukamoto T, Sakai H, et al. p53 knockout mice (-/-) are more susceptible than (+/-) or (+/+) mice to N-methyl-N-nitrosourea stomach carcinogenesis. Carcinogenesis 2000;21:1891-7.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1891-1897
-
-
Yamamoto, M.1
Tsukamoto, T.2
Sakai, H.3
-
45
-
-
0036119151
-
Helicobacter pylori does not promote N-methyl-N-nitrosourea-induced gastric carcinogenesis in SPF C57BL/6 mice
-
Nakamura Y, Sakagami T, Yamamoto N, et al. Helicobacter pylori does not promote N-methyl-N-nitrosourea-induced gastric carcinogenesis in SPF C57BL/6 mice. Jpn J Cancer Res 2002;93:111-6.
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 111-116
-
-
Nakamura, Y.1
Sakagami, T.2
Yamamoto, N.3
-
46
-
-
0036091796
-
Helicobacter pylori infection promotes gastric carcinogenesis in a mice model
-
Han SU, Kim YB, Joo HJ, et al. Helicobacter pylori infection promotes gastric carcinogenesis in a mice model. J Gastroenterol Hepatol 2002;17:253-61.
-
(2002)
J Gastroenterol Hepatol
, vol.17
, pp. 253-261
-
-
Han, S.U.1
Kim, Y.B.2
Joo, H.J.3
-
47
-
-
0037188430
-
Independent variation in susceptibilities of six different mouse strains to induction of pepsinogen-altered pyloric glands and gastric tumor intestinalization by N-methyl-N-nitrosourea
-
Yamamoto M, Furihata C, Ogiu T, et al. Independent variation in susceptibilities of six different mouse strains to induction of pepsinogen-altered pyloric glands and gastric tumor intestinalization by N-methyl-N-nitrosourea. Cancer Lett 2002; 179:121-32.
-
(2002)
Cancer Lett
, vol.179
, pp. 121-132
-
-
Yamamoto, M.1
Furihata, C.2
Ogiu, T.3
-
48
-
-
0345768487
-
β Catenin mutations and nuclear accumulation during progression of rat stomach adenocarcinomas
-
Tsukamoto T, Yamamoto M, Ogasawara N, et al. β Catenin mutations and nuclear accumulation during progression of rat stomach adenocarcinomas. Cancer Sci 2003;94:1046-51.
-
(2003)
Cancer Sci
, vol.94
, pp. 1046-1051
-
-
Tsukamoto, T.1
Yamamoto, M.2
Ogasawara, N.3
-
49
-
-
0038736681
-
No involvement of β-catenin gene mutation in gastric carcinomas induced by N-methyl-N-nitrosourea in male F344 rats
-
Shimizu M, Suzui M, Moriwaki H, Mori H, Yoshimi N. No involvement of β-catenin gene mutation in gastric carcinomas induced by N-methyl-N-nitrosourea in male F344 rats. Cancer Lett 2003;195:147-52.
-
(2003)
Cancer Lett
, vol.195
, pp. 147-152
-
-
Shimizu, M.1
Suzui, M.2
Moriwaki, H.3
Mori, H.4
Yoshimi, N.5
-
50
-
-
3042549485
-
7beta;-Catenin gene alteration in glandular stomach adenocarcinomas in N-methyl-N-nitrosourea- treated and Helicobacter pylori-infected Mongolian gerbils
-
Cao X, Tsukamoto T, Nozaki K, et al. 7beta;-Catenin gene alteration in glandular stomach adenocarcinomas in N-methyl-N-nitrosourea- treated and Helicobacter pylori-infected Mongolian gerbils. Cancer Sci 2004;95:487-90.
-
(2004)
Cancer Sci
, vol.95
, pp. 487-490
-
-
Cao, X.1
Tsukamoto, T.2
Nozaki, K.3
|