Antinociception occurs with a reversal in α2-adrenoceptor regulation of TNF production by peripheral monocytes/macrophages from pro- to anti-inflammatory

European Journal of Pharmacology

Volumn 588, Issue 2-3, 2008, Pages 217-231

  Sud, Reeteka ^a   Spengler, Robert N ^a   Nader, Nader D ^a   Ignatowski, Tracey A ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

2 Adrenoceptor; (Rat); Hyperalgesia; Macrophage; Neuropathic pain; Tumor necrosis factor

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; AMITRIPTYLINE; BACTERIUM LIPOPOLYSACCHARIDE; CLONIDINE; RECOMBINANT TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; YOHIMBINE;

ADRENERGIC SYSTEM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD CELL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; HIPPOCAMPUS; HYPERALGESIA; IMMUNOREACTIVITY; IMMUNOREGULATION; INFLAMMATION; LATENT PERIOD; MACROPHAGE; MALE; MICROINJECTION; MONOCYTE; NERVE COMPRESSION; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; PAIN ASSESSMENT; PERIPHERAL NERVOUS SYSTEM; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT; SCIATIC NEUROPATHY; SPRAGUE DAWLEY RAT; TEMPERATURE SENSE; TREATMENT OUTCOME; WITHDRAWAL REFLEX;

AMITRIPTYLINE; ANALGESICS; ANIMALS; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MONOCYTES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; SCIATIC NERVE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 44649105672     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.04.043     Document Type: Article

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