Peripheral antinociceptive action of amitriptyline in the rat formalin test: Involvement of adenosine

Pain

Volumn 80, Issue 1-2, 1999, Pages 45-55

  Sawynok, Jana ^a   Reid, Allison R ^a   Esser, Michael J ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Adenosine; Amitriptyline; Antinociception; Caffeine; Formalin test

Indexed keywords

8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE; ADENOSINE A1 RECEPTOR; AMITRIPTYLINE; CAFFEINE; DIZOCILPINE; FORMALDEHYDE; NALOXONE; PHENTOLAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BEHAVIOR; CHRONIC PAIN; CONTROLLED STUDY; DRUG ACTIVITY; LICKING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE; SUBCUTANEOUS DRUG ADMINISTRATION;

ADENOSINE; AMITRIPTYLINE; ANALGESICS; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CAFFEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; PAIN; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA; RECEPTORS, GLUTAMATE; RECEPTORS, HISTAMINE; RECEPTORS, OPIOID; RECEPTORS, PURINERGIC P1;

EID: 0032990985     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(98)00195-X     Document Type: Article

References (78)

1. Abad, F., Feria, M. and Boada, J., Chronic amitriptyline decreases autotomy following dorsal rhizotomy in rats, Neurosci. Lett., 99 (1989) 187-190.
2. Abbott, F.V., Hong, Y. and Blier, P., Activation of 5-HT2A receptors potentiates pain produced by inflammatory mediators, Neuropharmacology, 35 (1996) 99-110.
3. Acton, J., McKenna, J.E. and Melzack, R., Amitriptyline produces analgesia in the formalin pain test, Exp. Neurol., 117 (1992) 94-96.
4. Ansuategui, M., Naharro, L. and Feria, M., Noradrenergic and opioidergic influences on the antinociceptive effect of clomipramine in the formalin test in rats, Psychopharmacology, 98 (1989) 93-96.
5. Ardid, D., Eschalier, A. and Lavarenne, J., Evidence for a central but not a peripheral analgesic effect of clomipramine in rats, Pain, 45 (1991) 95-100.
6. Ardid, D. and Guilbaud, G., Antinociceptive effects of acute and 'chronic' injections of tricyclic antidepressant drugs in a new model of mononeuropathy in rats, Pain, 49 (1992) 279-287.
7. Arrigoni Martelli, E., Toth, E., Segre, A.D. and Corsico, N., Mechanism of inhibition of experimental inflammation by antidepressant drugs, Eur. J. Pharmacol., 2 (1967) 229-233.
8. Baldessarini, R.J., Drugs and the treatment of psychiatric disorders. In: A.G. Gilman, T.W. Rail, A.S. Nies and P. Taylor (Eds.), The Pharmacological Basic of Therapeutics, 8th edn., Pergamon Press, New York, 1990, pp. 383-435.
9. Bianchi, M., Rossini, G., Sacerdote, P., Panerai, A.E. and Berti, F., Effects of clomipramine and fluoxetine on subcutaneous carrageenin-induced inflammation in the rat, Inflamm. Res., 44 (1995) 466-469.
10. Bianchi, M., Sacerdote, P. and Panerai, A., Clomipramine differently affects inflammatory edema and pain in the rat, Pharmacol. Biochem. Behav., 48 (1994) 1037-1040.
11. Biegon, A. and Samuel, B., Interaction of tricyclic antidepressants with opiate receptors, Biochem. Pharmacol., 29 (1980) 460-461.
12. Botney, M. and Fields, H.L., Amitriptyline potentiates morphine analgesia by a direct action on the central nervous system, Ann. Neurol., 13 (1983) 160-164.
13. Butler, S.H., Weil-Fugazza, J., Godefroy, F. and Besson, J.M., Reduction of arthritis and pain behaviour following chronic administration of amitriptyline or imipramine in rats with adjuvant-induced arthritis, Pain, 23 (1985) 159-175.
14. Bylund, D., Heterogeneity of alpha-2 adrenergic receptors, Pharmacol. Biochem. Behav., 22 (1985) 835-843.
15. 2+ levels in neuronal culture, Eur. J. Pharmacol., 219 (1992) 53-57.
16. Casas, J., Gibert-Rahola, J., Chover, A.J. and Mico, J.A., Test-dependent relationship of the antidepressant and analgesic effects of amitriptyline, Meth. Find. Clin. Pharmacol., 17 (1995) 583-588.
17. Coderre, T.J., Katz, J., Vaccarino, A.L. and Melzack, R., Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence, Pain, 52 (1993) 259-285.
18. Coderre, T.J. and Van Empel, I., The utility of excitatory amino acid (EAA) antagonists as analgesic agents. I. Comparison of the antinociceptive activity of various classes of EAA antagonists in mechanical, thermal and chemical nociceptive tests, Pain, 59 (1994) 345-352.
19. Courteix, C., Bardin, M., Chantelauze, C., Lavarenne, J. and Eschalier, A., Study of the sensitivity of the diabetes-induced pain model in rats to a range of analgesics, Pain, 57 (1994) 153-160.
20. Cronstein, B.N., Adenosine, an endogenous anti-inflammatory agent, J. Appl. Physiol., 76 (1994) 5-13.
21. Dallel, R., Raboisson, P., Clavelou, P., Saade, M. and Woda, A., Evidence for a peripheral origin of the tonic nociceptive response to subcutaneous formalin, Pain, 61 (1995) 11-16.
22. Davidson, E.M., Coggeshall, R.E. and Carlton, S.M., Peripheral NMDA and non-NMDA glutamate receptors contribute to nociceptive behaviors in the rat formalin test, NeuroReport, 8 (1997) 941-946.
23. Deffois, A., Fage, D. and Carter, C., Inhibition of synaptosomal veratridine-induced sodium influx by antidepressants and neuroleptics used in chronic pain, Neurosci. Lett., 220 (1996) 117-120.
24. Devor, M., The pathophysiology of damaged peripheral nerves, In: P.D. Wall and R. Melzack (Ed.), Textbook of Pain, 3rd edn., Churchill Livingstone, New York, 1994, pp. 70-100.
25. Dickenson, A.H. and Sullivan, A.F., Peripheral origins and central modulation of subcutaneous formalin-induced activity of rat dorsal horn neurones, Neurosci. Lett., 83 (1987) 207-211.
26. Doak, G.J. and Sawynok, J., Complex role of peripheral adenosine in the genesis of the response to subcutaneous formalin in the rat, Eur. J. Pharmacol., 281 (1995) 311-318.
27. Doak, G.J. and Sawynok, J., Formalin-induced nociceptive behavior and edema: involvement of multiple peripheral 5-hydroxytryptamine receptor subtypes, Neuroscience, 80 (1997) 939-949.
28. Douglas, W.W. and Ritchie, J.M., The excitatory action of acetylcholine on cutaneous non-myelinated fibres, J. Physiol. (Lond.), 150 (1960) 501-514.
29. Eisenach, J. and Gebhart, G.F., Intrathecal amitriptyline acts as an N-methyl-D-aspartate receptor antagonist in the presence of inflammatory hyperalgesia in rats, Anesthesiology, 83 (1995) 1046-1054.
30. Eschalier, A., Mestre, C., Dubray, C. and Ardid, D., Why are antidepressants effective as pain relief?, CNS Drugs, 2 (1994) 261-267.
31. Eschalier, A., Montastruc, J.L., Devoize, J.L., Rigal, F., Gaillard-Plaza, G. and Pechardre, J.C., Influence of naloxone and methysergide on the analgesic effect of clomipramine in rats, Eur. J. Pharmacol., 74 (1981) 1-7.
32. Fasmer, O.B., Post, C. and Hole, K., Changes in nociception after acute and chronic administration of zimelidine: different effects in the formalin test and the substance P behavioural assay, Neuropharmacology, 26 (1987) 309-312.
33. Frank, R.G., Kashani, J.H., Parker, J.C., Beck, N.C., Brownlee-Duffeck, M., Elliott, T.R., Haut, A.E., Atwood, C., Smith, E. and Kay, D.R., Antidepressant analgesia in rheumatoid arthritis, J. Rheumatol., 15 (1988) 1632-1638.
34. Gringras, M., A clinical trial of tofranil in rheumatic pain in general practice, J. Int. Med. Res., 4 (2) (1976) 41-49.
35. Guieu, R., Peragut, J.C., Roussel, P., Hassani, H., Sampieri, F., Bechis, G., Gola, R. and Rochat, H., Adenosine and neuropathic pain, Pain, 68 (1996) 271-274.
36. Hall, H. and Ögren, S.-O., Effects of antidepressant drugs on different receptors in the brain, Eur. J. Pharmacol., 70 (1981) 393-407.
37. Hill, S.J., Distribution, properties, and functional characteristics of three classes of histamine receptors, Pharmacol. Rev., 42 (1990) 45-83.
38. Isenberg, K.E. and Cicero, T.J., Possible involvement of opiate receptors in the pharmacological profiles of antidepressant compounds, Eur. J. Pharmacol., 103 (1984) 57-63.
39. Jackson, D.L., Graff, C.B., Durnett Richardson, J. and Hargreaves, K.M., Glutamate participates in the peripheral modulation of thermal hyperalgesia in rats, Eur. J. Pharmacol., 284 (1995) 321-325.
40. Jett, M.F., McGuirk, J., Waligora, D. and Hunter, J.C., The effects of mexilitine, desipramine and fluoxetine in rat models involving central sensitization, Pain, 69 (1997) 161-169.
41. Kanof, P.D. and Greengard, P., Brain histamine receptors as targets for antidepressant drugs, Nature, 272 (1978) 329-333.
42. Karlsten, R., Gordh, T. and Post, C., Local antinociceptive and hyperalgesic effects in the formalin test after peripheral administration of adenosine analogues in mice, Pharmacol. Toxicol., 70 (1992) 434-438.
43. Khasar, S.G., Green, P.G., Chou, B. and Levine, J.D., Peripheral nociceptive effects of α-adrenergic receptor agonists in the rat, Neuroscience, 66 (1995) 427-432.
44. Kinnman, E., Nygards, E.-B. and Hansson, P., Peripheral α-adrenoreceptors are involved in the development of capsaicin induced ongoing and stimulus evoked pain in humans, Pain, 69 (1997) 79-85.
45. Lund, A., Mjellem-Joly, N. and Hole, K., Chronic administration of desipramine and zimelidine changes the behavioural response in the formalin test in rats, Neuropharmacology, 30 (1991) 481-487.
46. Maj, J., Gogoz, Z. and Skuza, G., Locomotor hyperactivity induced by MK-801 in rats, Pol. J. Pharmacol. Pharm., 43 (1991) 449-458.
47. Max, M.B., Antidepressants as analgesics. In: H.L. Fields and J.C. Liebs-kind, Progress in Pain Research and Management, Vol. 1, IASP Press, Seattle, 1994, pp. 229-246.
48. McCaslin, P.P., Xu, X.Z., Ho, I.K. and Smith, T.G., Amitriptyline prevents N-methyl-D-aspartate (NMDA)-induced toxicity, does not prevent NMDA-induced elevations of extracellular glutamate, but augments kainate-induced elevations of glutamate, J. Neurochem., 59 (1992) 401-405.
49. McDonald Scott, W.A., The relief of pain with an antidepressant in arthritis, Practitioner, 202 (1969) 802-807.
50. McQuay, H.J., Tramer, M., Nye, B.A., Carrol, D., Wiffen, P.J. and Moore, R.A., A systematic review of antidepressants in neuropathic pain, Pain, 68 (1996) 217-227.
51. Michelson, D., Misiewicz-Poltorak, B., Raybourne, R.B., Gold, P.W. and Sternberg, E.M., Imipramine reduces the local inflammatory response to carrageenin, Agents Actions, 42 (1994) 25-28.
52. Mjellem, N., Lund, A. and Hole, K., Reduction of NMDA-induced behaviour after acute and chronic administration of desipramine in mice, Neuropharmacology, 32 (1993) 591-595.
53. Ninkovic, M. and Hunt, S.P., Opiate and histamine H1 receptors are present on some substance P-containing dorsal root ganglion cells, Neurosci. Lett., 53 (1985) 133-137.
54. Onghena, P. and Van Houdenhove, B., Antidepressant-induced analgesia in chronic non-malignant pain: a meta-analysis of 39 placebo-controlled studies, Pain, 49 (1992) 205-219.
55. Ortego-Alvaro, A., Gibert-Rahola, J., Mellado-Fernández, M. and Chover, A.J., The effects of different monoaminergic antidepressants on the analgesia induced by spinal cord adrenal medullary transplants in the formalin test in rats, Anesth. Analg., 85 (1997) 816-820.
56. Pareek, S.S., Chopde, C.T. and Thakurdesai, P.A., Adenosine enhances analgesic effect of tricyclic antidepressants, Ind. J. Pharmacol., 26 (1994) 159-161.
57. Phillis, J.W., Potentiation of the action of adenosine on cerebral cortical neurones by the tricyclic antidepressants, Br. J. Pharmacol., 83 (1984) 567-575.
58. Phillis, J.W. and Wu, P.H., The effect of various centrally active drugs on adenosine uptake by the central nervous system, Comp. Biochem. Physiol., 72C (1982) 179-187.
59. Poon, A., Sawynok, J., Allen, G.V. and Esser, M.J., Local anti-inflammatory and systemic antinociceptive effects produced by a combination of adenosine kinase and adenosine deaminase inhibitors, Soc. Neurosci. Abstr., 23 (1997) 1814.
60. Reynolds, I.J. and Miller, R.J., Tricyclic antidepressants block N-methyl-D-aspartate receptors: similarities to the action of zinc, Br. J. Pharmacol., 95 (1988) 95-102.
61. Richelson, E. and Pfenning, M., Blockade by antidepressants and related compounds of biogenic amine uptake into rat brain synaptosomes: most antidepressants selectively block norepinephrine uptake, Eur. J. Pharmacol., 104 (1984) 277-286.
62. Saria, A., Martling, C.R., Yan, Z., Theodorsson-Norheim, E., Camse, R. and Lundberg, J.M., Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium and vagal nerve stimulation, Am. Rev. Respir. Dis., 137 (1988) 1330-1335.
63. Sattin, A., Stone, T.W. and Taylor, D.A., Biochemical and electropharmaceutical studies with tricyclic antidepressants in rat and guinea-pig cerebral cortex, Life Sci., 23 (1978) 2621-2626.
64. Sawynok, J., Adenosine receptor activation and nociception, Eur. J. Pharmacol., 317 (1998) 1-11.
65. Sawynok, J., Reid, A. and Poon, A., Peripheral antinociceptive effect of an adenosine kinase inhibitor, with augmentation by an adenosine deaminase inhibitor, in the rat formalin test, Pain, 74 (1998) 75-81.
66. Sierralta, F., Pinardi, G., Mendez, M. and Miranda, H.F., Interaction of opioids with antidepressant-induced antinociception, Psychopharmacology, 122 (1995) 374-378.
67. Spiegel, K., Kalb, R. and Pasternak, G.W., Analgesic activity of tricyclic antidepressants, Ann. Neurol., 13 (1983) 462-465.
68. Stein, C., Peripheral mechanisms of opioid analgesia, Anesth. Analg., 76 (1993) 182-191.
69. Stein, C., Gramsch, C. and Herz, A., Intrinsic mechanisms of antinociception in inflammation: local opioid receptors and β-endorphin, J. Neurosci., 10 (1990) 1292-1298.
70. Stone, T.W. and Taylor, D.A., Antidepressant drugs potentiate suppression by adenosine of neuronal firing in rat cerebral cortex, Neurosci. Lett., 11 (1979) 93-97.
71. Su, X. and Gebhart, G.F., Effects of tricyclic antidepressants on methano-sensitive pelvic nerve afferent fibers innervating the rat colon, Pain, 76 (1998) 105-114.
72. Taylor, B.K., Peterson, M.A. and Basbaum, A.I., Persistent cardiovascular and behavioral nociceptive responses to subcutaneous formalin require peripheral nerve input, J. Neurosci., 15 (1995) 7575-7584.
73. Thorn, J.A. and Jarvis, S.M., Adenosine transporters, Gen. Pharmacol., 27(1996) 613-620.
74. Valverde, O., Mico, J.A., Maldonadpo, R., Mellado, M. and Gibert-Rahola, J., Participation of opioid and monoaminergic mechanisms on the antinociceptive effect induced by tricyclic antidepressants in two behavioural pain tests in mice, Prog. Neuro-Psychopharmacol. Biol. Psychiat., 18 (1994) 1073-1092.
75. Weil-Fugazza, J., Godefroy, F., Manceau, V. and Besson, J.M., Increased norepinephrine and uric acid levels in the spinal cord of arthritic rats, Brain Res., 374 (1986) 190-194.
76. Woolf, C.J. and Doubell, T.P., The pathophysiology of chronic pain -increased sensitivity to low threshold Aβ-fibre inputs, Curr. Opin. Neurobiol., 4 (1994) 525-534.
77. Yamamoto, T. and Yaksh, T.L., Comparison of the antinociceptive effects of pre- and post-treatment with intrathecal morphine and MK801, an NMDA antagonist, on the formalin test in the rat, Anesthesiology, 77 (1992) 757-763.
78. Zhou, S., Bonasera, L. and Carlton, S.M., Peripheral administration of NMDA, AMPA or KA results in pain behaviors in rats, NeuroReport, 7 (1996) 895-900.