Rheology of polyol behenates and drug release from matrix monolithic capsules

International Journal of Pharmaceutics

Volumn 182, Issue 2, 1999, Pages 145-154

  Duclos, R ^a   Bourret, E ^b   Brossard, C ^c  

^a UNIVERSITÉ DE ROUEN   (France)

^b CNRS   (France)

^c UNIVERSITY OF LIMOGES   (France)

Author keywords

Diffusion; Lipidic matrix; Monolithic capsules; Polyol behenates; Rheology

Indexed keywords

BEHENIC ACID; COMPRICOAT; COMPRITOL HD5; FATTY ACID DERIVATIVE; GLYCEROL BEHENATE; POLYOL; PROXYPHYLLINE; UNCLASSIFIED DRUG; WAX;

ARTICLE; DIFFUSION; DRUG CAPSULE; DRUG RELEASE; FLOW KINETICS; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSPENSION;

AMINOPHYLLINE; CAPSULES; FATTY ACIDS; PARTICLE SIZE; POLYMERS; SOLUBILITY; SUSPENSIONS; VISCOSITY;

EID: 0032998249     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00032-0     Document Type: Article

References (32)

1. Abdallah O.Y. Evaluation of some lipophilic materials as release controlling fillers for the development of ibuprofen formulations. Alexander J. Pharm. Sci. 6:1992;243-246.
2. Ausseur, T., Vignoles, P., Farah, N., Brossard, C., 1998. Theophylline extended release from waxy matrix granules obtained by melt granulation. Proceedings of the Second World Meeting APGI/APV. Paris, pp. 293-294.
3. Baykara T., Yüksel N. The preparation of prolonged action formulations in the form of semi solid matrix into hard gelatin capsules of oxprenolol. II. Thixocap method. Drug Dev. Ind. Pharm. 18:1992;233-243.
4. Bonferoni M.C., Caramella C., Sangalli M.E., Conte U., Hernandez R.M., Pedraz J.L. Rheological behaviour of hydrophilic polymers and drug release from erodible matrices. J. Control. Release. 18:1992;205-212.
5. Bourret E., Ratsimbazafy V., Maury L., Brossard C. Rheological behaviour of saturated polyglycolysed glycerides. J. Pharm. Pharmacol. 46:1994;538-541.
6. Brossard C., Wouessidjewe D. Contrôle de dissolution des formes pharmaceutiques orales solides à libération ralentie. Stp Pharma. 6:1990;728-741.
7. Brossard C., Lefort des Ylouses D., Duchêne D., Puisieux F., Carstensen J.T. Dissolution of a soluble drug substance from vinyl polymer matrices. J. Pharm. Sci. 72:1983;162-169.
8. Brossard,C., Bourret, E., Duclos, R., Ratsimbazafy, V., 1994. Rheology of drug suspensions in Gelucire mixtures and relationship with the release from matrix capsules. Proceedings of the International Symposium on Controlled Release of Bioactive Material, Vol. 21, pp. 770-771.
9. El-Sayed G.M., El-Said Y., Meshali M.M., Schwartz J.B. Kinetics of theophylline release from different tablet matrices. Stp Pharma Sci. 6:1996;390-397.
10. Fabregas J.L. Softening of semisynthetic suppository bases. Drug Dev. Ind. Pharm. 17:1991;1083-1096.
11. Gaudy, D., Ortigosa, C., Jacob, M., Puech, A., 1989. Corrélation entre viscosité et lyodisponibilité de gélules pâteuses: cas des polyéthylènes glycols. Proceedings of the International Conference of Pharmaceutical Technology. Paris, APGI, Vol. 5(3), pp. 179-189.
12. Hawley A.R., Rowley G., Lough W.J., Chatham S. Physical and chemical characterization of thermosoftened bases for molten filled hard gelatin capsule formulation. Drug Dev. Ind. Pharm. 18:1992;1719-1739.
13. Joachim, J., Abramovici, B., Joachim, G., Gaudy, D., 1994. Les matrices des Compritols. Etude in vitro-in vivo. Proceedings Rencontres Galéniques de Rabat, Vol. 1, pp. 37-47.
14. Joachim J., Cauture E., Prinderre P., Farah N., Laforêt J.P., Barthelemy P. A hot melt coating agent for controlled-release theophylline dosage forms. Pharm. Manuf. Rev. 8(3):1996;24-28.
15. Kaloustian J., Pauli A.M., Pastor J., Joachim J. Analyse thermique de mélanges binaires matrice lipidique/principe actif (15/85). Stp Pharma Sci. 5:1995;139-144.
16. Kopcha M., Lordi N., Tojo K.J. Evaluation of release from selected thermosoftening vehicles. J. Pharm. Pharmacol. 43:1991;382-387.
17. Margarit M.V., Rodriguez I.C., Cerezo A. Rheological study of rectal formulations of sodium valproate. Drug Dev. Ind. Pharm. 18:1992;79-92.
18. Massin V., Recq A., Thomas C. Etude du Précirol et du Compritol pour la formulation de capsules dures à libération modifiée. Bull. Tech. Gattefossé 75:1982;51-56.
19. Meshali M.M., El-Sayed G.M., Abd El-Aleem H.M., El-Said Y. Optimization of theophylline release from tablets containing Compritol. Stp Pharma Sci. 5:1995;429-434.
20. Mouricout A.M., Gerbaud D., Brossard C., Lefort des Ylouses D. Gélules à matrice semi-solide de Gélucire: lyodisponibilité et étude structurale. Stp Pharma. 6:1990;368-375.
21. Otsuka M., Matsuda Y. Programmable drug release of highly water-soluble pentoxifylline from dry-coated wax matrix tablets. J. Pharm. Sci. 84:1995;443-447.
22. Pelletier, P., Gaudy, D., Abramovici, B., Ruiz, J.M., Reynier, J.P., Joachim, J., 1992. Etude de l'activité prolongée de trois matrices lipidiques en compression selon un plan d'expérience et par analyse des données. Proceedings of the International Conference of Pharmaceutical Technology. Paris, APGI, Vol. 6(3), pp. 305-313.
23. Perez M.A., Ghaly E.S., Marti A. Sustained release phenylpropanolamine hydrochloride from Ato 888 matrix. Puerto Rico Health Sci. J. 12:1993;263-267.
24. Ratsimbazafy V., Brossard C. Les Gélucire et le ralentissement de la libération des principes actifs. Stp Pharma Prat. 1:1991;335-349.
25. Ratsimbazafy V., Bourret E., Brossard C. Drug release from matrix tablets and minitablets containing glycerides. Pharm. Ind. 58:1996;442-446.
26. Ratsimbazafy V., Bourret E., Brossard C. Effect of formulation on the rheology of theophylline compound suspensions in Gelucires. J. Pharm. Pharmacol. 49:1997;852-857.
27. Ritger P.L., Peppas N.A. A simple equation for description of solute release. I - Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J. Control. Release. 5:1987;23-26.
28. Shah N.H., Phuapradit W., Ahmed H. Liquid /semi-solid filling in hard gelatin capsules: formulation and processing considerations. Bull. Tech. Gattefossé 89:1996;27-37.
29. Sutananta W., Craig D.Q.M., Newton J.M. An investigation into the effects of preparation conditions and storage on the rate of drug release from pharmaceutical glyceride bases. J. Pharm. Pharmacol. 47:1995;355-359.
30. Thomsen L.J., Schaefer T., Kristensen H.G. Prolonged release matrix pellets prepared by melt pelletization 2: hydrophobic substances as meltable binders. Drug Dev. Ind. Pharm. 20:1994;1179-1197.
31. Wan L.S.C., Heng P.W.S., Wong L.F. Relationship between polymer viscosity and drug release from a matrix system. Pharm. Res. 11:1992;1510-1514.
32. Yolou S., Delarbre J.L., Bourret E., Maury L., Abramovici B., Joachim J. Caractérisation physico-chimique d'excipients polymériques: les Gélucires Compritol 888, Compritol HD5 ATO et du lubrifiant WL 3284 ATO. Pharm. Acta Helv. 67 (Suppl):1992;25-29.