Investigation of the release of aspirin from spray-congealed micro-pellets

Journal of Microencapsulation

Volumn 22, Issue 3, 2005, Pages 245-251

  Guo, Q Y ^a   Chan, L W ^a   Heng, P W S ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Aspirin; Drug release; Hydrogenated soybean oil; Micro pellets; Spray congealing

Indexed keywords

ACETYLSALICYLIC ACID; HYDROGENATED VEGETABLE OIL; SOYBEAN OIL;

ARTICLE; CONTROLLED DRUG RELEASE; DRUG FORMULATION; DRUG MANUFACTURE; DRUG PELLET; DRUG SOLUBILITY; MICROENCAPSULATION; PARTICLE SIZE; SPRAY CONGEALING;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CAPSULES; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; HYDROGEN-ION CONCENTRATION; MODELS, THEORETICAL; PARTICLE SIZE;

EID: 22244445161     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652040500100345     Document Type: Article

References (7)

1. Adeyeye CM, Price JC. 1994. Development and evaluation of sustained-release ibuprofen-wax microspheres. II. In vitro dissolution studies. Pharmaceutical Research 11:575-579.
2. Cusimano AG, Becker CH. 1968. Spray-congealed formulations of sulfaethylthiadiazole (SETD) and waxed for prolonged-release medication. Journal of Pharmaceutical Sciences 57:1104-1112.
3. Deasy PB. 1984. General introduction. In: Deasy PB, editor. Microencapsulation and related drug processes. New York: Marcel Dekker, 181-193.
4. Fahmy R, Marmane W, Bensley DJ, Hollenbeck RG. 2001. Dissolution testing of aspirin boluses. Dissolution Technologies 8:1-4.
5. Hincal AA, Kaş HS. 1994. Preparation of micropellets by spray congealing. In: Ghebre-Sellassie I, editor. Multiparticulate oral drug delivery. New York: Marcel Dekker, 17-34.
6. Raghunathan Y, Becker CH. 1968. Spray-congealed formulations of sulfaethidole (SETD) and waxes for prolonged-release medication. Journal of Pharmaceutical Sciences 57:1748-1755.
7. Rodriguez L, Passerini N, Cavallari C, Cini M, Sancin P, Fini A. 1999. Description and preliminary evaluation of a new ultrasonic atomiser for spray-congealing processes. International Journal of Pharmaceutics 183:133-143.