Descending modulation from the region of the locus coeruleus on nociceptive sensitivity in a rat model of inflammatory hyperalgesia

Brain Research

Volumn 743, Issue 1-2, 1996, Pages 86-92

  Tsuruoka, Masayoshi ^a   Willis, William D ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

hyperalgesia; inflammation; locus coeruleus; naloxone

Indexed keywords

CARRAGEENAN; NALOXONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; EDEMA; HYPERALGESIA; INFLAMMATION; INTRAPERITONEAL DRUG ADMINISTRATION; LOCUS CERULEUS; MALE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANALYSIS OF VARIANCE; ANIMALS; CARRAGEENAN; DISEASE MODELS, ANIMAL; EFFERENT PATHWAYS; ENDORPHINS; HINDLIMB; HYPERALGESIA; INFLAMMATION; LOCUS COERULEUS; MALE; NALOXONE; PAIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030459419     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01025-6     Document Type: Article

References (39)

1. Attal, N., Kayser, V. and Guilbaud, G., The bidirectional dose-dependent effect of systemic naloxone is also related to the intensity and duration of pain-related disorders: a study in rat model of peripheral mononeuropathy, Brain Res., 525 (1990) 170-174.
2. Clark, F.M. and Proudfit, H.K., The projection of locus coeruleus neurons to the spinal cord in the rat determined by anterograde tracing combined with immunocytochemistry, Brain Res., 538 (1991) 231-245.
3. Clark, F.M. and Proudfit, H.K., Anatomical evidence for genetic differences in the innervation of the rat spinal cord by noradrenergic locus coeruleus neurons, Brain Res., 591 (1992) 44-53.
4. Costello, A.H. and Hargreaves, K.M., Suppression of carrageenan-induced hyperalgesia, hyperthermia and edema by a bradykinin antagonist, Eur. J. Pharmacol., 171 (1989) 259-263.
5. Draisci, G. and Iadarola, M.J., Temporal analysis of increases in c-fos, preprodynorphin and preproenkephalin mRNAs in rat spinal cord, Mol. Brain Res., 6 (1989) 31-37.
6. Fritschy, J.-M. and Grzanna, R., Demonstration of two separate descending noradrenergic pathways to the rat spinal cord: evidence for an intragriseal trajectory of locus coeruleus axons in the superficial layers of the dorsal horn, J. Comp. Neurol., 291 (1990) 553-582.
7. Grzanna, R. and Fritschy, J.-M. Efferent projections of different subpopulations of central noraderenaline neurons, Prog. Brain Res., 88 (1991) 89-101.
8. Hargreaves, K., Dubner, R., Brown, F., Flores, C. and Joris, J., A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia, Pain, 32 (1988) 77-88.
9. Hodge Jr., C.J., Apkarian, A.V., Stevens, R., Vogelsang, G. and Wisnicki, H.J., Locus coeruleus modulation of dorsal horn unit responses to cutaneous stimulation, Brain Res., 204 (1981) 415-420.
10. Hylden, J.L.K., Thomas, D.A., Iadarola, M.J., Nahin, R.L. and Dubner, R., Spinal opioid analgesic effects are enhanced in a model of unilateral inflammation/hyperalgesia: possible involvement of noradrenergic mechanisms, Eur. J. Pharmacol., 194 (1991) 135-143.
11. Iadarola, M.J., Brady, L.S., Draisci, G. and Dubner, R., Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding, Pain, 35 (1988) 313-326.
12. Jones, S.L., Descending noradrenergic influences on pain, Prog. Brain Res., 88 (1991) 381-394.
13. 2-adrenoceptors, Brain Res., 364 (1986) 315-330.
14. Jones, S.L. and Gebhart, G.F., Quantitative characterization of coeruleospinal inhibition of nociceptive transmission in the rat, J. Neurophysiol., 56 (1986) 1397-1410.
15. Jones, S.L. and Gebhart, G.F., Spinal pathways mediating tonic, coeruleospinal, and raphe-spinal descending inhibition in the rat, J. Neurophysiol., 58 (1987) 138-159.
16. Jones, S.L. and Gebhart, G.F., Inhibition of spinal nociceptive transmission from the midbrain, pons and medulla in the rat: activation of descending inhibition by morphine, glutamate and electrical stimulation, Brain Res., 460 (1988) 281-296.
17. Joris, J., Costello, A., Dubner, R. and Hargreaves, K., Opiates suppress carrageenin-induced edema and hyperthermia at doses that inhibit hyperalgesia, Pain, 43 (1990) 95-103.
18. Kayser, V., Besson, J.M. and Guilbaud, G., Analgesia produced by low doses of the opiate antagonist naloxone in arthritic rats is reduced in morphine-tolerant animals, Brain Res., 371 (1986) 37-41.
19. Kayser, V., Besson, J.-M. and Guilbaud, G., Paradoxical effects of low doses of naloxone in experimental models of inflammatory pain. In H.L. Fields and J.-M. Besson (Eds.), Descending Brainstem Controls of Nociceptive Transmission, Progress in Brain Research, Vol. 77, Elsevier, Amsterdam, 1988, pp. 301-312.
20. Kayser, V. and Guilbaud, G., Dose-dependent analgesic and hyperalgesic effects of systemic naloxone in arthritic rats, Brain Res., 226 (1981) 344-348.
21. Kayser, V. and Guilbaud, G., Local and remote modifications of nociceptive sensitivity during carrageenin-induced inflammation in the rat, Pain, 28 (1987) 99-107.
22. Kayser, V. and Guilbaud, G., Physiological relevance and time course of a tonic endogenous opioid modulation of nociceptive messages, based on the effects of naloxone in a rat model of localized hyperalgesic inflammation, Brain Res., 567 (1991) 197-203.
23. Lombard, M.-C. and Besson, J.-M., Electrophysiological evidence for a tonic activity of the spinal cord intrinsic opioid systems in a chronic pain model, Brain Res., 477 (1989) 48-56.
24. Margalit, D. and Segal, M., Apharmacologic study of analgesia produced by stimulation of the nucleus locus coeruleus, Psychopharmacology, 62 (1979) 169-183.
25. Millan, M.J., Czlonkowski, A., Morris, B., Stein, C., Arendt, R., Huber, A., Hollt, V. and Herz, A., Inflammation of the hind limb as a model of unilateral, localized pain: influence on multiple opioid systems in the spinal cord of the rat, Pain, 35 (1988) 299-312.
26. Mokha, S.S., McMillan, J.A. and Iggo, A., Descending control of spinal nociceptive transmission: actions produced on spinal multireceptive neurons from the nuclei locus coeruleus (LC) and raphe magnus (NRM), Exp. Brain Res., 58 (1985) 213-225.
27. Nahin, R.L., Hylden, J.L.K., Iadarola, M.J. and Dubner, R., Peripheral inflammation is associated with increased dynorphin immunoreactivity in both projection and local circuit neurons in the superficial dorsal horn of the rat lumbar spinal cord, Neurosci. Lett., 96 (1989) 247-252.
28. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1986.
29. Proudfit, H.K. and Clark, F.M., The projections of locus coeruleus neurons to the spinal cord, Prog. Brain Res., 85 (1991) 123-141.
30. Ren, K., Williams, G.M., Hylden, J.L.K., Ruda, M.A. and Dubner, R., The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats, Eur. J. Pharmacol., 219 (1992) 235-243.
31. Ruda, M.A., Iadarola, M.J., Cohen, L.V. and Young III, W.S., In situ hybridization histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia, Proc. Natl. Acad. Sci. USA, 85 (1988) 622-626.
32. Segal, M. and Sandberg, D., Analgesia produced by electrical stimulation of catecholamine nuclei in the rat brain, Brain Res., 123 (1977) 369-372.
33. Sluka, K.A. and Westlund, K.N., Spinal projections of the locus coeruleus and the nucleus subcoeruleus in the Harlan and the Sasco Sprague-Dawley rat, Brain Res., 579 (1992) 67-73.
34. Stanfa, L.C., Sullivan, A.F. and Dickenson, A.H., Alterations in neuronal excitability and the potency of spinal mu, delta and kappa opioids after carrageenan-induced inflammation, Pain, 50 (1992) 345-354.
35. Tsuruoka, M. and Willis, W.D., Bilateral lesions in the area of the nucleus locus coeruleus affect the development of hyperalgesia during carrageenan-induced inflammation, Brain Res., (1996) in press.
36. Weihe, E., Millan, M.J., Hollt, V., Nohr, D. and Herz, A., Induction of the gene encoding pro-dynorphin by experimentally induced arthritis enhances staining for dynorphin in the spinal cord of rats, Neuroscience, 31 (1989) 77-95.
37. West, W.L., Yeomans, D.C. and Proudfit, H.K., The function of noradrenergic neurons in mediating antinoceception induced by electrical stimulation of the locus coeruleus in two different sources of Sprague-Dawley rats, Brain Res., 626 (1993) 127-135.
38. Westlund, K.N., Bowker, R.M., Ziegler, M.G. and Coulter, J.D., Noradrenergic projections to the spinal cord in the rat, Brain Res., 263 (1983) 15-31.
39. Zimmerman, M., Ethical guidelines for investigation of experimental pain in conscious animals, Pain, 16 (1983) 109-110.