Acute amitriptyline in a rat model of neuropathic pain: Differential symptom and route effects

Pain

Volumn 80, Issue 3, 1999, Pages 643-653

  Esser, Michael J ^a   Sawynok, Jana ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Amitriptyline; Dorsal root ligation; Neuropathic pain

Indexed keywords

AMITRIPTYLINE; TRICYCLIC ANTIDEPRESSANT AGENT;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DORSAL ROOT; HYPERALGESIA; INTRAPERITONEAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; LUMBAR SPINAL CORD; MALE; MECHANICAL STIMULATION; NERVE INJURY; NERVE LIGATION; NEUROPATHY; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SPINAL NERVE; SUBCUTANEOUS DRUG ADMINISTRATION; TACTILE STIMULATION; THERMAL STIMULATION; TOPICAL DRUG ADMINISTRATION;

AMITRIPTYLINE; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; HEAT; HYPERALGESIA; LIGATION; MALE; NERVE COMPRESSION SYNDROMES; NEURALGIA; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; SPINAL NERVE ROOTS;

EID: 0032910582     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(98)00261-9     Document Type: Article

References (74)

1. 2A receptors potentiates pain produced by inflammatory mediators. Neuropharmacology. 35:1996;99-110.
2. Antesuategui M., Naharro L., Feria M. Noradrenergic and opioidergic influences on the antinociceptive effect of clomipramine in the formalin test in rats. Psychopharmacology. 98:1989;93-96.
3. Ardid D., Eschalier A., Laverenne J. Evidence for a central but not a peripheral analgesic effect of clomipramine in rats. Pain. 45:1991;95-100.
4. Ardid D., Guilbaud G. Antinociceptive effects of acute and 'chronic' injections of tricyclic antidepressant drugs in a new model of mononeuropathy in rats. Pain. 49:1992;279-287.
5. Baldessarini, R.J., Drugs and the treatment of psychiatric disorders. In: A.G. Gilman, T.W. Rall, A.S. Nies and P. Taylor (Eds.), The Pharmacological Basic of Therapeutics, 8th edn., Pergamon Press, New York, 1995, pp. 383-435.
6. Bennett, G.J., Animal models of neuropathic pain. In: G.F. Gebhart, D.L. Hammond, and T.S. Jensen, (Eds.) Proceedings of the 7th World Congress on Pain, IASP Press, Seattle, WA, 1994a, pp. 495-510.
7. Bennett, G.J., Neuropathic Pain, In: P.D. Wall and R. Melzack (Eds.), Textbook of Pain, Churchhill Livingstone, Edinburgh, 1994b, pp. 202-204.
8. Bennett G.J., Xie Y-K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain. 33:1988;87-107.
9. Bian D., Nichols M.L., Ossipov M.H. Lai, J. and Porreca F. Characterization of the antiallodynic efficacy of morphine in a model of neuropathic pain in rats. NeuroReport. 6:1995;1981-1984.
10. 2+ levels in neuronal culture. Eur. J. Pharmacol. 219:1992;53-57.
11. Carlton S.M., Hargett G.L., Coggeshall R.E. Plasticity in α-amino-3-hydroxy-methyl-4-isoxazolepropionic acid receptor subunits in the rat dorsal horn following deafferentation. Neurosci. Lett. 242:1998;21-24.
12. Casas J., Gilbert-Rahola J., Clover A.J., Mico J.A. Test dependent relationship of the antidepressant and analgesic effects of amitriptyline. Meth. Find. Exp. Clin. Pharmacol. 17:1995;583-588.
13. Chaplan S.R., Bach F.W., Pogrel J.W., Chung J.M., Yaksh T.L. Quantitative assessment of allodynia in the rat paw. J. Neurosci. Methods. 53:1994;55-63.
14. Chaplan S.R., Malmberg A.K., Yaksh T.L. Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. J. Pharm. Exp. Ther. 280:1997;829-838.
15. Choi Y., Yoon Y.W., Na H.S., Kim S.H., Chung J.M. Behavioral signs of an ongoing pain and cold allodynia in a rat model of neuropathic pain. Pain. 59:1994;369-376.
16. Coderre T.J., Katz J., Vaccarino A.L., Melzack R. Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain. 52:1993;259-285.
17. Courteix C., Bardin M., Chanteauze C., Lavernne J., Eschalier A. Study of the sensitivity of the diabetes-induced pain model in rats to a range of analgesics. Pain. 57:1994;153-160.
18. Davar G., Hama A., Deykin A., Vos B., Maciewicz R. MK-801 blocks the development of thermal hyperalgesia in a rat model of experimental painful neuropathy. Brain Res. 553:1991;327-330.
19. Davis K.D., Treede R.D., Raja S.N., Meyer R.A., Campbell J.N. Topical application of clonidine relieves hyperalgesia in patients with sympathetically maintained pain. Pain. 47:1991;309-317.
20. Deffois A., Fage D., Carter C. Inhibition of synaptosomal veratridine-induced sodium influx by antidepressants and neuroleptics used in chronic pain. Neurosci. Lett. 220:1996;117-120.
21. Desmeules J.A., Kayser V., Weilfuggaza J., Bertrand A., Guilbaud G. Influence of the sympathetic nervous system in the development of abnormal pain-related behaviors in a rat model of neuropathic pain. Neuroscience. 67:1995;941-951.
22. Dirksen R., Van Diejen D., Van Luijtelaar E.L.J.M., Booij L.H.D.J. Site-and test-dependent antinociceptive efficacy of amitriptyline in rats. Pharm. Biochem. Behav. 47:1994;21-26.
23. Doak G., Sawynok J. Formalin-induced nociceptive behavior and edema: involvement of multiple peripheral 5-hydroxytryptamine receptor subtypes. Neuroscience. 80:1997;939-949.
24. Eisenach J., Gebhart G.F. Intrathecal amitriptyline acts as an N-methyl-D-aspartate receptor antagonist in the presence of inflammatory hyperalgesia in rats. Anesthesiology. 83:1995;1046-1054.
25. Elliott K.J. Taxonomy and mechanisms of neuropathic pain. Semin. Neurol. 14(3):1994;195-205.
26. Eschalier A., Monastruc C., Devoize J.L., Rigal F., Gaillard-Plaza G., Pecharde J.C. Influence of naloxone and methysergide on the analgesic effect of clomipramine in rats. Eur. J. Pharmacol. 74:1981;1-7.
27. Eschalier A., Mestre C., Dubrya C., Ardid D. Why are antidepressants effective as pain relief? CNS Drugs. 2:1994;261-267.
28. Esser M.J., Sawynok J. Amitriptyline decreases thermal hyperalgesia, but not mechanical allodynia in a rat model of neuropathic pain. Soc. Neurosci. Abstr. 23:1997;1538.
29. Gordh T., Karlsten R., Kristensen J. Intervention with spinal NMDA, adenosine, and NO systems for pain modulation. Ann. Med. 27:1995;229-234.
30. Hall H., Ögren S.-O. Effects of antidepressant drugs on different receptors in the brain. Eur. J. Pharmacol. 70:1981;393-407.
31. Hargreaves K., Dubner R., Brown F., Flores C., Jores J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain. 32:1988;77-88.
32. Hwang A.S., Wilcox G.L. Baclofen, gamma-aminobutyric acid-B receptors and substance P in the mouse spinal cord. J. Pharmacol. Exp. Ther. 248:1987;1026-1033.
33. Isenberg, K.E. and Cicero, T.J., Possible involvement of opiate receptors in the pharmacological profiles of antidepressant compound, Eur. J. Pharmacol., 103 (1984).
34. 2+ concentration in the spinal dorsal horn in an animal model of neuropathic pain. Pain. 68:1996;85-96.
35. 2-adrenergic receptor agonists in the rat. Neuroscience. 66:1995;427-432.
36. Kim S.H., Chung J.M. Sympathectomy alleviates mechanical allodynia in an experimental animal model for neuropathy in the rat. Neurosci. Lett. 134:1991;131-134.
37. Kim S.H., Chung J.M. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain. 50:1992;355-363.
38. Kim S.H., Na H.S., Sheen K., Chung J.M. Effects of sympathectomy on a rat model of peripheral neuropathy. Pain. 55:1993;85-92.
39. Kim K.J., Yoon Y.W., Chung J.M. Comparison of three rodent neuropathic pain models. Exp. Brain. Res. 113:1997;200-226.
40. Kinnman E., Levine J.D. Sensory and sympathetic contributions to nerve injury-induced sensory abnormalities in the rat. Neuroscience. 64:1995;751-767.
41. Korzeniewska-Rybicka I., Plaznick A. Analgesic effect of antidepressant drugs. Pharm. Biochem. Behav. 59:1998;331-338.
42. Leem J.W., Choi E.J., Park E.S., Paik K.S. N-Methyl-D-aspartate (NMDA) and non-NMDA antagonists differentially suppress dorsal horn neuron responses to mechanical stimuli in rats with peripheral nerve injury. Neurosci. Lett. 211:1996;37-40.
43. Levine J.D., Taiwo Y.O., Collins S.D., Tam J.K. Noradrenaline hyperalgesia is mediated through interaction with sympathetic postganglionic neuron terminals rather than activation of primary afferent nociceptors. Nature. 323:1986;158-160.
44. MacFarlane B.V., Wright A., O'Callaghan J., Benson H.A.E. Chronic neuropathic pain and its control by drugs. Pharmacol. Ther. 75:1997;1-19.
45. Max M.B. Towards a physiologically based treatment of patients with neuropathic pain. Pain. 42:1990;131-133.
46. McCaslin P.P., Xu X.Z., Ho I.K., Smith T.G. Amitriptyline prevents N-methyl-D-aspartate (NMDA)-induced toxicity, does not prevent NMDA-induced elevations of extracellular glutamate, but augments kainate-induced elevations of glutamate. J. Neurochem. 59:1992;401-405.
47. McLachlan E.M., Janig W., Devor M., Michaelis M. Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature. 363:1993;543-546.
48. McQuay H.L., Carroll D., Jadad A.R., Wiffen P.J., Moore R.A. Anti-convulsant drugs for the management of pain: a systematic review. Br. Med. J. 311:1995;1047-1052.
49. McQuay H.L., Tramer M., Nye B.A., Carroll D., Wiffen P.J., Moore R.A. A systematic review of antidepressants in neuropathic pain. Pain. 68:1996;217-227.
50. Mestre C., Hernández A., Eschalier A., Pelissier T. Effects of clomipramine and desipramine on a C-fiber reflex in rats. Eur. J. Pharm. 335:1997;1-8.
51. Meyer R.R. The pathogenesis of neuropathic pain. Reg. Anaesth. 20:1995;173-184.
52. Neil A., Attal N., Guilbaud G. Effects of guanethidine on sensitization to natural stimuli and self-mutilating behavior in rats with a peripheral neuropathy. Brain Res. 565:1991;237-246.
53. Neuman S., Doubell T.P., Leslie T., Woolf C.J. Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary secondary neuron. Nature. 384:1996;360-363.
54. Nichols M.L., Lopez Y., Ossipov M.H., Bian D., Porreca F. Enhancement of the antiallodynic and antinociceptive efficacy of spinal morphine by antisera to dynorphin A(1-3) or MK-801 in a nerve-ligation model of peripheral neuropathy. Pain. 69:1997;317-322.
55. Onghena P., Van Houdenhove B. Antidepressant-induced analgesia in chronic non-malignant pain: a meta-analysis of 39 placebo-controlled studies. Pain. 49:1992;205-216.
56. Ochoa J.L. Pain mechanisms in neuropathy. Curr. Opin. Neurol. 7:1994;407-414.
57. Ollat H., Cesaro P. Pharmacology of neuropathic pain. Clin. Neuropharm. 18:1995;391-404.
58. Portenoy, R.K., Issues in the management of neuropathic pain. In: A.I. Bausbaum and J.-M. Besson (Eds.), Towards a New Pharmacology of Pain, Wiley, New York, 1991, pp. 393-416.
59. Ramer M.S., Bisby M.A. Rapid sprouting of sympathetic axons in dorsal root ganglia of rats with a chronic constriction injury. Pain. 70:1997;237-244.
60. Richelson E., Pfenning M. Blockade by antidepressants and related compounds of biogenic amine uptake into rat brain synaptosomes: most antidepressants selectively block norepinephrine uptake. Eur. J. Pharmacol. 104:1984;277-286.
61. Rubin G., Kaspi T., Rappapot Z.H., Cohen S., Ravikovitch M., Lomazov P., Devor M. Adrenosensitivity of injured afferent neurons does not require the presence of postganglionic sympathetic terminals. Pain. 72:1997;183-191.
62. Sawynok J., Reid A. Supersensitivity to intrathecal 5-hydroxytryptamine, but not noradrenaline, following depletion of spinal 5-hydroxytryptamine administered in various sites. Naunyn-Schmiedeberg's Arch. Pharmacol. 342:1990;1-8.
63. Sawynok, J., Modulation of nociception by descending serotonergic projections, In: H.G. Baumgarten and M. Göthert (Eds.), Handbook of Experimental Pharmacology, Vol. 29, 1997, pp. 637-653.
64. Sawynok, J., Reid, A. and Esser, M.J., Peripheral antinociceptive action of amitriptyline in the rat formalin test: involvement of adenosine, Pain, 80 (1999) 45-55.
65. Schaible H.G., Schmidt R.F. Time course of mechanosensitivity changes in articular afferents during a developing experimental arthritis. J. Neurophysiol. 60:1988;2180-2195.
66. Seltzer Z., Dubner R., Shir Y. A novel behavior model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain. 43:1990;205-218.
67. Shir Y., Selzer Z. Effects of sympathectomy in a model of causalgiform pain produced by partial sciatic nerve injury in rats. Pain. 45:1991;309-320.
68. Simone D.A. Neural mechanisms of hyperalgesia. Curr. Opin. Neurobiol. 2:1992;479-483.
69. Tal M., Bennett G.J. Neuropathic pain sensations are differentially sensitive to dextrorphan. NeuroReport. 5:1992;1438-1440.
70. 2-adrenoceptors on post-ganglionic sympathetic terminals. Pain. 60:1995;317-327.
71. Woolf C.J., Doubell T.P. The pathophysiology of chronic pain-increased sensitivity to low threshold Aβ-fiber inputs. Curr. Opin. Neurobiol. 4:1994;525-534.
72. Yaksh T.L., Pogrel J.W., Lee Y.W., Chaplan S.R. Reversal of nerve ligation-induced allodynia by spinal alpha-2 adrenoceptor agonists. J. Pharm. Exp. Ther. 272:1995;207-214.
73. Zhou S., Bonasera L., Carlton S.M. Peripheral administration of NMDA, AMPA or KA results in pain behaviors in rats. NeuroReport. 7:1996;895-900.
74. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 16:1983;109-111.