A mathematical model to predict the size of the pellets formed in freeze pelletization techniques: Parameters affecting pellet size

Journal of Pharmaceutical Sciences

Volumn 95, Issue 1, 2006, Pages 167-180

  Cheboyina, Sreekhar ^a   O'Haver, John ^b   Wyandt, Christy M ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b The University of Mississippi   (United States)

Author keywords

Drop formation; Freeze pelletization; Interfacial tension; Mathematical model; Needle gauge size; Particle size; Pellets; Processing; Surface chemistry; Viscosity

Indexed keywords

GLYCEROL; MACROGOL; SILICONE OIL; WAX; DIACYLGLYCEROL; GLYCEROL PALMITOSTEARATE; MACROGOL DERIVATIVE;

AQUEOUS SOLUTION; ARTICLE; DENSITY; DRUG FORMULATION; DRUG MANUFACTURE; FREEZE PELLETIZATION; FREEZING; LIQUID; MATHEMATICAL MODEL; NEEDLE; PARTICLE SIZE; PELLET EXTRUSION; PELLET SIZE; PHARMACEUTICAL ENGINEERING; SURFACE TENSION; TECHNIQUE; VALIDATION STUDY; VISCOSITY; CHEMISTRY; DRUG DOSAGE FORM; INSTRUMENTATION; METHODOLOGY; TEMPERATURE; THEORETICAL MODEL;

DIGLYCERIDES; DOSAGE FORMS; DRUG COMPOUNDING; GLYCEROL; MODELS, THEORETICAL; NEEDLES; POLYETHYLENE GLYCOLS; SILICONE OILS; TEMPERATURE; VISCOSITY;

EID: 33645235365     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20524     Document Type: Article

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