메뉴 건너뛰기




Volumn 59, Issue 1, 2004, Pages 50-61

Dynamics of cell adhesion and motility in living cells is altered by a single amino acid change in E-cadherin fused to enhanced green fluorescent protein

Author keywords

Cell motility; E cadherin mutation; EGF receptor; Time lapse imaging; Tyrphostin AG 1478

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; AMINO ACID; BETA CATENIN; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; UVOMORULIN;

EID: 4444369824     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/cm.20019     Document Type: Article
Times cited : (13)

References (54)
  • 2
    • 0030464473 scopus 로고    scopus 로고
    • Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion
    • Adams CL, Nelson WJ, Smith SJ. 1996. Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion. J Cell Biol 135:1899-1911.
    • (1996) J Cell Biol , vol.135 , pp. 1899-1911
    • Adams, C.L.1    Nelson, W.J.2    Smith, S.J.3
  • 3
    • 0032563564 scopus 로고    scopus 로고
    • Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein
    • Adams CL, Chen YT, Smith SJ, Nelson WJ. 1998. Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein. J Cell Biol 142:1105-1119.
    • (1998) J Cell Biol , vol.142 , pp. 1105-1119
    • Adams, C.L.1    Chen, Y.T.2    Smith, S.J.3    Nelson, W.J.4
  • 4
    • 0035158750 scopus 로고    scopus 로고
    • RAC1 regulates adherens junctions through endocytosis of E-cadherin
    • Akhtar N, Hotchin NA. 2001. RAC1 regulates adherens junctions through endocytosis of E-cadherin. Mol Biol Cell 12:847-862.
    • (2001) Mol Biol Cell , vol.12 , pp. 847-862
    • Akhtar, N.1    Hotchin, N.A.2
  • 7
    • 0032619088 scopus 로고    scopus 로고
    • Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online
    • Becker KF, Reich U, Schott C, Becker I, Berx G, van Roy F, Höfler H. 1999. Identification of eleven novel tumor-associated E-cadherin mutations. Mutations in brief no. 215. Online. Hum Mutat 13:171.
    • (1999) Hum Mutat , vol.13 , pp. 171
    • Becker, K.F.1    Reich, U.2    Schott, C.3    Becker, I.4    Berx, G.5    Van Roy, F.6    Höfler, H.7
  • 8
    • 0027507028 scopus 로고
    • Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene
    • Behrens J, Vakaet L, Friis R, Winterhager E, Van Roy F, Mareel MM, Birchmeier W. 1993. Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol 120:757-766.
    • (1993) J Cell Biol , vol.120 , pp. 757-766
    • Behrens, J.1    Vakaet, L.2    Friis, R.3    Winterhager, E.4    Van Roy, F.5    Mareel, M.M.6    Birchmeier, W.7
  • 9
    • 0031686121 scopus 로고    scopus 로고
    • Mutations of the human E-cadherin (CDH1) gene
    • Berx G, Becker KF, Hofler H, van Roy F. 1998. Mutations of the human E-cadherin (CDH1) gene. Hum Mutat 12:226-237.
    • (1998) Hum Mutat , vol.12 , pp. 226-237
    • Berx, G.1    Becker, K.F.2    Hofler, H.3    Van Roy, F.4
  • 11
    • 0029998613 scopus 로고    scopus 로고
    • Lateral dimerization is required for the homophilic binding activity of C-cadherin
    • Brieher WM, Yap AS, Gumbiner BM. 1996. Lateral dimerization is required for the homophilic binding activity of C-cadherin. J Cell Biol 135:487-496.
    • (1996) J Cell Biol , vol.135 , pp. 487-496
    • Brieher, W.M.1    Yap, A.S.2    Gumbiner, B.M.3
  • 13
    • 0031908252 scopus 로고    scopus 로고
    • EGF stimulates an increase in actin nucleation and filament number at the leading edge of the lamellipod in mammary adenocarcinoma cells
    • Chan AY, Raft S, Bailly M, Wyckoff JB, Segall JE, Condeelis JS. 1998. EGF stimulates an increase in actin nucleation and filament number at the leading edge of the lamellipod in mammary adenocarcinoma cells. J Cell Sci 111:199-211.
    • (1998) J Cell Sci , vol.111 , pp. 199-211
    • Chan, A.Y.1    Raft, S.2    Bailly, M.3    Wyckoff, J.B.4    Segall, J.E.5    Condeelis, J.S.6
  • 14
    • 0025773459 scopus 로고
    • Cell-cell contacts mediated by E-cadherin (uvomorulin) restrict invasive behavior of L-cells
    • Chen WC, Obrink B. 1991. Cell-cell contacts mediated by E-cadherin (uvomorulin) restrict invasive behavior of L-cells. J Cell Biol 114:319-327.
    • (1991) J Cell Biol , vol.114 , pp. 319-327
    • Chen, W.C.1    Obrink, B.2
  • 19
    • 0347955452 scopus 로고    scopus 로고
    • Effect of wild-type and mutant E-cadherin on cell proliferation and responsiveness to the chemotherapeutic agents cisplatin, etoposide, and 5-fluorouracil
    • Fricke E, Hermannstadter C, Keller G, Fuchs M, Brunner I, Busch R, Hofler H, Becker KF, Luber B. 2004. Effect of wild-type and mutant E-cadherin on cell proliferation and responsiveness to the chemotherapeutic agents cisplatin, etoposide, and 5-fluorouracil. Oncology 66:150-159.
    • (2004) Oncology , vol.66 , pp. 150-159
    • Fricke, E.1    Hermannstadter, C.2    Keller, G.3    Fuchs, M.4    Brunner, I.5    Busch, R.6    Hofler, H.7    Becker, K.F.8    Luber, B.9
  • 24
    • 0035976712 scopus 로고    scopus 로고
    • Single amino acid substitutions in conserved extracellular domains of E-cadherin differ in their functional consequences
    • Handschuh G, Luber B, Hutzler P, Höfler H, Becker KF. 2001. Single amino acid substitutions in conserved extracellular domains of E-cadherin differ in their functional consequences. J Mol Biol 314:445-454.
    • (2001) J Mol Biol , vol.314 , pp. 445-454
    • Handschuh, G.1    Luber, B.2    Hutzler, P.3    Höfler, H.4    Becker, K.F.5
  • 25
    • 0034695913 scopus 로고    scopus 로고
    • Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis
    • Hazan RB, Phillips GR, Qiao RF, Norton L, Aaronson SA. 2000. Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol 148:779-790.
    • (2000) J Cell Biol , vol.148 , pp. 779-790
    • Hazan, R.B.1    Phillips, G.R.2    Qiao, R.F.3    Norton, L.4    Aaronson, S.A.5
  • 26
    • 0033581834 scopus 로고    scopus 로고
    • Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells: Regulation by Rho, Rac and Rab small G proteins
    • Kamei T, Matozaki T, Sakisaka T, Kodama A, Yokoyama S, Peng YF, Nakano K, Takaishi K, Takai Y. 1999. Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells: regulation by Rho, Rac and Rab small G proteins. Oncogene 18:6776-6784.
    • (1999) Oncogene , vol.18 , pp. 6776-6784
    • Kamei, T.1    Matozaki, T.2    Sakisaka, T.3    Kodama, A.4    Yokoyama, S.5    Peng, Y.F.6    Nakano, K.7    Takaishi, K.8    Takai, Y.9
  • 27
    • 0027185632 scopus 로고
    • From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion
    • Kemler R. 1993. From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet 9:317-321.
    • (1993) Trends Genet , vol.9 , pp. 317-321
    • Kemler, R.1
  • 28
    • 0028979956 scopus 로고
    • Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin
    • Knudsen KA, Soler AP, Johnson KR, Wheelock MJ. 1995. Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol 130:67-77.
    • (1995) J Cell Biol , vol.130 , pp. 67-77
    • Knudsen, K.A.1    Soler, A.P.2    Johnson, K.R.3    Wheelock, M.J.4
  • 30
    • 0001331879 scopus 로고    scopus 로고
    • Recycling of E-cadherin: A potential mechanism for regulating cadherin dynamics
    • Le TL, Yap AS, Stow JL. 1999. Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics. J Cell Biol 146: 219-232.
    • (1999) J Cell Biol , vol.146 , pp. 219-232
    • Le, T.L.1    Yap, A.S.2    Stow, J.L.3
  • 32
    • 0027456957 scopus 로고
    • Rapid effects of EGF on cytoskeletal structures and adhesive properties of highly metastatic rat mammary adenocarcinoma cells
    • Lichtner RB, Wiedemuth M, Noeske-Jungblut C, Schirrmacher V. 1993. Rapid effects of EGF on cytoskeletal structures and adhesive properties of highly metastatic rat mammary adenocarcinoma cells. Clin Exp Metastasis 11:113-125.
    • (1993) Clin Exp Metastasis , vol.11 , pp. 113-125
    • Lichtner, R.B.1    Wiedemuth, M.2    Noeske-Jungblut, C.3    Schirrmacher, V.4
  • 33
    • 0034102255 scopus 로고    scopus 로고
    • Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate
    • Luber B, Candidus S, Handschuh G, Mentele E, Hutzler P, Feller S, Voss J, Höfler H, Becker KF. 2000. Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate. Cell Adhes Commun 7:391-408.
    • (2000) Cell Adhes Commun , vol.7 , pp. 391-408
    • Luber, B.1    Candidus, S.2    Handschuh, G.3    Mentele, E.4    Hutzler, P.5    Feller, S.6    Voss, J.7    Höfler, H.8    Becker, K.F.9
  • 35
    • 0029980542 scopus 로고    scopus 로고
    • Structural basis of calcium-induced E-cadherin rigidification and dimerization
    • Nagar B, Overduin M, Ikura M, Rini JM. 1996. Structural basis of calcium-induced E-cadherin rigidification and dimerization. Nature 380:360-364.
    • (1996) Nature , vol.380 , pp. 360-364
    • Nagar, B.1    Overduin, M.2    Ikura, M.3    Rini, J.M.4
  • 36
    • 0033230475 scopus 로고    scopus 로고
    • N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression
    • Nieman MT, Prudoff RS, Johnson KR, Wheelock MJ. 1999. N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. J Cell Biol 147:631-644.
    • (1999) J Cell Biol , vol.147 , pp. 631-644
    • Nieman, M.T.1    Prudoff, R.S.2    Johnson, K.R.3    Wheelock, M.J.4
  • 37
    • 0024451982 scopus 로고
    • The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species
    • Ozawa M, Baribault H, Kemler R. 1989. The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. Embo J 8:1711-1717.
    • (1989) Embo J , vol.8 , pp. 1711-1717
    • Ozawa, M.1    Baribault, H.2    Kemler, R.3
  • 38
    • 0025612251 scopus 로고
    • Single amino acid substitutions in one Ca2+ binding site of uvomorulin abolish the adhesive function
    • Ozawa M, Engel J, Kemler R. 1990. Single amino acid substitutions in one Ca2+ binding site of uvomorulin abolish the adhesive function. Cell 63:1033-1038.
    • (1990) Cell , vol.63 , pp. 1033-1038
    • Ozawa, M.1    Engel, J.2    Kemler, R.3
  • 39
    • 0035801516 scopus 로고    scopus 로고
    • An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration
    • Palacios F, Price L, Schweitzer J, Collard JG, D'Souza-Schorey C. 2001. An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration. Embo J 20:4973-4986.
    • (2001) Embo J , vol.20 , pp. 4973-4986
    • Palacios, F.1    Price, L.2    Schweitzer, J.3    Collard, J.G.4    D'Souza-Schorey, C.5
  • 40
    • 0038418651 scopus 로고    scopus 로고
    • Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: The initial fate of unbound E-cadherin
    • Paterson AD, Parton RG, Ferguson C, Stow JL, Yap AS. 2003. Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: the initial fate of unbound E-cadherin. J Biol Chem 278:21050-21057.
    • (2003) J Biol Chem , vol.278 , pp. 21050-21057
    • Paterson, A.D.1    Parton, R.G.2    Ferguson, C.3    Stow, J.L.4    Yap, A.S.5
  • 41
    • 0034731148 scopus 로고    scopus 로고
    • Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation
    • Pece S, Gutkind JS. 2000. Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation. J Biol Chem 275:41227-41233.
    • (2000) J Biol Chem , vol.275 , pp. 41227-41233
    • Pece, S.1    Gutkind, J.S.2
  • 42
    • 0033119626 scopus 로고    scopus 로고
    • A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation
    • Pertz O, Bozic D, Koch AW, Fauser C, Brancaccio A, Engel J. 1999. A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation. Embo J 18:1738-1747.
    • (1999) Embo J , vol.18 , pp. 1738-1747
    • Pertz, O.1    Bozic, D.2    Koch, A.W.3    Fauser, C.4    Brancaccio, A.5    Engel, J.6
  • 43
    • 0028093281 scopus 로고
    • Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding
    • Pokutta S, Herrenknecht K, Kemler R, Engel J. 1994. Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding. Eur J Biochem 223:1019-1026.
    • (1994) Eur J Biochem , vol.223 , pp. 1019-1026
    • Pokutta, S.1    Herrenknecht, K.2    Kemler, R.3    Engel, J.4
  • 44
    • 0028981208 scopus 로고
    • Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex
    • Rimm DL, Koslov ER, Kebriaei P, Cianci CD, Morrow JS. 1995. Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc Natl Acad Sci USA 92:8813-8817.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8813-8817
    • Rimm, D.L.1    Koslov, E.R.2    Kebriaei, P.3    Cianci, C.D.4    Morrow, J.S.5
  • 48
    • 0025933683 scopus 로고
    • Biosynthesis of the cell adhesion molecule uvomorulin (E-cadherin) in Madin-Darby canine kidney epithelial cells
    • Shore EM, Nelson WJ. 1991. Biosynthesis of the cell adhesion molecule uvomorulin (E-cadherin) in Madin-Darby canine kidney epithelial cells. J Biol Chem 266:19672-19680.
    • (1991) J Biol Chem , vol.266 , pp. 19672-19680
    • Shore, E.M.1    Nelson, W.J.2
  • 50
    • 0032953786 scopus 로고    scopus 로고
    • E-cadherin functions as a cis-dimer at the cell-cell adhesive interface in vivo
    • Takeda H, Shimoyama Y, Nagafuchi A, Hirohashi S. 1999. E-cadherin functions as a cis-dimer at the cell-cell adhesive interface in vivo. Nat Struct Biol 6:310-312.
    • (1999) Nat Struct Biol , vol.6 , pp. 310-312
    • Takeda, H.1    Shimoyama, Y.2    Nagafuchi, A.3    Hirohashi, S.4
  • 51
    • 0025894092 scopus 로고
    • Cadherin cell adhesion receptors as a morphogenetic regulator
    • Takeichi M. 1991. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251:1451-1455.
    • (1991) Science , vol.251 , pp. 1451-1455
    • Takeichi, M.1
  • 53
    • 0025119463 scopus 로고
    • Scatter factor: Molecular characteristics and effect on the invasiveness of epithelial cells
    • Weidner KM, Behrens J, Vandekerckhove J, Birchmeier W. 1990. Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol 111:2097-2108.
    • (1990) J Cell Biol , vol.111 , pp. 2097-2108
    • Weidner, K.M.1    Behrens, J.2    Vandekerckhove, J.3    Birchmeier, W.4
  • 54
    • 0031149109 scopus 로고    scopus 로고
    • Lateral clustering of the adhesive ectodomain: A fundamental determinant of cadherin function
    • Yap AS, Brieher WM, Pruschy M, Gumbiner BM. 1997. Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function. Curr Biol 7:308-315.
    • (1997) Curr Biol , vol.7 , pp. 308-315
    • Yap, A.S.1    Brieher, W.M.2    Pruschy, M.3    Gumbiner, B.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.