Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility

Oncogene

Volumn 18, Issue 30, 1999, Pages 4301-4312

  Handschuh, Gabriele ^a   Candidus, Sonja ^b   Luber, Birgit ^a   Reich, Ulrike ^a   Schott, Christina ^b   Oswald, Sandra ^a   Becke, Helma ^a   Hutzler, Peter ^a   Birchmeier, Walter ^c   Höfler, Heinz ^a,b   Becker, Karl Friedrich ^a,b  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Cell adhesion; E cadherin; Gastric carcinoma; Morphology; Motility

Indexed keywords

CALCIUM; COMPLEMENTARY DNA; MUTANT PROTEIN; UVOMORULIN;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; BREAST CARCINOMA; CELL ADHESION; CELL MOTILITY; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; EXON; GENE DELETION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; L CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; STOMACH CANCER;

ACTINS; ANIMALS; CADHERINS; CELL ADHESION; CELL MOVEMENT; EXONS; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MICE; MICROSCOPY, CONFOCAL; MODELS, GENETIC; MUTATION; POINT MUTATION; STOMACH NEOPLASMS; TRANSFECTION; TUMOR CELLS, CULTURED; WOUND HEALING;

EID: 0033615002     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202790     Document Type: Article

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